메뉴 건너뛰기




Volumn 72, Issue 3, 2012, Pages 789-818

Analytical results for a multistate gene model

Author keywords

Analytical distribution; Master equation; Noise; Promoter progress

Indexed keywords

ANALYTICAL DISTRIBUTION; ANALYTICAL EXPRESSIONS; ANALYTICAL RESULTS; BIOLOGICAL PHENOMENA; FANO FACTOR; GENE MODEL; MASTER EQUATIONS; MULTI-STATE; MULTISTEP PROCESS; NOISE; NOISE INTENSITIES; PROMOTER PROGRESS; SLOW DYNAMICS; STOCHASTIC TRANSITIONS; TWO STAGE MODEL; WAITING TIME DISTRIBUTIONS;

EID: 84865697158     PISSN: 00361399     EISSN: None     Source Type: Journal    
DOI: 10.1137/110852887     Document Type: Article
Times cited : (92)

References (71)
  • 1
    • 0242416539 scopus 로고    scopus 로고
    • Noise in eukaryotic gene expression
    • DOI 10.1038/nature01546
    • W. J. Blake, M. Kærn, C. R. Cantor, and J. J. Collins, Noise in eukaryotic gene expression, Nature, 422 (2003), pp. 633-637. (Pubitemid 36460419)
    • (2003) Nature , vol.422 , Issue.6932 , pp. 633-637
    • Blake, W.J.1    Kaern, M.2    Cantor, C.R.3    Collins, J.J.4
  • 2
    • 2942718723 scopus 로고    scopus 로고
    • Control of stochasticity in eukaryotic gene expression
    • J. Raser and E. O'Shea, Control of stochasticity in eukaryotic gene expression, Science, 304 (2003), pp. 1811-1814.
    • (2003) Science , vol.304 , pp. 1811-1814
    • Raser, J.1    O'Shea, E.2
  • 3
    • 43049157587 scopus 로고    scopus 로고
    • Nucleosome retention and the stochastic nature of promoter chromatin remodeling for transcription
    • DOI 10.1016/j.cell.2008.02.051, PII S0092867408004455
    • H. Boeger, J. Griesenbeck, and R. D. Kornberg, Nucleosome retention and the stochastic nature of promoter chromatin remodeling for transcription, Cell, 133 (2008), pp. 716-726. (Pubitemid 351636300)
    • (2008) Cell , vol.133 , Issue.4 , pp. 716-726
    • Boeger, H.1    Griesenbeck, J.2    Kornberg, R.D.3
  • 4
    • 82455199121 scopus 로고    scopus 로고
    • What do expression dynamics tell us about the mechanism of transcription?
    • D. R. Larson, What do expression dynamics tell us about the mechanism of transcription?, Curr. Opin. Genet. Dev., 21 (2011), pp. 591-599.
    • (2011) Curr. Opin. Genet. Dev. , vol.21 , pp. 591-599
    • Larson, D.R.1
  • 5
    • 33646591544 scopus 로고    scopus 로고
    • Transcriptional Pulsing of a Developmental Gene
    • DOI 10.1016/j.cub.2006.03.092, PII S0960982206014266
    • J. R. Chubb, T. Trcek, S. M. Shenoy, and R. H. Singer, Transcriptional pulsing of a developmental gene, Curr. Biol., 16 (2006), pp. 1018-1025. (Pubitemid 43728209)
    • (2006) Current Biology , vol.16 , Issue.10 , pp. 1018-1025
    • Chubb, J.R.1    Trcek, T.2    Shenoy, S.M.3    Singer, R.H.4
  • 6
    • 38349185928 scopus 로고    scopus 로고
    • Effects of molecular memory and bursting on fluctuations in gene expression
    • J. M. Pedraza and J. Paulsson, Effects of molecular memory and bursting on fluctuations in gene expression, Science, 319 (2008), pp. 339-343.
    • (2008) Science , vol.319 , pp. 339-343
    • Pedraza, J.M.1    Paulsson, J.2
  • 8
    • 79953661480 scopus 로고    scopus 로고
    • Effect of promoter architecture on the cell-to-cell variability in gene expression
    • A. Sanchez, H. G. Garcia, D. Jones, R. Phillips, and J. Kondev, Effect of promoter architecture on the cell-to-cell variability in gene expression, PLoS Comput. Biol., 7 (2011), e1001100.
    • (2011) PLoS Comput. Biol. , vol.7
    • Sanchez, A.1    Garcia, H.G.2    Jones, D.3    Phillips, R.4    Kondev, J.5
  • 11
    • 80052809114 scopus 로고    scopus 로고
    • Varying virulence: Epigenetic control of expression noise and disease processes
    • K. Miller-Jensen, S. S. Dey, D. V. Schaffer, and A. P. Arkin, Varying virulence: Epigenetic control of expression noise and disease processes, Trends Biotechnol., 29 (2011), pp. 517-525.
    • (2011) Trends Biotechnol. , vol.29 , pp. 517-525
    • Miller-Jensen, K.1    Dey, S.S.2    Schaffer, D.V.3    Arkin, A.P.4
  • 12
    • 67749106610 scopus 로고    scopus 로고
    • Synchronous and stochastic patterns of gene activation in the early Drosophila embryo
    • A. N. Boettiger and M. Levine, Synchronous and stochastic patterns of gene activation in the early Drosophila embryo, Science, 325 (2009), pp. 471-473.
    • (2009) Science , vol.325 , pp. 471-473
    • Boettiger, A.N.1    Levine, M.2
  • 13
    • 77249114260 scopus 로고    scopus 로고
    • Variability in gene expression underlies incomplete penetrance
    • A. Raj, S. A. Rifkin, E. Andersen, and A. van Oudenaarden, Variability in gene expression underlies incomplete penetrance, Nature, 463 (2010), pp. 913-918.
    • (2010) Nature , vol.463 , pp. 913-918
    • Raj, A.1    Rifkin, S.A.2    Andersen, E.3    Van Oudenaarden, A.4
  • 14
    • 77956520011 scopus 로고    scopus 로고
    • Functional roles for noise in genetic circuits
    • A. Eldar and M. B. Elowitz, Functional roles for noise in genetic circuits, Nature, 467 (2010), pp. 167-173.
    • (2010) Nature , vol.467 , pp. 167-173
    • Eldar, A.1    Elowitz, M.B.2
  • 15
    • 28944434119 scopus 로고    scopus 로고
    • Real-time kinetics of gene activity in individual bacteria
    • DOI 10.1016/j.cell.2005.09.031, PII S0092867405010378
    • I. Golding, J. Paulsson, S. M. Zawilski, and E. C. Cox, Real-time kinetics of gene activity in individual bacteria, Cell, 123 (2005), pp. 1025-1036. (Pubitemid 41785418)
    • (2005) Cell , vol.123 , Issue.6 , pp. 1025-1036
    • Golding, I.1    Paulsson, J.2    Zawilski, S.M.3    Cox, E.C.4
  • 17
    • 77953383994 scopus 로고    scopus 로고
    • Measurement of single-cell dynamics
    • D. G. Spiller, C. D. Wood, D. A. Rand, and W. R. H. White, Measurement of single-cell dynamics, Nature, 465 (2010), pp. 736-745.
    • (2010) Nature , vol.465 , pp. 736-745
    • Spiller, D.G.1    Wood, C.D.2    Rand, D.A.3    White, W.R.H.4
  • 18
    • 79955381895 scopus 로고    scopus 로고
    • Mammalian genes are transcribed with widely different bursting kinetics
    • D. M. Suter, N. Molina, D. Gatfield, K. Schneider, U. Schibler, and F. Naef, Mammalian genes are transcribed with widely different bursting kinetics, Science, 332 (2011), pp. 472-474.
    • (2011) Science , vol.332 , pp. 472-474
    • Suter, D.M.1    Molina, N.2    Gatfield, D.3    Schneider, K.4    Schibler, U.5    Naef, F.6
  • 20
    • 0017780941 scopus 로고
    • Stochastic model of linear, continuous protein synthesis in bacterial populations
    • D. R. Rigney and W. C. Schieve, Stochastic model of linear, continuous protein synthesis in bacterial populations, J. Theor. Biol., 69 (1977), pp. 761-766.
    • (1977) J. Theor. Biol. , vol.69 , pp. 761-766
    • Rigney, D.R.1    Schieve, W.C.2
  • 21
    • 0026075591 scopus 로고
    • A stochastic model for gene induction
    • M. S. Ko, A stochastic model for gene induction, J. Theor. Biol., 153 (1991), pp. 181-194.
    • (1991) J. Theor. Biol. , vol.153 , pp. 181-194
    • Ko, M.S.1
  • 22
    • 0017833657 scopus 로고
    • A model for the statistical fluctuations of protein numbers in a microbial population
    • DOI 10.1016/0022-5193(78)90326-0
    • O. G. Berg, A model for the statistical fluctuations of protein numbers in a microbial population, J. Theor. Biol., 71 (1978), pp. 587-603. (Pubitemid 8323122)
    • (1978) Journal of Theoretical Biology , vol.71 , Issue.4 , pp. 587-603
    • Berg, O.G.1
  • 23
    • 0000111447 scopus 로고
    • Markovian modelling of gene product synthesis
    • J. Peccoud and B. Ycart, Markovian modelling of gene product synthesis, Theor. Popul. Biol., 48 (1995), pp. 222-234.
    • (1995) Theor. Popul. Biol. , vol.48 , pp. 222-234
    • Peccoud, J.1    Ycart, B.2
  • 24
    • 0034608143 scopus 로고    scopus 로고
    • Random signal fluctuations can reduce random fluctuations in regulated components of chemical regulatory networks
    • J. Paulsson and M. Ehrenberg, Random signal fluctuations can reduce random fluctuations in regulated components of chemical regulatory networks, Phys. Rev. Lett., 84 (2000), pp. 5447-5450.
    • (2000) Phys. Rev. Lett. , vol.84 , pp. 5447-5450
    • Paulsson, J.1    Ehrenberg, M.2
  • 25
    • 19544365454 scopus 로고    scopus 로고
    • Graded and binary responses in stochastic gene expression
    • DOI 10.1088/1478-3967/1/4/001, PII S1478396704828651, 001
    • R. Karmakar and I. Bose, Graded and binary responses in stochastic gene expression, Phys. Biol., 1 (2004), pp. 197-204. (Pubitemid 44362286)
    • (2004) Physical Biology , vol.1 , Issue.4 , pp. 197-204
    • Karmakar, R.1    Bose, I.2
  • 27
    • 33750247101 scopus 로고    scopus 로고
    • Linking stochastic dynamics to population-distribution: An analytical framework of gene expression
    • N. Friedman, L. Cai, and X. S. Xie, Linking stochastic dynamics to population-distribution: An analytical framework of gene expression, Phys. Rev. Lett., 97 (2006), 168302.
    • (2006) Phys. Rev. Lett. , vol.97 , pp. 168302
    • Friedman, N.1    Cai, L.2    Xie, X.S.3
  • 28
    • 56249130793 scopus 로고    scopus 로고
    • Analytical distributions for stochastic gene expression
    • V. Shahrezaei and P. S. Swain, Analytical distributions for stochastic gene expression, Proc. Natl. Acad. Sci. USA., 105 (2008), pp. 17256-17261.
    • (2008) Proc. Natl. Acad. Sci. USA. , vol.105 , pp. 17256-17261
    • Shahrezaei, V.1    Swain, P.S.2
  • 29
    • 65249145254 scopus 로고    scopus 로고
    • Stochasticity of gene products from transcriptional pulsing
    • S. Iyer-Biswas, F. Hayot, and C. Jayaprakash, Stochasticity of gene products from transcriptional pulsing, Phys. Rev. E., 79 (2009), 031911.
    • (2009) Phys. Rev. E. , vol.79 , pp. 031911
    • Iyer-Biswas, S.1    Hayot, F.2    Jayaprakash, C.3
  • 30
    • 79551645801 scopus 로고    scopus 로고
    • Intrinsic noise in stochastic models of gene expression with molecular memory and bursting
    • T. Jia and R. V. Kulkarni, Intrinsic noise in stochastic models of gene expression with molecular memory and bursting, Phys. Rev. Lett., 106 (2011), 058102.
    • (2011) Phys. Rev. Lett. , vol.106 , pp. 058102
    • Jia, T.1    Kulkarni, R.V.2
  • 31
    • 66149144779 scopus 로고    scopus 로고
    • A stochastic spectral analysis of transcriptional regulatory cascades
    • A. M. Walczak, A. Mugler, and C. H. Wiggins, A stochastic spectral analysis of transcriptional regulatory cascades, Proc. Natl. Acad. Sci. USA., 106 (2009), pp. 6529-6534.
    • (2009) Proc. Natl. Acad. Sci. USA. , vol.106 , pp. 6529-6534
    • Walczak, A.M.1    Mugler, A.2    Wiggins, C.H.3
  • 32
    • 70449127534 scopus 로고    scopus 로고
    • Spectral solutions to stochastic models of gene expression with bursts and regulation
    • A. Mugler, A. M. Walczak, and C. H. Wiggins, Spectral solutions to stochastic models of gene expression with bursts and regulation, Phys. Rev. E, 80 (2009), 041921.
    • (2009) Phys. Rev. e , vol.80 , pp. 041921
    • Mugler, A.1    Walczak, A.M.2    Wiggins, C.H.3
  • 33
    • 77954124708 scopus 로고    scopus 로고
    • Post-transcriptional regulation of noise in protein distributions during gene expression
    • T. Jia and R. V. Kulkarni, Post-transcriptional regulation of noise in protein distributions during gene expression, Phys. Rev. Lett., 105 (2010), 018101.
    • (2010) Phys. Rev. Lett. , vol.105 , pp. 018101
    • Jia, T.1    Kulkarni, R.V.2
  • 34
    • 76649120213 scopus 로고    scopus 로고
    • Conversion of graded to binary response in an activator-repressor system
    • R. Karmakar, Conversion of graded to binary response in an activator-repressor system, Phys. Rev. E, 81 (2010), 021905.
    • (2010) Phys. Rev. e , vol.81 , pp. 021905
    • Karmakar, R.1
  • 35
    • 79961052335 scopus 로고    scopus 로고
    • Exact time-dependent solutions for a self-regulating gene
    • A. F. Ramos, G. C. P. Innocentini, and J. E. M. Hornos, Exact time-dependent solutions for a self-regulating gene, Phys. Rev. E, 83 (2011), 062902.
    • (2011) Phys. Rev. e , vol.83 , pp. 062902
    • Ramos, A.F.1    Innocentini, G.C.P.2    Hornos, J.E.M.3
  • 36
    • 79351468987 scopus 로고    scopus 로고
    • Molecular distributions in gene regulatory dynamics
    • M. C. Mackey, M. Tyran-Kamiska, and R. Yvinec, Molecular distributions in gene regulatory dynamics, J. Theor. Biol., 274 (2011), pp. 84-96.
    • (2011) J. Theor. Biol. , vol.274 , pp. 84-96
    • MacKey, M.C.1    Tyran-Kamiska, M.2    Yvinec, R.3
  • 37
    • 79960640740 scopus 로고    scopus 로고
    • Determining the stability of genetic switches: Explicitly accounting for mRNA noise
    • M. Assaf, E. Roberts, and Z. Luthey-Schulten, Determining the stability of genetic switches: Explicitly accounting for mRNA noise, Phys. Rev. Lett., 106 (2011), 248102.
    • (2011) Phys. Rev. Lett. , vol.106 , pp. 248102
    • Assaf, M.1    Roberts, E.2    Luthey-Schulten, Z.3
  • 41
    • 0842285841 scopus 로고    scopus 로고
    • Summing up the noise in gene networks
    • DOI 10.1038/nature02257
    • J. Paulsson, Summing up the noise in gene networks, Nature, 427 (2004), pp. 415-418. (Pubitemid 38168488)
    • (2004) Nature , vol.427 , Issue.6973 , pp. 415-418
    • Paulsson, J.1
  • 42
    • 20344389483 scopus 로고    scopus 로고
    • Models of stochastic gene expression
    • DOI 10.1016/j.plrev.2005.03.003, PII S1571064505000138
    • J. Paulsson, Models of stochastic gene expression, Phys. Life Rev., 2 (2005), pp. 157-175. (Pubitemid 40792434)
    • (2005) Physics of Life Reviews , vol.2 , Issue.2 , pp. 157-175
    • Paulsson, J.1
  • 44
    • 0035193294 scopus 로고    scopus 로고
    • Stochasticity in transcriptional regulation: Origins, consequences, and mathematical representations
    • T. B. Kepler and T. C. Elston, Stochasticity in transcriptional regulation: Origins, consequences, and mathematical representations, Biophys. J., 81 (2001), pp. 3116-3136. (Pubitemid 33111463)
    • (2001) Biophysical Journal , vol.81 , Issue.6 , pp. 3116-3136
    • Kepler, T.B.1    Elston, T.C.2
  • 46
    • 25444468618 scopus 로고    scopus 로고
    • Molecular biology - Noise in gene expression: Origins, consequences, and control
    • DOI 10.1126/science.1105891
    • J. M. Raser and E. K. O'Shea, Noise in gene expression: Origins, consequences, and control, Science, 309 (2005), pp. 2010-2013. (Pubitemid 41362308)
    • (2005) Science , vol.309 , Issue.5743 , pp. 2010-2013
    • Raser, J.M.1    O'Shea, E.K.2
  • 47
    • 33745287724 scopus 로고    scopus 로고
    • Noise in protein expression scales with natural protein abundance
    • DOI 10.1038/ng1807, PII N1807
    • A. Bar-Even, J. Paulsson, N. Maheshri, M. Carmi, E. O'Shea, Y. Pilpel, and N. Barkai, Noise in protein expression scales with natural protein abundance, Nat. Genet., 38 (2006), pp. 636-643. (Pubitemid 43927304)
    • (2006) Nature Genetics , vol.38 , Issue.6 , pp. 636-643
    • Bar-Even, A.1    Paulsson, J.2    Maheshri, N.3    Carmi, M.4    O'Shea, E.5    Pilpel, Y.6    Barkai, N.7
  • 48
    • 79957608918 scopus 로고    scopus 로고
    • General properties of transcriptional time series in Escherichia coli
    • L. H. So, A. Ghosh, C. Zong, L. A. Seplveda, R. Segev, and I. Golding, General properties of transcriptional time series in Escherichia coli, Nat. Genet., 43 (2011), pp. 554-560.
    • (2011) Nat. Genet. , vol.43 , pp. 554-560
    • So, L.H.1    Ghosh, A.2    Zong, C.3    Seplveda, L.A.4    Segev, R.5    Golding, I.6
  • 49
    • 48249138167 scopus 로고    scopus 로고
    • The generation of promotermediated transcriptional noise in bacteria
    • N. Mitarai, I. B. Dodd, M. T. Crooks, and K. Sneppen, The generation of promotermediated transcriptional noise in bacteria, PLoS Comput. Biol., 4 (2008), e1000109.
    • (2008) PLoS Comput. Biol. , vol.4
    • Mitarai, N.1    Dodd, I.B.2    Crooks, M.T.3    Sneppen, K.4
  • 50
    • 55449126379 scopus 로고    scopus 로고
    • Nonidentifiability of the source of intrinsic noise in gene expression from single-burst data
    • P. J. Ingram, M. P. Stumpf, and J. Stark, Nonidentifiability of the source of intrinsic noise in gene expression from single-burst data, PLoS Comput. Biol., 4 (2008), e1000192.
    • (2008) PLoS Comput. Biol. , vol.4
    • Ingram, P.J.1    Stumpf, M.P.2    Stark, J.3
  • 51
    • 33845442827 scopus 로고    scopus 로고
    • Diffusion of transcription factors can drastically enhance the noise in gene expression
    • J. S. van Zon, M. J. Morelli, S. Tnase-Nicola, and P. R. ten Wolde, Diffusion of transcription factors can drastically enhance the noise in gene expression, Biophys. J., 91 (2008), pp. 4350-4367.
    • (2008) Biophys. J. , vol.91 , pp. 4350-4367
    • Van Zon, J.S.1    Morelli, M.J.2    Tnase-Nicola, S.3    Ten Wolde, P.R.4
  • 52
    • 62449302589 scopus 로고    scopus 로고
    • Elongation dynamics shape bursty transcription and translation
    • M. Dobrzynski and F. J. Bruggeman, Elongation dynamics shape bursty transcription and translation, Proc. Natl. Acad. Sci. USA., 106 (2009), pp. 2583-2588.
    • (2009) Proc. Natl. Acad. Sci. USA. , vol.106 , pp. 2583-2588
    • Dobrzynski, M.1    Bruggeman, F.J.2
  • 53
    • 77955568538 scopus 로고    scopus 로고
    • Applications of Little's law to stochastic models of gene expression
    • V. Elgart, T. Jia, and R. V. Kulkarni, Applications of Little's law to stochastic models of gene expression, Phys. Rev. E, 82 (2010), 021901.
    • (2010) Phys. Rev. e , vol.82 , pp. 021901
    • Elgart, V.1    Jia, T.2    Kulkarni, R.V.3
  • 54
    • 79955006805 scopus 로고    scopus 로고
    • Exploring transcription regulation through cellto- cell variability
    • R. Rinott, A. Jaimovich, and N. Friedman, Exploring transcription regulation through cellto- cell variability, Proc. Natl. Acad. Sci. USA., 108 (2011), pp. 6329-6334.
    • (2011) Proc. Natl. Acad. Sci. USA. , vol.108 , pp. 6329-6334
    • Rinott, R.1    Jaimovich, A.2    Friedman, N.3
  • 55
    • 79251603722 scopus 로고    scopus 로고
    • Non-genetic heterogeneity from stochastic partitioning at cell division
    • D. Huh and J. Paulsson, Non-genetic heterogeneity from stochastic partitioning at cell division, Nat. Genet., 43 (2011), pp. 95-100.
    • (2011) Nat. Genet. , vol.43 , pp. 95-100
    • Huh, D.1    Paulsson, J.2
  • 56
    • 33645033645 scopus 로고    scopus 로고
    • Probing gene expression in live cells, one protein molecule at a time
    • J. Yu, J. Xiao, X. Ren, K. Lao, and X. S. Xie, Probing gene expression in live cells, one protein molecule at a time, Science, 311 (2006), pp. 1600-1603.
    • (2006) Science , vol.311 , pp. 1600-1603
    • Yu, J.1    Xiao, J.2    Ren, X.3    Lao, K.4    Xie, X.S.5
  • 57
    • 33645027986 scopus 로고    scopus 로고
    • Stochastic protein expression in individual cells at the single molecule level
    • L. Cai, N. Friedman, and X. S. Xie, Stochastic protein expression in individual cells at the single molecule level, Nature, 440 (2006), pp. 358-362.
    • (2006) Nature , vol.440 , pp. 358-362
    • Cai, L.1    Friedman, N.2    Xie, X.S.3
  • 58
    • 18944401160 scopus 로고    scopus 로고
    • Eukaryotic transcription activation: Right on target
    • DOI 10.1016/j.molcel.2005.04.017, PII S1097276505012803
    • M. R. Green, Eukaryotic transcription activation: Right on target, Mol. Cell, 18 (2005), pp. 399-402. (Pubitemid 40704754)
    • (2005) Molecular Cell , vol.18 , Issue.4 , pp. 399-402
    • Green, M.R.1
  • 62
    • 33645820442 scopus 로고    scopus 로고
    • Transcription in four dimensions: Nuclear receptordirected initiation of gene expression
    • R. Metivier, G. Reid, and F. Gannon, Transcription in four dimensions: Nuclear receptordirected initiation of gene expression, EMBO Rep., 7 (2006), pp. 161-167.
    • (2006) EMBO Rep. , vol.7 , pp. 161-167
    • Metivier, R.1    Reid, G.2    Gannon, F.3
  • 66
    • 33645429016 scopus 로고
    • Exact stochastic simulation of coupled chemical reactions
    • D. Gillespie, Exact stochastic simulation of coupled chemical reactions, J. Phys. Chem., 81 (1977), pp. 2340-2361.
    • (1977) J. Phys. Chem. , vol.81 , pp. 2340-2361
    • Gillespie, D.1
  • 67
    • 56249126960 scopus 로고
    • A note on the relationship between the geometric and exponential distributions
    • B. J. Prochaska, A note on the relationship between the geometric and exponential distributions, Amer. Statist., 27 (1973), p. 27.
    • (1973) Amer. Statist. , vol.27 , pp. 27
    • Prochaska, B.J.1
  • 69
    • 48349117552 scopus 로고    scopus 로고
    • A review of results on sums of random variables
    • S. Nadarajah, A review of results on sums of random variables, Acta. Appl. Math., 103 (2008), pp. 131-140.
    • (2008) Acta. Appl. Math. , vol.103 , pp. 131-140
    • Nadarajah, S.1
  • 70
    • 77955102352 scopus 로고    scopus 로고
    • Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells
    • Y. Taniguchi, P. J. Choi, G. W. Li, H. Chen, M. Babu, J. Hearn, A. Emili, and X. S. Xie, Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells, Science, 329 (2010), pp. 533-538.
    • (2010) Science , vol.329 , pp. 533-538
    • Taniguchi, Y.1    Choi, P.J.2    Li, G.W.3    Chen, H.4    Babu, M.5    Hearn, J.6    Emili, A.7    Xie, X.S.8
  • 71
    • 38549126635 scopus 로고    scopus 로고
    • Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter
    • DOI 10.1126/science.1150559
    • S. Karpova, M. J. Kim, C. Spriet, K. Nalley, T. J. Stasevich, Z. Kherrouche, L. Heliot, and J. G. McNally, Concurrent fast and slow cycling of a transcriptional activator at an endogenous promoter, Science, 319 (2008), pp. 466-469. (Pubitemid 351160580)
    • (2008) Science , vol.319 , Issue.5862 , pp. 466-469
    • Karpova, T.S.1    Kim, M.J.2    Spriet, C.3    Nalley, K.4    Stasevich, T.J.5    Kherrouche, Z.6    Heliot, L.7    McNally, J.G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.