Induction of apoptosis and inhibition of cell proliferation by the cyclooxgenase enzyme blocker nimesulide in the Ishikawa endometrial cancer cell line

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 164, Issue 1, 2012, Pages 79-84

  Özalp, S Sinan ^a   Eren, Ceren Yildiz ^a   Bostancioglu, Rakibe Beklem ^b   Koparal, Ayşe Tansu ^b  

^a ESKISEHIR OSMANGAZI UNIVERSITY   (Turkey)

^b ANADOLU UNIVERSITY   (Turkey)

Author keywords

Apoptosis; COX 2; Cytotoxicity; Endometrial cancer; Nimesulide

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4',6 DIAMIDINO 2 PHENYLINDOLE; CASPASE 3; CISPLATIN; NIMESULIDE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; COLORIMETRY; CONTROLLED STUDY; CYTOTOXICITY; ENDOMETRIUM CANCER; ENZYME ACTIVATION; ENZYME ASSAY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL;

EID: 84865685764     PISSN: 03012115     EISSN: 18727654     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2012.05.018     Document Type: Article

References (39)

1. H. Li, N. Takai, and A. Yuge Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells Cancer Letters 297 2010 198 206
2. J.I. Sorosky Endometrial cancer Obstetrics and Gynecology 111 2008 436 447
3. D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70
4. D.L. Vaux, and S.J. Korsmeyer Cell death in development Cell 96 1999 245 254
5. S.Y. Sun, J.R.N. Hail, and R. Lotan Apoptosis as a novel target for cancer chemoprevention Journal of the National Cancer Institute 96 2004 662 672
6. B.G. Köseoglu, Ş. Öztürk, and H. Koçak The effects of etodolac, nimesulide and naproxen sodium on the frequency of sister chromatid exchange after enclused third molars surgery Yonsei Medical Journal 49 5 2008 742 747
7. R.N. Beata, F. Wojciech, and S. Stanisław The influence of anti-inflammatory drugs on the proliferation of fibroblast derived from nasal polyps Auris, Nasus, Larynx 32 2005 225 229
8. R.E. Harris, R.T. Chlebowski, and R.D. Jackson Breast cancer and nonsteroidal anti-inflammatory drugs: prospective results from the Women's Health Initiative Cancer Research 63 2003 6096 6101
9. B.M. Deasy, O'Sullivan-Coyne, and T.R. O'Donovan Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E2-independent mechanisms Cancer Letters 256 2007 246 258
10. A.J. Dannenberg, N.K. Altorki, and J.O. Boyle Cyclo-oxygenase 2: a pharmacological target fort he prevention of cancer Lancet Oncology 2 2001 544 551
11. G. Gasparini, R. Longo, and R. Sarmiento Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents? Lancet Oncology 4 2003 605 615
12. G. Ferrandina, F. Legge, and R.O. Ranelletti Cyclooxygenase-2 expression in endometrial carcinoma: correlation with clinicopathological parameters and clinical outcome Cancer 95 2002 801 807
13. G. Kilic, B. Gurates, and J. Garon Expression of cyclooxygenase-2 in endometrial adenocarcinoma European Journal of Gynaecological Oncology 26 2005 271 274
14. M.E. St-Germain, V. Gagnon, and I. Mathieu Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells International Journal of Oncology 24 2004 1311 1324
15. J.L. Masferrer, K.M. Leahy, and A.T. Koki Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors Cancer Research 60 2000 1306 1311
16. A.C. Abrahao, R.M. Castilho, and C.H. Squarize A role for COX2-derived PGE2 and PGE2-receptor subtypes in head and neck squamous carcinoma cell proliferation Oral Oncology 46 2010 880 887
17. S. Hazra, and S. Dubinett Ciglitazone mediates COX-2 dependent suppression of PGE2 in human non-small cell lung cancer cells Prostaglandins Leukotrines and Fatty Acids 77 2007 51 58
18. S. Genç, E. Attar, and F. Gürdöl The effect of COX-2 inhibitor, nimesulide, on angiogenic factors in primary endometrial carcinoma cell culture Clinical and Experimental Medicine 1 2007 6 10
19. K. Hasegawa, Y. Ohashi, and K. Ishikawa Expression of cyclooxygenase-2 in uterine endometrial cancer and anti-tumor effects of a selective COX-2 inhibitor International Journal of Oncology 26 2005 1419 1428
20. L. Yu, M. Chen, and Z. Li Celecoxib antagonizes the cytotoxicity of cisplatin in human esophageal squamous cell carcinoma cells by reducing intracellular cisplatin accumulation Molecular Pharmacology 79 2011 608 617
21. O. Dormond, A. Foletti, C. Paroz, and C. Guegg NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis Nature Medicine 7 2001 1041 1047
22. P. Ben-Av, L.J. Crofford, L. Wilder, and T. Hla Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E interleukin-1: a potential mechanism for inflammatory angiogenesis FEBS Letters 72 1995 83 87
23. B. Chen, B. Su, and S. Chen A COX-2 inhibitor nimesulide analog selectively induces apoptosis in Her2 overexpressing breast cancer cells via cytochrome c dependent mechanisms Biochemical Pharmacology 77 2009 1787 1794
24. T. Thigpen, J. Blessing, H. Homesley, W.T. Creasman, and G. Sutton Phase II trial of cisplatin as first-line chemotherapy in patients with advanced or recurrent endometrial carcinoma: a Gynecologic Oncology Group study Cancer Treatment Reports 33 1989 68 70
25. J.P. Delord, C. Puozzo, F. Lefresne, and R. Bugat Combination chemotherapy of vinorelbine and cisplatin: a phase I pharmacokinetic study in patients with metastatic solid tumors Anticancer Research 29 2009 553 560
26. A.T. Koparal, G. Ulus, M. Zeytinoglu, T. Tay, and A.O. Türk Angiogenesis inhibition by a lichen compound olivetoric acid Phytotherapy Research 24 2010 754 758
27. R.B. Bostancioglu, K. Işik, H. Genc, K. Benkli, and A.T. Koparal Studies on the cytotoxic, apoptotic and antitumoral effects of Au(III), Pt(II) complexes of 1,10-phenanthroline on V79 379A and A549 cell lines Journal of Enzyme Inhibition and Medicinal Chemistry 27 3 2012 458 466 10.3109/14756366. 2011.596835
28. M. Castedo, K. Feri, T. Roumier, D. Metivier, N. Zamzami, and G. Kroemer Quantitation of mitochondrial alterations associated with apoptosis Journal of Immunological Methods 265 2002 39 47
29. A. Sebastian, E. Allan, and D. Allan Addition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy Journal of Dermatological Science 64 3 2011 174 184
30. R.P. Pang, J.G. Zhou, and Z.R.ET-AL> Zeng Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3B/NAG-1 pathway Cancer Letters 251 2007 268 277
31. J.W. Tiju, Y.H. Liao, and S.J.ET-AL> Lin Cyclooxugenase-2 overexpression in human basal cell carcinoma cell line increases antiapoptosis, angiogenesis, and tumorigenesis Journal of Investigative Dermatology 126 2006 1143 1151
32. K. Kashfi, and B. Rigas Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention Biochemical Pharmacology 70 2005 969 986
33. A.J. Dannenberg, and K. Subbaramaiah Targeting cyclooxygenase-2 in human neoplasia: rationale and promise Cancer Cell 4 2003 431 436
34. B. Su, M.V. Darby, and R.W. Brueggemeier Synthesis and biological evaluation of novel sulfonanilide compounds as antiproliferative agents for breast cancer Journal of Combinatorial Chemistry 10 2008 475 483
35. D. Wang, J.N.T. Fung, Y. Tuo, L. Hu, and C. Chen TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway Cancer Letters 294 2010 91 100
36. K. Kuribayashi, P.A. Mayes, and W.S. El-Deiry What are caspases 3 and 7 doing upstream of the mitochondria? Cancer Biology and Therapy 5 2006 763 765
37. L. Wang, T. Chen, J. Qu, and X. Wei Quantitative analysis of caspase-3 activation by fitting fluorescence emission spectra in living cells Micron 40 2009 811 820
38. B.K. Singh, M. Tripathi, P.K. Pandey, and P. Kakar Nimesulide aggravates redox imbalance and calcium dependent mitochondrial permeability transition leading to dysfunction in vitro Toxicology 275 2010 1 9
39. X. Ma, N. Kundu, and S. Rifat Prostaglandin E receptor EP4 antagonism inhibits breast cancer metastasis Cancer Research 66 2006 2923 2927