Heterodivalent linked macrocyclic β-sheets with enhanced activity against aβ aggregation: Two sites are better than one

Journal of the American Chemical Society

Volumn 134, Issue 34, 2012, Pages 14179-14184

  Cheng, Pin Nan ^a   Spencer, Ryan ^a   Woods, R Jeremy ^a   Glabe, Charles G ^a   Nowick, James S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOIDOGENIC PEPTIDES; C-TERMINAL REGIONS; EQUIMOLAR CONCENTRATIONS; FLUORESCENCE ASSAY; MACROCYCLICS; MOLECULAR TEMPLATE; MULTIPLE REGIONS; PENTAPEPTIDES; SHEET COMPONENTS; SHEET STRUCTURE; THIOFLAVIN T;

PROTEINS;

OLIGOMERS;

AMYLOID BETA PROTEIN; MACROCYCLIC COMPOUND; OLIGOMER; THIOFLAVINE;

ARTICLE; BETA SHEET; FLUORESCENCE ANALYSIS;

AMYLOID BETA-PEPTIDES; HUMANS; MODELS, MOLECULAR; PEPTIDES, CYCLIC; PROTEIN STRUCTURE, SECONDARY;

EID: 84865637729     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja305416a     Document Type: Article

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