-
1
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. Cancer J. Clin. 59, 225-249 (2009).
-
(2009)
Cancer J. Clin.
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
2
-
-
33847638137
-
Estimates of the cancer incidence and mortality in Europe in 2006
-
Ferlay J, Autier P, Boniol M, Heanue M, Colombet M, Boyle P. Estimates of the cancer incidence and mortality in Europe in 2006. Ann. Oncol. 18(3), 581-592 (2007).
-
(2007)
Ann. Oncol.
, vol.18
, Issue.3
, pp. 581-592
-
-
Ferlay, J.1
Autier, P.2
Boniol, M.3
Heanue, M.4
Colombet, M.5
Boyle, P.6
-
3
-
-
0033526386
-
Rising incidence of renal cell cancer in the United States
-
Chow WH, Devesa SS, Warren JL, Fraumeni JF Jr. Rising incidence of renal cell cancer in the United States. JAMA 281, 1628-1631 (1999).
-
(1999)
JAMA
, vol.281
, pp. 1628-1631
-
-
Chow, W.H.1
Devesa, S.S.2
Warren, J.L.3
Fraumeni Jr., J.F.4
-
4
-
-
33744520301
-
Surgical management of low-stage renal cell carcinoma: Technology does not supersede biology
-
Hollingsworth JM, Miller DC, Dunn RL et al. Surgical management of low-stage renal cell carcinoma: Technology does not supersede biology. Urology 67, 1175-1180 (2006).
-
(2006)
Urology
, vol.67
, pp. 1175-1180
-
-
Hollingsworth, J.M.1
Miller, D.C.2
Dunn, R.L.3
-
5
-
-
1542267903
-
Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy
-
Leibovich BC, Blute ML, Cheville JC et al. Nephron sparing surgery for appropriately selected renal cell carcinoma between 4 and 7 cm results in outcome similar to radical nephrectomy. J. Urol. 171, 1066-1070 (2004).
-
(2004)
J. Urol.
, vol.171
, pp. 1066-1070
-
-
Leibovich, B.C.1
Blute, M.L.2
Cheville, J.C.3
-
6
-
-
47149114026
-
Renal cell cancer stage migration: Analysis of the National Cancer Data Base
-
Kane CJ, Mallin K, Ritchey J, Cooperberg MR, Carroll PR. Renal cell cancer stage migration: Analysis of the National Cancer Data Base. Cancer 113, 78-83 (2008).
-
(2008)
Cancer
, vol.113
, pp. 78-83
-
-
Kane, C.J.1
Mallin, K.2
Ritchey, J.3
Cooperberg, M.R.4
Carroll, P.R.5
-
7
-
-
0003998061
-
-
(8th Edition). Lippincott Williams and Wilkins, Philadelphia, PA, USA
-
DeVita VT Jr, Hellman S, Rosenberg SA. Cancer Principles and Practice of Oncology (8th Edition). Lippincott Williams and Wilkins, Philadelphia, PA, USA (2008).
-
(2008)
Cancer Principles and Practice of Oncology
-
-
DeVita Jr., V.T.1
Hellman, S.2
Rosenberg, S.A.3
-
8
-
-
0035868654
-
Improved prognostication of renal cell carcinoma using an integrated staging system
-
Zisman A, Pantuck AJ, Dorey F et al. Improved prognostication of renal cell carcinoma using an integrated staging system. J. Clin. Oncol. 19, 1649-1657 (2001).
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 1649-1657
-
-
Zisman, A.1
Pantuck, A.J.2
Dorey, F.3
-
9
-
-
0036895290
-
Risk group assessment and clinical outcome algorithm to predict the natural history of patients with surgically resected renal cell carcinoma
-
nFirst to describe the UCLA integrated scoring system to predict risk of relapse after surgery in renal cell carcinoma (RCC) patients
-
Zisman A, Pantuck AJ, Wieder J et al. Risk group assessment and clinical outcome algorithm to predict the natural history of patients with surgically resected renal cell carcinoma. J. Clin. Oncol. 20, 4559-4566 (2002). nFirst to describe the UCLA integrated scoring system to predict risk of relapse after surgery in renal cell carcinoma (RCC) patients.
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 4559-4566
-
-
Zisman, A.1
Pantuck, A.J.2
Wieder, J.3
-
10
-
-
0036893892
-
An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: The SSIGN score
-
nDemonstrated that tumor stage, tumor size, nuclear grade and histologic tumor necrosis could predict progression to metastatic RCC in patients with clear cell RCC
-
Frank I, Blute ML, Cheville JC, Lohse CM, Weaver AL, Zincke H. An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: The SSIGN score. J. Urol. 168, 2395-2400 (2002). nDemonstrated that tumor stage, tumor size, nuclear grade and histologic tumor necrosis could predict progression to metastatic RCC in patients with clear cell RCC.
-
(2002)
J. Urol.
, vol.168
, pp. 2395-2400
-
-
Frank, I.1
Blute, M.L.2
Cheville, J.C.3
Lohse, C.M.4
Weaver, A.L.5
Zincke, H.6
-
11
-
-
0037379172
-
Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma: A stratification tool for prospective clinical trials
-
nForms the basis for development of the Leibovich score used in some of the ongoing adjuvant trials
-
Leibovich BC, Blute ML, Cheville JC et al. Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma: A stratification tool for prospective clinical trials. Cancer 97, 1663-1671 (2003). nForms the basis for development of the Leibovich score used in some of the ongoing adjuvant trials.
-
(2003)
Cancer
, vol.97
, pp. 1663-1671
-
-
Leibovich, B.C.1
Blute, M.L.2
Cheville, J.C.3
-
12
-
-
58149170711
-
The 'stage, size, grade and necrosis' score is more accurate than the University of California Los Angeles Integrated Staging System for predicting cancer-specific survival in patients with clear cell renal cell carcinoma
-
Ficarra V, Novara G, Galfano A et al. The 'stage, size, grade and necrosis' score is more accurate than the University of California Los Angeles Integrated Staging System for predicting cancer-specific survival in patients with clear cell renal cell carcinoma. BJU Int. 103, 165-170 (2009).
-
(2009)
BJU Int
, vol.103
, pp. 165-170
-
-
Ficarra, V.1
Novara, G.2
Galfano, A.3
-
13
-
-
0027173443
-
Interferon alfa-2a in advanced renal cell carcinoma: Treatment results and survival in 159 patients with long-term follow-up
-
Minasian LM, Motzer RJ, Gluck L, Mazumdar M, Vlamis V, Krown SE. Interferon alfa-2a in advanced renal cell carcinoma: Treatment results and survival in 159 patients with long-term follow-up. J. Clin. Oncol. 11, 1368-1375 (1993).
-
(1993)
J. Clin. Oncol.
, vol.11
, pp. 1368-1375
-
-
Minasian, L.M.1
Motzer, R.J.2
Gluck, L.3
Mazumdar, M.4
Vlamis, V.5
Krown, S.E.6
-
14
-
-
0033847587
-
Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma
-
Fisher RI, Rosenberg SA, Fyfe G. Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma. Cancer J. Sci. Am. 6(Suppl. 1), S55-S57 (2000).
-
(2000)
Cancer J. Sci. Am.
, vol.6
, Issue.SUPPL. 1
-
-
Fisher, R.I.1
Rosenberg, S.A.2
Fyfe, G.3
-
15
-
-
0038514165
-
Phase III study of interferon alfa-NL as adjuvant treatment for resectable renal cell carcinoma: An Eastern Cooperative Oncology Group/Intergroup trial
-
Messing EM, Manola J, Wilding G et al. Phase III study of interferon alfa-NL as adjuvant treatment for resectable renal cell carcinoma: An Eastern Cooperative Oncology Group/Intergroup trial. J. Clin. Oncol. 21, 1214-1222 (2003).
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 1214-1222
-
-
Messing, E.M.1
Manola, J.2
Wilding, G.3
-
16
-
-
0035863285
-
Interferon adjuvant to radical nephrectomy in Robson stages II and III renal cell carcinoma: A multicentric randomized study
-
Pizzocaro G, Piva L, Colavita M et al. Interferon adjuvant to radical nephrectomy in Robson stages II and III renal cell carcinoma: A multicentric randomized study. J. Clin. Oncol. 19, 425-431 (2001).
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 425-431
-
-
Pizzocaro, G.1
Piva, L.2
Colavita, M.3
-
17
-
-
0041411517
-
Adjuvant high-dose bolus interleukin-2 for patients with high-risk renal cell carcinoma: A Cytokine Working Group randomized trial
-
Clark JI, Atkins MB, Urba WJ et al. Adjuvant high-dose bolus interleukin-2 for patients with high-risk renal cell carcinoma: A Cytokine Working Group randomized trial. J. Clin. Oncol. 21, 3133-3140 (2003).
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 3133-3140
-
-
Clark, J.I.1
Atkins, M.B.2
Urba, W.J.3
-
18
-
-
33749063421
-
Adjuvant subcutaneous interleukin-2 in patients with resected renal cell carcinoma: A pilot study
-
Majhail NS, Wood L, Elson P, Finke J, Olencki T, Bukowski RM. Adjuvant subcutaneous interleukin-2 in patients with resected renal cell carcinoma: A pilot study. Clin. Genitourin. Cancer 5, 50-56 (2006).
-
(2006)
Clin. Genitourin. Cancer
, vol.5
, pp. 50-56
-
-
Majhail, N.S.1
Wood, L.2
Elson, P.3
Finke, J.4
Olencki, T.5
Bukowski, R.M.6
-
19
-
-
0030006748
-
Adjuvant immunotherapy treatment of renal carcinoma patients with autologous tumor cells and bacillus Calmette-Guèrin: Five-year results of a prospective randomized study
-
Galligioni E, Quaia M, Merlo A et al. Adjuvant immunotherapy treatment of renal carcinoma patients with autologous tumor cells and bacillus Calmette-Guèrin: Five-year results of a prospective randomized study. Cancer 77, 2560-2566 (1996).
-
(1996)
Cancer
, vol.77
, pp. 2560-2566
-
-
Galligioni, E.1
Quaia, M.2
Merlo, A.3
-
20
-
-
10744230275
-
Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: Phase III, randomised controlled trial
-
Jocham D, Richter A, Hoffmann L et al. Adjuvant autologous renal tumour cell vaccine and risk of tumour progression in patients with renal-cell carcinoma after radical nephrectomy: Phase III, randomised controlled trial. Lancet 363, 594-599 (2004).
-
(2004)
Lancet
, vol.363
, pp. 594-599
-
-
Jocham, D.1
Richter, A.2
Hoffmann, L.3
-
21
-
-
46749085802
-
An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: A multicentre, open-label, randomised Phase III trial
-
C-100-112 RCC Study Group.
-
Wood C, Srivastava P, Bukowski R et al.; C-100-112 RCC Study Group. An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: A multicentre, open-label, randomised Phase III trial. Lancet 372, 145-154 (2008).
-
(2008)
Lancet
, vol.372
, pp. 145-154
-
-
Wood, C.1
Srivastava, P.2
Bukowski, R.3
-
22
-
-
0023473331
-
Adjuvant medroxyprogesterone acetate to radical nephrectomy in renal cancer: 5-year results of a prospective randomized study
-
Pizzocaro G, Piva L, Di Fronzo G et al. Adjuvant medroxyprogesterone acetate to radical nephrectomy in renal cancer: 5-year results of a prospective randomized study. J. Urol. 138, 1379-1381 (1987).
-
(1987)
J. Urol.
, vol.138
, pp. 1379-1381
-
-
Pizzocaro, G.1
Piva, L.2
Di Fronzo, G.3
-
23
-
-
20144388609
-
Adjuvant treatment with interleukin-2- And interferon-Alpha2a-based chemoimmunotherapy in renal cell carcinoma post tumour nephrectomy: Results of a prospectively randomised trial of the German Cooperative Renal Carcinoma hemoimmunotherapy Group (DGCIN
-
Atzpodien J, Schmitt E, Gertenbach U et al. Adjuvant treatment with interleukin-2- And interferon-Alpha2a-based chemoimmunotherapy in renal cell carcinoma post tumour nephrectomy: Results of a prospectively randomised trial of the German Cooperative Renal Carcinoma hemoimmunotherapy Group (DGCIN). Br. J. Cancer 92, 843-846 (2005).
-
(2005)
Br. J. Cancer
, vol.92
, pp. 843-846
-
-
Atzpodien, J.1
Schmitt, E.2
Gertenbach, U.3
-
24
-
-
27744561283
-
Renal cell carcinoma: Durrent status and future prospects
-
Drucker BJ. Renal cell carcinoma: Durrent status and future prospects. Cancer Treat. Rev. 31, 536-545 (2005).
-
(2005)
Cancer Treat. Rev.
, vol.31
, pp. 536-545
-
-
Drucker, B.J.1
-
25
-
-
0027240519
-
Identification of the von Hippel-Lindau disease tumor suppressor gene
-
Latif F, Tory K, Gnarra J et al. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science 260, 1317-1320 (1993).
-
(1993)
Science
, vol.260
, pp. 1317-1320
-
-
Latif, F.1
Tory, K.2
Gnarra, J.3
-
26
-
-
73349089306
-
Analysis of VHL gene alterations and their relationship to clinical parameters in sporadic conventional renal cell carcinoma
-
Young AC, Craven RA, Cohen D et al. Analysis of VHL gene alterations and their relationship to clinical parameters in sporadic conventional renal cell carcinoma. Clin. Cancer Res. 15(24), 7582 (2009).
-
(2009)
Clin. Cancer Res.
, vol.15
, Issue.24
, pp. 7582
-
-
Young, A.C.1
Craven, R.A.2
Cohen, D.3
-
27
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
n nExplains how levels of hypoxia inducible factor (HIF)-A subunits are regulated by VHL and is a seminal paper in HIF biology
-
Maxwell PH, Wiesener MS, Chang GW et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399(6733), 271-275 (1999). n nExplains how levels of hypoxia inducible factor (HIF)-A subunits are regulated by VHL and is a seminal paper in HIF biology.
-
(1999)
Nature
, vol.399
, Issue.6733
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
-
28
-
-
0030816109
-
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
-
Maxwell PH, Dachs GU, Gleadle JM et al. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc. Natl Acad. Sci. USA 94, 8104-8109 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 8104-8109
-
-
Maxwell, P.H.1
Dachs, G.U.2
Gleadle, J.M.3
-
29
-
-
0035394516
-
Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1a in clear cell renal carcinomas
-
Wiesner M, Munchenhagen P, Berger I et al. Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1a in clear cell renal carcinomas. Cancer Res. 61, 5215-5222 (2001).
-
(2001)
Cancer Res
, vol.61
, pp. 5215-5222
-
-
Wiesner, M.1
Munchenhagen, P.2
Berger, I.3
-
30
-
-
0034676331
-
Up-regulation of hypoxia-inducible factors HIF-1a and HIF-2a under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function
-
Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate K. Up-regulation of hypoxia-inducible factors HIF-1a and HIF-2a under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function. Oncogene 19, 5435-5443 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 5435-5443
-
-
Krieg, M.1
Haas, R.2
Brauch, H.3
Acker, T.4
Flamme, I.5
Plate, K.6
-
31
-
-
0037093238
-
Expression of hypoxia-inducible factors in human renal cancer: Relationship to angiogenesis and to the von Hippel-Lindau gene mutation
-
Turner KJ, Moore JW, Jones A et al. Expression of hypoxia-inducible factors in human renal cancer: Relationship to angiogenesis and to the von Hippel-Lindau gene mutation. Cancer Res. 62, 2957-2961 (2002).
-
(2002)
Cancer Res
, vol.62
, pp. 2957-2961
-
-
Turner, K.J.1
Moore, J.W.2
Jones, A.3
-
33
-
-
33749451610
-
Molecular pathways in renal cell carcinoma - rationale for targeted treatment
-
Kim WY, Kaelin WG Jr. Molecular pathways in renal cell carcinoma - rationale for targeted treatment. Semin. Oncol. 33(5), 588-595 (2006).
-
(2006)
Semin. Oncol.
, vol.33
, Issue.5
, pp. 588-595
-
-
Kim, W.Y.1
Kaelin Jr., W.G.2
-
34
-
-
84859844667
-
Targeted therapeutic strategies for the management of renal cell carcinoma
-
nUseful review of current and future targeted therapies in RCC
-
Singer EA, Gupta GN, Srinivasan R. Targeted therapeutic strategies for the management of renal cell carcinoma. Curr. Opin Oncol. 24(3), 284-290 (2012). nUseful review of current and future targeted therapies in RCC.
-
(2012)
Curr. Opin Oncol.
, vol.24
, Issue.3
, pp. 284-290
-
-
Singer, E.A.1
Gupta, G.N.2
Srinivasan, R.3
-
35
-
-
0142219359
-
Pathobiology, prognosis, and targeted therapy for renal cell carcinoma: Exploiting the hypoxia-induced pathway
-
Pantuck AJ, Zeng G, Belldegrun AS, Figlin RA. Pathobiology, prognosis, and targeted therapy for renal cell carcinoma: Exploiting the hypoxia-induced pathway. Clin. Cancer Res. 9, 4641-4652 (2003).
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 4641-4652
-
-
Pantuck, A.J.1
Zeng, G.2
Belldegrun, A.S.3
Figlin, R.A.4
-
36
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier B, Eisen T, Stadler WM et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N. Engl. J. Med. 356, 125-134 (2007).
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
-
37
-
-
33846181370
-
Sunitinib versus interferon-A in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P et al. Sunitinib versus interferon-A in metastatic renal-cell carcinoma. N. Engl. J. Med. 356, 115-124 (2007).
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
38
-
-
37349080670
-
Bevacizumab plus interferon-A-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind Phase III trial
-
Escudier B, Pluzanska A, Koralewski P et al. Bevacizumab plus interferon-A-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind Phase III trial. Lancet 370, 2103-2111 (2007).
-
(2007)
Lancet
, vol.370
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
-
39
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized Phase III trial
-
Sternberg CN, Davis ID, Mardiak J et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized Phase III trial. J. Clin. Oncol. 28, 1061-1068 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
-
40
-
-
0034654174
-
Modulation of hypoxia-inducible factor 1a expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
-
Zhong H, Chiles K, Feldser D et al. Modulation of hypoxia-inducible factor 1a expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics. Cancer Res. 60, 1541-1545 (2000).
-
(2000)
Cancer Res
, vol.60
, pp. 1541-1545
-
-
Zhong, H.1
Chiles, K.2
Feldser, D.3
-
41
-
-
0034050050
-
Loss of PTEN facilitates HIF-1-mediated gene expression
-
Zundel W, Schindler C, Haas-Kogan D et al. Loss of PTEN facilitates HIF-1-mediated gene expression. Genes Dev. 14, 391-396 (2000).
-
(2000)
Genes Dev
, vol.14
, pp. 391-396
-
-
Zundel, W.1
Schindler, C.2
Haas-Kogan, D.3
-
42
-
-
0035012605
-
HER2(neu) signaling increases the rate of hypoxia-inducible factor 1a (HIF-1a) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
-
Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL. HER2(neu) signaling increases the rate of hypoxia-inducible factor 1a (HIF-1a) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol. Cell Biol. 21, 3995-4004 (2001).
-
(2001)
Mol. Cell Biol.
, vol.21
, pp. 3995-4004
-
-
Laughner, E.1
Taghavi, P.2
Chiles, K.3
Mahon, P.C.4
Semenza, G.L.5
-
43
-
-
34249779568
-
Temsirolimus, interferon-A, or both for advanced renal cell carcinoma
-
Hudes G, Carducci M, Tomczak P et al. Temsirolimus, interferon-A, or both for advanced renal cell carcinoma. N. Engl. J. Med. 356, 2271-2281 (2007).
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
-
44
-
-
77956227464
-
Phase 3 trial of everolimus for metastatic renal cell carcinoma: Final results and analysis of prognostic factors
-
Motzer RJ, Escudier B, Oudard S et al. Phase 3 trial of everolimus for metastatic renal cell carcinoma: Final results and analysis of prognostic factors. Cancer 116, 4256-4265 (2010).
-
(2010)
Cancer
, vol.116
, pp. 4256-4265
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
45
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled Phase III trial
-
Motzer RJ, Escudier B, Oudard S et al. Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled Phase III trial. Lancet 372, 449-456 (2008).
-
(2008)
Lancet
, vol.372
, pp. 449-456
-
-
Motzer, R.J.1
Escudier, B.2
Oudard, S.3
-
46
-
-
44449143994
-
Carbonic anhydrase IX and renal cell carcinoma: Prognosis, response to systemic therapy, and future vaccine strategies
-
Shuch B, Li Z, Belldegrun AS. Carbonic anhydrase IX and renal cell carcinoma: Prognosis, response to systemic therapy, and future vaccine strategies. BJU Int. 101, 25-30 (2008).
-
(2008)
BJU Int.
, vol.101
, pp. 25-30
-
-
Shuch, B.1
Li, Z.2
Belldegrun, A.S.3
-
47
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Pàez-Ribes M, Allen E, Hudock J et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15(3), 220-231 (2009).
-
(2009)
Cancer Cell
, vol.15
, Issue.3
, pp. 220-231
-
-
Pàez-Ribes, M.1
Allen, E.2
Hudock, J.3
-
48
-
-
79955829332
-
Development of second-generation VEGFR tyrosine kinase inhibitors: Durrent status
-
Bhargava P, Robinson MO. Development of second-generation VEGFR tyrosine kinase inhibitors: Durrent status. Curr. Oncol. Rep. 13(2), 103-111 (2011).
-
(2011)
Curr. Oncol. Rep.
, vol.13
, Issue.2
, pp. 103-111
-
-
Bhargava, P.1
Robinson, M.O.2
-
49
-
-
79955072210
-
Exposure-response relationships in patients with metastatic renal cell carcinoma receiving sunitinib: Maintaining optimum efficacy in clinical practice
-
Ravaud A, Bello CL. Exposure-response relationships in patients with metastatic renal cell carcinoma receiving sunitinib: Maintaining optimum efficacy in clinical practice. Anticancer Drugs 22(5), 377-383 (2011).
-
(2011)
Anticancer Drugs
, vol.22
, Issue.5
, pp. 377-383
-
-
Ravaud, A.1
Bello, C.L.2
-
51
-
-
65949083992
-
Circulating biomarkers for vascular endothelial growth factor inhibitors in renal cell carcinoma
-
Zurita AJ, Jonasch E, Wu HK, Tran HT, Heymach JV. Circulating biomarkers for vascular endothelial growth factor inhibitors in renal cell carcinoma. Cancer 115, 2346-2354 (2009).
-
(2009)
Cancer
, vol.115
, pp. 2346-2354
-
-
Zurita, A.J.1
Jonasch, E.2
Wu, H.K.3
Tran, H.T.4
Heymach, J.V.5
-
52
-
-
80054993340
-
Biomarkers to predict response to sunitinib therapy and prognosis in metastatic renal cancer
-
Yuasa T, Takahashi S, Hataki K, Yonese J, Fukui I. Biomarkers to predict response to sunitinib therapy and prognosis in metastatic renal cancer. Cancer Sci. 102, 1949-1957 (2011).
-
(2011)
Cancer Sci
, vol.102
, pp. 1949-1957
-
-
Yuasa, T.1
Takahashi, S.2
Hataki, K.3
Yonese, J.4
Fukui, I.5
-
53
-
-
51749123391
-
Speeding up the evaluation of new agents in cancer
-
nGood review and explanation of the multiarm multistage (MAMS) trial design
-
Parmar MK. Speeding up the evaluation of new agents in cancer. J. Natl Cancer Inst. 100(17), 1204-1214 (2008). nGood review and explanation of the multiarm multistage (MAMS) trial design.
-
(2008)
J. Natl Cancer Inst.
, vol.100
, Issue.17
, pp. 1204-1214
-
-
Parmar, M.K.1
-
54
-
-
51449097507
-
STAMPEDE: Systemic Therapy for Advancing or Metastatic Prostate Cancer - A multi-Arm multi-stage randomised controlled trial
-
James ND, Sydes MR, Clarke NW et al. STAMPEDE: Systemic Therapy for Advancing or Metastatic Prostate Cancer - A multi-Arm multi-stage randomised controlled trial. Clin. Oncol. 20(8), 577-581 (2008).
-
(2008)
Clin. Oncol.
, vol.20
, Issue.8
, pp. 577-581
-
-
James, N.D.1
Sydes, M.R.2
Clarke, N.W.3
-
55
-
-
59249100332
-
Systemic therapy for advancing or metastatic prostate cancer (STAMPEDE): A multi-Arm, multistage randomized controlled trial
-
James ND, Sydes MR, Clarke NW et al. Systemic therapy for advancing or metastatic prostate cancer (STAMPEDE): A multi-Arm, multistage randomized controlled trial. BJU Int. 103(4), 464-469 (2009).
-
(2009)
BJU Int
, vol.103
, Issue.4
, pp. 464-469
-
-
James, N.D.1
Sydes, M.R.2
Clarke, N.W.3
-
56
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A et al. Abiraterone and increased survival in metastatic prostate cancer. N. Engl. J. Med. 364(21), 1995-2005 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, Issue.21
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
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