The role of the Wnt/β-catenin pathway in the effect of implant topography on MG63 differentiation

Biomaterials

Volumn 33, Issue 32, 2012, Pages 7993-8002

  Wang, Wei ^a   Zhao, Lingzhou ^a   Ma, Qianli ^a   Wang, Qintao ^a   Chu, Paul K ^b   Zhang, Yumei ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b CITY UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Differentiation; MG63; Micro nano textured topography; Wnt; catenin

Indexed keywords

CYTOLOGY; DIFFERENTIATION (CALCULUS); GENE EXPRESSION; OSTEOBLASTS; PHOSPHATASES; SIGNALING; SURFACE TOPOGRAPHY; TOPOGRAPHY;

ALKALINE PHOSPHATASE; CELL DIFFERENTIATION; LOW DENSITY LIPOPROTEIN RECEPTORS; MG63; OSTEOBLAST DIFFERENTIATION; OSTEOGENESIS-RELATED GENES; PATHWAY INHIBITORS; SIGNALING CASCADES;

CELL SIGNALING;

ALKALINE PHOSPHATASE; BETA CATENIN; COLLAGEN; DICKKOPF 1 PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 2; WNT PROTEIN; WNT3A PROTEIN;

ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMPLANT; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TOPOGRAPHY;

EID: 84865551905     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.07.064     Document Type: Article

References (41)

1. 3 is mediated via protein kinase C- and protein kinase A-dependent pathways. Biomaterials 2001, 22:731-741.
2. Olivares-Navarrete R., Hyzy S.L., Park J.H., Dunn G.R., Haithcock D.A., Wasilewski C.E., et al. Mediation of osteogenic differentiation of human mesenchymal stem cells on titanium surfaces by a Wnt-integrin feedback loop. Biomaterials 2011, 32:6399-6411.
3. 3. Biomaterials 2006, 27:3716-3725.
4. Mendonca G., Mendonca D.B., Aragao F.J., Cooper L.F. Advancing dental implant surface technology-from micron- to nanotopography. Biomaterials 2008, 29:3822-3835.
5. Zhao L., Liu L., Wu Z., Zhang Y., Chu P.K. Effects of micropitted/nanotubular titania topographies on bone mesenchymal stem cell osteogenic differentiation. Biomaterials 2012, 33:2629-2641.
6. Zhao L., Mei S., Chu P.K., Zhang Y., Wu Z. The influence of hierarchical hybrid micro/nano-textured titanium surface with titania nanotubes on osteoblast functions. Biomaterials 2010, 31:5072-5082.
7. Gaur T., Lengner C.J., Hovhannisyan H., Bhat R.A., Bodine P.V., Komm B.S., et al. Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression. J Biol Chem 2005, 280:33132-33140.
8. Liu F., Kohlmeier S., Wang C.Y. Wnt signaling and skeletal development. Cell Signal 2008, 20:999-1009.
9. Tamura M., Nemoto E., Sato M.M., Nakashima A., Shimauchi H. Role of the Wnt signaling pathway in bone and tooth. Front Biosci (Elite Ed) 2010, 2:1405-1413.
10. Rawadi G., Vayssiere B., Dunn F., Baron R., Roman-Roman S. BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop. J Bone Miner Res 2003, 18:1842-1853.
11. Sunters A., Armstrong V.J., Zaman G., Kypta R.M., Kawano Y., Lanyon L.E., et al. Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-independent activation of beta-catenin signaling. J Biol Chem 2010, 285:8743-8758.
12. Galli C., Macaluso G.M., Piemontese M., Passeri G. Titanium topography controls FoxO/beta-catenin signaling. J Dent Res 2011, 90:360-364.
13. Galli C., Passeri G., Ravanetti F., Elezi E., Pedrazzoni M., Macaluso G.M. Rough surface topography enhances the activation of Wnt/β-catenin signaling in mesenchymal cells. J Biomed Mater Res A 2010, 95:682-690.
14. Vlacic-Zischke J., Hamlet S.M., Friis T., Tonetti M.S., Ivanovski S. The influence of surface microroughness and hydrophilicity of titanium on the up-regulation of TGFβ/BMP signalling in osteoblasts. Biomaterials 2011, 32:665-671.
15. 2 coating. J Mater Sci Technol 2012, 28:109-117.
16. Galli C., Piemontese M., Lumetti S., Ravanetti F., Macaluso G.M., Passeri G. Actin cytoskeleton controls activation of Wnt/β-catenin signaling in mesenchymal cells on implant surfaces with different topographies. Acta Biomater 2012, 8:2963-2968.
17. Schwartz Z., Olivares-Navarrete R., Wieland M., Cochran D.L., Boyan B.D. Mechanisms regulating increased production of osteoprotegerin by osteoblasts cultured on microstructured titanium surfaces. Biomaterials 2009, 30:3390-3396.
18. Miller J.R. The Wnts. Genome Biol 2002, 3. REVIEWS3001.
19. Li X., Liu P., Liu W., Maye P., Zhang J., Zhang Y., et al. Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation. Nat Genet 2005, 37:945-952.
20. van der Horst G., van der Werf S.M., Farih-Sips H., van Bezooijen R.L., Lowik C.W., Karperien M. Downregulation of Wnt signaling by increased expression of Dickkopf-1 and -2 is a prerequisite for late-stage osteoblast differentiation of KS483 cells. J Bone Miner Res 2005, 20:1867-1877.
21. Kawano Y., Kypta R. Secreted antagonists of the wnt signalling pathway. J Cell Sci 2003, 116:2627-2634.
22. Wennerberg A., Albrektsson T. Effects of titanium surface topography on bone integration: a systematic review. Clin Oral Implants Res 2009, 20:172-184.
23. Ducy P., Zhang R., Geoffroy V., Ridall A.L., Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 1997, 89:747-754.
24. Whyte M.P. Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization. Endocr Rev 1994, 15:439-461.
25. Hoffmann A., Gross G. BMP signaling pathways in cartilage and bone formation. Crit Rev Eukaryot Gene Expr 2001, 11:23-45.
26. Viguet-Carrin S., Garnero P., Delmas P.D. The role of collagen in bone strength. Osteoporos Int 2006, 17:319-336.
27. Bodine P.V., Komm B.S. Wnt signaling and osteoblastogenesis. Rev Endocr Metab Disord 2006, 7:33-39.
28. Olivares-Navarrete R., Hyzy S.L., Hutton D.L., Dunn G.R., Appert C., Boyan B.D., et al. Role of non-canonical Wnt signaling in osteoblast maturation on microstructured titanium surfaces. Acta Biomater 2011, 7:2740-2750.
29. Chakravorty N., Ivanovski S., Prasadam I., Crawford R., Oloyede A., Xiao Y. The microRNA expression signature on modified titanium implant surfaces influences genetic mechanisms leading to osteogenic differentiation. Acta Biomater 2012, 8:3516-3523.
30. Olivares-Navarrete R., Hyzy S., Wieland M., Boyan B.D., Schwartz Z. The roles of Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell maturation state in osteogenesis on microstructured titanium surfaces. Biomaterials 2010, 31:2015-2024.
31. Schernthaner M., Reisinger B., Wolinski H., Kohlwein S.D., Trantina-Yates A., Fahrner M., et al. Nanopatterned polymer substrates promote endothelial proliferation by initiation of β-catenin transcriptional signaling. Acta Biomater 2012, 8:2953-2962.
32. 2 nanotube layers. Colloids Surf B Biointerfaces 2012, 93:135-142.
33. Liu N., Shi S., Deng M., Tang L., Zhang G., Ding B., et al. High levels of β-catenin signaling reduce osteogenic differentiation of stem cells in inflammatory microenvironments through inhibition of the noncanonical Wnt pathway. J Bone Miner Res 2011, 26:2082-2095.
34. Bodine P.V. Wnt signaling control of bone cell apoptosis. Cell Res 2008, 18:248-253.
35. Xia J.J., Pei L.B., Zhuang J.P., Ji Y., Xu G.P., Zhang Z.P., et al. Celecoxib inhibits β-catenin-dependent survival of the human osteosarcoma MG-63 cell line. J Int Med Res 2010, 38:1294-1304.
36. Bonewald L.F., Johnson M.L. Osteocytes, mechanosensing and Wnt signaling. Bone 2008, 42:606-615.
37. 2 nanotube diameter directs cell fate. Nano Lett 2007, 7:1686-1691.
38. O'Brien W.T., Harper A.D., Jove F., Woodgett J.R., Maretto S., Piccolo S., et al. Glycogen synthase kinase-3β haploinsufficiency mimics the behavioral and molecular effects of lithium. J Neurosci 2004, 24:6791-6798.
39. Galli C, Piemontese M, Lumetti S, Manfredi E, Macaluso GM, Passeri G. GSK3b-inhibitor lithium chloride enhances activation of Wnt canonical signaling and osteoblast differentiation on hydrophilic titanium surfaces. Clin Oral Implants Res doi:10.1111/j.1600-0501.2012.02488.x, in press.
40. Han P., Wu C., Chang J., Xiao Y. The cementogenic differentiation of periodontal ligament cells via the activation of Wnt/β-catenin signalling pathway by Li+ ions released from bioactive scaffolds. Biomaterials 2012, 33:6370-6379.
41. Zhao L., Wang H., Huo K., Cui L., Zhang W., Ni H., et al. Antibacterial nano-structured titania coating incorporated with silver nanoparticles. Biomaterials 2011, 32:5706-5716.