-
1
-
-
0035124349
-
Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges
-
Attucci S., Carla V., Mannaioni G., Moroni F. Activation of type 5 metabotropic glutamate receptors enhances NMDA responses in mice cortical wedges. Br J Pharmacol 2001, 132:799-806.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 799-806
-
-
Attucci, S.1
Carla, V.2
Mannaioni, G.3
Moroni, F.4
-
2
-
-
0034332480
-
Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
-
Awad H., Hubert G.W., Smith Y., Levey A.I., Conn P.J. Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. J Neurosci 2000, 20:7871-7879.
-
(2000)
J Neurosci
, vol.20
, pp. 7871-7879
-
-
Awad, H.1
Hubert, G.W.2
Smith, Y.3
Levey, A.I.4
Conn, P.J.5
-
3
-
-
33751190762
-
Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests
-
Belozertseva I.V., Kos T., Popik P., Danysz W., Bespalov A.Y. Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests. Eur Neuropsychopharmacol 2007, 17:172-179.
-
(2007)
Eur Neuropsychopharmacol
, vol.17
, pp. 172-179
-
-
Belozertseva, I.V.1
Kos, T.2
Popik, P.3
Danysz, W.4
Bespalov, A.Y.5
-
4
-
-
31444441701
-
New approaches to antidepressant drug discovery: beyond monoamines
-
Berton O., Nestler E.J. New approaches to antidepressant drug discovery: beyond monoamines. Nat Rev Neurosci 2006, 7:137-151.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 137-151
-
-
Berton, O.1
Nestler, E.J.2
-
5
-
-
1642307557
-
Role of neurotrophic factors in the etiology and treatment of mood disorders
-
Duman R.S. Role of neurotrophic factors in the etiology and treatment of mood disorders. Neuromolecular Med 2004, 5:11-25.
-
(2004)
Neuromolecular Med
, vol.5
, pp. 11-25
-
-
Duman, R.S.1
-
6
-
-
33745208951
-
A neurotrophic model for stress-related mood disorders
-
Duman R.S., Monteggia L.M. A neurotrophic model for stress-related mood disorders. Biol Psychiatry 2006, 59:1116-1127.
-
(2006)
Biol Psychiatry
, vol.59
, pp. 1116-1127
-
-
Duman, R.S.1
Monteggia, L.M.2
-
7
-
-
70349122023
-
Vascular endothelial growth factor signaling is required for the behavioral actions of antidepressant treatment: pharmacological and cellular characterization
-
Greene J., Banasr M., Lee B., Warner-Schmidt J., Duman R.S. Vascular endothelial growth factor signaling is required for the behavioral actions of antidepressant treatment: pharmacological and cellular characterization. Neuropsychopharmacology 2009, 34:2459-2468.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 2459-2468
-
-
Greene, J.1
Banasr, M.2
Lee, B.3
Warner-Schmidt, J.4
Duman, R.S.5
-
8
-
-
59249102475
-
Remodeling of hippocampal spine synapses in the rat learned helplessness model of depression
-
Hajszan T., Dow A., Warner-Schmidt J.L., Szigeti-Buck K., Sallam N.L., Parducz A., Leranth C., Duman R.S. Remodeling of hippocampal spine synapses in the rat learned helplessness model of depression. Biol Psychiatry 2009, 65:392-400.
-
(2009)
Biol Psychiatry
, vol.65
, pp. 392-400
-
-
Hajszan, T.1
Dow, A.2
Warner-Schmidt, J.L.3
Szigeti-Buck, K.4
Sallam, N.L.5
Parducz, A.6
Leranth, C.7
Duman, R.S.8
-
9
-
-
0242653836
-
Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo
-
Heidbreder C.A., Bianchi M., Lacroix L.P., Faedo S., Perdona E., Remelli R., Cavanni P., Crespi F. Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo. Synapse 2003, 50:269-276.
-
(2003)
Synapse
, vol.50
, pp. 269-276
-
-
Heidbreder, C.A.1
Bianchi, M.2
Lacroix, L.P.3
Faedo, S.4
Perdona, E.5
Remelli, R.6
Cavanni, P.7
Crespi, F.8
-
10
-
-
0037831023
-
The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R)
-
Kessler R.C., Berglund P., Demler O., Jin R., Koretz D., Merikangas K.R., Rush A.J., Walters E.E., Wang P.S. The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003, 289:3095-3105.
-
(2003)
JAMA
, vol.289
, pp. 3095-3105
-
-
Kessler, R.C.1
Berglund, P.2
Demler, O.3
Jin, R.4
Koretz, D.5
Merikangas, K.R.6
Rush, A.J.7
Walters, E.E.8
Wang, P.S.9
-
11
-
-
33746351511
-
Effect of MPEP treatment on brain-derived neurotrophic factor gene expression
-
Legutko B., Szewczyk B., Pomierny-Chamiolo L., Nowak G., Pilc A. Effect of MPEP treatment on brain-derived neurotrophic factor gene expression. Pharmacol Rep 2006, 58:427-430.
-
(2006)
Pharmacol Rep
, vol.58
, pp. 427-430
-
-
Legutko, B.1
Szewczyk, B.2
Pomierny-Chamiolo, L.3
Nowak, G.4
Pilc, A.5
-
12
-
-
77955909841
-
MTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists
-
Li N., Lee B., Liu R.J., Banasr M., Dwyer J.M., Iwata M., Li X.Y., Aghajanian G., Duman R.S. mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science 2010, 329:959-964.
-
(2010)
Science
, vol.329
, pp. 959-964
-
-
Li, N.1
Lee, B.2
Liu, R.J.3
Banasr, M.4
Dwyer, J.M.5
Iwata, M.6
Li, X.Y.7
Aghajanian, G.8
Duman, R.S.9
-
13
-
-
33748999574
-
Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice
-
Li X., Need A.B., Baez M., Witkin J.M. Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice. J Pharmacol Exp Ther 2006, 319:254-259.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 254-259
-
-
Li, X.1
Need, A.B.2
Baez, M.3
Witkin, J.M.4
-
14
-
-
70349970566
-
The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders
-
Machado-Vieira R., Manji H.K., Zarate C.A. The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders. Neuroscientist 2009, 15:525-539.
-
(2009)
Neuroscientist
, vol.15
, pp. 525-539
-
-
Machado-Vieira, R.1
Manji, H.K.2
Zarate, C.A.3
-
15
-
-
0036212293
-
Molecular and cellular mechanisms underlying mood stabilization in bipolar disorder: implications for the development of improved therapeutics
-
Manji H.K., Zarate C.A. Molecular and cellular mechanisms underlying mood stabilization in bipolar disorder: implications for the development of improved therapeutics. Mol Psychiatry 2002, 7(Suppl. 1):S1-S7.
-
(2002)
Mol Psychiatry
, vol.7
, Issue.SUPPL. 1
-
-
Manji, H.K.1
Zarate, C.A.2
-
16
-
-
45549092746
-
Novel drugs and therapeutic targets for severe mood disorders
-
Mathew S.J., Manji H.K., Charney D.S. Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology 2008, 33:2080-2092.
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 2080-2092
-
-
Mathew, S.J.1
Manji, H.K.2
Charney, D.S.3
-
17
-
-
0037187646
-
Neurobiology of depression
-
Nestler E.J., Barrot M., DiLeone R.J., Eisch A.J., Gold S.J., Monteggia L.M. Neurobiology of depression. Neuron 2002, 34:13-25.
-
(2002)
Neuron
, vol.34
, pp. 13-25
-
-
Nestler, E.J.1
Barrot, M.2
DiLeone, R.J.3
Eisch, A.J.4
Gold, S.J.5
Monteggia, L.M.6
-
18
-
-
77957273984
-
Animal models of neuropsychiatric disorders
-
Nestler E.J., Hyman S.E. Animal models of neuropsychiatric disorders. Nat Neurosci 2010, 13:1161-1169.
-
(2010)
Nat Neurosci
, vol.13
, pp. 1161-1169
-
-
Nestler, E.J.1
Hyman, S.E.2
-
19
-
-
38949115944
-
Mood disorders: regulation by metabotropic glutamate receptors
-
Pilc A., Chaki S., Nowak G., Witkin J.M. Mood disorders: regulation by metabotropic glutamate receptors. Biochem Pharmacol 2008, 75:997-1006.
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 997-1006
-
-
Pilc, A.1
Chaki, S.2
Nowak, G.3
Witkin, J.M.4
-
20
-
-
0036669731
-
Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats
-
Pilc A., Klodzinska A., Branski P., Nowak G., Palucha A., Szewczyk B., Tatarczynska E., Chojnacka-Wojcik E., Wieronska J.M. Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats. Neuropharmacology 2002, 43:181-187.
-
(2002)
Neuropharmacology
, vol.43
, pp. 181-187
-
-
Pilc, A.1
Klodzinska, A.2
Branski, P.3
Nowak, G.4
Palucha, A.5
Szewczyk, B.6
Tatarczynska, E.7
Chojnacka-Wojcik, E.8
Wieronska, J.M.9
-
21
-
-
0018268297
-
Behavioural despair in rats: a new model sensitive to antidepressant treatments
-
Porsolt R.D., Anton G., Blavet N., Jalfre M. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur J Pharmacol 1978, 47:379-391.
-
(1978)
Eur J Pharmacol
, vol.47
, pp. 379-391
-
-
Porsolt, R.D.1
Anton, G.2
Blavet, N.3
Jalfre, M.4
-
22
-
-
42949123365
-
Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders
-
Sanacora G., Zarate C.A., Krystal J.H., Manji H.K. Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nat Rev Drug Discov 2008, 7:426-437.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 426-437
-
-
Sanacora, G.1
Zarate, C.A.2
Krystal, J.H.3
Manji, H.K.4
-
23
-
-
34548395111
-
The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior
-
Schmidt H.D., Duman R.S. The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behav Pharmacol 2007, 18:391-418.
-
(2007)
Behav Pharmacol
, vol.18
, pp. 391-418
-
-
Schmidt, H.D.1
Duman, R.S.2
-
24
-
-
0035069188
-
Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist
-
Tatarczynska E., Klodzinska A., Chojnacka-Wojcik E., Palucha A., Gasparini F., Kuhn R., Pilc A. Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist. Br J Pharmacol 2001, 132:1423-1430.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 1423-1430
-
-
Tatarczynska, E.1
Klodzinska, A.2
Chojnacka-Wojcik, E.3
Palucha, A.4
Gasparini, F.5
Kuhn, R.6
Pilc, A.7
-
25
-
-
0034861333
-
Glutamate release inhibiting properties of the novel mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP): complementary in vitro and in vivo evidence
-
Thomas L.S., Jane D.E., Gasparini F., Croucher M.J. Glutamate release inhibiting properties of the novel mGlu(5) receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP): complementary in vitro and in vivo evidence. Neuropharmacology 2001, 41:523-527.
-
(2001)
Neuropharmacology
, vol.41
, pp. 523-527
-
-
Thomas, L.S.1
Jane, D.E.2
Gasparini, F.3
Croucher, M.J.4
-
26
-
-
30044433660
-
Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice
-
Trivedi M.H., Rush A.J., Wisniewski S.R., Nierenberg A.A., Warden D., Ritz L., Norquist G., Howland R.H., Lebowitz B., McGrath P.J., Shores-Wilson K., Biggs M.M., Balasubramani G.K., Fava M. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice. Am J Psychiatry 2006, 163:28-40.
-
(2006)
Am J Psychiatry
, vol.163
, pp. 28-40
-
-
Trivedi, M.H.1
Rush, A.J.2
Wisniewski, S.R.3
Nierenberg, A.A.4
Warden, D.5
Ritz, L.6
Norquist, G.7
Howland, R.H.8
Lebowitz, B.9
McGrath, P.J.10
Shores-Wilson, K.11
Biggs, M.M.12
Balasubramani, G.K.13
Fava, M.14
-
27
-
-
0036386865
-
Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats
-
Wieronska J.M., Szewczyk B., Branski P., Palucha A., Pilc A. Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats. Amino Acids 2002, 23:213-216.
-
(2002)
Amino Acids
, vol.23
, pp. 213-216
-
-
Wieronska, J.M.1
Szewczyk, B.2
Branski, P.3
Palucha, A.4
Pilc, A.5
-
28
-
-
34247572536
-
Metabotropic glutamate receptors in the control of mood disorders
-
Witkin J.M., Marek G.J., Johnson B.G., Schoepp D.D. Metabotropic glutamate receptors in the control of mood disorders. CNS Neurol Disord Drug Targets 2007, 6:87-100.
-
(2007)
CNS Neurol Disord Drug Targets
, vol.6
, pp. 87-100
-
-
Witkin, J.M.1
Marek, G.J.2
Johnson, B.G.3
Schoepp, D.D.4
-
29
-
-
0042126365
-
Modulators of the glutamatergic system: implications for the development of improved therapeutics in mood disorders
-
Zarate C.A., Quiroz J., Payne J., Manji H.K. Modulators of the glutamatergic system: implications for the development of improved therapeutics in mood disorders. Psychopharmacol Bull 2002, 36:35-83.
-
(2002)
Psychopharmacol Bull
, vol.36
, pp. 35-83
-
-
Zarate, C.A.1
Quiroz, J.2
Payne, J.3
Manji, H.K.4
-
30
-
-
69349091136
-
Isolation rearing induces social and emotional function abnormalities and alters glutamate and neurodevelopment-related gene expression in rats
-
Zhao X., Sun L., Jia H., Meng Q., Wu S., Li N., He S. Isolation rearing induces social and emotional function abnormalities and alters glutamate and neurodevelopment-related gene expression in rats. Prog Neuropsychopharmacol Biol Psychiatry 2009, 33:1173-1177.
-
(2009)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.33
, pp. 1173-1177
-
-
Zhao, X.1
Sun, L.2
Jia, H.3
Meng, Q.4
Wu, S.5
Li, N.6
He, S.7
|