Activation and crosstalk between the endoplasmic reticulum road and JNK pathway in ischemia-reperfusion brain injury

Acta Neurochirurgica

Volumn 154, Issue 7, 2012, Pages 1197-1203

  Zhu, Haiying ^a,b   Zhu, Haiyan ^a   Xiao, Shuping ^a   Sun, Hongyu ^a   Xie, Chunli ^a   Ma, Yingwen ^a  

^a Affiliated Hospital of Taian Medical College   (China)

^b People's Hospital of Daqing   (China)

Author keywords

Brain; C Jun N terminal kinase; Caspase 12; Endoplasmic reticulum stress; GADD153; Ischemia reperfusion

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 12; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE ASSOCIATION; DOUBLE LABEL IMMUNOFLUORESCENCE STAINING; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GLIA CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOLECULAR INTERACTION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRAIN; CASPASE 12; CORPUS STRIATUM; ENDOPLASMIC RETICULUM; FRONTAL LOBE; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MAP KINASE KINASE 4; MICROSCOPY, FLUORESCENCE; PARIETAL LOBE; RATS; RATS, WISTAR; REPERFUSION INJURY; TRANSCRIPTION FACTOR CHOP;

EID: 84865725209     PISSN: 00016268     EISSN: 09420940     Source Type: Journal    
DOI: 10.1007/s00701-012-1396-z     Document Type: Article

References (30)

1. Belayev L, Alonso OF, Busto R, Zhao W, Ginsberg MD (1996) Middle cerebral artery occlusion in the rat by intraluminal suture. Stroke 27:1616-1623
2. Boyce M, Yuan J (2006) Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ 13:363-373
3. Elihinda AA, Tirasophon W, Kaufman RJ (1999) The cellular response to protein misfolding in the endoplasmic reticulum. Gene Expr 7:293-300 (Pubitemid 29372073)
4. Ferri KF, Kroemer G (2001) Organelle-specific initiation of cell death pathways. Nat Cell Biol 3:255-263
5. Kogler H, Schott P, Toischer K, Milting H, Van PN, Kohlhaas M, Grebe C, Kassner A, Domeier E, Teucher N, Seidler T, Knöll R, Maier LS, El-Banayosy A, Körfer R, Hasenfuss G (2006) Relevance of brain naturetic peptide in preload-dependent regulation of cardiac sarcoplasmic reticuIum Ca2+ ATPase expression. Circulation l13:2724-2732 (Pubitemid 43947990)
6. Li G, Mongillo M, Chin KT, Harding H, Ron D, Marks AR, Tabas I (2009) Role of ERO1-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis. J Cell Biol 186:783-792
7. Lindholm D, Wootz H, Korhonen L (2006) ER stress and neurodegenerative diseases. Cell Death Differ 13:385-392
8. Lin JH, Li H, Yasumura D, Cohen HR, Zhang C, Panning B, Shokat KM, LaVail MM, Walter P (2007) IRE1 signaling affects cell fate during the unfolded protein response. Science 318:944- 949 (Pubitemid 350098984)
9. Longa EZ, Weinstein PR, Carlson S, Cummins R (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20:84-91 (Pubitemid 19040218)
10. Mary V, Wahl F, Uzan A, Stutzmann J-M (2001) Enoxaparin in experimental stroke neuroprotection and therapeutic window of opportunity. Stroke 32:993-999 (Pubitemid 32285173)
11. Melani A, Pantoni L, Corsi C, Bianchi L, Monopoli A, Bertorelli R, Pepeu G, Pedata F (1999) Striatal outflow of adenosine, excitatory amino acids, gamma- aminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion: correlations with neurological deficit and histopathological damage. Stroke 30:2448-2454
12. Mokudai T, Ayoub IA, SakakibaraY LE-J, Ogilvy CS, Maynard KI, Maiese K (2000) Delayed treatment with nicotinamide (vitamin b3) improves neurological outcome and reduces infarct volume after transient focal cerebral ischemia in wistar rats. Stroke 31:1679-1685
13. Mori K (2000) Triparite management of unfolded protein in the endoplasmin reticulum. Cell 101:451-454
14. Nakagawa T, Zhu H, Morishima N, Li E, Xu J, Yankner BA, Yuan J (2000) Caspase-12 mediates ER-specific apoptosis and cytotoxicity by amyloid ß. Nature 403:98-103 (Pubitemid 30038529)
15. Nakka VP, Gusain A, Raghubir R (2010) Endoplasmic reticulum stress plays critical role in brain damage after cerebral ischemia/ reperfusion in rats. Neurotox Res 17:189-202
16. Nickischer D, Laethem C, Trask OJ, Williams RG, Kandasamy R, Johnston PA (2006) Development and implementation of three mitogen-activated protein kinase (MAPK) signaling pathway imaging assays to provide MAPK module selectivity profiling for kinase inhibitors: MK2-EGFP translocation, c-Jun, and ERK activation. Methods Enzym 414:389-418 (Pubitemid 44716234)
17. Noguchi K, Kitanaka C, Yamana H, Kokubu A, Mochizuki T, Kuchino Y (1999) Regulation of c-Myc through phosphory lation at Set-62 and Set-71 by c-Jun N-terminal kinase. J Biol Chem 274:32580-32587
18. Oyadomari S, Mori M (2004) Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 11:381-389 (Pubitemid 38489416)
19. Paschen W, Doutheil J (1999) Disturbances of the functioning of endoplasmic reticulum. A key mechanism underlying neuronal injury. J Cereb Blood Flow Metab 19:1-18 (Pubitemid 29283575)
20. Paxinos G, Watson C, Pennisi M, Topple A (1985) Bregma, lambda and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight. J Neurosci Methods 13:139-143 (Pubitemid 15008633)
21. Rosenberg GA, Estrada EY, Dencoff JE (1998) Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain. Stroke 29:2189-2195 (Pubitemid 28443538)
22. ShibataM, Hattori H, Sasaki T, Gotoh J,Hamada J, FukuuchiY (2003) Activation of caspase-12 by endoplasmic reticulum stress induced by transient middle cerebral artery occlusion in mice. Neuroscience 118:491-499 (Pubitemid 36423263)
23. Suginol T, Nozakil K, Takagil Y, Hattori I, Hashimoto N, Moriguchi T, Nishida E (2000) Activation of mitogen-activated protein kinases after transient forebrain ischemia in gerbil hippocampus. J Neurosci 20:4506-4514 (Pubitemid 30396616)
24. Takagi Y, Nozaki K, Sugino T, Hattori I, Hashimoto N (2000) Phosphorylation of c-Jun-NH(2)-terminal kinase and p38 mitogenactivated protein kinase after transient forebrain ischemia in mice. Neurosci Lett 294:117-120
25. Takuji T, Nishida E (2002) Docking interactions in the mitogenactivated protein kinase cascades. Pharmacol Ther 93:193-202 (Pubitemid 34615560)
26. Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J, Backs T, Bassel-Duby R, Olson EN, Anderson ME, Tabas I (2009) Calcium/calmodulin- dependent protein kinase II links endoplasmic reticulum stress with Fas and mitochondrial apoptosis pathways. J Clin Invest 119:2925-2941
27. Verkhratsky A (2005) Physiology and pathophysiology of the calcium store in the endoplasmic reticulum of neurons. Physiol Rev 85:201-279 (Pubitemid 40173995)
28. Wu J, Kaufman RJ (2006) From acute ER stress to physiological roles of the unfolded protein response. Cell Death Differ 13:374- 384
29. Yao H, Gao J, Feng YB, Pang ZY, Chi ZF (2007) 2R, 4R-APDC decreases cell proliferation in the dentate gyrus of adult rats: the effect of 2R, 4R-APDC on cell proliferation. Neuroreport 18:1459-62 (Pubitemid 47295945)
30. Zhang H, Song LC, Liu YY, Ma Y, Lu YL (2007) Pinacidil reduces neuronal apoptosis following cerebral ischemia-reperfusion in rats through both mitochondrial and death-receptor signal pathways. Neurosci Bul 23:145-150 (Pubitemid 47104868)