An outcome prediction model for patients with clear cell renal cell carcinoma treated with radical nephrectomy based on tumor stage, size, grade and necrosis: The SSIGN score

Journal of Urology

Volumn 168, Issue 6, 2002, Pages 2395-2400

  Frank, Igor ^a   Blute, Michael L ^a   Cheville, John C ^a   Lohse, Christine M ^a   Weaver, Amy L ^a   Zincke, Horst ^a  

^a MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

Carcinoma, renal cell; Treatment outcome, survival, nephrectomy

Indexed keywords

ADULT; ARTICLE; CANCER GRADING; CANCER SIZE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLEAR CELL CARCINOMA; CLINICAL FEATURE; FEMALE; FOLLOW UP; HUMAN; KIDNEY CARCINOMA; KIDNEY NECROSIS; MAJOR CLINICAL STUDY; MALE; NEPHRECTOMY; OUTCOMES RESEARCH; PRIORITY JOURNAL; SCORING SYSTEM; SURVIVAL RATE; TUMOR VOLUME;

EID: 0036893892     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(05)64153-5     Document Type: Article

References (24)

1. Gettman, M. T., Blute, M. L., Spotts, B., Bryant, S. C. and Zincke, H.: Pathologic staging of renal cell carcinoma: Significance of tumor classification with the 1997 TNM staging system. Cancer, 91: 354, 2001
2. Javidan, J., Stricker, H. J., Tamboli, P., Amin, M. B., Peabody, J. O., Deshpande, A. et al: Prognostic significance of the 1997 TNM classification of renal cell carcinoma. J Urol, 162: 1277, 1999
3. Frank, I., Blute, M., Weaver, A. and Zincke, H.: TNM staging alone is inadequate for predicting cancer-specific survival following radical nephrectomy for unilateral renal cell carcinoma. J Urol, suppl., 165: 185, abstract 768, 2001
4. Lau, W. K., Cheville, J. C., Blute, M. L., Weaver, A. L. and Zincke, H.: Prognostic features of pathologic stage T1 renal cell carcinoma after radical nephrectomy. Urology, 59: 532, 2002
5. Moch, H., Gasser, T., Amin, M. B., Torhorst, J., Sauter, G. and Mihatsch, M. J.: Prognostic utility of the recently recommended histologic classification and revised TNM staging system of renal cell carcinoma: A Swiss experience with 588 tumors. Cancer, 89: 604, 2000
6. Amin, M. B., Amin, M. B., Tamboli, P., Javidan, J., Stricker, H., de-Peralta Venturina, M. et al: Prognostic impact of histologic subtyping of adult renal epithelial neoplasms: An experience of 405 cases. Am J Surg Pathol, 26: 281, 2002
7. Storkel, S., Eble, J. N., Adlakha, K., Amin, M., Blute, M. L., Bostwick, D. G. et al: Classification of renal cell carcinoma: Workgroup No. 1. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC). Cancer, 80: 987, 1997
8. Sauerbrei, W. and Schumacher, M.: A bootstrap resampling procedure for model building: Application to the Cox regression model. Stat Med, 11: 2093, 1992
9. Ward, J. F., Blute, M. L., Cheville, J. C., Lohse, C. M., Weaver, A. L. and Zincke, H.: The influence of PNX/PN0 grouping in a multivariate setting for outcome models in patients with clear cell renal cell carcinoma. J Urol, 168: 56, 2002
10. Harrell, F. E., Jr., Lee, K. L. and Mark, D. B.: Multivariable prognostic models: Issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med, 15: 361, 1996
11. Charlson, M. E., Pompei, P., Ales, K. L. and MacKenzie, C. R.: A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis, 40: 373, 1987
12. Schoenfeld, D.: Chi-squared goodness-of-fit tests for the proportional hazards regression model. Biometrika, 67: 145, 1980
13. Grambsch, P. M. and Therneau, T. M.: Proportional hazards tests and diagnostics based on weighted residuals. Biometrika, 81: 515, 1994
14. Motzer, R. J., Mazumdar, M., Bacik, J., Berg, W., Amsterdam, A. and Ferrara, J.: Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J Clin Oncol, 07: 2530, 1999
15. Elson, P. J., Witte, R. S. and Trump, D. L.: Prognostic factors for survival in patients with recurrent or metastatic renal cell carcinoma. Canber Res, 48: 7310, 1988
16. Zisman, A., Pantuck, A. J., Dorey, F., Said, J. W., Shvarts, O., Quintanna, D. et al: Improved prognostication of renal cell carcinoma using an integrated staging system. J Clin Oncol, 19: 1649, 2001
17. Kattan, M. W., Reuter, V., Motzer, R. J., Katz, J. and Russo, P.: A postoperative prognostic nomogram for renal cell carcinoma. J Urol, 166: 63, 2001
18. Tsui, K.-H., Shvarts, O., Smith, R. B., Figlin, R. A., deKernion, J. B. and Belldegrun, A.: Prognostic indicators for renal cell carcinoma: A multivariate analysis of 643 patients using the revised 1997 TNM staging criteria. J Urol, 163: 1090, 2000
19. Mani, S., Todd, M. B., Katz, K. and Poo, W.-J.: Prognostic factors for survival in patients with metastatic renal cancer treated with biological response modifiers. J Urol, 154: 35, 1995
20. Zisman, A., Pantuck, A. J., Chao, D., Dorey, F., Said, J. W., Gitlitz, B. J. et al: Reevaluation of the 1997 TNM classification for renal cell carcinoma: T1 and T2 cutoff point at 4.5 rather than 7 cm. better correlates with clinical outcome. J Urol, 166: 54, 2001
21. Igarashi, T., Tobe, T., Nakatsu, H.-O., Suzuki, N., Murakami, S., Hamano, M. et al: The impact of a 4 cm. cutoff point for stratification of TiN0M0 renal cell carcinoma after radical nephrectomy. J Urol, 165: 1103, 2001
22. Cheville, J. C., Blute, M. L., Zincke, H., Lohse, C. M. and Weaver, A. L.: Stage pT1 conventional (clear cell) renal cell carcinoma: Pathological features associated with cancer specific survival. J Urol, 166: 453, 2001
23. Gelb, A. B.: Renal cell carcinoma: Current prognostic factors. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC). Cancer, 80: 981, 1997
24. Srigley, J. R., Hutter, R. V., Gelb, A. B., Henson, D. E., Kenney, G., King, B. F. et al: Current prognostic factors-renal cell carcinoma. Workgroup No. 4. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC). Cancer 80: 994, 1997