Isolation rearing induces social and emotional function abnormalities and alters glutamate and neurodevelopment-related gene expression in rats

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 33, Issue 7, 2009, Pages 1173-1177

  Zhao, Xiaohong ^a   Sun, Lei ^a,c   Jia, Hongxiao ^b   Meng, Qingxuan ^c   Wu, Si ^c   Li, Nanxin ^c,d,e   He, Shuchang ^c  

^a BEIJING UNION UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c PEKING UNIVERSITY   (China)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e YALE UNIVERSITY   (United States)

Author keywords

Anxiety; Glutamate; Neurodevelopmental related gene; Social isolation; Social recognition

Indexed keywords

GLUTAMIC ACID; MEMBRANE PROTEIN; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; POSTSYNAPTIC DENSITY PROTEIN 95; SYNAPSE ASSOCIATED PROTEIN 102; UNCLASSIFIED DRUG;

AGGRESSION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EMOTIONALITY; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HYPERACTIVITY; MALE; MAZE TEST; NONHUMAN; OPEN FIELD TEST; PREFRONTAL CORTEX; RAT; SOCIAL BEHAVIOR; SOCIAL DISABILITY; SOCIAL ISOLATION;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; EXPLORATORY BEHAVIOR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUTAMIC ACID; HIPPOCAMPUS; HYPERKINESIS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MAZE LEARNING; MEMBRANE PROTEINS; MOOD DISORDERS; NEUROPEPTIDES; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SOCIAL ISOLATION;

EID: 69349091136     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2009.06.016     Document Type: Article

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