-
2
-
-
0037029424
-
Multiple sclerosis
-
DOI 10.1016/S0140-6736(02)08220-X
-
Compston A, Coles A. Multiple sclerosis. Lancet 2002; 359: 1221-1231. (Pubitemid 34304266)
-
(2002)
Lancet
, vol.359
, Issue.9313
, pp. 1221-1231
-
-
Compston, A.1
Coles, A.2
-
3
-
-
0024504359
-
The natural history of multiple sclerosis: A geographically based study. I. Clinical course and disability
-
Weinshenker BG, Bass B, Rice GP, Noseworthy J, Carriere W, Baskerville J et al. The natural history of multiple sclerosis: a geographically based study. I. Clinical course and disability. Brain 1989; 112(Part 1): 133-146. (Pubitemid 19056478)
-
(1989)
Brain
, vol.112
, Issue.1
, pp. 133-146
-
-
Weinshenker, B.G.1
Bass, B.2
Rice, G.P.A.3
Noseworthy, J.4
Carriere, W.5
Baskerville, J.6
Ebers, G.C.7
-
4
-
-
17644396349
-
Immunology of multiple sclerosis
-
DOI 10.1146/annurev.immunol.23.021704.115707
-
Sospedra M, Martin R. Immunology of multiple sclerosis. Annu Rev Immunol 2005; 23: 683-747. (Pubitemid 40563183)
-
(2005)
Annual Review of Immunology
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
5
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomewide study
-
DOI 10.1056/NEJMoa073493
-
Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, de Jager PL et al. Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med 2007; 357: 851-862. (Pubitemid 47347319)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.9
, pp. 851-862
-
-
Hafler, D.A.1
Compston, A.2
Sawcer, S.3
Lander, E.S.4
Daly, M.J.5
De Jager, P.L.6
De Bakker, P.I.W.7
Gabriel, S.B.8
Mirel, D.B.9
Ivinson, A.J.10
Pericak-Vance, M.A.11
Gregory, S.G.12
Rioux, J.D.13
McCauley, J.L.14
Haines, J.L.15
Barcellos, L.F.16
Cree, B.17
Oksenberg, J.R.18
Hauser, S.L.19
-
6
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
-
de Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet 2009; 41: 776-782.
-
(2009)
Nat Genet
, vol.41
, pp. 776-782
-
-
De Jager, P.L.1
Jia, X.2
Wang, J.3
De Bakker, P.I.4
Ottoboni, L.5
Aggarwal, N.T.6
-
7
-
-
45549092100
-
The genetics of multiple sclerosis: SNPs to pathways to pathogenesis
-
DOI 10.1038/nrg2395, PII NRG2395
-
Oksenberg JR, Baranzini SE, Sawcer S, Hauser SL. The genetics of multiple sclerosis: SNPs to pathways to pathogenesis. Nat Rev Genet 2008; 9: 516-526. (Pubitemid 351861542)
-
(2008)
Nature Reviews Genetics
, vol.9
, Issue.7
, pp. 516-526
-
-
Oksenberg, J.R.1
Baranzini, S.E.2
Sawcer, S.3
Hauser, S.L.4
-
8
-
-
33645324079
-
Drug insight: Interferon treatment in multiple sclerosis
-
Ann MR, Rudick RA. Drug insight: interferon treatment in multiple sclerosis. Nat Clin Pract Neurol 2006; 2: 34-44.
-
(2006)
Nat Clin Pract Neurol
, vol.2
, pp. 34-44
-
-
Ann, M.R.1
Rudick, R.A.2
-
9
-
-
3242877381
-
Immunogenicity of interferon beta: Differences among products
-
Bertolotto A, Deisenhammer F, Gallo P, Solberg SP. Immunogenicity of interferon beta: differences among products. J Neurol 2004; 251(Suppl 2): II15-II24: II15-II24.
-
(2004)
J Neurol
, vol.251
, Issue.SUPPL. 2
-
-
Bertolotto, A.1
Deisenhammer, F.2
Gallo, P.3
Solberg, S.P.4
-
10
-
-
20444470178
-
Immune response to immunotherapy: The role of neutralising antibodies to interferon beta in the treatment of multiple sclerosis
-
DOI 10.1016/S1474-4422(05)70117-4, PII S1474442205701174
-
Hemmer B, Stuve O, Kieseier B, Schellekens H, Hartung HP. Immune response to immunotherapy: the role of neutralising antibodies to interferon beta in the treatment of multiple sclerosis. Lancet Neurol 2005; 4: 403-412. (Pubitemid 40826532)
-
(2005)
Lancet Neurology
, vol.4
, Issue.7
, pp. 403-412
-
-
Hemmer, B.1
Stuve, O.2
Kieseier, B.3
Schellekens, H.4
Hartung, H.-P.5
-
11
-
-
34250632789
-
Measuring and management of anti-interferon beta antibodies in subjects with multiple sclerosis
-
DOI 10.1177/1352458506073522
-
Farrell RA, Giovannoni G. Measuring and management of antiinterferon beta antibodies in subjects with multiple sclerosis. Mult Scler 2007; 13: 567-577. (Pubitemid 46939521)
-
(2007)
Multiple Sclerosis
, vol.13
, Issue.5
, pp. 567-577
-
-
Farrell, R.A.1
Giovannoni, G.2
-
12
-
-
68249162126
-
Absence of MxA induction by interferon beta in patients with MS reflects complete loss of bioactivity
-
Hesse D, Sellebjerg F, Sorensen PS. Absence of MxA induction by interferon beta in patients with MS reflects complete loss of bioactivity. Neurology 2009; 73: 372-377.
-
(2009)
Neurology
, vol.73
, pp. 372-377
-
-
Hesse, D.1
Sellebjerg, F.2
Sorensen, P.S.3
-
13
-
-
0005489101
-
Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: Experience during the first three years
-
The IFNB Multiple Sclerosis Study Group and the University of British Columbia MS/MRI Analysis Group
-
The IFNB Multiple Sclerosis Study Group and the University of British Columbia MS/MRI Analysis Group. Neutralizing antibodies during treatment of multiple sclerosis with interferon beta-1b: experience during the first three years. Neurology 1996; 47: 889-894.
-
(1996)
Neurology
, vol.47
, pp. 889-894
-
-
-
14
-
-
10744225329
-
Clinical importance of neutralising antibodies against interferon beta in patients with relapsing-remitting multiple sclerosis
-
DOI 10.1016/S0140-6736(03)14541-2
-
Sorensen PS, Ross C, Clemmesen KM, Bendtzen K, Frederiksen JL, Jensen K et al. Clinical importance of neutralising antibodies against interferon beta in patients with relapsing-remitting multiple sclerosis. Lancet 2003; 362: 1184-1191. (Pubitemid 37255344)
-
(2003)
Lancet
, vol.362
, Issue.9391
, pp. 1184-1191
-
-
Sorensen, P.S.1
Ross, C.2
Clemmesen, K.M.3
Bendtzen, K.4
Frederiksen, J.L.5
Jensen, K.6
Kristensen, O.7
Petersen, T.8
Rasmussen, S.9
Ravnborg, M.10
Stenager, E.11
Koch-Henriksen, N.12
-
15
-
-
22044450811
-
Neutralizing antibodies and efficacy of interferon beta-1a: A 4-year controlled study
-
DOI 10.1212/01.wnl.0000171747.59767.5c
-
Kappos L, Clanet M, Sandberg-Wollheim M, Radue EW, Hartung HP, Hohlfeld R et al. Neutralizing antibodies and efficacy of interferon beta-1a: a 4-year controlled study. Neurology 2005; 65: 40-47. (Pubitemid 40967774)
-
(2005)
Neurology
, vol.65
, Issue.1
, pp. 40-47
-
-
Kappos, L.1
Clanet, M.2
Sandberg-Wollheim, M.3
Radue, E.W.4
Hartung, H.P.5
Hohlfeld, R.6
Xu, J.7
Bennett, D.8
Sandrock, A.9
Goelz, S.10
-
16
-
-
22044436956
-
Interferon beta-1a in MS: Results following development of neutralizing antibodies in PRISMS
-
DOI 10.1212/01.wnl.0000171748.48188.5b
-
Francis GS, Rice GP, Alsop JC. Interferon beta-1a in MS: results following development of neutralizing antibodies in PRISMS. Neurology 2005; 65: 48-55. (Pubitemid 40967775)
-
(2005)
Neurology
, vol.65
, Issue.1
, pp. 48-55
-
-
Francis, G.S.1
Rice, G.P.A.2
Alsop, J.C.3
-
17
-
-
27744509228
-
Guidelines on use of anti-IFN-beta antibody measurements in multiple sclerosis: Report of an EFNS Task Force on IFN-beta antibodies in multiple sclerosis
-
DOI 10.1111/j.1468-1331.2005.01386.x
-
Sorensen PS, Deisenhammer F, Duda P, Hohlfeld R, Myhr KM, Palace J et al. Guidelines on use of anti-IFN-beta antibody measurements in multiple sclerosis: report of an EFNS task force on IFN-beta antibodies in multiple sclerosis. Eur J Neurol 2005; 12: 817-827. (Pubitemid 41597593)
-
(2005)
European Journal of Neurology
, vol.12
, Issue.11
, pp. 817-827
-
-
Sorensen, P.S.1
Deisenhammer, F.2
Duda, P.3
Hohlfeld, R.4
Myhr, K.-M.5
Palace, J.6
Polman, C.7
Pozzilli, C.8
Ross, C.9
-
18
-
-
34147161297
-
Neutralizing antibodies to interferon beta: Assessment of their clinical and radiographic impact: An evidence report: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
-
DOI 10.1212/01.wnl.0000258545.73854.cf, PII 0000611420070327000006
-
Goodin DS, Frohman EM, Hurwitz B, O'Connor PW, Oger JJ, Reder AT et al. Neutralizing antibodies to interferon beta: assessment of their clinical and radiographic impact: an evidence report: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2007; 68: 977-984. (Pubitemid 46569129)
-
(2007)
Neurology
, vol.68
, Issue.13
, pp. 977-984
-
-
Goodin, D.S.1
Frohman, E.M.2
Hurwitz, B.3
O'Connor, P.W.4
Oger, J.J.5
Reder, A.T.6
Stevens, J.C.7
-
19
-
-
77953454473
-
Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis
-
Polman CH, Bertolotto A, Deisenhammer F, Giovannoni G, Hartung HP, Hemmer B et al. Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis. Lancet Neurol 2010; 9: 740-750.
-
(2010)
Lancet Neurol
, vol.9
, pp. 740-750
-
-
Polman, C.H.1
Bertolotto, A.2
Deisenhammer, F.3
Giovannoni, G.4
Hartung, H.P.5
Hemmer, B.6
-
20
-
-
48349093740
-
HLA-DRB1*0401 and HLA-DRB1*0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis
-
Hoffmann S, Cepok S, Grummel V, Lehmann-Horn K, Hackermuller J, Stadler PF et al. HLA-DRB1*0401 and HLA-DRB1*0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis. Am J Hum Genet 2008; 83: 219-227.
-
(2008)
Am J Hum Genet
, vol.83
, pp. 219-227
-
-
Hoffmann, S.1
Cepok, S.2
Grummel, V.3
Lehmann-Horn, K.4
Hackermuller, J.5
Stadler, P.F.6
-
21
-
-
0242489120
-
An improved ELISA for screening for neutralizing anti-IFN-beta antibodies in MS patients
-
Pachner AR. An improved ELISA for screening for neutralizing anti-IFNbeta antibodies in MS patients. Neurology 2003; 61: 1444-1446. (Pubitemid 37463391)
-
(2003)
Neurology
, vol.61
, Issue.10
, pp. 1444-1446
-
-
Pachner, A.R.1
-
22
-
-
0242333124
-
MxA Gene Expression Analysis as an Interferon-beta Bioactivity Measurement in Patients with Multiple Sclerosis and the Identification of Antibody-Mediated Decreased Bioactivity
-
DOI 10.2165/00066982-200307010-00004
-
Pachner A, Narayan K, Price N, Hurd M, Dail D. MxA gene expression analysis as an interferon-beta bioactivity measurement in patients with multiple sclerosis and the identification of antibody-mediated decreased bioactivity. Mol Diagn 2003; 7: 17-25. (Pubitemid 37339029)
-
(2002)
Molecular Diagnosis
, vol.7
, Issue.1
, pp. 17-25
-
-
Pachner, A.R.1
Narayan, K.2
Price, N.3
Hurd, M.4
Dail, D.5
-
23
-
-
66249136346
-
Neutralizing antibodies to interferon-beta and other immunological treatments for multiple sclerosis: Prevalence and impact on outcomes
-
Deisenhammer F. Neutralizing antibodies to interferon-beta and other immunological treatments for multiple sclerosis: prevalence and impact on outcomes. CNS Drugs 2009; 23: 379-396.
-
(2009)
CNS Drugs
, vol.23
, pp. 379-396
-
-
Deisenhammer, F.1
-
24
-
-
0037180479
-
Randomized, comparative study of interferon beta-1a treatment regimens in MS: The evidence trial
-
Panitch H, Goodin DS, Francis G, Chang P, Coyle PK, O'Connor P et al. Randomized, comparative study of interferon beta-1a treatment regimens in MS: the EVIDENCE Trial. Neurology 2002; 59: 1496-1506. (Pubitemid 35387053)
-
(2002)
Neurology
, vol.59
, Issue.10
, pp. 1496-1506
-
-
Panitch, H.1
Goodin, D.S.2
Francis, G.3
Chang, P.4
Coyle, P.K.5
O'Connor, P.6
Monaghan, E.7
Li, D.8
Weinshenker, B.9
-
25
-
-
0037181634
-
Every-other-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis: Results of a 2-year prospective randomised multicentre study (INCOMIN)
-
DOI 10.1016/S0140-6736(02)08430-1
-
Durelli L, Verdun E, Barbero P, Bergui M, Versino E, Ghezzi A et al. Everyother-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis: results of a 2-year prospective randomised multicentre study (INCOMIN). Lancet 2002; 359: 1453-1460. (Pubitemid 34457761)
-
(2002)
Lancet
, vol.359
, Issue.9316
, pp. 1453-1460
-
-
Durelli, L.1
Verdun, E.2
Barbero, P.3
Bergui, M.4
Versino, E.5
Ghezzi, A.6
Montanari, E.7
Zaffaroni, M.8
-
26
-
-
77950876430
-
Clinical effect of neutralizing antibodies to interferon beta that persist long after cessation of therapy for multiple sclerosis
-
van der Voort LF, Gilli F, Bertolotto A, Knol DL, Uitdehaag BM, Polman CH et al. Clinical effect of neutralizing antibodies to interferon beta that persist long after cessation of therapy for multiple sclerosis. Arch Neurol 2010; 67: 402-407.
-
(2010)
Arch Neurol
, vol.67
, pp. 402-407
-
-
Van Der Voort, L.F.1
Gilli, F.2
Bertolotto, A.3
Knol, D.L.4
Uitdehaag, B.M.5
Polman, C.H.6
-
27
-
-
37249047361
-
Focal adhesion kinase as a regulator of cell tension in the progression of cancer
-
DOI 10.1016/j.semcancer.2007.08.002, PII S1044579X07000727
-
Tilghman RW, Parsons JT. Focal adhesion kinase as a regulator of cell tension in the progression of cancer. Semin Cancer Biol 2008; 18: 45-52. (Pubitemid 350266368)
-
(2008)
Seminars in Cancer Biology
, vol.18
, Issue.1
, pp. 45-52
-
-
Tilghman, R.W.1
Parsons, J.T.2
-
28
-
-
55449112185
-
Genome-wide associations of gene expression variation in humans
-
Stranger BE, Forrest MS, Clark AG, Minichiello MJ, Deutsch S, Lyle R et al. Genome-wide associations of gene expression variation in humans. PLoS Genet 2005; 1: e78.
-
(2005)
PLoS Genet
, vol.1
-
-
Stranger, B.E.1
Forrest, M.S.2
Clark, A.G.3
Minichiello, M.J.4
Deutsch, S.5
Lyle, R.6
-
29
-
-
57249114505
-
SNAP: A web-based tool for identification and annotation of proxy SNPs using HapMap
-
Johnson AD, Handsaker RE, Pulit S, Nizzari MM, O'Donnell CJ, de Bakker PIW. SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap. Bioinformatics 2008; 24: 2938-2939.
-
(2008)
Bioinformatics
, vol.24
, pp. 2938-2939
-
-
Johnson, A.D.1
Handsaker, R.E.2
Pulit, S.3
Nizzari, M.M.4
O'Donnell, C.J.5
De Bakker, P.I.W.6
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