Glucose metabolites inhibit protein phosphatases and directly promote insulin exocytosis in pancreatic β-cells

Endocrinology

Volumn 143, Issue 12, 2002, Pages 4592-4598

  Sjöholm, Åke ^a   Lehtihet, Mikael ^a   Efanov, Alexandre M ^b   Zaitsev, Sergei V ^b,c   Berggren, Per Olof ^b   Honkanen, Richard E ^d  

^a STOCKHOLM SÖDER HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c MOSCOW STATE UNIVERSITY   (Russian Federation)

^d UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CITRIC ACID; FRUCTOSE BISPHOSPHATASE; GLUCOSE; GLYCEROPHOSPHATE; GUANOSINE TRIPHOSPHATE; INSULIN; OKADAIC ACID; OXALOACETIC ACID; PHOSPHOENOLPYRUVATE; PHOSPHOPROTEIN PHOSPHATASE; SERINE; THREONINE;

ANIMAL CELL; ARTICLE; CALCIUM BLOOD LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; CITRIC ACID CYCLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; EXOCYTOSIS; GLUCOSE METABOLISM; GLYCOLYSIS; HORMONE TRANSPORT; HUMAN; INSULIN RELEASE; METABOLITE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM;

ANIMALS; CALCIUM; CITRIC ACID; DRUG SYNERGISM; ENZYME INHIBITORS; EXOCYTOSIS; FRUCTOSEDIPHOSPHATES; GLUCOSE; GLYCERIC ACIDS; GUANOSINE TRIPHOSPHATE; INSULIN; INSULINOMA; ISLETS OF LANGERHANS; OKADAIC ACID; OXALOACETATE; PANCREATIC NEOPLASMS; PHOSPHOENOLPYRUVATE; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; RATS; TUMOR CELLS, CULTURED;

EID: 0036892130     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-220672     Document Type: Article

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