Sepsis-induced cardiac mitochondrial dysfunction involves altered mitochondrial-localization of tyrosine kinase Src and tyrosine phosphatase SHP2

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Zang, Qun S ^a   Martinez, Bobbie ^a   Yao, Xiao ^a   Maass, David L ^a   Ma, Lisha ^a   Wolf, Steven E ^a   Minei, Joseph P ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACONITATE HYDRATASE; CYCLOPHILIN D; CYTOCHROME C; MITOCHONDRIAL ENZYME; MITOCHONDRIAL PROTEIN; PORIN; PROTEIN NDUFB8; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); STRUCTURAL PROTEIN; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE COMPLEX SUBUNIT B; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE COMPLEX; HEART DISEASE; HEART MITOCHONDRION; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING; MALE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SEPSIS; STREPTOCOCCUS PNEUMONIA; WESTERN BLOTTING;

ANIMALS; CYCLOPHILINS; CYTOCHROMES C; ENDOPEPTIDASE K; MALE; MITOCHONDRIA; MYOCARDIUM; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PORINS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SEPSIS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STREPTOCOCCUS PNEUMONIAE; SUBCELLULAR FRACTIONS;

RATTUS; STREPTOCOCCUS PNEUMONIAE;

EID: 84865611273     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043424     Document Type: Article

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