Prolonged exposure to high dietary lipids is not associated with lipotoxicity in heart failure

Journal of Molecular and Cellular Cardiology

Volumn 46, Issue 6, 2009, Pages 883-890

  Rennison, Julie H ^a   McElfresh, Tracy A ^a   Chen, Xiaoqin ^a   Anand, Vijay R ^a   Hoit, Brian D ^a,b   Hoppel, Charles L ^a   Chandler, Margaret P ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

Dietary fat; Heart failure; Lipotoxicity; Mitochondria; Oxidative phosphorylation

Indexed keywords

MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; PALMITOYLCARNITINE; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CONTRACTILITY; LIPID DIET; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT;

ACYL-COA DEHYDROGENASE; ACYL-COA DEHYDROGENASE, LONG-CHAIN; ADIPONECTIN; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; BUTYRYL-COA DEHYDROGENASE; DIETARY FATS; ECHOCARDIOGRAPHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FATTY ACIDS, NONESTERIFIED; HEMODYNAMICS; INSULIN; LEPTIN; MALE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; ORGAN SIZE; OXIDATIVE PHOSPHORYLATION; RATS; RATS, WISTAR;

ANIMALIA; RATTUS;

EID: 67349191501     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.02.019     Document Type: Article

References (48)

1. Lopaschuk G.D., Folmes C.D., and Stanley W.C. Cardiac energy metabolism in obesity. Circ. Res. 101 (2007) 335-347
2. Boudina S., Sena S., Theobald H., Sheng X., Wright J.J., Hu X.X., et al. Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. Diabetes 56 (2007) 2457-2466
3. Stanley W.C., Recchia F.A., and Lopaschuk G.D. Myocardial substrate metabolism in the normal and failing heart. Physiol. Rev. 85 (2005) 1093-1129
4. Korge P., Honda H.M., and Weiss J.N. Effects of fatty acids in isolated mitochondria: implications for ischemic injury and cardioprotection. Am. J. Physiol. Heart. Circ. Physiol. 285 (2003) H259-H269
5. Oliver F.J., Salto R., Sola M.M., and Vargas A.M. Mitochondrial pyruvate metabolism in liver and kidney during acidosis. Cell. Biochem. Funct. 12 (1994) 229-235
6. Korvald C., Elvenes O.P., and Myrmel T. Myocardial substrate metabolism influences left ventricular energetics in vivo. Am. J. Physiol. Heart. Circ. Physiol. 278 (2000) H1345-H1351
7. Lehman J.J., Boudina S., Banke N.H., Sambandam N., Han X., Young D.M., et al. The transcriptional coactivator PGC-1alpha is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis. Am. J. Physiol. Heart. Circ. Physiol. 295 (2008) H185-H196
8. Finck B.N., Han X., Courtois M., Aimond F., Nerbonne J.M., Kovacs A., et al. A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 1226-1231
9. Zhou Y.T., Grayburn P., Karim A., Shimabukuro M., Higa M., Baetens D., et al. Lipotoxic heart disease in obese rats: implications for human obesity. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 1784-1789
10. Chiu H.C., Kovacs A., Ford D.A., Hsu F.F., Garcia R., Herrero P., et al. A novel mouse model of lipotoxic cardiomyopathy. J. Clin. Invest. 107 (2001) 813-822
11. Howard B.V., Van Horn L., Hsia J., Manson J.E., Stefanick M.L., Wassertheil-Smoller S., et al. Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA 295 (2006) 655-666
12. Davos C.H., Doehner W., Rauchhaus M., Cicoira M., Francis D.P., Coats A.J., et al. Body mass and survival in patients with chronic heart failure without cachexia: the importance of obesity. J. Card. Fail. 9 (2003) 29-35
13. Lavie C.J., Osman A.F., Milani R.V., and Mehra M.R. Body composition and prognosis in chronic systolic heart failure: the obesity paradox. Am. J. Cardiol. 91 (2003) 891-894
14. Curtis J.P., Selter J.G., Wang Y., Rathore S.S., Jovin I.S., Jadbabaie F., et al. The obesity paradox: body mass index and outcomes in patients with heart failure. Arch. Intern. Med. 165 (2005) 55-61
15. Gustafsson F., Kragelund C.B., Torp-Pedersen C., Seibaek M., Burchardt H., Akkan D., et al. Effect of obesity and being overweight on long-term mortality in congestive heart failure: influence of left ventricular systolic function. Eur. Heart J. 26 (2005) 58-64
16. Galal W., van Domburg R.T., Feringa H.H., Schouten O., Elhendy A., Bax J.J., et al. Relation of body mass index to outcome in patients with known or suspected coronary artery disease. Am. J. Cardiol. 99 (2007) 1485-1490
17. Morgan E.E., Rennison J.H., Young M.E., McElfresh T.A., Kung T.A., Tserng K.Y., et al. Effects of chronic activation of peroxisome proliferator-activated receptor-alpha or high-fat feeding in a rat infarct model of heart failure. Am. J. Physiol. Heart Circ. Physiol. 290 (2006) H1899-H1904
18. Rennison J.H., McElfresh T.A., Okere I.C., Vazquez E.J., Patel H.V., Foster A.B., et al. High-fat diet postinfarction enhances mitochondrial function and does not exacerbate left ventricular dysfunction. Am. J. Physiol. Heart Circ. Physiol. 292 (2007) H1498-H1506
19. Rennison J.H., McElfresh T.A., Okere I.C., Patel H.V., Foster A.B., Patel K.K., et al. Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure. Cardiovasc. Res. 79 (2008) 331-340
20. Okere I.C., Chandler M.P., McElfresh T.A., Rennison J.H., Kung T.A., Hoit B.D., et al. Carnitine palmitoyl transferase-I inhibition is not associated with cardiac hypertrophy in rats fed a high-fat diet. Clin. Exp. Pharmacol. Physiol. 34 (2007) 113-119
21. Chess D.J., Lei B., Hoit B.D., Azimzadeh A.M., and Stanley W.C. Effects of a high saturated fat diet on cardiac hypertrophy and dysfunction in response to pressure overload. J. Card. Fail. 14 (2008) 82-88
22. Okere I.C., Chess D.J., McElfresh T.A., Johnson J., Rennison J., Ernsberger P., et al. High-fat diet prevents cardiac hypertrophy and improves contractile function in the hypertensive Dahl salt-sensitive rat. Clin. Exp. Pharmacol. Physiol. 32 (2005) 825-831
23. Wilson C.R., Tran M.K., Salazar K.L., Young M.E., and Taegtmeyer H. Western diet, but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats. Biochem. J. 406 (2007) 457-467
24. Morgan E.E., Faulx M.D., McElfresh T.A., Kung T.A., Zawaneh M.S., Stanley W.C., et al. Validation of echocardiographic methods for assessing left ventricular dysfunction in rats with myocardial infarction. Am. J. Physiol. Heart Circ. Physiol. 287 (2004) H2049-H2053
25. Palmer J.W., Tandler B., and Hoppel C.L. Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle. J. Biol. Chem. 252 (1977) 8731-8739
26. Moghaddas S., Stoll M.S., Minkler P.E., Salomon R.G., Hoppel C.L., and Lesnefsky E.J. Preservation of cardiolipin content during aging in rat heart interfibrillar mitochondria. J. Gerontol. A. Biol. Sci. Med. Sci. 57 (2002) B22-B28
27. Tomec R.J., and Hoppel C.L. Carnitine palmitoyltransferase in bovine fetal heart mitochondria. Arch. Biochem. Biophys. 170 (1975) 716-723
28. Kerner J., Turkaly P.J., Minkler P.E., and Hoppel C.L. Aging skeletal muscle mitochondria in the rat: decreased uncoupling protein-3 content. Am. J. Physiol. Endocrinol. Metab. 281 (2001) E1054-E1062
29. Chance B., and Williams G.R. Respiratory enzymes in oxidative phosphorylation. I. Kinetics of oxygen utilization. J. Biol. Chem. 217 (1955) 383-393
30. Estabrook R. Mitochondrial respiratory control and polarographic measurement of ADP/O ratios. Methods in Enzymology. 10 ed. (1967) 41-47
31. Hoppel C., DiMarco J.P., and Tandler B. Riboflavin and rat hepatic cell structure and function. Mitochondrial oxidative metabolism in deficiency states. J. Biol. Chem. 254 (1979) 4164-4170
32. Srere P.A. Citrate synthase. Methods in Enzymology. 13 ed. (1969) 3-5
33. Panchal A.R., Stanley W.C., Kerner J., and Sabbah H.N. Beta-receptor blockade decreases carnitine palmitoyl transferase I activity in dogs with heart failure. J. Card. Fail. 4 (1998) 121-126
34. Lesnefsky E.J., and Hoppel C.L. Ischemia-reperfusion injury in the aged heart: role of mitochondria. Arch. Biochem. Biophys. 420 (2003) 287-297
35. Higa M., Zhou Y.T., Ravazzola M., Baetens D., Orci L., and Unger R.H. Troglitazone prevents mitochondrial alterations, beta cell destruction, and diabetes in obese prediabetic rats. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 11513-11518
36. Ouwens D.M., Boer C., Fodor M., de Galan P., Heine R.J., Maassen J.A., et al. Cardiac dysfunction induced by high-fat diet is associated with altered myocardial insulin signalling in rats. Diabetologia 48 (2005) 1229-1237
37. Young M.E., Guthrie P.H., Razeghi P., Leighton B., Abbasi S., Patil S., et al. Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart. Diabetes 51 (2002) 2587-2595
38. Murray A.J., Cole M.A., Lygate C.A., Carr C.A., Stuckey D.J., Little S.E., et al. Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart. J. Mol. Cell. Cardiol. 44 (2008) 694-700
39. Rosca M.G., Vazquez E.J., Kerner J., Parland W., Chandler M.P., Stanley W., et al. Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation. Cardiovasc. Res. 80 (2008) 30-39
40. Heather L.C., Cole M.A., Lygate C.A., Evans R.D., Stuckey D.J., Murray A.J., et al. Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart. Cardiovasc. Res. 72 (2006) 430-437
41. Sack M.N., Rader T.A., Park S., Bastin J., McCune S.A., and Kelly D.P. Fatty acid oxidation enzyme gene expression is downregulated in the failing heart. Circulation 94 (1996) 2837-2842
42. Sharma N., Okere I.C., Duda M.K., Johnson J., Yuan C.L., Chandler M.P., et al. High fructose diet increases mortality in hypertensive rats compared to a complex carbohydrate or high fat diet. Am. J. Hypertens. 20 (2007) 403-409
43. Chess D.J., Lei B., Hoit B.D., Azimzadeh A.M., and Stanley W.C. Deleterious effects of sugar and protective effects of starch on cardiac remodeling, contractile dysfunction, and mortality in response to pressure overload. Am. J. Physiol. Heart Circ. Physiol. 293 (2007) H1853-H1860
44. Sharma N., Okere I.C., Barrows B.R., Lei B., Duda M.K., Yuan C.L., et al. High-sugar diets increase cardiac dysfunction and mortality in hypertension compared to low-carbohydrate or high-starch diets. J. Hypertens. 26 (2008) 1402-1410
45. Chicco A.J., Sparagna G.C., McCune S.A., Johnson C.A., Murphy R.C., Bolden D.A., et al. Linoleate-rich high-fat diet decreases mortality in hypertensive heart failure rats compared with lard and low-fat diets. Hypertension 52 (2008) 549-555
46. Okere I.C., Chandler M.P., McElfresh T.A., Rennison J.H., Sharov V., Sabbah H.N., et al. Differential effects of saturated and unsaturated fatty acid diets on cardiomyocyte apoptosis, adipose distribution, and serum leptin. Am. J. Physiol. Heart Circ. Physiol. 291 (2006) H38-H44
47. American Heart Association. Heart disease and stroke statistics - 2008 update. 2008. Dallas, TX, American Heart Association.
48. Begriche K., Igoudjil A., Pessayre D., and Fromenty B. Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it. Mitochondrion 6 (2006) 1-28