Sp1 expression regulates lung tumor progression

Oncogene

Volumn 31, Issue 35, 2012, Pages 3973-3988

  Hsu, T I ^a,b   Wang, M C ^a   Chen, S Y ^b   Yeh, Y M ^a   Su, W C ^a   Chang, W C ^a,b,c   Hung, J J ^a,b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

E cadherin; metastasis; Sp1

Indexed keywords

BETA CATENIN; COMPLEMENTARY DNA; DOXYCYCLINE; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; MITHRAMYCIN; MITHRAMYCIN A; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

ADENOVIRUS; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER INVASION; CANCER STAGING; CANCER SURVIVAL; CELL MIGRATION; CELL PROLIFERATION; FEMALE; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; LUNG TUMOR; MAJOR CLINICAL STUDY; MALE; METASTASIS; MOUSE; NONHUMAN; ONCOGENE K RAS; PRIORITY JOURNAL; PROGNOSIS; TRANSGENIC MOUSE; TUMOR GROWTH; WOUND HEALING;

ADENOCARCINOMA; ANIMALS; BETA CATENIN; CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MICE; MICE, TRANSGENIC; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; SP1 TRANSCRIPTION FACTOR;

MUS MUSCULUS;

EID: 84865652666     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.568     Document Type: Article

References (44)

1. Black AR, Black JD, Azizkhan-Clifford J. (2001). Sp1 and kruppel-like factor family of transcription factors in cell growth regulation and cancer. J Cell Physiol 188: 143-160.
2. Bremnes RM, Veve R, Hirsch FR, Franklin WA. (2002). The E-cadherin cell-cell adhesion complex and lung cancer invasion, metastasis, and prognosis. Lung Cancer 36: 115-124.
3. Bu Y, Gao L, Gelman IH. (2010). Role for transcription factor TFII-I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src. Int J Cancer 128: 1836-42.
4. Chang HC, Liu LT, Hung WC. (2004). Involvement of histone deacetylation in ras-induced down-regulation of the metastasis suppressor RECK. Cell Signal 16: 675-679.
5. Chao YC, Pan SH, Yang SC, Yu SL, Che TF, Lin CW et al. (2009). Claudin-1 is a metastasis suppressor and correlates with clinical outcome in lung adenocarcinoma. Am J Respir Crit Care Med 179: 123-133.
6. Chen J, Ye L, Xie F, Yang Y, Zhang L, Jiang WG. (2010). Expression of bone morphogenetic protein 7 in lung cancer and its biological impact on lung cancer cells. Anticancer Res 30: 1113-1120.
7. Chu YW, Yang PC, Yang SC, Shyu YC, Hendrix MJ, Wu R et al. (1997). Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line. Am J Respir Cell Mol Biol 17: 353-360.
8. Chuang JY, Wang YT, Yeh SH, Liu YW, Chang WC, Hung JJ. (2008). Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis. Mol Biol Cell 19: 1139-1151.
9. Chuang JY, Wu CH, Lai MD, Chang WC, Hung JJ. (2009). Overexpression of Sp1 leads to p53-dependent apoptosis in cancer cells. Int J Cancer 125: 2066-2076.
10. DeFino MC, Wacker JL, Lyssand JS, Wang EH, Hague C. (2010). Differential regulation of GPR54 transcription by specificity protein-1 and partial estrogen response element in mouse pituitary cells. Biochem Biophys Res Commun 393: 603-608.
11. Denlinger CE, Ikonomidis JS, Reed CE, Spinale FG. (2010). Epithelial to mesenchymal transition: the doorway to metastasis in human lung cancers. J Thorac Cardiovasc Surg 140: 505-513.
12. Duverger V, Murphy AM, Sheehan D, England K, Cotter TG, Hayes I et al. (2004). The anticancer drug mithramycin A sensitises tumour cells to apoptosis induced by tumour necrosis factor (TNF). Br J Cancer 90: 2025-2031.
13. Esteve PO, Chin HG, Pradhan S. (2007). Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells. J Biol Chem 282: 2615-2625.
14. Fisher GH, Wellen SL, Klimstra D, Lenczowski JM, Tichelaar JW, Lizak MJ et al. (2001). Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. Genes Dev 15: 3249-3262.
15. Frixen UH, Behrens J, Sachs M, Eberle G, Voss B, Warda A et al. (1991). E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 113: 173-185.
16. Hommura F, Furuuchi K, Yamazaki K, Ogura S, Kinoshita I, Shimizu M et al. (2002). Increased expression of beta-catenin predicts better prognosis in nonsmall cell lung carcinomas. Cancer 94: 752-758.
17. Hung TL, Chen FF, Liu JM, Lai WW, Hsiao AL, Huang WT et al. (2003). Clinical evaluation of HER-2/neu protein in malignant pleural effusion-associated lung adenocarcinoma and as a tumor marker in pleural effusion diagnosis. Clin Cancer Res 9: 2605-2612.
18. Innocente SA, Lee JM. (2005). p53 is a NF-Y-and p21-independent, Sp1-dependent repressor of cyclin B1 transcription. FEBS Lett 579: 1001-1007.
19. Jemal A, Siegel R, Xu J, Ward E. (2010). Cancer statistics, 2010. CA Cancer J Clin 60: 277-300.
20. Jiang Y, Wang L, Gong W, Wei D, Le X, Yao J et al. (2004). A high expression level of insulin-like growth factor I receptor is associated with increased expression of transcription factor Sp1 and regional lymph node metastasis of human gastric cancer. Clin Exp Metastasis 21: 755-764.
21. Kumar AP, Butler AP. (1999). Enhanced Sp1 DNA-binding activity in murine keratinocyte cell lines and epidermal tumors. Cancer Lett 137: 159-165.
22. Kwak HJ, Park MJ, Cho H, Park CM, Moon SI, Lee HC et al. (2006). Transforming growth factor-beta1 induces tissue inhibitor of metalloproteinase-1 expression via activation of extracellular signal-regulated kinase and Sp1 in human fibrosarcoma cells. Mol Cancer Res 4: 209-220.
23. Lee YC, Oslund KL, Thai P, Velichko S, Fujisawa T, Duong T et al. (2011). 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent/EGFR/ERK/p38-dependent SP1-based transcription. Am J Respir Cell Mol Biol 45: 270-276.
24. Leroy I, Laurent G, Quillet-Mary A. (2006). Mithramycin A activates Fas death pathway in leukemic cell lines. Apoptosis 11: 113-119.
25. Lin RK, Hsu CH, Wang YC. (2007). Mithramycin A inhibits DNA methyltransferase and metastasis potential of lung cancer cells. Anticancer Drugs 18: 1157-1164.
26. Liu YN, Lee WW, Wang CY, Chao TH, Chen Y, Chen JH. (2005). Regulatory mechanisms controlling human E-cadherin gene expression. Oncogene 24: 8277-8290.
27. Lou Z, O'Reilly S, Liang H, Maher VM, Sleight SD, McCormick JJ. (2005). Down-regulation of overexpressed sp1 protein in human fibrosarcoma cell lines inhibits tumor formation. Cancer Res 65: 1007-1017.
28. Maor S, Mayer D, Yarden RI, Lee AV, Sarfstein R, Werner H et al. (2006). Estrogen receptor regulates insulin-like growth factor-I receptor gene expression in breast tumor cells: involvement of transcription factor Sp1. J Endocrinol 191: 605-612.
29. McCarty Jr KS, Miller LS, Cox EB, Konrath J, McCarty Sr KS. (1985). Estrogen receptor analyses. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies. Arch Pathol Lab Med 109: 716-721.
30. Mitchell DC, Stafford LJ, Li D, Bar-Eli M, Liu M. (2007). Transcriptional regulation of KiSS-1 gene expression in metastatic melanoma by specificity protein-1 and its coactivator DRIP-130. Oncogene 26: 1739-1747.
31. Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B et al. (1997). Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 275: 1787-1790.
32. Nicolas M, Noe V, Jensen KB, Ciudad CJ. (2001). Cloning and characterization of the 5-flanking region of the human transcription factor Sp1 gene. J Biol Chem 276: 22126-22132.
33. Remsing LL, Bahadori HR, Carbone GM, McGuffie EM, Catapano CV, Rohr J. (2003). Inhibition of c-src transcription by mithramycin: structure-activity relationships of biosynthetically produced mithramycin analogues using the c-src promoter as target. Biochemistry 42: 8313-8324.
34. Rivard N. (2009). Phosphatidylinositol 3-kinase: a key regulator in adherens junction formation and function. Front Biosci 14: 510-522.
35. Roose J, Huls G, van Beest M, Moerer P, van der Horn K, Goldschmeding R et al. (1999). Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1. Science 285: 1923-1926.
36. Schmalhofer O, Brabletz S, Brabletz T. (2009). E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer. Cancer Metastasis Rev 28: 151-166.
37. St Clair S, Manfredi JJ. (2006). The dual specificity phosphatase Cdc25C is a direct target for transcriptional repression by the tumor suppressor p53. Cell Cycle 5: 709-713.
38. Su K, Roos MD, Yang X, Han I, Paterson AJ, Kudlow JE. (1999). An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro. J Biol Chem 274: 15194-15202.
39. Sun X, Ritzenthaler JD, Zhong X, Zheng Y, Roman J, Han S. (2009). Nicotine stimulates PPARbeta/delta expression in human lung carcinoma cells through activation of PI3K/mTOR and suppression of AP-2alpha. Cancer Res 69: 6445-6453.
40. Tsai MF, Wang CC, Chang GC, Chen CY, Chen HY, Cheng CL et al. (2006). A new tumor suppressor DnaJ-like heat shock protein, HLJ1, and survival of patients with non-small-cell lung carcinoma. J Natl Cancer Inst 98: 825-838.
41. Wang YT, Chuang JY, Shen MR, Yang WB, Chang WC, Hung JJ. (2008). Sumoylation of specificity protein 1 augments its degradation by changing the localization and increasing the specificity protein 1 proteolytic process. J Mol Biol 380: 869-885.
42. Wierstra I. (2008). Sp1: emerging roles-beyond constitutive activation of TATA-less housekeeping genes. Biochem Biophys Res Commun 372: 1-13.
43. Yi T, Tan K, Cho SG, Wang Y, Luo J, Zhang W et al. (2010). Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2-and Sp1-mediated Bmp7 expression. J Biol Chem 285: 17811-17820.
44. Zheng Y, Ritzenthaler JD, Sun X, Roman J, Han S. (2009). Prostaglandin E2 stimulates human lung carcinoma cell growth through induction of integrin-linked kinase: the involvement of EP4 and Sp1. Cancer Res 69: 896-904.