Enhanced Sp1 DNA-binding activity in murine keratinocyte cell lines and epidermal tumors

Cancer Letters

Volumn 137, Issue 2, 1999, Pages 159-165

  Kumar, Addanki P ^a   Butler, Andrew P ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Ornithine decarboxylase; Sp1 DNA binding; Sp1 expression

Indexed keywords

ORNITHINE DECARBOXYLASE; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BINDING SITE; CARCINOGENESIS; CONTROLLED STUDY; DNA BINDING; KERATINOCYTE; MOUSE; NEWBORN; NONHUMAN; POLYAMINE SYNTHESIS; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH;

ANIMALS; ANIMALS, NEWBORN; BINDING, COMPETITIVE; CARCINOMA, SQUAMOUS CELL; CELL LINE; CELL LINE, TRANSFORMED; CELL NUCLEUS; DNA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KERATINOCYTES; MICE; MICE, INBRED SENCAR; OLIGONUCLEOTIDES; PAPILLOMA; RNA, MESSENGER; SKIN NEOPLASMS; SP1 TRANSCRIPTION FACTOR;

EID: 0032925475     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00351-6     Document Type: Article

References (33)

1. Pegg A., Shantz L., Coleman C. Ornithine decarboxylase as a target for chemoprevention. J. Cell Biochem. 22:1995;132-138.
2. Heby O., Persson L. Molecular genetics of polyamine synthesis in eukaryotic cells. Trends Biochem. Sci. 15:1990;153-158.
3. Moshier J.A., Dosescu J., Skunca M., Luk G.D. Transformation of NIH/3T3 cells by ornithine decarboxylase overexpression. Cancer Res. 53:1993;2618-2622.
4. Auvinen M., Paasinen A., Anderson L.C., Holtta E. Ornithine decarboxylase activity is critical for cell transformation. Nature. 360:1992;355-358.
5. Clifford A., Morgan D., Yuspa S.H., Soler A.P., Gilmour S.K. Role of ornithine decarboxylase in epidermal tumorigenesis. Cancer Res. 55:1995;1680-1686.
6. Gilmour S.K., Verma A.K., Madara T., O'Brien T.G. Regulation of ornithine decarboxylase gene expression in mouse epidermis epidermal tumors during two-stage tumorigenesis. Cancer Res. 47:1987;1221-1225.
7. Koza R.A., Meghosh L.C., Palmieri M., O'Brien T. Constitutively elevated levels of ornithine and polyamines in mouse epidermal papillomas. Carcinogenesis. 12:1991;1619-1625.
8. Megosh L., Gilmour S.K., Rosson D., Soler A.P., Blessing M., Sawicki J.A., O'Brien T.G. Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase. Cancer Res. 55:1995;4205-4209.
9. Kumar A.P., Mar P.K., Zhao B., Montgomery R.L., Kang D.-C., Butler A.P. Regulation of rat ornithine decarboxylase promoter activity by binding of transcription factor Sp1. J. Biol. Chem. 270:1995;4341-4348.
10. Kumar A.P., Butler A.P. Transcription factor Sp3 antagonizes activation of the ornithine decarboxylase promoter by Sp1. Nucleic Acids Res. 25:1997;2012-2019.
11. Lee W.Y., Butler A.P., Locniskar M.F., Fischer S.M. Signal transduction pathway(s) involved in phorbol ester and autocrine induction of interleukin-1α mRNA in murine keratinocytes. J. Biol. Chem. 269:1994;17971-17980.
12. Conti C.J., Fries K.W., Vijae A., Miller D.R., Slaga T.J. In vivo behaviour of murine epidermal cell lines derived from initiated and noninitiated skin. Cancer Res. 48:1988;435-439.
13. Dignam J.D., Lebovity R.M., Roeder R.G. Accurate transcription initiated by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1983;1475-1488.
14. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
15. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: A Laboratory Manual. 2nd :1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
16. Kennard M.D., Kang D.-C., Montgomery R.L., Butler A.P. Expression of epidermal ornithine decarboxylase and nuclear proto-oncogenes in phorbol ester tumor promotion-sensitive and resistant mice. Mol. Carcinogenesis. 11:1994;14-22.
17. Hagen G., Mueller S., Beato M., Suske G. Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J. 13:1994;3843-3851.
18. Rafty L.A., Khachigian L.M. Zinc finger transcription factors mediate high constitutive platelet-derived growth factor-B expression in smooth muscle cells derived from aortae of newborn rats. J. Biol. Chem. 273:1998;5758-5764.
19. Borellini F., He Y.F., Aquino A., Yu G., Josephs S.F., Glazer R.I. Increased DNA binding and transcriptional activity associated with transcription factor Sp1 in K562 cells transfected with the myeloid-specific c-fes tyrosine kinase gene. J. Biol. Chem. 266:1991;15850-15854.
20. Yurochko A.D., Mayo M.W., Poma E.E., Baldwin A.S. Jr., Huang E.-S. Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates up regulation of the p65 and p105/p50 NF-κB promoters. J. Virol. 71:1997;4638-4648.
21. Noe V., Chen C., Alemany C., Nicolas M., Caragol I., Chasin L.A., Ciudad C.J. Cell-growth regulation of the hamster dihydrofolate reductase gene promoter by transcription factor Sp. Eur. J. Biochem. 249:1997;13-20.
22. A.P. Kumar, Butler, A.P., [1998] Serum-responsive gene expression mediated by Sp1, Submitted.
23. Dharmavaram R.M., Liu G., Moweres S.D., Jimenez S.A. Detection and characterization of Sp1 binding activity in human chondrocytes and its alterations during chondrocyte dedifferentiation. J. Biol. Chem. 272:1997;26918-26925.
24. Armstrong S.A., Barry D.A., Leggett R.W., Mueller C.R. Casein kinase CKII-mediated phosphorylation of the C-terminus of Sp1 decreases its DNA binding activity. J. Biol. Chem. 272:1997;13489-13495.
25. Vinals F., Fandos C., Santalucia T., Ferre J., Testar X., Palacin M., Zorzano A. Myogenesis and MyoD down-regulate Sp1. J. Biol. Chem. 272:1997;12913-12921.
26. Kitadai Y., Yasui W., Yokozaki H., Kuniyasu H., Haruma K., Kajiyama G., Tahara E. The level of a transcription factor Sp1 is correlated with the expression of EGF receptor in human gastric carcinomas. Biochem. Biophys. Res. Commun. 189:1992;1342-1348.
27. Butler A.P., Johnson D.G., Kumar A.P., Narayan S., Wilson S.H., MacLeod M.C. Disruption of transcription in vitro and gene expression in vivo by DNA adducts derived from a benzo[a]pyrene diol epoxide located in heterologous sequences. Carcinogenesis. 18:1997;239-244.
28. Gunther M., Frebourg T., Laithier M., Fossar N., Bouziane-Ouartini M., Lavialle C., Brison O. An Sp1 binding site and the minimal promoter contribute to overexpression of the cytokeratin 18 gene in tumorigenic clones relative to that in nontumorigenic clones of a human carcinoma cell line. Mol. Cell. Biol. 15:1995;2490-2499.
29. Saffer J.D., Jackson S.P., Annarella M.B. Developmental expression of Sp1 in the mouse. Mol. Cell. Biol. 11:1991;2189-2199.
30. Sakai T., Ohtani N., McGee T.L., Robbins P.D., Dryja T.P. Oncogenic germ-line mutations in Sp1 and ATF sites in the human retinoblastoma gene. Nature. 353:1991;83-86.
31. Kovisto U.-M., Palvimo J.J., Janne O.A., Kontula K. A single-base substitution in the proximal Sp1 site of the human low density lipoprotein receptor promoter as a cause of heterozygous familial hypercholesterolemia. Proc. Natl. Acad. Sci. USA. 91:1994;10526-10530.
32. Bello-Fernandez C., Packham G., Cleveland J.L. The ornithine decarboxylase gene is a transcriptional target of c-Myc. Proc. Natl. Acad. Sci. USA. 90:1993;7804-7808.
33. Wrighton W., Busslinger M. Direct transcriptional stimulation of the ornithine decarboxylase gene by Fos in PC12 cells but not in fibroblasts. Mol. Cell. Biol. 13:1993;4657-4669.