An improved behavioural assay demonstrates that ultrasound vocalizations constitute a reliable indicator of chronic cancer pain and neuropathic pain

Molecular Pain

Volumn 6, Issue , 2010, Pages

  Kurejova, Martina ^a   Nattenmüller, Ulrike ^a   Hildebrandt, Ullrich ^a   Selvaraj, Deepitha ^a   Stösser, Sebastian ^a   Kuner, Rohini ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; FENTANYL; GABAPENTIN;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSAY; CANCER PAIN; CHRONIC PAIN; CONTROLLED STUDY; DISEASE COURSE; DISEASE DURATION; DRUG EFFECT; EVOKED RESPONSE; FEMALE; MALE; MOUSE; NEUROPATHIC PAIN; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN ASSESSMENT; PAIN PARAMETERS; PRIORITY JOURNAL; ULTRASOUND VOCALIZATION; VOCALIZATION; ANIMAL; CHRONIC DISEASE; METHODOLOGY; NEOPLASM; NEURALGIA; PATHOLOGY; ULTRASOUND;

ANIMALS; CHRONIC DISEASE; FEMALE; MALE; MICE; NEOPLASMS; NEURALGIA; PAIN MEASUREMENT; ULTRASONICS;

EID: 77952922701     PISSN: 17448069     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-8069-6-18     Document Type: Article

References (25)

1. Portenoy RK, Lesage P. Management of cancer pain. Lancet 1999, 353:1695-1700. 10.1016/S0140-6736(99)01310-0, 10335806.
2. Honore P, Mantyh PW. Bone cancer pain: from mechanism to model to therapy. Pain Med 2000, 1:303-9. 10.1046/j.1526-4637.2000.00047.x, 15101876.
3. Vickers ER, Cousins MJ. Neuropathic orofacial pain part 1--prevalence and pathophysiology. Aust Endod J 2000, 26:19-26. 10.1111/j.1747-4477.2000.tb00146.x, 11359293.
4. Jensen TS, Gottrup H, Sindrup SH, Bach FW. The clinical picture of neuropathic pain. Eur J Pharmacol 2001, 429:1-11. 10.1016/S0014-2999(01)01302-4, 11698022.
5. King T, Vera-Portocarrero L, Gutierrez T, Vanderah TW, Dussor G, Lai J, Fields HL, Porreca F. Unmasking the tonic-aversive state in neuropathic pain. Nat Neurosci 2009, 12:1364-6. 10.1038/nn.2407, 19783992.
6. Ko SW, Chatila T, Zhuo M. Contribution of CaMKIV to injury and fear-induced ultrasonic vocalizations in adult mice. Mol Pain 2005, 22:1-10.
7. Oliveira AR, Barros HM. Ultrasonic rat vocalizations during the formalin test: a measure of the affective dimension of pain?. Anesth Analg 2006, 102:832-9. 10.1213/01.ane.0000196530.72813.d9, 16492837.
8. Han JS, Bird GC, Li W, Jones J, Neugebauer V. Computerized analysis of audible and ultrasonic vocalizations of rats as a standardized measure of pain-related behavior. J Neurosci Methods 2005, 141:261-9. 10.1016/j.jneumeth.2004.07.005, 15661308.
9. Jourdan D, Ardid D, Chapuy E, Le Bars D, Eschalier A. Effect of analgesics on audible and ultrasonic pain-induced vocalization in the rat. Life Sc 1998, 63:1761-8.
10. Martino G, Perkins MN. Tactile-induced ultrasonic vocalization in the rat: a novel assay to assess anti-migraine therapies in vivo. Cephalalgia 2008, 28:723-33. 10.1111/j.1468-2982.2008.01582.x, 18498397.
11. Wallace VC, Norbury TA, Rice AS. Ultrasound vocalisation by rodents does not correlate with behavioural measures of persistent pain. Eur J Pain 2005, 9:445-52. 10.1016/j.ejpain.2004.10.006, 15979025.
12. Jourdan D, Ardid D, Eschalier A. Analysis of ultrasonic vocalisation does not allow chronic pain to be evaluated in rats. Pain 2002, 95:165-73. 10.1016/S0304-3959(01)00394-3, 11790479.
13. Williams WO, Riskin DK, Mott AK. Ultrasonic sound as an indicator of acute pain in laboratory mice. J Am Assoc Lab Anim Sci 2008, 47:8-10. 2652617, 18210991.
14. Wöhr M, Borta A, Schwarting RK. Overt behavior and ultrasonic vocalization in a fear conditioning paradigm: a dose-response study in the rat. Neurobiol Learn Mem 2005, 84:228-40. 10.1016/j.nlm.2005.07.004, 16115784.
15. Litvin Y, Blanchard DC, Blanchard RJ. Rat 22 kHz ultrasonic vocalizations as alarm cries. Behav Brain Res 2007, 182:166-72. 10.1016/j.bbr.2006.11.038, 17173984.
16. Jelen P, Soltysik S, Zagrodzka J. 22-kHz ultrasonic vocalization in rats as an index of anxiety but not fear: behavioral and pharmacological modulation of affective state. Behav Brain Res 2003, 141:63-72. 10.1016/S0166-4328(02)00321-2, 12672560.
17. Blanchard RJ, Blanchard DC, Agullana R, Weiss SM. Twenty-two kHz alarm cries to presentation of a predator, by laboratory rats living in visible burrow systems. Physiol Behav 1991, 50:967-72. 10.1016/0031-9384(91)90423-L, 1805287.
18. Cain DM, Wacnik PW, Turner M, Wendelschafer-Crabb G, Kennedy WR, Wilcox GL, Simone DA. Functional interactions between tumor and peripheral nerve: changes in excitability and morphology of primary afferent fibers in a murine model of cancer pain. J Neurosci 2001, 21:9367-76.
19. Schweizerhof M, Stösser S, Kurejova M, Njoo C, Gangadharan V, Agarwal N, Schmelz M, Bali KK, Michalski CW, Brugger S, Dickenson A, Simone DA, Kuner R. Hematopoietic colony-stimulating factors mediate tumor-nerve interactions and bone cancer pain. Nat Med 2009, 15:802-7. 10.1038/nm.1976, 19525966.
20. Decosterd I, Woolf CJ. Spared nerve injury: an animal model of persistent peripheral neuropathic pain. Pain 2000, 87:149-58. 10.1016/S0304-3959(00)00276-1, 10924808.
21. Paix A, Coleman A, Lees J, Grigson J, Brooksbank M, Thorne D, Ashby M. Subcutaneous fentanyl and sufentanil infusion substitution for morphine intolerance in cancer pain management. Pain 1995, 63:263-9. 10.1016/0304-3959(95)00084-6, 8628593.
22. El Mouedden M, Meert TF. The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain. Pharmacol Biochem Behav 2007, 87:30-40. 10.1016/j.pbb.2007.03.017, 17521715.
23. Jensen TS, Madsen CS, Finnerup NB. Pharmacology and treatment of neuropathic pains. Curr Opin Neurol 2009, 22:467-74. 10.1097/WCO.0b013e3283311e13, 19741531.
24. Omori Y, Kagaya K, Enomoto R, Sasaki A, Andoh T, Nojima H, Takahata H, Kuraishi Y. A mouse model of sural nerve injury-induced neuropathy: gabapentin inhibits pain-related behaviors and the hyperactivity of wide-dynamic range neurons in the dorsal horn. J Pharmacol Sci 2009, 109:532-9. 10.1254/jphs.08319FP, 19346671.
25. Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin C, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, Reeh P, Kunos G, Kress M, Lutz B, Woolf CJ, Kuner R. Nociceptor-specific conditional gene deletion reveals that cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors. Nat Neurosci 2007, 10:870-9. 10.1038/nn1916, 2234438, 17558404.