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Volumn 53, Issue 4, 2012, Pages 521-531

Dilated cardiomyopathy and mitochondrial dysfunction in Sirt1-deficient mice: A role for Sirt1-Mef2 in adult heart

Author keywords

Dilated cardiomyopathy; Mef2; Mitochondrial dysfunction; Sirt1

Indexed keywords

MYOCYTE ENHANCER FACTOR 2; SIRTUIN 1;

EID: 84865555215     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2012.07.019     Document Type: Article
Times cited : (75)

References (37)
  • 1
    • 77249109399 scopus 로고    scopus 로고
    • Dilated cardiomyopathy
    • Jefferies J.L., Towbin J.A. Dilated cardiomyopathy. Lancet 2010, 375:752-762.
    • (2010) Lancet , vol.375 , pp. 752-762
    • Jefferies, J.L.1    Towbin, J.A.2
  • 2
    • 36549023058 scopus 로고    scopus 로고
    • Alterations in energy metabolism in cardiomyopathies
    • Taha M., Lopaschuk G.D. Alterations in energy metabolism in cardiomyopathies. Ann Med 2007, 39:594-607.
    • (2007) Ann Med , vol.39 , pp. 594-607
    • Taha, M.1    Lopaschuk, G.D.2
  • 3
    • 0036774412 scopus 로고    scopus 로고
    • Understanding the impact of mitochondrial defects in cardiovascular disease: a review
    • Marin-Garcia J., Goldenthal M.J. Understanding the impact of mitochondrial defects in cardiovascular disease: a review. J Card Fail 2002, 8:347-361.
    • (2002) J Card Fail , vol.8 , pp. 347-361
    • Marin-Garcia, J.1    Goldenthal, M.J.2
  • 4
    • 0141814680 scopus 로고    scopus 로고
    • Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
    • Cheng H.L., Mostoslavsky R., Saito S., Manis J.P., Gu Y., Patel P., et al. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A 2003, 100:10794-10799.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10794-10799
    • Cheng, H.L.1    Mostoslavsky, R.2    Saito, S.3    Manis, J.P.4    Gu, Y.5    Patel, P.6
  • 6
    • 79955397959 scopus 로고    scopus 로고
    • Sirt1 acts in association with PPAR{alpha} to protect the heart from hypertrophy, metabolic dysregulation, and inflammation
    • Planavila A., Iglesias R., Giralt M., Villarroya F. Sirt1 acts in association with PPAR{alpha} to protect the heart from hypertrophy, metabolic dysregulation, and inflammation. Cardiovasc Res 2011, 90:276-284.
    • (2011) Cardiovasc Res , vol.90 , pp. 276-284
    • Planavila, A.1    Iglesias, R.2    Giralt, M.3    Villarroya, F.4
  • 7
    • 0028347574 scopus 로고
    • Inherited cardiomyopathies
    • Kelly D.P., Strauss A.W. Inherited cardiomyopathies. N Engl J Med 1994, 330:913-919.
    • (1994) N Engl J Med , vol.330 , pp. 913-919
    • Kelly, D.P.1    Strauss, A.W.2
  • 8
    • 0033525773 scopus 로고    scopus 로고
    • Mitochondrial diseases in man and mouse
    • Wallace D.C. Mitochondrial diseases in man and mouse. Science 1999, 283:1482-1488.
    • (1999) Science , vol.283 , pp. 1482-1488
    • Wallace, D.C.1
  • 9
    • 5444228319 scopus 로고    scopus 로고
    • Regulation of mitochondrial proliferation in the heart: power-plant failure contributes to cardiac failure in hypertrophy
    • Goffart S., von Kleist-Retzow J.C., Wiesner R.J. Regulation of mitochondrial proliferation in the heart: power-plant failure contributes to cardiac failure in hypertrophy. Cardiovasc Res 2004, 64:198-207.
    • (2004) Cardiovasc Res , vol.64 , pp. 198-207
    • Goffart, S.1    von Kleist-Retzow, J.C.2    Wiesner, R.J.3
  • 10
    • 0036851837 scopus 로고    scopus 로고
    • Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor
    • Naya F.J., Black B.L., Wu H., Bassel-Duby R., Richardson J.A., Hill J.A., et al. Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nat Med 2002, 8:1303-1309.
    • (2002) Nat Med , vol.8 , pp. 1303-1309
    • Naya, F.J.1    Black, B.L.2    Wu, H.3    Bassel-Duby, R.4    Richardson, J.A.5    Hill, J.A.6
  • 11
    • 20444466460 scopus 로고    scopus 로고
    • Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy
    • Planavila A., Laguna J.C., Vazquez-Carrera M. Nuclear factor-kappaB activation leads to down-regulation of fatty acid oxidation during cardiac hypertrophy. J Biol Chem 2005, 280:17464-17471.
    • (2005) J Biol Chem , vol.280 , pp. 17464-17471
    • Planavila, A.1    Laguna, J.C.2    Vazquez-Carrera, M.3
  • 12
    • 0030760230 scopus 로고    scopus 로고
    • Saturated but not mono-unsaturated fatty acids induce apoptotic cell death in neonatal rat ventricular myocytes
    • de Vries J.E., Vork M.M., Roemen T.H., de Jong Y.F., Cleutjens J.P., van der Vusse G.J., et al. Saturated but not mono-unsaturated fatty acids induce apoptotic cell death in neonatal rat ventricular myocytes. J Lipid Res 1997, 38:1384-1394.
    • (1997) J Lipid Res , vol.38 , pp. 1384-1394
    • de Vries, J.E.1    Vork, M.M.2    Roemen, T.H.3    de Jong, Y.F.4    Cleutjens, J.P.5    van der Vusse, G.J.6
  • 13
    • 69249116960 scopus 로고    scopus 로고
    • SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD
    • Amat R., Planavila A., Chen S.L., Iglesias R., Giralt M., Villarroya F. SIRT1 controls the transcription of the peroxisome proliferator-activated receptor-gamma Co-activator-1alpha (PGC-1alpha) gene in skeletal muscle through the PGC-1alpha autoregulatory loop and interaction with MyoD. J Biol Chem 2009, 284:21872-21880.
    • (2009) J Biol Chem , vol.284 , pp. 21872-21880
    • Amat, R.1    Planavila, A.2    Chen, S.L.3    Iglesias, R.4    Giralt, M.5    Villarroya, F.6
  • 15
    • 33847075487 scopus 로고    scopus 로고
    • Decreased systolic function and inadequate hypertrophy in large and small breed dogs with chronic mitral valve insufficiency
    • Borgarelli M., Tarducci A., Zanatta R., Haggstrom J. Decreased systolic function and inadequate hypertrophy in large and small breed dogs with chronic mitral valve insufficiency. J Vet Intern Med 2007, 21:61-67.
    • (2007) J Vet Intern Med , vol.21 , pp. 61-67
    • Borgarelli, M.1    Tarducci, A.2    Zanatta, R.3    Haggstrom, J.4
  • 16
    • 0025286817 scopus 로고
    • Elevated circulating levels of tumor necrosis factor in severe chronic heart failure
    • Levine B., Kalman J., Mayer L., Fillit H.M., Packer M. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 1990, 323:236-241.
    • (1990) N Engl J Med , vol.323 , pp. 236-241
    • Levine, B.1    Kalman, J.2    Mayer, L.3    Fillit, H.M.4    Packer, M.5
  • 17
    • 0028982834 scopus 로고
    • Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes
    • Thaik C.M., Calderone A., Takahashi N., Colucci W.S. Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes. J Clin Invest 1995, 96:1093-1099.
    • (1995) J Clin Invest , vol.96 , pp. 1093-1099
    • Thaik, C.M.1    Calderone, A.2    Takahashi, N.3    Colucci, W.S.4
  • 18
    • 1542297737 scopus 로고    scopus 로고
    • A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts
    • Hansson A., Hance N., Dufour E., Rantanen A., Hultenby K., Clayton D.A., et al. A switch in metabolism precedes increased mitochondrial biogenesis in respiratory chain-deficient mouse hearts. Proc Natl Acad Sci U S A 2004, 101:3136-3141.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3136-3141
    • Hansson, A.1    Hance, N.2    Dufour, E.3    Rantanen, A.4    Hultenby, K.5    Clayton, D.A.6
  • 19
    • 26244465857 scopus 로고    scopus 로고
    • Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca2+dependent pathway and a reduced mitochondrial protein import
    • Mercy L., Pauw A., Payen L., Tejerina S., Houbion A., Demazy C., et al. Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca2+dependent pathway and a reduced mitochondrial protein import. FEBS J 2005, 272:5031-5055.
    • (2005) FEBS J , vol.272 , pp. 5031-5055
    • Mercy, L.1    Pauw, A.2    Payen, L.3    Tejerina, S.4    Houbion, A.5    Demazy, C.6
  • 20
    • 45549087482 scopus 로고    scopus 로고
    • Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits
    • Ramachandran B., Yu G., Gulick T. Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits. J Biol Chem 2008, 283:11935-11946.
    • (2008) J Biol Chem , vol.283 , pp. 11935-11946
    • Ramachandran, B.1    Yu, G.2    Gulick, T.3
  • 21
    • 38049147787 scopus 로고    scopus 로고
    • MEF2: a central regulator of diverse developmental programs
    • Potthoff M.J., Olson E.N. MEF2: a central regulator of diverse developmental programs. Development 2007, 134:4131-4140.
    • (2007) Development , vol.134 , pp. 4131-4140
    • Potthoff, M.J.1    Olson, E.N.2
  • 22
    • 17644389201 scopus 로고    scopus 로고
    • Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation
    • Ma K., Chan J.K., Zhu G., Wu Z. Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation. Mol Cell Biol 2005, 25:3575-3582.
    • (2005) Mol Cell Biol , vol.25 , pp. 3575-3582
    • Ma, K.1    Chan, J.K.2    Zhu, G.3    Wu, Z.4
  • 23
    • 33646942503 scopus 로고    scopus 로고
    • Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice
    • Xu J., Gong N.L., Bodi I., Aronow B.J., Backx P.H., Molkentin J.D. Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice. J Biol Chem 2006, 281:9152-9162.
    • (2006) J Biol Chem , vol.281 , pp. 9152-9162
    • Xu, J.1    Gong, N.L.2    Bodi, I.3    Aronow, B.J.4    Backx, P.H.5    Molkentin, J.D.6
  • 24
    • 15444377466 scopus 로고    scopus 로고
    • SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1
    • Bouras T., Fu M., Sauve A.A., Wang F., Quong A.A., Perkins N.D., et al. SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. J Biol Chem 2005, 280:10264-10276.
    • (2005) J Biol Chem , vol.280 , pp. 10264-10276
    • Bouras, T.1    Fu, M.2    Sauve, A.A.3    Wang, F.4    Quong, A.A.5    Perkins, N.D.6
  • 25
    • 34249669270 scopus 로고    scopus 로고
    • Sirt1 regulates aging and resistance to oxidative stress in the heart
    • Alcendor R.R., Gao S., Zhai P., Zablocki D., Holle E., Yu X., et al. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 2007, 100:1512-1521.
    • (2007) Circ Res , vol.100 , pp. 1512-1521
    • Alcendor, R.R.1    Gao, S.2    Zhai, P.3    Zablocki, D.4    Holle, E.5    Yu, X.6
  • 26
    • 79960620082 scopus 로고    scopus 로고
    • The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy
    • Sundaresan N.R., Pillai V.B., Wolfgeher D., Samant S., Vasudevan P., Parekh V., et al. The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy. Sci Signal 2011, 4:ra46.
    • (2011) Sci Signal , vol.4
    • Sundaresan, N.R.1    Pillai, V.B.2    Wolfgeher, D.3    Samant, S.4    Vasudevan, P.5    Parekh, V.6
  • 27
  • 28
    • 0038162526 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations and oxidative stress in mitochondrial diseases
    • Wei Y.H., Lee H.C. Mitochondrial DNA mutations and oxidative stress in mitochondrial diseases. Adv Clin Chem 2003, 37:83-128.
    • (2003) Adv Clin Chem , vol.37 , pp. 83-128
    • Wei, Y.H.1    Lee, H.C.2
  • 29
    • 0031011211 scopus 로고    scopus 로고
    • A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator
    • Graham B.H., Waymire K.G., Cottrell B., Trounce I.A., MacGregor G.R., Wallace D.C. A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator. Nat Genet 1997, 16:226-234.
    • (1997) Nat Genet , vol.16 , pp. 226-234
    • Graham, B.H.1    Waymire, K.G.2    Cottrell, B.3    Trounce, I.A.4    MacGregor, G.R.5    Wallace, D.C.6
  • 30
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
    • Rodgers J.T., Lerin C., Haas W., Gygi S.P., Spiegelman B.M., Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 2005, 434:113-118.
    • (2005) Nature , vol.434 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3    Gygi, S.P.4    Spiegelman, B.M.5    Puigserver, P.6
  • 31
    • 34247259630 scopus 로고    scopus 로고
    • Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha
    • Gerhart-Hines Z., Rodgers J.T., Bare O., Lerin C., Kim S.H., Mostoslavsky R., et al. Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha. EMBO J 2007, 26:1913-1923.
    • (2007) EMBO J , vol.26 , pp. 1913-1923
    • Gerhart-Hines, Z.1    Rodgers, J.T.2    Bare, O.3    Lerin, C.4    Kim, S.H.5    Mostoslavsky, R.6
  • 32
    • 24144463983 scopus 로고    scopus 로고
    • Metabolic control through the PGC-1 family of transcription coactivators
    • Lin J., Handschin C., Spiegelman B.M. Metabolic control through the PGC-1 family of transcription coactivators. Cell Metab 2005, 1:361-370.
    • (2005) Cell Metab , vol.1 , pp. 361-370
    • Lin, J.1    Handschin, C.2    Spiegelman, B.M.3
  • 33
    • 25444462980 scopus 로고    scopus 로고
    • Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications
    • Zhao X., Sternsdorf T., Bolger T.A., Evans R.M., Yao T.P. Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. Mol Cell Biol 2005, 25:8456-8464.
    • (2005) Mol Cell Biol , vol.25 , pp. 8456-8464
    • Zhao, X.1    Sternsdorf, T.2    Bolger, T.A.3    Evans, R.M.4    Yao, T.P.5
  • 34
    • 70350129460 scopus 로고    scopus 로고
    • P300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts
    • Nakagawa Y., Kuwahara K., Takemura G., Akao M., Kato M., Arai Y., et al. p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts. Circ Res 2009, 105:746-754.
    • (2009) Circ Res , vol.105 , pp. 746-754
    • Nakagawa, Y.1    Kuwahara, K.2    Takemura, G.3    Akao, M.4    Kato, M.5    Arai, Y.6
  • 35
    • 44649119816 scopus 로고    scopus 로고
    • Transcriptional targets of sirtuins in the coordination of mammalian physiology
    • Feige J.N., Auwerx J. Transcriptional targets of sirtuins in the coordination of mammalian physiology. Curr Opin Cell Biol 2008, 20:303-309.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 303-309
    • Feige, J.N.1    Auwerx, J.2
  • 36
    • 0037325402 scopus 로고    scopus 로고
    • P300/cAMP-response-element-binding-protein ('CREB')-binding protein (CBP) modulates co-operation between myocyte enhancer factor 2A (MEF2A) and thyroid hormone receptor-retinoid X receptor
    • De L.A., Severino A., De P.P., Cottone G., De L.L., De F.M., et al. p300/cAMP-response-element-binding-protein ('CREB')-binding protein (CBP) modulates co-operation between myocyte enhancer factor 2A (MEF2A) and thyroid hormone receptor-retinoid X receptor. Biochem J 2003, 369:477-484.
    • (2003) Biochem J , vol.369 , pp. 477-484
    • De, L.A.1    Severino, A.2    De, P.P.3    Cottone, G.4    De, L.L.5    De, F.M.6
  • 37
    • 78649451690 scopus 로고    scopus 로고
    • Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes
    • Sun H., Yang X., Zhu J., Lv T., Chen Y., Chen G., et al. Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes. Life Sci 2010, 87:707-714.
    • (2010) Life Sci , vol.87 , pp. 707-714
    • Sun, H.1    Yang, X.2    Zhu, J.3    Lv, T.4    Chen, Y.5    Chen, G.6


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