Chloride channel-mediated brain glioma targeting of chlorotoxin-modified doxorubicine-loaded liposomes

Journal of Controlled Release

Volumn 152, Issue 3, 2011, Pages 402-410

  Xiang, Yu ^a   Liang, Liang ^a   Wang, Xueqing ^a   Wang, Jiancheng ^a   Zhang, Xuan ^a   Zhang, Qiang ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Chlorotoxin; Doxorubicin; Glioma; Liposomes; Targeting delivery

Indexed keywords

ANTICANCER DRUG; BALB/C MICE; BIODISTRIBUTIONS; CELL LINES; CHLOROTOXIN; DELIVERY SYSTEMS; DOXORUBICIN; ENCAPSULATION EFFICIENCY; ENDOTHELIAL CELL LINE; FLUORESCENT PROBES; GLIOMA; GLIOMA CELL LINES; GLIOMA CELLS; GOOD CORRELATIONS; HIGH SPECIFICITY; IN-VITRO; INTRACRANIAL TUMORS; LOADING CAPACITIES; PHYSICO-CHEMICAL CHARACTERIZATION; TARGETING DELIVERY; TUMOR GROWTH; TUMOR MODELS; TUMOR XENOGRAFTS; UNIFORM DISTRIBUTION;

CELL CULTURE; CHLORINE COMPOUNDS; CONFOCAL MICROSCOPY; ENCAPSULATION; ENDOTHELIAL CELLS; FLOW CYTOMETRY; LIPOSOMES; MAMMALS; PHOSPHOLIPIDS;

TUMORS;

CHLORIDE CHANNEL; CHLOROTOXIN; DOXORUBICIN; LIPOSOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD TOXICITY; CANCER CELL CULTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENCAPSULATION; ENDOTHELIUM CELL; FLOW CYTOMETRY; GLIOMA; GLIOMA CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PARTICLE SIZE; PHARMACODYNAMICS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SPECTROFLUOROMETRY; TREATMENT DURATION; TUMOR LOCALIZATION; TUMOR MODEL; TUMOR VOLUME; TUMOR XENOGRAFT; ZETA POTENTIAL;

ANIMALS; BIOLOGICAL AVAILABILITY; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; CHLORIDE CHANNELS; CHOLESTEROL; DOXORUBICIN; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; ENDOTHELIAL CELLS; FLOW CYTOMETRY; FLUORESCENT DYES; GLIOMA; HUMANS; INHIBITORY CONCENTRATION 50; LEUKOCYTE COUNT; LIPOSOMES; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MICROSCOPY, FLUORESCENCE; PARTICLE SIZE; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; RATS; SCORPION VENOMS; SPECTROMETRY, FLUORESCENCE; STATIC ELECTRICITY; WHOLE BODY IMAGING; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79958231722     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.03.014     Document Type: Article

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