Functional genomics-and network-driven systems biology approaches for pharmacogenomics and toxicogenomics

Current Drug Metabolism

Volumn 13, Issue 7, 2012, Pages 952-967

  Yang, Xia ^a,b   Zhang, Bin ^b,c   Zhu, Jun ^b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SageBionotworks   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Drug response; Functional genomics; Genome wide association study; Molecular network; Pharmacogenomics; Single nucleotide polymorphism; Systems biology; Toxicogenomics

Indexed keywords

ACENOCOUMAROL; ANTIDEPRESSANT AGENT; ASPARAGINASE; BETA INTERFERON; CHLORAMBUCIL; CITALOPRAM; CLOPIDOGREL; CYCLOPHOSPHAMIDE; DAUNORUBICIN; ENZYME; FLUCLOXACILLIN; FLUDARABINE; HEPATITIS B VACCINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ILOPERIDONE; LITHIUM; LUMIRACOXIB; METFORMIN; METHOTREXATE; NEUROLEPTIC AGENT; PARACETAMOL; PEGINTERFERON ALPHA2A PLUS RIBAVIRIN; PEGINTERFERON ALPHA2B PLUS RIBAVIRIN; PLATINUM DERIVATIVE; PREDNISONE; THIAZIDE DIURETIC AGENT; TUMOR NECROSIS FACTOR ANTIBODY; UNINDEXED DRUG; VINCRISTINE; WARFARIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; BIPOLAR DISORDER; BLOOD CLOTTING DISORDER; CHRONIC LYMPHATIC LEUKEMIA; DEPRESSION; DRUG EFFICACY; DRUG METABOLISM; DYSLIPIDEMIA; ENZYME ACTIVITY; FUNCTIONAL GENOMICS; GENE EXPRESSION; GENE LOCUS; GENE TECHNOLOGY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HEPATITIS B; HEPATITIS C; HUMAN; HYPERTENSION; INFECTION; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; MAJOR DEPRESSION; MULTIPLE SCLEROSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; OSTEOARTHRITIS; PAIN; PERSONALIZED MEDICINE; PHARMACOGENOMICS; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SCHIZOPHRENIA; SYSTEMS BIOLOGY; TOXICITY TESTING; TOXICOGENETICS;

ANIMALS; GENE REGULATORY NETWORKS; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HUMANS; PHARMACOGENETICS; SYSTEMS BIOLOGY; TOXICOGENETICS;

EID: 84865711042     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/138920012802138633     Document Type: Article

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