Role of the pyrrolidine ring of proline in determining the substrate specificity of cdc2 kinase or cdk5

Journal of Biochemistry

Volumn 122, Issue 2, 1997, Pages 409-414

  Ando, Shoji ^a   Ikuhara, Toshihiko ^b   Kamata, Tomoko ^b   Sasaki, Yasuharu ^b   Hisanaga, Shin Ichi ^c   Kishimoto, Takeo ^c   Ito, Hikaru ^d   Inagaki, Masaki ^d  

^a SAGA UNIVERSITY   (Japan)

^b ASAHI CHEMICAL INDUSTRY CO   (Japan)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^d AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

cdc2 kinase; cdk 5; Molecular dynamics and molecular mechanics simulations; Peptide synthesis; Phosphorylation

Indexed keywords

CYCLIN DEPENDENT KINASE; PROLINE; PROLINE DERIVATIVE; PYRROLIDINE DERIVATIVE; VIMENTIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

EID: 0030850429     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021768     Document Type: Article

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