Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCL4-induced acute liver injury

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 303, Issue 5, 2012, Pages

  Zahedi, Kamyar ^a   Barone, Sharon L ^a   Xu, Jie ^a   Steinberg, Nora ^b   Schuster, Rebecca ^a   Lentsch, Alex B ^a   Amlal, Hassane ^a   Wang, Jiang ^c   Casero, Robert A ^b   Soleimani, Manoocher ^a,d  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c Department of Pathology and Laboratory Medicine ^*  (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Carbon tetrachloride; Hepatotoxicity; Polyamine

Indexed keywords

ALANINE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CASPASE 3; CYTOCHROME P450 2E1; POLYAMINE OXIDASE; PROTEIN NOXA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME INHIBITION; GENE; GENE ACTIVITY; GENE EXPRESSION; GENOTYPE; KNOCKOUT MOUSE; LIPID PEROXIDATION; LIVER CELL; LIVER INJURY; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPERMINE SPERMIDINE N1 ACETYLTRANSFERASE GENE; WILD TYPE;

EID: 84865741143     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00431.2011     Document Type: Article

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