Studies on the cytotoxic, apoptotic and antitumoral effects of Au(III) and Pt(II) complexes of 1, 10-phenanthroline on V79 379A and A549 cell lines

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 27, Issue 3, 2012, Pages 458-466

  Bostancoǧlu, R Beklem ^a   Işik, Kenan ^a   Genç, Hatice ^a   Benkli, Kadriye ^a   Koparal, Ayşe Tansu ^a  

^a ANADOLU UNIVERSITY   (Turkey)

Author keywords

active caspase 3; apoptosis; Au(III); colony forming ability assay (CFA); cytotoxicity; DAPI staining; DNA fragmentation; MTT assay; Pt(II)

Indexed keywords

1,10 PHENANTHROLINE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4',6 DIAMIDINO 2 PHENYLINDOLE; ANTINEOPLASTIC AGENT; CASPASE 3; CYTOTOXIC AGENT; GOLD; PLATINUM;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; COLONY FORMING CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE; CELL PROLIFERATION; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; HUMANS; ORGANOGOLD COMPOUNDS; ORGANOPLATINUM COMPOUNDS; PHENANTHROLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

CRICETULUS GRISEUS;

EID: 84860384775     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2011.596835     Document Type: Article

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