Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle cerebral artery occlusion

Journal of Neurochemistry

Volumn 72, Issue 2, 1999, Pages 765-770

  Doǧan, Aclan ^b   Rao, A Muralikrishna ^b   Hatcher, James ^b   Rao, V L Raghavendra ^b   Başkaya, Mustafa K ^a   Dempsey, Robert J ^b  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Cerebral edema; Cerebral ischemia; MDL 72527; Polyamine; Polyamine interconversion pathway; Polyamine oxidase

Indexed keywords

ENZYME INHIBITOR; N,N' BIS(2,3 BUTADIENYL)PUTRESCINE; POLYAMINE; POLYAMINE OXIDASE; POLYAMINE OXIDASE INHIBITOR; PUTRESCINE; SPERMIDINE; SPERMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN EDEMA; BRAIN ISCHEMIA; BRAIN SIZE; CONTROLLED STUDY; DRUG EFFECT; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SPONTANEOUSLY HYPERTENSIVE RAT;

ANIMALS; ARTERIAL OCCLUSIVE DISEASES; BLOOD GAS ANALYSIS; BLOOD PRESSURE; BODY TEMPERATURE; BRAIN; BRAIN EDEMA; BRAIN ISCHEMIA; CEREBROVASCULAR CIRCULATION; INJECTIONS, INTRAPERITONEAL; MALE; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; POLYAMINES; PUTRESCINE; RATS; RATS, INBRED SHR; WATER;

EID: 0345291173     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0720765.x     Document Type: Article

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