Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent artemisinin

Phytomedicine

Volumn 18, Issue 11, 2011, Pages 959-969

  Efferth, Thomas ^a   Herrmann, Florian ^b   Tahrani, Ahmed ^b   Wink, Michael ^b  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Artemisinin; Cancer; Drug resistance; Microarray; Natural products; Pharmacogenomics; Trypanosoma

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ARTEMISIA ANNUA EXTRACT; ARTEMISININ; ARTEMISITENE; ARTESUNATE; CAMPTOTHECIN; CINEOLE; DICHLOROMETHANE; IRINOTECAN; METHANOL; SCOPOLETIN; TOPOTECAN;

ARTEMISIA ANNUA; ARTICLE; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS RESISTANCE; DRUG CYTOTOXICITY; DRUG SENSITIVITY; DRUG STRUCTURE; HELA CELL; HUMAN; HUMAN CELL; IC 50; MALARIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TEA; TRYPANOSOMA BRUCEI; TUMOR CELL LINE; UNINDEXED SEQUENCE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; ARTEMISIA ANNUA; ARTEMISININS; CYCLOHEXANOLS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; MOLECULAR STRUCTURE; MONOTERPENES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARASITIC SENSITIVITY TESTS; PLANT EXTRACTS; SCOPOLETIN; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI;

ARTEMISIA ANNUA; TRYPANOSOMA;

EID: 80051887433     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2011.06.008     Document Type: Article

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