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Volumn 14, Issue 5, 2000, Pages 715-728

Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression

Author keywords

Affinity; Ion gradients; Plasma membrane targeting; Translocation; Turnover rate

Indexed keywords

COCAINE; DOPAMINE; DOPAMINE TRANSPORTER;

EID: 0034117176     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.14.5.715     Document Type: Article
Times cited : (59)

References (33)
  • 3
    • 0028140473 scopus 로고
    • Pharmacotherapy of cocaine abuse: Preclinical development
    • Witkin, J. M. (1994) Pharmacotherapy of cocaine abuse: preclinical development. Neurosci. Biobehav. Rev. 18, 121-142
    • (1994) Neurosci. Biobehav. Rev. , vol.18 , pp. 121-142
    • Witkin, J.M.1
  • 4
    • 0028914467 scopus 로고
    • Molecular mechanisms of drug reinforcement and addiction
    • Self, D. W., and Nestler, E. J. (1995) Molecular mechanisms of drug reinforcement and addiction. Annu. Rev. Neurosci. 18, 463-495
    • (1995) Annu. Rev. Neurosci. , vol.18 , pp. 463-495
    • Self, D.W.1    Nestler, E.J.2
  • 5
    • 0026671035 scopus 로고
    • +: Uptake and toxicity in nonneuronal COS cells expressing dopamine transporter cDNA
    • +: uptake and toxicity in nonneuronal COS cells expressing dopamine transporter cDNA. Ann. Neurol. 32, 109-111
    • (1992) Ann. Neurol. , vol.32 , pp. 109-111
    • Kitayama, S.1    Shimada, S.2    Uhl, R.G.3
  • 6
    • 0027454020 scopus 로고
    • Dopamine transporter expression confers cytotoxicity to low doses of the Parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium
    • Pifl, C., Giros, B., and Caron, M. G. (1993) Dopamine transporter expression confers cytotoxicity to low doses of the Parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium. J. Neurosci. 13, 4246-4253
    • (1993) J. Neurosci. , vol.13 , pp. 4246-4253
    • Pifl, C.1    Giros, B.2    Caron, M.G.3
  • 7
    • 0023265754 scopus 로고
    • Cocaine receptors on dopamine transporters are related to self-administration of cocaine
    • Ritz, M. C., Lamb, R. J., Goldberg, S. R., and Kuhar, M. J. (1987) Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237, 1219-1223
    • (1987) Science , vol.237 , pp. 1219-1223
    • Ritz, M.C.1    Lamb, R.J.2    Goldberg, S.R.3    Kuhar, M.J.4
  • 8
    • 0024460030 scopus 로고
    • Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys
    • Bergman, J., Madras, B. K., Johnson, S. E., and Spealman, R. D. (1989) Effects of cocaine and related drugs in nonhuman primates. III. Self-administration by squirrel monkeys. J. Pharmacol. Exp. Ther. 251, 150-155
    • (1989) J. Pharmacol. Exp. Ther. , vol.251 , pp. 150-155
    • Bergman, J.1    Madras, B.K.2    Johnson, S.E.3    Spealman, R.D.4
  • 10
    • 0026330894 scopus 로고
    • Cloning and expression of a cocaine-sensitive rat dopamine transporter
    • Kilty, J. E., Lorang, D., and Amara, S. G. (1991) Cloning and expression of a cocaine-sensitive rat dopamine transporter. Science 254, 578-579
    • (1991) Science , vol.254 , pp. 578-579
    • Kilty, J.E.1    Lorang, D.2    Amara, S.G.3
  • 11
    • 0028535116 scopus 로고
    • Neurotransmitter transporters: Three important gene families for neuronal function
    • Uhl, G. R., and Johnson, P. S. (1994) Neurotransmitter transporters: three important gene families for neuronal function. J. Exp. Biol. 196, 229-236
    • (1994) J. Exp. Biol. , vol.196 , pp. 229-236
    • Uhl, G.R.1    Johnson, P.S.2
  • 12
    • 0028341658 scopus 로고
    • Delineation of discrete domains for substrate cocaine and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters
    • Giros, B., Wang, Y.-M., Suter, S., McLeskey, S. B., Pifl, C., and Caron, M. G. (1994) Delineation of discrete domains for substrate cocaine and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters. J. Biol. Chem. 269, 15985-15988
    • (1994) J. Biol. Chem. , vol.269 , pp. 15985-15988
    • Giros, B.1    Wang, Y.-M.2    Suter, S.3    McLeskey, S.B.4    Pifl, C.5    Caron, M.G.6
  • 13
    • 0028577297 scopus 로고
    • Chimeric dopaminenorepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium
    • Buck, K. J., and Amara, S. G. (1994) Chimeric dopaminenorepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium. Proc. Natl. Acad. Sci. USA 91, 12584-12588
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 12584-12588
    • Buck, K.J.1    Amara, S.G.2
  • 14
    • 0029560345 scopus 로고
    • Structural domains of catecholamine transporter chimeras involved in selective inhibition by antidepressants and psychomotor stimulants
    • Buck, K. J., and Amara, S. G. (1995) Structural domains of catecholamine transporter chimeras involved in selective inhibition by antidepressants and psychomotor stimulants. Mol. Pharmacol. 48, 1030-1037
    • (1995) Mol. Pharmacol. , vol.48 , pp. 1030-1037
    • Buck, K.J.1    Amara, S.G.2
  • 15
    • 0026722234 scopus 로고
    • Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding
    • Kitayama, S., Shimada, S., Xu, H., Markham, L., Donovan, D. M., and Uhl, G. R. (1992) Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding. Proc. Natl. Acad. Sci. USA 89, 7782-7785
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7782-7785
    • Kitayama, S.1    Shimada, S.2    Xu, H.3    Markham, L.4    Donovan, D.M.5    Uhl, G.R.6
  • 17
    • 0000882208 scopus 로고
    • Hypothesis about the function of membrane-buried proline residues in transport proteins
    • Brandl, C. J., and Deber, C. M. (1986) Hypothesis about the function of membrane-buried proline residues in transport proteins. Proc. Natl. Acad. Sci. USA 83, 917-921
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 917-921
    • Brandl, C.J.1    Deber, C.M.2
  • 18
    • 0018110116 scopus 로고
    • Prediction of the secondary structure of proteins from their amino acid sequence
    • Chou, P. Y., and Fasman, G. D. (1978) Prediction of the secondary structure of proteins from their amino acid sequence. Adv. Enzymol. Relat. Areas Mol. Biol. 47, 45-148
    • (1978) Adv. Enzymol. Relat. Areas Mol. Biol. , vol.47 , pp. 45-148
    • Chou, P.Y.1    Fasman, G.D.2
  • 19
    • 0025292355 scopus 로고
    • Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy
    • Henderson, R., Baldwin, J. M., Ceska, T. A., Zemlin, F., Beckmann, E., and Downing, K. H. (1990) Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy. J. Mol. Biol. 213, 899-929
    • (1990) J. Mol. Biol. , vol.213 , pp. 899-929
    • Henderson, R.1    Baldwin, J.M.2    Ceska, T.A.3    Zemlin, F.4    Beckmann, E.5    Downing, K.H.6
  • 20
    • 0024278714 scopus 로고
    • Helix geometry in proteins
    • Barlow, D. J., and Thornton, J. M. (1988) Helix geometry in proteins. J. Mol. Biol. 201, 601-619
    • (1988) J. Mol. Biol. , vol.201 , pp. 601-619
    • Barlow, D.J.1    Thornton, J.M.2
  • 21
    • 0025782832 scopus 로고
    • Proline kinks in transmembrane alpha-helices
    • Von Heijne, G. (1991) Proline kinks in transmembrane alpha-helices. J. Mol. Biol 218, 499-503
    • (1991) J. Mol. Biol , vol.218 , pp. 499-503
    • Von Heijne, G.1
  • 23
    • 0024713825 scopus 로고
    • A hydrogen bonded chain in bacteriorhodopsin by computer modeling approach
    • Sankara-Ramakrishnan, R., and Vishveshwara, S. (1989) A hydrogen bonded chain in bacteriorhodopsin by computer modeling approach. J. Biomol. Strut, Dyn. 7, 187-205
    • (1989) J. Biomol. Strut, Dyn. , vol.7 , pp. 187-205
    • Sankara-Ramakrishnan, R.1    Vishveshwara, S.2
  • 24
    • 0017429069 scopus 로고
    • Areas, volumes, packing and protein structure
    • Richards, F. M. (1977) Areas, volumes, packing and protein structure. Annu. Rev. Biophys. Bioengin. 6, 151-176
    • (1977) Annu. Rev. Biophys. Bioengin. , vol.6 , pp. 151-176
    • Richards, F.M.1
  • 25
    • 0026537558 scopus 로고
    • Proline residues in transmembrane helices of channel and transport proteins: A molecular modeling study
    • Sansom, M. S. (1992) Proline residues in transmembrane helices of channel and transport proteins: a molecular modeling study. Protein Engin. 5, 53-60
    • (1992) Protein Engin. , vol.5 , pp. 53-60
    • Sansom, M.S.1
  • 26
    • 0020476813 scopus 로고
    • A proton motive force transducer and its role in proton pumps, proton engines, tobacco mosaic virus assembly and hemoglobin allosterism
    • Dunker, A. K. (1982) A proton motive force transducer and its role in proton pumps, proton engines, tobacco mosaic virus assembly and hemoglobin allosterism. J. Theor. Biol. 97, 95-127
    • (1982) J. Theor. Biol. , vol.97 , pp. 95-127
    • Dunker, A.K.1
  • 27
    • 0027446493 scopus 로고
    • Neurotransmitter transporters: Recent progress
    • Amara, S. G., and Kuhar, M. J. (1995) Neurotransmitter transporters: recent progress. Annu. Rev. Neurosci. 16, 73-93
    • (1995) Annu. Rev. Neurosci. , vol.16 , pp. 73-93
    • Amara, S.G.1    Kuhar, M.J.2
  • 29
    • 0027417178 scopus 로고
    • Recognition of dopamine transporters of antipeptide antibodies
    • Vaughn, R., Uhl, G. R., and Kuhar, M. J. (1993) Recognition of dopamine transporters of antipeptide antibodies. Mol. Cell. Neurosci. 4, 209-215
    • (1993) Mol. Cell. Neurosci. , vol.4 , pp. 209-215
    • Vaughn, R.1    Uhl, G.R.2    Kuhar, M.J.3
  • 30
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (150) of an enzymatic reaction
    • Cheng, Y., and Prusoff, W. H. (1973) Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (150) of an enzymatic reaction. Biochem. Pharmacol. 22, 3099-108
    • (1973) Biochem. Pharmacol. , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 31
    • 0032801143 scopus 로고    scopus 로고
    • Dopamine transporter: Transmembrane phenylalanine mutations can selectively influence dopamine uptake and cocaine analog recognition
    • Lin, Z., Wang, W., Kopajtic, T., Revay, R. S., and Uhl, G. R. (1999) Dopamine transporter: transmembrane phenylalanine mutations can selectively influence dopamine uptake and cocaine analog recognition. Mol. Pharmacol. 56, 434-447
    • (1999) Mol. Pharmacol. , vol.56 , pp. 434-447
    • Lin, Z.1    Wang, W.2    Kopajtic, T.3    Revay, R.S.4    Uhl, G.R.5
  • 32
    • 0032488824 scopus 로고    scopus 로고
    • Stereochemical punctuation marks in protein structures: Glycine and proline containing helix stop signals
    • Gunasekaran, K., Nagarajaram, H. A., Ramakrishnan, C., and Balaram, P. (1998) Stereochemical punctuation marks in protein structures: glycine and proline containing helix stop signals. J. Mol. Biol. 275, 917-32
    • (1998) J. Mol. Biol. , vol.275 , pp. 917-932
    • Gunasekaran, K.1    Nagarajaram, H.A.2    Ramakrishnan, C.3    Balaram, P.4
  • 33
    • 0030962404 scopus 로고    scopus 로고
    • Identification of amino acid residues contributing to the pore of a P2X receptor
    • Rassendren, F., Buell, G., Newbolt, A., North, R. A., and Surprenant, A. (1997) Identification of amino acid residues contributing to the pore of a P2X receptor. EMBO J. 16, 3446-54
    • (1997) EMBO J. , vol.16 , pp. 3446-3454
    • Rassendren, F.1    Buell, G.2    Newbolt, A.3    North, R.A.4    Surprenant, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.