Prognostic significance of tissue transglutaminase in drug resistant and metastatic breast cancer

Clinical Cancer Research

Volumn 10, Issue 23, 2004, Pages 8068-8076

  Mehta, Kapil ^a   Fok, Jansina ^a   Miller, Fred R ^b   Koul, Dimpy ^a   Sahin, Aysegul A ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CELL CLONE; CELL IMMORTALIZATION; CELL STRAIN MCF10A; CELL STRAIN MDA MB 231; CELL STRAIN MDA231 CL 16; CELL STRAIN MDA231 CL 9; CLINICAL ARTICLE; DRUG RESISTANCE; DRUG SENSITIVITY; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; METASTASIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TISSUE LEVEL;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BREAST NEOPLASMS; CELL MOVEMENT; CELL SURVIVAL; COLLAGEN; DISEASE PROGRESSION; DOXORUBICIN; DRUG COMBINATIONS; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GTP-BINDING PROTEINS; HUMANS; LAMININ; LYMPHATIC METASTASIS; MICE; MICE, NUDE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROTEOGLYCANS; TRANSGLUTAMINASES; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 9744274000     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-1107     Document Type: Article

References (43)

1. Stewart BW, Kleihues P. Human cancers by organ sites. In: Stewart BW, Kleihues P, editors. World Cancer Report. Lyon, France: IARC; 2003. p. 181-270.
2. Lehnert M. Clinical multidrug resistance in cancer: a multifactorial problem. Eur J Cancer 1996;32:912-20.
3. Ling V. Multidrug resistance: molecular mechanisms and clinical relevance. Cancer Chemother Pharmacol 1997;40:S3-8.
4. Liang Y, McDonnell S, Clynes M. Examining the relationship between cancer invasion/metastasis and drug resistance. Curr Cancer Drug Targets 2002;2:257-77.
5. Kerbel RS, Kobayashi H, Graham CH. Intrinsic or acquired drug resistance and metastasis: are they linked phenotypes? J Cell Biochem 1994;56:37-47.
6. Bae SN, Arand G, Azzam H, et al. Molecular and cellular analysis of basement membrane invasion by human breast cancer cells in Matrigel-based in vitro assays. Breast Cancer Res Treat 1993;24:241-55.
7. Chen JS, Agarwal N, Mehta K. Multidrug-resistant MCF-7 breast cancer cells contain deficient intracellular calcium pools. Breast Cancer Res Treat 2002;71:237-47.
8. Devarajan E, Chen J, Multani AS, et al. Human breast cancer MCF-7 cell line contains inherently drug-resistant subclones with distinct genotypic and phenotypic features. Int J Oncol 2002;20:913-20.
9. Mehta K, Devarajan E, Chen J, Multani A, Pathak S. Multidrug-resistant MCF-7 cells: an identity crisis. J Natl Cancer Inst (Bethesda) 2002;94:1652-4.
10. Miller FR, Santner SJ, Tait L, Dawson PJ. MCFIODCIS.com xenograft model of human comedo ductal carcinoma in situ. J Natl Cancer Inst (Bethesda) 2000;92:1185-6.
11. Santner SJ, Dawson PJ, Tait L, et al. Malignant MCFIOCAI cell lines derived from premalignant human breast epithelial MCFIOAT cells. Breast Cancer Res Treat 2001;65:101-10.
12. Koul D, Parathasarathy R, Shen R, et al. Suppression of metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN. Oncogene 2001;20:6669-78.
13. Aoudjit F, Vuori K. Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells. Oncogene 2001;20:4995-04.
14. Mehta K. High levels of transglutaminase expression in doxorubicin-resistant human breast carcinoma cells. Int J Cancer 1994;58:400-6.
15. Akimov SS, Belkin AM. Cell surface tissue transglutaminase is involved in adhesion and migration of monocytic cells on fibronectin. Blood 2001;98:1567-76.
16. Akimov SS, Belkin AM. Cell-surface transglutaminase promotes fibronectin assembly via interaction with the gelatin-binding domain of fibronectin: a role in TGFbeta-dependent matrix deposition. J Cell Sci 2001;114:2989-3000.
17. Akimov SS, Krylov D, Fleischman LF, Belkin AM. Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin. J Cell Biol 2000;148:825-38.
18. Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2002;2:277-88.
19. Han JA, Park SC. Reduction of transglutaminase 2 expression is associated with an induction of drug sensitivity in the PC-14 human lung cancer cell line. J Cancer Res Clin Oncol 1999;125:89-95.
20. Lorand L, Graham RM. Transglutaminases: crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol 2003;4:140-56.
21. Melino G, Annicchiarico-Petruzzelli M, Piredda L, et al. Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells. Mol Cell Biol 1994;14:6584-96.
22. Melino G, Piacentini M. 'Tissue' transglutaminase in cell death: a downstream or a multifunctional upstream effector? FEBS Lett 1998;430:59-63.
23. Autuori F, Farrace MG, Oliverio S, Piredda L, Piacentini M. "Tissue" transglutaminase and apoptosis. Adv Biochem Eng Biotechnol 1998;62:129-36.
24. Fesus L, Madi A, Balajthy Z, Nemes Z, Szondy Z. Transglutaminase induction by various cell death and apoptosis pathways. Experientia 1996;52:942-9.
25. De Laurenzi V, Melino G. Gene disruption of tissue transglutaminase. Mol Cell Biol 2001;21:148-55.
26. Nanda M, Ismaa SE, Owen WA, et al. Targeted inactivation of Gh/tissue transglutaminase II. J Biol Chem 2001;276:20673-8.
27. Antonyak MA, McNeill CJ, Wakshlag JJ, Boehm JE, Cerione RA. Activation of the Ras-ERK pathway inhibits retinoic acid-induced stimulation of tissue transglutaminase expression in NIH3T3 cells. J Biol Chem 2003;278:15859-66.
28. Antonyak MA, Singh US, Lee DA, et al. Effects of tissue transglutaminase on retinoic acid-induced cellular differentiation and protection against apoptosis. J Biol Chem 2001;276:33582-7.
29. Boehm JE, Singh U, Combs C, Antonyak MA, Cerione RA. Tissue transglutaminase protects against apoptosis by modifying the tumor suppressor protein p110 Rb. J Biol Chem 2002;277:20127-30.
30. Milakovic T, Tucholski J, McCoy E, Johnson GV. Intracellular localization and activity state of tissue transglutaminase differentially impacts cell death. J Biol Chem 2004;279:8715-22.
31. Chen J, Kanopleva M, Multani A, Pathak S, Mehta K. Drug resistant breast cancer MCF-7 cells are paradoxically sensitive to apoptosis. J Cell Physiol 2004;200:223-34.
32. Piredda L, Farrace MG, Lo Bello M, et al. Identification of 'tissue' transglutaminase binding proteins in neural cells committed to apoptosis. FASEB J 1999;13:355-64.
33. Piacentini M, Farrace MG, Piredda L, et al. Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stress. J Neurochem 2002;81:1061-72.
34. Parise LV, Lee J, Juliano RL. New aspects of integrin signaling in cancer. Semin Cancer Biol 2000;10:407-14.
35. Juliano RL. Integrin signals and tumor growth control. Princess Takamatsu Symp 1994;24:118-24.
36. Juliano R. Signal transduction by integrins and its role in the regulation of tumor growth. Cancer Metastasis Rev 1994;13:25-30.
37. Howe A, Aplin AE, Alahari SK, Juliano RL. Integrin signaling and cell growth control. Curr Opin Cell Biol 1998;10:220-31.
38. Schlaepfer DD, Hauck CR, Sieg DJ. Signaling through focal adhesion kinase. Prog Biophys Mol Biol 1999;71:435-78.
39. Guan JL. Role of focal adhesion kinase in integrin signaling. Int J Biochem Cell Biol 1997;29:1085-96.
40. Mohan K, Pinto D, Issekutz TB. Identification of tissue transglutaminase as a novel molecule involved in human CD8+ T cell transendothelial migration. J Immunol 2003;171:3179-86.
41. Priglinger SG, Alge CS, Neubauer AS, et al. TGF-beta2-induced cell surface tissue transglutaminase increases adhesion and migration of RPE cells on fibronectin through the gelatin-binding domain. Investig Ophthal Vis Sci 2004;45:955-63.
42. Khera V, Mehta K. Transglutaminase levels and immunologic functions of BCG-elicited mouse peritoneal macrophages isolated by centrifugal elutriation. J Leukoc Biol 1989;45:434-43.
43. Jiang D, Ying W, Lu Y, et al. Identification of metastasis-associated proteins by proteomic analysis and functional exploration of interleukin-18 in metastasis. Proteomics 2003;3:724-37.