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Volumn 3, Issue 6, 2007, Pages 805-817

Drug resistance in cancer - Searching for mechanisms, markers and therapeutic agents

Author keywords

Cancer chemotherapy; Drug resistance; Multiple drug resistance; Targeted therapy; Tyrosine kinase

Indexed keywords

4 [N (2 HYDROXYETHYL) N [2 (3 INDOLYL)ETHYL]AMINOMETHYL]CINNAMOHYDROXAMIC ACID; ANTHRACYCLINE; BEVACIZUMAB; BORTEZOMIB; BREAST CANCER RESISTANCE PROTEIN; CETUXIMAB; CISPLATIN; DASATINIB; DIHYDROFOLIC ACID; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERLOTINIB; FLUOROURACIL; GEFITINIB; GLYCOPROTEIN P; IMATINIB; LAPATINIB; LENALIDOMIDE; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; PROTEIN TYROSINE KINASE INHIBITOR; SORAFENIB; SUNITINIB; TAMOXIFEN; TRASTUZUMAB; UNINDEXED DRUG; VATALANIB; VERAPAMIL; VINCA ALKALOID; VINCRISTINE; XENOBIOTIC AGENT;

EID: 37349021709     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425255.3.6.805     Document Type: Review
Times cited : (57)

References (103)
  • 1
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • DEAN M, FOJO T, BATES S: Tumour stem cells and drug resistance. Nat. Rev. Cancer (2005) 5(4):275-284.
    • (2005) Nat. Rev. Cancer , vol.5 , Issue.4 , pp. 275-284
    • DEAN, M.1    FOJO, T.2    BATES, S.3
  • 2
    • 0030844320 scopus 로고    scopus 로고
    • The multidrug-resistant human lung tumour cell line, DLKP-A10, expresses novel drug accumulation and sequestration systems
    • CLEARY I, DOHERTY G, MORAN E, CLYNES M: The multidrug-resistant human lung tumour cell line, DLKP-A10, expresses novel drug accumulation and sequestration systems. Biochem. Pharmacol. (1997) 53(10):1493-1502.
    • (1997) Biochem. Pharmacol , vol.53 , Issue.10 , pp. 1493-1502
    • CLEARY, I.1    DOHERTY, G.2    MORAN, E.3    CLYNES, M.4
  • 3
    • 33747288211 scopus 로고    scopus 로고
    • Cellular functions of vaults and their involvement in multidrug resistance
    • STEINER E, HOLZMANN K, ELBLING L, MICKSCHE M, BERGER W: Cellular functions of vaults and their involvement in multidrug resistance. Curr. Drug Targets (2006) 7(8):923-934.
    • (2006) Curr. Drug Targets , vol.7 , Issue.8 , pp. 923-934
    • STEINER, E.1    HOLZMANN, K.2    ELBLING, L.3    MICKSCHE, M.4    BERGER, W.5
  • 4
    • 33745615832 scopus 로고    scopus 로고
    • Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas
    • CHEN KG, VALENCIA JC, LAI B et al.: Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas. Proc. Natl. Acad. Sci. USA (2006) 103(26):9903-9907.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , Issue.26 , pp. 9903-9907
    • CHEN, K.G.1    VALENCIA, J.C.2    LAI, B.3
  • 5
    • 0030915004 scopus 로고    scopus 로고
    • Isolation from a human MDR lung cell line of multiple clonal subpopulations which exhibit significantly different drug resistance
    • HEENAN M, O'DRISCOLL L, CLEARY I, CONNOLLY I, CLYNES M: Isolation from a human MDR lung cell line of multiple clonal subpopulations which exhibit significantly different drug resistance. Int. J. Cancer (1997) 71(5):907-915.
    • (1997) Int. J. Cancer , vol.71 , Issue.5 , pp. 907-915
    • HEENAN, M.1    O'DRISCOLL, L.2    CLEARY, I.3    CONNOLLY, I.4    CLYNES, M.5
  • 6
    • 33751263449 scopus 로고    scopus 로고
    • A Phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer
    • O'CONNOR R, O'LEARY M, BALLOT J et al.: A Phase I clinical and pharmacokinetic study of the multi-drug resistance protein-1 (MRP-1) inhibitor sulindac, in combination with epirubicin in patients with advanced cancer. Cancer Chemother. Pharmacol. (2007) 59(1):79-87.
    • (2007) Cancer Chemother. Pharmacol , vol.59 , Issue.1 , pp. 79-87
    • O'CONNOR, R.1    O'LEARY, M.2    BALLOT, J.3
  • 7
    • 0036881871 scopus 로고    scopus 로고
    • ABC transporters and inhibitors: New targets, new agents
    • LEONARD GD. POLGAR O, BATES SE: ABC transporters and inhibitors: new targets, new agents. Curr. Opin. Investig. Drugs (2002) 3(11):1652-1659.
    • (2002) Curr. Opin. Investig. Drugs , vol.3 , Issue.11 , pp. 1652-1659
    • LEONARD, G.D.1    POLGAR, O.2    BATES, S.E.3
  • 8
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • JULIANO RL, LING V: A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim. Biopbys. Acta (1976) 455(1):152-162.
    • (1976) Biochim. Biopbys. Acta , vol.455 , Issue.1 , pp. 152-162
    • JULIANO, R.L.1    LING, V.2
  • 9
    • 31844448665 scopus 로고    scopus 로고
    • The translocation mechanism of P-glycoprotein
    • CALLAGHAN R, FORD RC, KERR ID: The translocation mechanism of P-glycoprotein. FEBS Lett. (2006) 580(4):1056-1063.
    • (2006) FEBS Lett , vol.580 , Issue.4 , pp. 1056-1063
    • CALLAGHAN, R.1    FORD, R.C.2    KERR, I.D.3
  • 10
    • 20444393495 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitor resistance in cancer: Role of ABC multidrug transporters
    • OZVEGY-LACZKA C, CSEREPES J, ELKIND NB, SARKADI B: Tyrosine kinase inhibitor resistance in cancer: role of ABC multidrug transporters. Drug Resist. Updat. (2005) 8(1-2):15-26.
    • (2005) Drug Resist. Updat , vol.8 , Issue.1-2 , pp. 15-26
    • OZVEGY-LACZKA, C.1    CSEREPES, J.2    ELKIND, N.B.3    SARKADI, B.4
  • 11
    • 0027095653 scopus 로고
    • Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
    • COLE SP, BHARDWAJ G, GERLACH J H et al.: Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science (1992) 258(5088):1650-1654.
    • (1992) Science , vol.258 , Issue.5088 , pp. 1650-1654
    • COLE, S.P.1    BHARDWAJ, G.2    GERLACH, J.H.3
  • 14
    • 33846681607 scopus 로고    scopus 로고
    • Multidrug resistance-associated proteins 3, 4, and 5
    • BORST P, DE WOLF C, VAN DE WETERING K: Multidrug resistance-associated proteins 3, 4, and 5. Pflugers Arch. (2007) 453(5):661-673.
    • (2007) Pflugers Arch , vol.453 , Issue.5 , pp. 661-673
    • BORST, P.1    DE WOLF, C.2    VAN DE WETERING, K.3
  • 15
    • 31844440738 scopus 로고    scopus 로고
    • Membrane topology of human ABC proteins
    • TUSNADY GE, SARKADI B, SIMON I, VARADI A: Membrane topology of human ABC proteins. FEBS Lett. (2006) 580(4):1017-1022.
    • (2006) FEBS Lett , vol.580 , Issue.4 , pp. 1017-1022
    • TUSNADY, G.E.1    SARKADI, B.2    SIMON, I.3    VARADI, A.4
  • 17
    • 33745897902 scopus 로고    scopus 로고
    • Transport of glutathione and glutathione conjugates by MRP1
    • COLE SP, DEELEY RG: Transport of glutathione and glutathione conjugates by MRP1. Trends Pharmacol. Sci. (2006) 27(8):438-446.
    • (2006) Trends Pharmacol. Sci , vol.27 , Issue.8 , pp. 438-446
    • COLE, S.P.1    DEELEY, R.G.2
  • 18
    • 0037362355 scopus 로고    scopus 로고
    • ATP binding cassette transporters and drug resistance in breast cancer
    • LEONESSA F, CLARKE R: ATP binding cassette transporters and drug resistance in breast cancer. Endocr. Relat. Cancer (2003) 10(1):43-73.
    • (2003) Endocr. Relat. Cancer , vol.10 , Issue.1 , pp. 43-73
    • LEONESSA, F.1    CLARKE, R.2
  • 19
    • 33745736603 scopus 로고    scopus 로고
    • Multidrug resistance: Retrospect and prospects in anti-cancer drug treatment
    • PEREZ-TOMAS R: Multidrug resistance: retrospect and prospects in anti-cancer drug treatment. Curr. Med. Chem. (2006) 13(16):1859-1876.
    • (2006) Curr. Med. Chem , vol.13 , Issue.16 , pp. 1859-1876
    • PEREZ-TOMAS, R.1
  • 20
    • 2342431730 scopus 로고    scopus 로고
    • Intractable cancers: The many faces of multidrug resistance and the many targets it presents for therapeutic attack
    • STEIN WD, BATES SE, FOJO T: Intractable cancers: the many faces of multidrug resistance and the many targets it presents for therapeutic attack. Curr. Drug Targets (2004) 5(4):333-346.
    • (2004) Curr. Drug Targets , vol.5 , Issue.4 , pp. 333-346
    • STEIN, W.D.1    BATES, S.E.2    FOJO, T.3
  • 21
    • 28544432478 scopus 로고    scopus 로고
    • Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs
    • BAKER EK, JOHNSTONE RW, ZALCBERG JR, EL-OSTA A: Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs. Oncogene (2005) 24(54):8061-8075.
    • (2005) Oncogene , vol.24 , Issue.54 , pp. 8061-8075
    • BAKER, E.K.1    JOHNSTONE, R.W.2    ZALCBERG, J.R.3    EL-OSTA, A.4
  • 22
    • 0141888537 scopus 로고    scopus 로고
    • The role of ABC transporters in clinical practice
    • LEONARD GD, FOJO T, BATES SE: The role of ABC transporters in clinical practice. Oncologist (2003) 8(5):411-424.
    • (2003) Oncologist , vol.8 , Issue.5 , pp. 411-424
    • LEONARD, G.D.1    FOJO, T.2    BATES, S.E.3
  • 23
    • 23644452472 scopus 로고    scopus 로고
    • Phase II study of tariquidar, a selective P-glycoprotein inhibitor, in patients with chemotherapy-resistant, advanced breast carcinoma
    • PUSZTAI L, WAGNER P, IBRAHIM N et al.: Phase II study of tariquidar, a selective P-glycoprotein inhibitor, in patients with chemotherapy-resistant, advanced breast carcinoma. Cancer (2005) 104(4):682-691.
    • (2005) Cancer , vol.104 , Issue.4 , pp. 682-691
    • PUSZTAI, L.1    WAGNER, P.2    IBRAHIM, N.3
  • 24
    • 28944432804 scopus 로고    scopus 로고
    • Multidrug resistance/P-glycoprotein and breast cancer review and meta-analysis
    • CLARKE R, LEONESSA F, TROCK B: Multidrug resistance/P-glycoprotein and breast cancer review and meta-analysis. Semin. Oncol. (2005) 32(6 Suppl. 7):S9-S15.
    • (2005) Semin. Oncol , vol.32 , Issue.6 SUPPL. 7
    • CLARKE, R.1    LEONESSA, F.2    TROCK, B.3
  • 25
    • 34249324102 scopus 로고    scopus 로고
    • The pharmacology of cancer resistance
    • 3A:1267-1272
    • O'CONNOR R: The pharmacology of cancer resistance. Anticancer Res. (2007) 27(3A):1267-1272.
    • (2007) Anticancer Res , vol.27
    • O'CONNOR, R.1
  • 26
    • 0242469240 scopus 로고    scopus 로고
    • Organic anion-transporting polypeptide (OATP) transporter family and drug disposition
    • KIM RB: Organic anion-transporting polypeptide (OATP) transporter family and drug disposition. Eur. J. Clin. Invest. (2003) 33(Suppl. 2):1-5.
    • (2003) Eur. J. Clin. Invest , vol.33 , Issue.SUPPL. 2 , pp. 1-5
    • KIM, R.B.1
  • 27
    • 25144491657 scopus 로고    scopus 로고
    • Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel
    • SMITH NF, ACHARYA MR, DESAI N, FIGG WD, SPARREBOOM A: Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel. Cancer Biol. Ther. (2005) 4(8):815-818.
    • (2005) Cancer Biol. Ther , vol.4 , Issue.8 , pp. 815-818
    • SMITH, N.F.1    ACHARYA, M.R.2    DESAI, N.3    FIGG, W.D.4    SPARREBOOM, A.5
  • 28
    • 33646777774 scopus 로고    scopus 로고
    • Dinuclear alkylamine platinum(II) complexes of [1,2-bis(4-fluorophenyl)ethylenediamine] platinum(II): Influence of endocytosis and copper and organic cation transport systems on cellular uptake
    • KAPP T, MULLER S, GUST R. Dinuclear alkylamine platinum(II) complexes of [1,2-bis(4-fluorophenyl)ethylenediamine] platinum(II): influence of endocytosis and copper and organic cation transport systems on cellular uptake. ChemMedChem (2006) 1(5):560-564.
    • (2006) ChemMedChem , vol.1 , Issue.5 , pp. 560-564
    • KAPP, T.1    MULLER, S.2    GUST, R.3
  • 29
    • 2442638219 scopus 로고    scopus 로고
    • Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells
    • SU Y, ZHANG X, SINKO PJ: Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells. Mol. Pharm. (2004) 1(1):49-56.
    • (2004) Mol. Pharm , vol.1 , Issue.1 , pp. 49-56
    • SU, Y.1    ZHANG, X.2    SINKO, P.J.3
  • 30
    • 0345700691 scopus 로고    scopus 로고
    • Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma
    • CUI Y, KONIG J, NIES AT et al.: Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma. Lab. Invest. (2003) 83(4):527-538.
    • (2003) Lab. Invest , vol.83 , Issue.4 , pp. 527-538
    • CUI, Y.1    KONIG, J.2    NIES, A.T.3
  • 31
  • 32
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • SLAMON DJ, CLARK GM, WONG SG, LEVIN WJ, ULLRICH A, MCGUIRE WL: Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (1987) 235(4785):177-182.
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • SLAMON, D.J.1    CLARK, G.M.2    WONG, S.G.3    LEVIN, W.J.4    ULLRICH, A.5    MCGUIRE, W.L.6
  • 33
    • 33846627223 scopus 로고    scopus 로고
    • Progress and new standards of care in the management of HER-2 positive breast cancer
    • DEMONTY G, BERNARD-MARTY C, PUGLISI F, MANCINI I, PICCART M: Progress and new standards of care in the management of HER-2 positive breast cancer. Eur. J. Cancer (2007) 43(3):497-509.
    • (2007) Eur. J. Cancer , vol.43 , Issue.3 , pp. 497-509
    • DEMONTY, G.1    BERNARD-MARTY, C.2    PUGLISI, F.3    MANCINI, I.4    PICCART, M.5
  • 34
    • 33845886440 scopus 로고    scopus 로고
    • Lapatinib plus capecitabine for HER2-positiveadvanced breast cancer
    • GEYER CE, FORSTER J, LINDQUIST D et al.: Lapatinib plus capecitabine for HER2-positiveadvanced breast cancer. N. Engl. J. Med. (2006) 355(26):2733-2743.
    • (2006) N. Engl. J. Med , vol.355 , Issue.26 , pp. 2733-2743
    • GEYER, C.E.1    FORSTER, J.2    LINDQUIST, D.3
  • 35
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • LYNCH TJ, BELL DW, SORDELLA R et al.: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. (2004) 350(21):2129-2139.
    • (2004) N. Engl. J. Med , vol.350 , Issue.21 , pp. 2129-2139
    • LYNCH, T.J.1    BELL, D.W.2    SORDELLA, R.3
  • 36
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • PAEZ JG, JANNE PA, LEE JC et al.: EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science (2004) 304(5676):1497-1500.
    • (2004) Science , vol.304 , Issue.5676 , pp. 1497-1500
    • PAEZ, J.G.1    JANNE, P.A.2    LEE, J.C.3
  • 37
    • 33745738260 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: From the biology to the clinic
    • RANIERI G, PATRUNO R, RUGGIERI E, MONTEMURRO S, VALERIO P, RIBATTI D: Vascular endothelial growth factor (VEGF) as a target of bevacizumab in cancer: from the biology to the clinic. Curr. Med. Chem. (2006) 13(16):1845-1857.
    • (2006) Curr. Med. Chem , vol.13 , Issue.16 , pp. 1845-1857
    • RANIERI, G.1    PATRUNO, R.2    RUGGIERI, E.3    MONTEMURRO, S.4    VALERIO, P.5    RIBATTI, D.6
  • 38
    • 12244301581 scopus 로고    scopus 로고
    • In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
    • MENDEL DB, LAIRD AD, XIN X et al.: In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin. Cancer Res. (2003) 9(1):327-337.
    • (2003) Clin. Cancer Res , vol.9 , Issue.1 , pp. 327-337
    • MENDEL, D.B.1    LAIRD, A.D.2    XIN, X.3
  • 39
    • 4944249117 scopus 로고    scopus 로고
    • BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
    • WILHELM SM, CARTER C, TANG L et al.: BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. (2004) 64(19):7099-7109.
    • (2004) Cancer Res , vol.64 , Issue.19 , pp. 7099-7109
    • WILHELM, S.M.1    CARTER, C.2    TANG, L.3
  • 40
    • 19944428353 scopus 로고    scopus 로고
    • Discovery of N- (2-chloro-6-methyl-phenyl)- 2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2- methylpyrimidin-4-ylamino) thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays
    • LOMBARDO LJ, LEE FY, CHEN P et al.: Discovery of N- (2-chloro-6-methyl-phenyl)- 2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2- methylpyrimidin-4-ylamino) thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. J. Med. Chem. (2004) 47 (27):6658-6661.
    • (2004) J. Med. Chem , vol.47 , Issue.27 , pp. 6658-6661
    • LOMBARDO, L.J.1    LEE, F.Y.2    CHEN, P.3
  • 41
    • 25144450089 scopus 로고    scopus 로고
    • Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps
    • BURGER H, VAN TOL H, BROK M et al.: Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps. Cancer Biol. Ther. (2005) 4(7):747-752.
    • (2005) Cancer Biol. Ther , vol.4 , Issue.7 , pp. 747-752
    • BURGER, H.1    VAN TOL, H.2    BROK, M.3
  • 42
    • 9444282642 scopus 로고    scopus 로고
    • Active transport of imatinib into and out of cells: Implications for drug resistance
    • THOMAS J, WANG L, CLARK RE, PIRMOHAMED M: Active transport of imatinib into and out of cells: implications for drug resistance. Blood (2004) 104(12):3739-3745.
    • (2004) Blood , vol.104 , Issue.12 , pp. 3739-3745
    • THOMAS, J.1    WANG, L.2    CLARK, R.E.3    PIRMOHAMED, M.4
  • 44
    • 33646404611 scopus 로고    scopus 로고
    • Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo
    • LEGGAS M, PANETTA JC, ZHUANG Y et al.: Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo. Cancer Res. (2006) 66(9):4802-4807.
    • (2006) Cancer Res , vol.66 , Issue.9 , pp. 4802-4807
    • LEGGAS, M.1    PANETTA, J.C.2    ZHUANG, Y.3
  • 46
    • 1242270612 scopus 로고    scopus 로고
    • Acquired resistance to EGFR inhibitors: Mechanisms and prevention strategies
    • VILORIA-PETIT AM, KERBEL RS: Acquired resistance to EGFR inhibitors: mechanisms and prevention strategies. Int. J. Radiat. Oncol. Biol. Phys. (2004) 58(3):914-926.
    • (2004) Int. J. Radiat. Oncol. Biol. Phys , vol.58 , Issue.3 , pp. 914-926
    • VILORIA-PETIT, A.M.1    KERBEL, R.S.2
  • 47
    • 15944404601 scopus 로고    scopus 로고
    • The development of imatinib as a therapeutic agent for chronic myeloid leukemia
    • DEININGER M, BUCHDUNGER E, DRUKER BJ: The development of imatinib as a therapeutic agent for chronic myeloid leukemia. Blood (2005) 105(7):2640-2653.
    • (2005) Blood , vol.105 , Issue.7 , pp. 2640-2653
    • DEININGER, M.1    BUCHDUNGER, E.2    DRUKER, B.J.3
  • 48
    • 33750595859 scopus 로고    scopus 로고
    • Molecular correlates of imatinib resistance in gastrointestinal stromal tumors
    • HEINRICH MC, CORLESS CL, BLANKE CD et al.: Molecular correlates of imatinib resistance in gastrointestinal stromal tumors. J. Clin. Oncol. (2006) 24(29):4764-4774.
    • (2006) J. Clin. Oncol , vol.24 , Issue.29 , pp. 4764-4774
    • HEINRICH, M.C.1    CORLESS, C.L.2    BLANKE, C.D.3
  • 49
    • 0344987881 scopus 로고    scopus 로고
    • A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
    • COOLS J, DEANGELO DJ, GOTLIB J et al.: A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N. Engl. J. Med. (2003) 348(13):1201-1214.
    • (2003) N. Engl. J. Med , vol.348 , Issue.13 , pp. 1201-1214
    • COOLS, J.1    DEANGELO, D.J.2    GOTLIB, J.3
  • 50
    • 19344364557 scopus 로고    scopus 로고
    • BCR-ABL gene amplification and overexpression in a patient with chronic myeloid leukemia treated with imatinib
    • GADZICKI D, VON NEUHOFF N, STEINEMANN D et al.: BCR-ABL gene amplification and overexpression in a patient with chronic myeloid leukemia treated with imatinib. Cancer Genet. Cytogenet. (2005) 159(2):164-167.
    • (2005) Cancer Genet. Cytogenet , vol.159 , Issue.2 , pp. 164-167
    • GADZICKI, D.1    VON NEUHOFF, N.2    STEINEMANN, D.3
  • 51
    • 15744372810 scopus 로고    scopus 로고
    • KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
    • PAO W, WANG TY, RIELY GJ et al.: KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med. (2005) 2(1):E17.
    • (2005) PLoS Med , vol.2 , Issue.1
    • PAO, W.1    WANG, T.Y.2    RIELY, G.J.3
  • 52
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • PAO W, MILLER V, ZAKOWSKI M et al.: EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc. Natl. Acad. Sci. USA (2004) 101(36):13306-13311.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.36 , pp. 13306-13311
    • PAO, W.1    MILLER, V.2    ZAKOWSKI, M.3
  • 53
    • 18244371651 scopus 로고    scopus 로고
    • Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
    • PAO W, MILLER VA, POLITI KA et al.: Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoSMed. (2005) 2(3):E73.
    • (2005) PLoSMed , vol.2 , Issue.3
    • PAO, W.1    MILLER, V.A.2    POLITI, K.A.3
  • 54
    • 33646228635 scopus 로고    scopus 로고
    • KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
    • LIEVRE A, BACHET JB, LE CORRE D et al.: KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res. (2006) 66(8):3992-3995.
    • (2006) Cancer Res , vol.66 , Issue.8 , pp. 3992-3995
    • LIEVRE, A.1    BACHET, J.B.2    LE CORRE, D.3
  • 55
    • 24344438558 scopus 로고    scopus 로고
    • Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity
    • PERERA RM, NARITA Y, FURNARI FB et al.: Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity. Clin. Cancer Res. (2005) 11(17):6390-6399.
    • (2005) Clin. Cancer Res , vol.11 , Issue.17 , pp. 6390-6399
    • PERERA, R.M.1    NARITA, Y.2    FURNARI, F.B.3
  • 56
    • 31644439702 scopus 로고    scopus 로고
    • Herceptin: Mechanisms of action and resistance
    • NAHTA R, ESTEVA FJ: Herceptin: mechanisms of action and resistance. Cancer Lett. (2006) 232(2):123-138.
    • (2006) Cancer Lett , vol.232 , Issue.2 , pp. 123-138
    • NAHTA, R.1    ESTEVA, F.J.2
  • 57
    • 2542526069 scopus 로고    scopus 로고
    • NAHTA R, TAKAHASHI T, UENO NT HUNG MC, ESTEVA FJ: P27(kip 1) down-regulation is associated with trastuzumab resistance in breast cancer cells. Cancer Res. (2004) 64(11):3981-3986.
    • NAHTA R, TAKAHASHI T, UENO NT HUNG MC, ESTEVA FJ: P27(kip 1) down-regulation is associated with trastuzumab resistance in breast cancer cells. Cancer Res. (2004) 64(11):3981-3986.
  • 58
    • 5144226211 scopus 로고    scopus 로고
    • PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
    • NAGATA Y, LAN KH, ZHOU X et al.: PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell (2004) 6(2):117-127.
    • (2004) Cancer Cell , vol.6 , Issue.2 , pp. 117-127
    • NAGATA, Y.1    LAN, K.H.2    ZHOU, X.3
  • 59
    • 0346154748 scopus 로고    scopus 로고
    • Molecular mechanisms underlying IGF-I-induced attenuation of the growth-inhibitory activity of trastuzumab (Herceptin) on SKBR3 breast cancer cells
    • LU Y, ZI X, POLLAK M: Molecular mechanisms underlying IGF-I-induced attenuation of the growth-inhibitory activity of trastuzumab (Herceptin) on SKBR3 breast cancer cells. Int. J. Cancer (2004) 108(3):334-341.
    • (2004) Int. J. Cancer , vol.108 , Issue.3 , pp. 334-341
    • LU, Y.1    ZI, X.2    POLLAK, M.3
  • 60
    • 28244432561 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells
    • NAHTA R, YUAN LX, ZHANG B, KOBAYASHI R, ESTEVA FJ: Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells. Cancer Res. (2005) 65(23):11118-11128.
    • (2005) Cancer Res , vol.65 , Issue.23 , pp. 11118-11128
    • NAHTA, R.1    YUAN, L.X.2    ZHANG, B.3    KOBAYASHI, R.4    ESTEVA, F.J.5
  • 61
    • 5044221199 scopus 로고    scopus 로고
    • The efficacy of herceptin therapies is influenced by the expression of other erbB receptors, their ligands and the activation of downstream signalling proteins
    • SMITH BL, CHIN D, MALTZMAN W, CROSBY K, HORTOBAGYI GN, BACUS SS: The efficacy of herceptin therapies is influenced by the expression of other erbB receptors, their ligands and the activation of downstream signalling proteins. Br. J. Cancer (2004) 91(6):1190-1194.
    • (2004) Br. J. Cancer , vol.91 , Issue.6 , pp. 1190-1194
    • SMITH, B.L.1    CHIN, D.2    MALTZMAN, W.3    CROSBY, K.4    HORTOBAGYI, G.N.5    BACUS, S.S.6
  • 62
    • 33646746413 scopus 로고    scopus 로고
    • A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer
    • XIA W, BACUS S, HEGDE P et al.: A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer. Proc. Natl. Acad. Sci. USA (2006) 103(20):7795-7800.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , Issue.20 , pp. 7795-7800
    • XIA, W.1    BACUS, S.2    HEGDE, P.3
  • 63
    • 33745615848 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor 1 (IGFR-1) is significantly associated with longer survival in non-small-cell lung cancer patients treated with gefitinib
    • CAPPUZZO F, TOSCHI I, TALLINI G et al.: Insulin-like growth factor receptor 1 (IGFR-1) is significantly associated with longer survival in non-small-cell lung cancer patients treated with gefitinib. Ann. Oncol. (2006) 17(7):1120-1127.
    • (2006) Ann. Oncol , vol.17 , Issue.7 , pp. 1120-1127
    • CAPPUZZO, F.1    TOSCHI, I.2    TALLINI, G.3
  • 64
    • 34249049000 scopus 로고    scopus 로고
    • Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib
    • MORGILLO F, KIM WY, KIM ES, CIARDIELLO F, HONG WK, LEE HY: Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib. Clin. Cancer Res. (2007) 13(9):2795-2803.
    • (2007) Clin. Cancer Res , vol.13 , Issue.9 , pp. 2795-2803
    • MORGILLO, F.1    KIM, W.Y.2    KIM, E.S.3    CIARDIELLO, F.4    HONG, W.K.5    LEE, H.Y.6
  • 65
    • 19944427176 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells
    • JONES HE, GODDARD L, GEE JM et al.: Insulin-like growth factor-I receptor signalling and acquired resistance to gefitinib (ZD1839; Iressa) in human breast and prostate cancer cells. Endocr. Relat. Cancer (2004) 11(4):793-814.
    • (2004) Endocr. Relat. Cancer , vol.11 , Issue.4 , pp. 793-814
    • JONES, H.E.1    GODDARD, L.2    GEE, J.M.3
  • 66
    • 3142676436 scopus 로고    scopus 로고
    • Overriding imatinib resistance with a novel ABL kinase inhibitor
    • SHAH NP, TRAN C, LEE FY, CHEN P, NORRIS D, SAWYERS CL: Overriding imatinib resistance with a novel ABL kinase inhibitor. Science (2004) 305(5682):399-401.
    • (2004) Science , vol.305 , Issue.5682 , pp. 399-401
    • SHAH, N.P.1    TRAN, C.2    LEE, F.Y.3    CHEN, P.4    NORRIS, D.5    SAWYERS, C.L.6
  • 68
    • 33746326785 scopus 로고    scopus 로고
    • The role of the bone microenvironment in the pathophysiology and therapeutic management of multiple myeloma: Interplay of growth factors, their receptors and stromal interactions
    • MITSIADES CS, MITSIADES NS, MUNSHI NC, RICHARDSON PG, ANDERSON KC: The role of the bone microenvironment in the pathophysiology and therapeutic management of multiple myeloma: interplay of growth factors, their receptors and stromal interactions. Eur. J. Cancer (2006) 42(11):1564-1573.
    • (2006) Eur. J. Cancer , vol.42 , Issue.11 , pp. 1564-1573
    • MITSIADES, C.S.1    MITSIADES, N.S.2    MUNSHI, N.C.3    RICHARDSON, P.G.4    ANDERSON, K.C.5
  • 69
    • 34047136169 scopus 로고    scopus 로고
    • The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis
    • CARRASCO DR, SUKHDEO K, PROTOPOPOVA M et al.: The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis. Cancer Cell (2007) 11(4):349-360.
    • (2007) Cancer Cell , vol.11 , Issue.4 , pp. 349-360
    • CARRASCO, D.R.1    SUKHDEO, K.2    PROTOPOPOVA, M.3
  • 70
    • 3242777803 scopus 로고    scopus 로고
    • Advances in biology of multiple myeloma: Clinical applications
    • HIDESHIMA T, BERGSAGEL PL, KUEHL WM, ANDERSON KC: Advances in biology of multiple myeloma: clinical applications. Blood (2004) 104(3):607-618.
    • (2004) Blood , vol.104 , Issue.3 , pp. 607-618
    • HIDESHIMA, T.1    BERGSAGEL, P.L.2    KUEHL, W.M.3    ANDERSON, K.C.4
  • 71
    • 34147129816 scopus 로고    scopus 로고
    • Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
    • MULLIGAN G, MITSIADES C, BRYANT B et al.: Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib. Blood (2007) 109(8):3177-3188.
    • (2007) Blood , vol.109 , Issue.8 , pp. 3177-3188
    • MULLIGAN, G.1    MITSIADES, C.2    BRYANT, B.3
  • 72
    • 33750209537 scopus 로고    scopus 로고
    • A novel proteasome inhibitor NPI-0052 as an anticancer therapy
    • CHAUHAN D, HIDESHIMA T, ANDERSON KC: A novel proteasome inhibitor NPI-0052 as an anticancer therapy. Br. J. Cancer (2006) 95(8):961-965.
    • (2006) Br. J. Cancer , vol.95 , Issue.8 , pp. 961-965
    • CHAUHAN, D.1    HIDESHIMA, T.2    ANDERSON, K.C.3
  • 73
    • 33947280591 scopus 로고    scopus 로고
    • Targeted therapy of multiple myeloma based upon tumor-microenvironmental interactions
    • ANDERSON KC: Targeted therapy of multiple myeloma based upon tumor-microenvironmental interactions. Exp. Hematol. (2007) 35(4 Suppl. 1): 155-162.
    • (2007) Exp. Hematol , vol.35 , Issue.4 SUPPL. 1 , pp. 155-162
    • ANDERSON, K.C.1
  • 74
    • 2942512316 scopus 로고    scopus 로고
    • Highly altered protein expression profile in the adriamycin resistant MCF-7 cell line
    • GEHRMANN MI, FENSELAU C, HATHOUT Y: Highly altered protein expression profile in the adriamycin resistant MCF-7 cell line. J. Proteome Res. (2004) 3(3):403-409.
    • (2004) J. Proteome Res , vol.3 , Issue.3 , pp. 403-409
    • GEHRMANN, M.I.1    FENSELAU, C.2    HATHOUT, Y.3
  • 75
    • 17144430514 scopus 로고    scopus 로고
    • Down-regulation of mitochondrial F1F0-ATP synthase in human colon cancer cells with induced 5-fluorouracil resistance
    • SHIN YK, YOO BC, CHANG HJ et al.: Down-regulation of mitochondrial F1F0-ATP synthase in human colon cancer cells with induced 5-fluorouracil resistance. Cancer Res. (2005) 65(8):3162-3170.
    • (2005) Cancer Res , vol.65 , Issue.8 , pp. 3162-3170
    • SHIN, Y.K.1    YOO, B.C.2    CHANG, H.J.3
  • 76
    • 32944478288 scopus 로고    scopus 로고
    • Proteomics of xenografted human breast cancer indicates novel targets related to tamoxifen resistance
    • BESADA V, DIAZ M, BECKER M, RAMOS Y, CASTELLANOS-SERRA L, FICHTNER I: Proteomics of xenografted human breast cancer indicates novel targets related to tamoxifen resistance. Proteomics (2006) 6(3):1038-1048.
    • (2006) Proteomics , vol.6 , Issue.3 , pp. 1038-1048
    • BESADA, V.1    DIAZ, M.2    BECKER, M.3    RAMOS, Y.4    CASTELLANOS-SERRA, L.5    FICHTNER, I.6
  • 77
    • 33645066349 scopus 로고    scopus 로고
    • Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukaemia - an in vivo study
    • VERRILLS NM, LIEM NI, LIAW TY, HOOD BD, LOCK RB, KAVALLARIS M: Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukaemia - an in vivo study. Proteomics (2006) 6(5):1681-1694.
    • (2006) Proteomics , vol.6 , Issue.5 , pp. 1681-1694
    • VERRILLS, N.M.1    LIEM, N.I.2    LIAW, T.Y.3    HOOD, B.D.4    LOCK, R.B.5    KAVALLARIS, M.6
  • 78
    • 33646137799 scopus 로고    scopus 로고
    • Unsupervised proteome analysis of human leukaemia cells identifies the valosin-containing protein as a putative marker for glucocorticoid resistance
    • LAUTEN M, SCHRAUDER A, KARDINAL C et al.: Unsupervised proteome analysis of human leukaemia cells identifies the valosin-containing protein as a putative marker for glucocorticoid resistance. Leukemia (2006) 20(5):820-826.
    • (2006) Leukemia , vol.20 , Issue.5 , pp. 820-826
    • LAUTEN, M.1    SCHRAUDER, A.2    KARDINAL, C.3
  • 79
    • 27744607603 scopus 로고    scopus 로고
    • Identification of reproducible low mass SELDI protein profiles specific to cisplatin resistance in human ovarian cancer cells
    • BRITTEN RA, HARDY C, VLAHOU A, GREGORY B, GIRI PS, DRAKE R: Identification of reproducible low mass SELDI protein profiles specific to cisplatin resistance in human ovarian cancer cells. Oncol. Rep. (2005) 14(5):1323-1330.
    • (2005) Oncol. Rep , vol.14 , Issue.5 , pp. 1323-1330
    • BRITTEN, R.A.1    HARDY, C.2    VLAHOU, A.3    GREGORY, B.4    GIRI, P.S.5    DRAKE, R.6
  • 80
    • 33645463240 scopus 로고    scopus 로고
    • Proteins associated with cisplatin resistance in ovarian cancer cells identified by quantitative proteomic technology and integrated with mRNA expression levels
    • STEWART JJ, WHITE JT, YAN X et al.: Proteins associated with cisplatin resistance in ovarian cancer cells identified by quantitative proteomic technology and integrated with mRNA expression levels. Mol. Cell Proteomics (2006) 5(3):433-443.
    • (2006) Mol. Cell Proteomics , vol.5 , Issue.3 , pp. 433-443
    • STEWART, J.J.1    WHITE, J.T.2    YAN, X.3
  • 82
    • 33645851037 scopus 로고    scopus 로고
    • Ribozyme: A clinical tool
    • KHAN AU: Ribozyme: a clinical tool. Clin. Chim. Acta (2006) 367(1-2):20-27.
    • (2006) Clin. Chim. Acta , vol.367 , Issue.1-2 , pp. 20-27
    • KHAN, A.U.1
  • 84
    • 0034088857 scopus 로고    scopus 로고
    • A gene expression database for the molecular pharmacology of cancer
    • SCHERF U, ROSS DT, WALTHAM M et al.: A gene expression database for the molecular pharmacology of cancer. Nat. Genet. (2000) 24(3):236-244.
    • (2000) Nat. Genet , vol.24 , Issue.3 , pp. 236-244
    • SCHERF, U.1    ROSS, D.T.2    WALTHAM, M.3
  • 85
    • 0035845531 scopus 로고    scopus 로고
    • Chemosensitivity prediction by transcriptional profiling
    • STAUNTON JE, SLONIM DK, COLLER HA et al.: Chemosensitivity prediction by transcriptional profiling. Proc. Natl. Acad. Sci. USA (2001) 98(19):10787-10792.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.19 , pp. 10787-10792
    • STAUNTON, J.E.1    SLONIM, D.K.2    COLLER, H.A.3
  • 86
    • 0033891762 scopus 로고    scopus 로고
    • Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray
    • KUDOH K, RAMANNA M, RAVATN R et al.: Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray. Cancer Res. (2000) 60(15):4161-4166.
    • (2000) Cancer Res , vol.60 , Issue.15 , pp. 4161-4166
    • KUDOH, K.1    RAMANNA, M.2    RAVATN, R.3
  • 87
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • SORLIE T, PEROU CM, TIBSHIRANI R et al.: Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl. Acad. Sci. USA (2001) 98(19):10869-10874.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.19 , pp. 10869-10874
    • SORLIE, T.1    PEROU, C.M.2    TIBSHIRANI, R.3
  • 89
    • 3042655539 scopus 로고    scopus 로고
    • Cell-type-specific responses to chemotherapeutics in breast cancer
    • TROESTER MA, HOADLEY KA, SORLIE T et al.: Cell-type-specific responses to chemotherapeutics in breast cancer. Cancer Res. (2004) 64(12):4218-4226.
    • (2004) Cancer Res , vol.64 , Issue.12 , pp. 4218-4226
    • TROESTER, M.A.1    HOADLEY, K.A.2    SORLIE, T.3
  • 90
    • 1242340503 scopus 로고    scopus 로고
    • A novel time-course cDNA microarray analysis method identifies genes associated with the development of cisplatin resistance
    • WHITESIDE MA, CHEN DT, DESMOND RA, ABDULKADIR SA, JOHANNING GL: A novel time-course cDNA microarray analysis method identifies genes associated with the development of cisplatin resistance. Oncogene (2004) 23(3):744-752.
    • (2004) Oncogene , vol.23 , Issue.3 , pp. 744-752
    • WHITESIDE, M.A.1    CHEN, D.T.2    DESMOND, R.A.3    ABDULKADIR, S.A.4    JOHANNING, G.L.5
  • 91
    • 4344564478 scopus 로고    scopus 로고
    • Identification of novel genes associated with the response to 5-FU treatment in gastric cancer cell lines using a cDNA microarray
    • PARK JS, YOUNG YOON S, KIM JM, YEOM YI, KIM YS, KIM NS: Identification of novel genes associated with the response to 5-FU treatment in gastric cancer cell lines using a cDNA microarray. Cancer Lett. (2004) 214(1):19-33.
    • (2004) Cancer Lett , vol.214 , Issue.1 , pp. 19-33
    • PARK, J.S.1    YOUNG, Y.S.2    KIM, J.M.3    YEOM, Y.I.4    KIM, Y.S.5    KIM, N.S.6
  • 92
    • 33746437215 scopus 로고    scopus 로고
    • Transcriptional profiling of MCF7 breast cancer cells in response to 5-fluorouracil: Relationship with cell cycle changes and apoptosis, and identification of novel targets of p53
    • HERNANDEZ-VARGAS H, BALLESTAR E, CARMONA-SAEZ P et al.: Transcriptional profiling of MCF7 breast cancer cells in response to 5-fluorouracil: relationship with cell cycle changes and apoptosis, and identification of novel targets of p53. Int. J. Cancer (2006) 119(5):1164-1175.
    • (2006) Int. J. Cancer , vol.119 , Issue.5 , pp. 1164-1175
    • HERNANDEZ-VARGAS, H.1    BALLESTAR, E.2    CARMONA-SAEZ, P.3
  • 93
    • 23844481928 scopus 로고    scopus 로고
    • Establishment and gene analysis of a cisplatin-resistant cell lineSa-3R, derived from oral squamous cell carcinoma
    • NAKATANI K, NAKAMURA M, UZAWA K et al.: Establishment and gene analysis of a cisplatin-resistant cell lineSa-3R, derived from oral squamous cell carcinoma. Oncol. Rep. (2005) 13(4):709-714.
    • (2005) Oncol. Rep , vol.13 , Issue.4 , pp. 709-714
    • NAKATANI, K.1    NAKAMURA, M.2    UZAWA, K.3
  • 94
    • 33744971886 scopus 로고    scopus 로고
    • Gene expression profiles with cDNA microarray reveal RhoGDI as a predictive marker for paclitaxel resistance in ovarian cancers
    • GOTO T, TAKANO M, SAKAMOTO M et al.: Gene expression profiles with cDNA microarray reveal RhoGDI as a predictive marker for paclitaxel resistance in ovarian cancers. Oncol. Rep. (2006) 15(5):1265-1271.
    • (2006) Oncol. Rep , vol.15 , Issue.5 , pp. 1265-1271
    • GOTO, T.1    TAKANO, M.2    SAKAMOTO, M.3
  • 95
    • 24944521677 scopus 로고    scopus 로고
    • Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles
    • RICKARDSON L, FRYKNAS M, DHAR S et al.: Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles. Br. J. Cancer (2005) 93(4):483-492.
    • (2005) Br. J. Cancer , vol.93 , Issue.4 , pp. 483-492
    • RICKARDSON, L.1    FRYKNAS, M.2    DHAR, S.3
  • 96
    • 10844235689 scopus 로고    scopus 로고
    • Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes
    • GILLET JP, EFFERTH T, STEINBACH D et al.: Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes. Cancer Res. (2004) 64(24):8987-8993.
    • (2004) Cancer Res , vol.64 , Issue.24 , pp. 8987-8993
    • GILLET, J.P.1    EFFERTH, T.2    STEINBACH, D.3
  • 97
    • 0035420014 scopus 로고    scopus 로고
    • Prediction of sensitivity of esophageal tumors to adjuvant chemotherapy by cDNA microarray analysis of gene-expression profiles
    • KIHARA C, TSUNODA T, TANAKA T et al.: Prediction of sensitivity of esophageal tumors to adjuvant chemotherapy by cDNA microarray analysis of gene-expression profiles. Cancer Res. (2001) 61(17):6474-6479.
    • (2001) Cancer Res , vol.61 , Issue.17 , pp. 6474-6479
    • KIHARA, C.1    TSUNODA, T.2    TANAKA, T.3
  • 98
    • 0037142053 scopus 로고    scopus 로고
    • The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
    • ROSENWALD A, WRIGHT G, CHAN WC et al.: The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N. Engl. J. Med. (2002) 346(25):1937-1947.
    • (2002) N. Engl. J. Med , vol.346 , Issue.25 , pp. 1937-1947
    • ROSENWALD, A.1    WRIGHT, G.2    CHAN, W.C.3
  • 99
    • 33644762282 scopus 로고    scopus 로고
    • The impact of expression profiling on prognostic and predictive testing in breast cancer
    • REIS-FILHO JS, WESTBURY C, PIERGA JY: The impact of expression profiling on prognostic and predictive testing in breast cancer. J. Clin. Pathol. (2006) 59(3):225-231.
    • (2006) J. Clin. Pathol , vol.59 , Issue.3 , pp. 225-231
    • REIS-FILHO, J.S.1    WESTBURY, C.2    PIERGA, J.Y.3
  • 100
    • 0036836249 scopus 로고    scopus 로고
    • Global gene expression changes during neoadjuvant chemotherapy for human breast cancer
    • BUCHHOLZ TA, STIVERS DN, STEC J et al.: Global gene expression changes during neoadjuvant chemotherapy for human breast cancer. Cancer J. (2002) 8(6):461-468.
    • (2002) Cancer J , vol.8 , Issue.6 , pp. 461-468
    • BUCHHOLZ, T.A.1    STIVERS, D.N.2    STEC, J.3
  • 101
    • 13844311931 scopus 로고    scopus 로고
    • Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer
    • SOTIRIOU C, POWLES TJ, DOWSETT M et al.: Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer. Breast Cancer Res. (2002) 4(3): R3.
    • (2002) Breast Cancer Res , vol.4 , Issue.3
    • SOTIRIOU, C.1    POWLES, T.J.2    DOWSETT, M.3
  • 102
    • 0042125511 scopus 로고    scopus 로고
    • Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer
    • CHANG JC, WOOTEN EC, TSIMELZON A et al.: Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer. Lancet (2003) 362(9381):362-369.
    • (2003) Lancet , vol.362 , Issue.9381 , pp. 362-369
    • CHANG, J.C.1    WOOTEN, E.C.2    TSIMELZON, A.3
  • 103
    • 2942729848 scopus 로고    scopus 로고
    • Gene expression profiles predict complete pathologic response to neoadjuvant paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide chemotherapy in breast cancer
    • AYERS M, SYMMANS WF, STEC J et al.: Gene expression profiles predict complete pathologic response to neoadjuvant paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide chemotherapy in breast cancer. J. Clin. Oncol. (2004) 22(12):2284-2293.
    • (2004) J. Clin. Oncol , vol.22 , Issue.12 , pp. 2284-2293
    • AYERS, M.1    SYMMANS, W.F.2    STEC, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.