Inhibiting the dimerization of HIV-1 protease

Synlett

Volumn , Issue 10, 1998, Pages 1040-1044

  Zutshi, Reena ^a   Shultz, Michael D ^a   Ulysse, Luckner ^a   Lutgring, Ray ^a   Bishop, Patricia ^a   Schweitzer, Barbara ^a   Vogel, Karen ^a   Franciskovich, Jeff ^a   Wilson, Matt ^a   Chmielewski, Jean ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0000439526     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-1854     Document Type: Article

References (28)

1. De Clercq, E. Pure and Appl. Chem. 1998, 70, 567.
2. Retroviral Proteases; Pearl, L. H., Ed.; McMillan Press, Basingstoke, UK; 1990.
3. a) Kohl, N. E.; Emini, E.; Schlief, W.; Davis, L.; Heimbach, J.; Dixon, R.; Scolnick, E.; Sigal, I. Proc. Natl. Acad. Sci. 1988, 85, 4686.
4. b) Le Grice, S. F.; Mills, J.; Mous, J. EMBO J. 1988, 7, 2547.
5. a) Wlodawer, A.; Vondrasek, J. Annu. Rev. Biophys. Biomol. Struct. 1998, 27, 249.
6. b) Kempf, D. J.; Sham, H. L. Curr. Phar. Des. 1996, 2, 225.
7. c) Tomasselli, A. G.; Thaisrivongs, S.; Heinrikson, R. L. Adv. Antiviral Drug Des. 1996, 2, 173.
8. Deeks, S. G.; Smith, M.; Holodniy, M.; Kahn, J. O. J. Am. Med. Assoc. 1997, 227, 145.
9. Gustchina, A.; Weber, I. T. Proteins: Struct. Funct. Genetics 1991, 10, 325.
10. Wlodawer, A.; Miller, A.; Jaskolski, M.; Sathyanarayana, B.; Baldwin, E.; Weber, I.; Selk, L.; Clawson, L.; Schneider, J.; Kent, S. Science 1989, 245, 616.
11. a) Darke, P. L.; Jordan, S. P.; Hall, D. L.; Zugay, J. A.; Shafer, J. A.; Kuo, L. C. Biochemistry 1994, 33, 98.
12. b) Kuzmic, P. Biochem. Biophys. Res. Comm. 1993, 191, 998.
13. c) Kuzmic, P.; Garcia-Echeverria, C.; Rich, D. H. Biochem. Biophys. Res. Comm. 1993, 191, 301.
14. d) Grant, S. K.; Deckman, I. C.; Culp, J. S.; Minnich, M. D.; Brooks, I. S.; Hensley, P.; Debouck, C.; Meek, T. D. Biochemistry 1992, 31, 9491.
15. e) Zhang, Z.-Y.; Poorman, R. A.; Maggiora, L. L.; Heinrikson, R. L.; Kezdy, F. J. J. Biol. Chem. 1991, 266, 15591.
16. (f) Cheng, Y.-S. E.; Yin, R H.; Foundling, S.; Blomstrom, D.; Kettner, C. A. Proc. Natl. Acad. Sci. USA 1990, 87, 9660.
17. Zutshi, R.; Brickner, M.; Chmielewski, J. Current Opinion in Chemical Biology 1998, 2, 62.
18. Franciskovich, J; Houseman, K.; Mueller, R.; Chmielewski J. Bioorganic and Med. Chem. Lett. 1993, 3, 739.
19. Zutshi, R.; Franciskovich, J.; Shultz, M.; Schweitzer, B.; Bishop, P.; Wilson, M.; Chmielewski, J. J. Am. Chem. Soc. 1997, 119, 4841.
20. Wang, S. S. J. Am. Chem Soc. 1973, 95, 1328.
21. Atherton, E.; Sheppard, R. C. The Peptides; Academic Press: New York, Vol.9, 1987.
22. Toth, M. V.; Marshall, G. R. Int. J. Peptide Protein Res. 1990, 36, 544.
23. a) Jeff Franciskovich, M. S. Thesis, Purdue University, 1992.
24. b) Ray Lutgring, Ph. D. Thesis, Purdue University, 1995.
25. Ulysse, L.; Chmielewski, J. Bioorg. Med. Chem. Lett. 1998, submitted.
26. Mohamadi, F.; Richards, N.; Guida, W.; Liskamp, R.; Lipton, M.; Caufield, C.; Chang, G.; Hendrickson, T.; Still, W. C.; J. Comp. Chem. 1990, 11, 440.
27. Shultz, M. D.; Chmielewski, J. Tetrahedron Asymmetry 1997, 8, 3881.
28. Karen Vogel, Ph. D. Thesis, Purdue University, 1995.