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Volumn 24, Issue 1, 2004, Pages 27-36

Paclitaxel-induced Apoptosis May Occur without A Prior G 2/M-Phase Arrest

Author keywords

Apoptosis; I B ; Mitotic arrest; NF B; Paclitaxel

Indexed keywords

BACCATIN III; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PACLITAXEL; PARTHENOLIDE;

EID: 1442350558     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (39)

References (34)
  • 2
    • 0015211527 scopus 로고
    • Plant antitumor agents: VI. The isolation and structure of Taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
    • Wani MC, Taylor HL, Wall ME et al: Plant antitumor agents: VI. The isolation and structure of Taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J Am Chem Soc 93: 23-25, 1971.
    • (1971) J Am Chem Soc , vol.93 , pp. 23-25
    • Wani, M.C.1    Taylor, H.L.2    Wall, M.E.3
  • 4
    • 0018387446 scopus 로고
    • Promotion of microtubule assembly in vitro by taxol
    • Schiff PB, Fant J and Horwitz SB: Promotion of microtubule assembly in vitro by taxol. Nature 22: 665-667, 1979.
    • (1979) Nature , vol.22 , pp. 665-667
    • Schiff, P.B.1    Fant, J.2    Horwitz, S.B.3
  • 5
    • 0019805521 scopus 로고
    • Taxol induced polymerization of purified tubulin. Mechanism of action
    • Kuman N: Taxol induced polymerization of purified tubulin. Mechanism of action. J Biol Chem 256: 10435-10441, 1981.
    • (1981) J Biol Chem , vol.256 , pp. 10435-10441
    • Kuman, N.1
  • 6
    • 0023809123 scopus 로고
    • Microtubule changes and cytotoxicity in leukemia cell lines treated with taxol
    • Rowinsky EK, Donehower RC, Jones RJ and Tucker RW: Microtubule changes and cytotoxicity in leukemia cell lines treated with taxol. Cancer Res 48: 4093-4100, 1988.
    • (1988) Cancer Res , vol.48 , pp. 4093-4100
    • Rowinsky, E.K.1    Donehower, R.C.2    Jones, R.J.3    Tucker, R.W.4
  • 7
    • 0026516994 scopus 로고
    • Mechanism of action of Taxol
    • Horwitz SB: Mechanism of action of Taxol. Trends Pharmacol Sci 13: 134-136: 1992.
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 134-136
    • Horwitz, S.B.1
  • 8
    • 0021229643 scopus 로고
    • Taxol: An antimitotic agent with a new mechanism of action
    • Manfredi JJ and Horwitz SB: Taxol: an antimitotic agent with a new mechanism of action. Pharmac Ther 25: 83-125, 1984.
    • (1984) Pharmac Ther , vol.25 , pp. 83-125
    • Manfredi, J.J.1    Horwitz, S.B.2
  • 9
    • 0018188876 scopus 로고
    • Cytologic evidence that Paclitaxel, an antineoplastic agent from Taxus brevifolia, acts as a mitotic spindle poison
    • Fuchs DA and Johnson RK: Cytologic evidence that Paclitaxel, an antineoplastic agent from Taxus brevifolia, acts as a mitotic spindle poison. Cancer Treatment Rept 62: 1219, 1978.
    • (1978) Cancer Treatment Rept , vol.62 , pp. 1219
    • Fuchs, D.A.1    Johnson, R.K.2
  • 10
    • 0027196777 scopus 로고
    • Paclitaxel induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells
    • Bhalla K, Ibrado A, Tourhina E, Tang C, Mahonery ME and Huang Y: Paclitaxel induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells. Leukemia 7: 563-568, 1993.
    • (1993) Leukemia , vol.7 , pp. 563-568
    • Bhalla, K.1    Ibrado, A.2    Tourhina, E.3    Tang, C.4    Mahonery, M.E.5    Huang, Y.6
  • 11
    • 0000834631 scopus 로고
    • Glucocorticoid-mediated inhibition of Paclitaxel-induced apoptosis in leiomyosarcoma cells
    • Fan W, Everett ET, Tang C, Cooper T, Fang Q, Bhalla K and Norris JS: Glucocorticoid-mediated inhibition of Paclitaxel-induced apoptosis in leiomyosarcoma cells. Cell Pharm 1: 205-212, 1994.
    • (1994) Cell Pharm , vol.1 , pp. 205-212
    • Fan, W.1    Everett, E.T.2    Tang, C.3    Cooper, T.4    Fang, Q.5    Bhalla, K.6    Norris, J.S.7
  • 12
    • 0000881538 scopus 로고
    • Characterizations of Paclitaxel-induced apoptosis and altered gene expression in human breast cancer cells
    • Cheng L, Zheng S, Raghunathan K, Priest DG, Willingham MC, Norris JS and Fan W: Characterizations of Paclitaxel-induced apoptosis and altered gene expression in human breast cancer cells. Cell Pharm 2: 249-257, 1995.
    • (1995) Cell Pharm , vol.2 , pp. 249-257
    • Cheng, L.1    Zheng, S.2    Raghunathan, K.3    Priest, D.G.4    Willingham, M.C.5    Norris, J.S.6    Fan, W.7
  • 13
    • 0027968951 scopus 로고
    • Evidence for involvement of tyrosine phosphorylation in paclitaxel-induced apoptosis in human ovarian tumor cell line
    • Liu Y, Bhalla K, Hill C and Priest DG: Evidence for involvement of tyrosine phosphorylation in paclitaxel-induced apoptosis in human ovarian tumor cell line. Biochem Pharmacol 48: 1265-1272, 1995.
    • (1995) Biochem Pharmacol , vol.48 , pp. 1265-1272
    • Liu, Y.1    Bhalla, K.2    Hill, C.3    Priest, D.G.4
  • 14
    • 0034662496 scopus 로고    scopus 로고
    • Nuclear factor-κB/IκB signaling pathway may contribute to the mediation of paclitaxel-induced apoptosis in solid tumor cells
    • Huang Y, Johnson RK, Norris JS and Fan W: Nuclear factor-κ B/IκB signaling pathway may contribute to the mediation of paclitaxel-induced apoptosis in solid tumor cells. Cancer Res 60: 4426-4432, 2000.
    • (2000) Cancer Res , vol.60 , pp. 4426-4432
    • Huang, Y.1    Johnson, R.K.2    Norris, J.S.3    Fan, W.4
  • 15
    • 0034920013 scopus 로고    scopus 로고
    • Selective potentiation of paclitaxel (Taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines
    • Mcdaid HM and Horwitz SB: Selective potentiation of paclitaxel (Taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines. Mol Phamacol 60: 908-918, 2001.
    • (2001) Mol Phamacol , vol.60 , pp. 908-918
    • Mcdaid, H.M.1    Horwitz, S.B.2
  • 16
    • 0035377357 scopus 로고    scopus 로고
    • Paclitaxel induces prolonged activation of Ra/MEK/ERK pathway independently of activation of programmed cell death machinery
    • Okano J and Rustgi AK: Paclitaxel induces prolonged activation of Ra/MEK/ERK pathway independently of activation of programmed cell death machinery. J Biol Chem 22: 19555-19564, 2001.
    • (2001) J Biol Chem , vol.22 , pp. 19555-19564
    • Okano, J.1    Rustgi, A.K.2
  • 17
    • 0027360552 scopus 로고
    • Mechanism of mitotic block and inhibition of cell proliferation by Taxol at low concentrations
    • Jordan MA, Toso RJ, Thrower D and Wilson L: Mechanism of mitotic block and inhibition of cell proliferation by Taxol at low concentrations. Proc Natl Acad Sci USA 90: 9552-9556, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9552-9556
    • Jordan, M.A.1    Toso, R.J.2    Thrower, D.3    Wilson, L.4
  • 18
    • 0030020158 scopus 로고    scopus 로고
    • Mitotic block induced in Hela cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
    • Jordan MA, Wendell K, Gardiner S, Derry WB, Copp H and Wilson L: Mitotic block induced in Hela cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res 56: 816-825, 1996.
    • (1996) Cancer Res , vol.56 , pp. 816-825
    • Jordan, M.A.1    Wendell, K.2    Gardiner, S.3    Derry, W.B.4    Copp, H.5    Wilson, L.6
  • 19
    • 0032529464 scopus 로고    scopus 로고
    • Mechanisms of paclitaxel-induced cell death are concentration dependent
    • Torres KE and Horwitz SB: Mechanisms of paclitaxel-induced cell death are concentration dependent. Cancer Res 58: 3620-3626, 1998.
    • (1998) Cancer Res , vol.58 , pp. 3620-3626
    • Torres, K.E.1    Horwitz, S.B.2
  • 20
    • 0030737921 scopus 로고    scopus 로고
    • Dual cytotoxic mechanisms of submicromolar Paclitaxel on human leukemia HL-60 cells
    • Lieu CH, Chang YN and Lai YK: Dual cytotoxic mechanisms of submicromolar Paclitaxel on human leukemia HL-60 cells. Biochem Pharmacol 53: 1587-1596, 1997.
    • (1997) Biochem Pharmacol , vol.53 , pp. 1587-1596
    • Lieu, C.H.1    Chang, Y.N.2    Lai, Y.K.3
  • 21
    • 0036006698 scopus 로고    scopus 로고
    • IκB kinase activation is involved in regulation of Paclitaxel-induced apoptosis in human tumor cell lines
    • Huang Y and Fan W: IκB kinase activation is involved in regulation of Paclitaxel-induced apoptosis in human tumor cell lines. Mol Pharm 61: 105-113, 2002.
    • (2002) Mol Pharm , vol.61 , pp. 105-113
    • Huang, Y.1    Fan, W.2
  • 23
    • 0001510940 scopus 로고    scopus 로고
    • Glucocorticoids selectively inhibit Paclitaxel-induced apoptosis in a human breast cancer cell line
    • Fan W, Cheng LR, Norris JS and Willingham MC: Glucocorticoids selectively inhibit Paclitaxel-induced apoptosis in a human breast cancer cell line. Cell Pharm 3: 435-440, 1996.
    • (1996) Cell Pharm , vol.3 , pp. 435-440
    • Fan, W.1    Cheng, L.R.2    Norris, J.S.3    Willingham, M.C.4
  • 24
    • 0000521925 scopus 로고    scopus 로고
    • Glucocorticoids modulate taxol cytotoxicity in human solid tumor cells
    • Fan W, Schandl CA, Cheng L, Norris JS and Willingham MC: Glucocorticoids modulate taxol cytotoxicity in human solid tumor cells. Cell Pharm 3: 343-348, 1996.
    • (1996) Cell Pharm , vol.3 , pp. 343-348
    • Fan, W.1    Schandl, C.A.2    Cheng, L.3    Norris, J.S.4    Willingham, M.C.5
  • 25
    • 0036357501 scopus 로고    scopus 로고
    • The possible correlation between activation of NF-κB/IκB pathway and the susceptibility of tumor cells to Paclitaxel-induced apoptosis
    • Huang Y, Fang Y, Dziadyk JM, Norris JS and Fan W: The possible correlation between activation of NF-κB/IκB pathway and the susceptibility of tumor cells to Paclitaxel-induced apoptosis. Oncol Res/Anti-Cancer Drug Design 13: 113-122, 2002.
    • (2002) Oncol Res/Anti-Cancer Drug Design , vol.13 , pp. 113-122
    • Huang, Y.1    Fang, Y.2    Dziadyk, J.M.3    Norris, J.S.4    Fan, W.5
  • 26
    • 0027462682 scopus 로고
    • Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκB-α
    • Brown K, Park S, Kanno T, Franzoso G and Siebenlist U: Mutual regulation of the transcriptional activator NF-κB and its inhibitor, IκB-α. Proc Natl Acad Sci USA 90: 2532-2536, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2532-2536
    • Brown, K.1    Park, S.2    Kanno, T.3    Franzoso, G.4    Siebenlist, U.5
  • 27
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • Baldwin AS Jr: The NF-κB and IκB proteins: new discoveries and insights. Ann Rev Immunol 14: 649-683, 1996.
    • (1996) Ann Rev Immunol , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 28
    • 0024294357 scopus 로고
    • Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor
    • Baeuerle P and Baltimore D: Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor. Cell 53: 211-217, 1988.
    • (1988) Cell , vol.53 , pp. 211-217
    • Baeuerle, P.1    Baltimore, D.2
  • 29
    • 0030026562 scopus 로고
    • Both amino- and carboxyl-terminal sequences within IκBα regulate its inducible degradation
    • Sun S, Elwood J and Greene WC: Both amino- and carboxyl-terminal sequences within IκBα regulate its inducible degradation. Mol Cell Biol 16: 1058-1065, 1995.
    • (1995) Mol Cell Biol , vol.16 , pp. 1058-1065
    • Sun, S.1    Elwood, J.2    Greene, W.C.3
  • 30
    • 0033596127 scopus 로고    scopus 로고
    • Control of apoptosis by Rel/NF-κB transcription factor
    • Barkett M and Gilmore TD: Control of apoptosis by Rel/NF-κB transcription factor. Oncogene 22: 6910-6924, 2000.
    • (2000) Oncogene , vol.22 , pp. 6910-6924
    • Barkett, M.1    Gilmore, T.D.2
  • 31
  • 32
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F and Riccardi C: A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 139: 271-279, 1991.
    • (1991) J Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 33
    • 0343765810 scopus 로고    scopus 로고
    • Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-κB
    • Bork PM, Schmitz ML, Kuhnt M, Escher C and Heinrich M: Sesquiterpene lactone containing Mexican Indian medicinal plants and pure sesquiterpene lactones as potent inhibitors of transcription factor NF-κB. FEBS Lett 402: 85-90, 1997.
    • (1997) FEBS Lett , vol.402 , pp. 85-90
    • Bork, P.M.1    Schmitz, M.L.2    Kuhnt, M.3    Escher, C.4    Heinrich, M.5
  • 34
    • 0031915368 scopus 로고    scopus 로고
    • Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta
    • Hehner SP, Heinrich M, Bork PM, Vogt M, Ratter F, Lehmann V, Schulze-Osthoff K, Droge W and Schmitz ML: Sesquiterpene lactones specifically inhibit activation of NF-kappa B by preventing the degradation of I kappa B-alpha and I kappa B-beta. J Biol Chem 273: 1288-1297, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 1288-1297
    • Hehner, S.P.1    Heinrich, M.2    Bork, P.M.3    Vogt, M.4    Ratter, F.5    Lehmann, V.6    Schulze-Osthoff, K.7    Droge, W.8    Schmitz, M.L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.