Evaluation of an accurate mass approach for the simultaneous detection of drug and metabolite distributions via whole-body mass spectrometric imaging

Analytical Chemistry

Volumn 84, Issue 16, 2012, Pages 7158-7165

  Shahidi Latham, Sheerin K ^a   Dutta, Sucharita M ^b   Prieto Conaway, Maria C ^b   Rudewicz, Patrick J ^a  

^a GENENTECH INC   (United States)

^b Thermo Fisher Scientific   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURATE MASS; ANALYTES; DRUG CANDIDATES; DRUG DISCOVERY; DRUG DISTRIBUTION; IMAGING EXPERIMENTS; IMAGING MASS SPECTROMETRY; IN-VITRO; IN-VIVO; MS/MS ANALYSIS; ORAL DOSE; PHARMACEUTICAL RESEARCH; POTENTIAL DRUG; PRIORI KNOWLEDGE; SIMULTANEOUS DETECTION; TOXICOKINETICS; WHOLE-BODY;

BIOMOLECULES; METABOLITES; SECONDARY ION MASS SPECTROMETRY;

MASS SPECTROMETERS;

RESERPINE;

ANIMAL; ARTICLE; MALE; METABOLISM; METHODOLOGY; MOLECULAR IMAGING; RAT; SPRAGUE DAWLEY RAT; TIME; WHOLE BODY IMAGING;

ANIMALS; MALE; MOLECULAR IMAGING; RATS; RATS, SPRAGUE-DAWLEY; RESERPINE; TIME FACTORS; WHOLE BODY IMAGING;

EID: 84865448064     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac3015142     Document Type: Article

References (44)

1. Thermo Scientific. Analytical Tools for Metabolism: Biotransformation Reference Guide, Edition 2009.
2. Caldwell, G. W.; Yan, Z. Y.; Tang, W. M.; Dasgupta, M.; Hasting, B. Curr. Topics Med. Chem. 2009, 9, 965
3. Thompson, T. N. Med. Res. Rev. 2001, 21, 412
4. Kassel, D. B. Curr. Opin. Chem. Biol. 2004, 8, 339
5. Singh, S. S. Curr. Drug Metab. 2006, 7, 165
6. Ackermann, B. L.; Berna, M. J.; Murphy, A. T. Curr. Topics Med. Chem. 2002, 2, 53
7. Zhou, L. Z. Separation Science and Technology 2005; Vol. 6, Issue C, p 499-568.
8. Henion, J.; Brewer, E.; Rule, G. Anal. Chem. 1998, 70, 650A
9. Liang, X. R.; Ubhayakar, S.; Liederer, B. M.; Dean, B.; Qin, A. R. R.; Shahidi-Latham, S.; Deng, Y. Z. Bioanalysis 2011, 3, 1923
10. Potchoiba, M. J.; Nocerini, M. R. Drug Metab. Dispos. 2004, 32, 1190
11. Solon, E. G.; Kraus, L. J. Pharmacol. Toxicol. Methods 2001, 46, 73
12. Hahn, E. J. Am. Lab. 1983, 15, 64
13. Khatib-Shahidi, S.; Andersson, M.; Herman, J. L.; Gillespie, T. A.; Caprioli, R. M. Anal. Chem. 2006, 78, 6448
14. Rubakhin, S. S.; Jurchen, J. C.; Monroe, E. B.; Sweedler, J. V. Drug Discovery Today 2005, 10, 823
15. Stoeckli, M.; Staab, D.; Schweitzer, A. Int. J. Mass Spectrom. 2007, 260, 195
16. Reyzer, M. L.; Caprioli, R. M. Curr. Opin. Chem. Biol. 2007, 11, 29
17. Prideaux, B.; Dartois, V.; Staab, D.; Weiner, D. M.; Goh, A.; Via, L. E.; Barry, C. E.; Stoeckli, M. Anal. Chem. 2011, 83, 2112
18. Nilsson, A.; Fehniger, T. E.; Gustavsson, L.; Andersson, M.; Kenne, K.; Marko-Varga, G.; Andren, P. E. Plos One 2010, 5, e11411
19. Castellino, S.; Groseclose, M. R.; Wagner, D. Bioanalysis 2011, 3, 2427
20. Kertesz, V.; Van Berkel, G. J.; Vavrek, M.; Koeplinger, K. A.; Schneider, B. B.; Covey, T. R. Anal. Chem. 2008, 80, 5168
21. Solon, E. G.; Schweitzer, A.; Stoeckli, M.; Prideaux, B. AAPS J. 2010, 12, 11
22. Manier, M. L.; Reyzer, M. L.; Goh, A.; Dartois, V.; Via, L. E.; Barry, C. E., III; Caprioli, R. M. J. Am. Soc. Mass Spectrom. 2011, 22, 1409
23. Reyzer, M. L.; Hsieh, Y.; Ng, K.; Korfmacher, W. A.; Caprioli, R. M. J. Mass Spectrom. 2003, 38, 1081
24. Troendle, F. J.; Reddick, C. D.; Yost, R. A. J. Am. Soc. Mass Spectrom. 1999, 10, 1315
25. Hsieh, Y.; Casale, R.; Fukuda, E.; Chen, J. W.; Knemeyer, I.; Wingate, J.; Morrison, R.; Korfmacher, W. Rapid Commun. Mass Spectrom. 2006, 20, 965
26. Chen, J.; Hsieh, Y.; Knemeyer, I.; Crossman, L.; Korfmacher, W. A. Drug Metab. Lett. 2008, 2, 1
27. Vegvari, A.; Fehniger, T. E.; Gustavsson, L.; Nilsson, A.; Andren, P. E.; Kenne, K.; Nilsson, J.; Laurell, T.; Marko-Varga, G. J. Proteomics 2010, 73, 1270
28. Cornett, D. S.; Frappier, S. L.; Caprioli, R. M. Anal. Chem. 2008, 80, 5648
29. Taban, I. M.; Altelaar, A. F. M.; Van der Burgt, Y. E. M.; McDonnell, L. A.; Heeren, R. M. A.; Fuchser, J.; Baykut, G. J. Am. Soc. Mass Spectrom. 2007, 18, 145
30. Landgraf, R. R.; Conaway, M. C. P.; Garrett, T. J.; Stacpoole, P. W.; Yost, R. A. Anal. Chem. 2009, 81, 8488
31. Rompp, A.; Guenther, S.; Takats, Z.; Spengler, B. Anal. Bioanal. Chem. 2011, 401, 65
32. Perdian, D. C.; Lee, Y. J. Anal. Chem. 2010, 82, 9393
33. Goodman, L. S.; Gilman, A.; Brunton, L. L.; Lazo, J. S.; Parker, K. L. Goodman & Gilman's the pharmacological basis of therapeutics; McGraw-Hill: New York, 2005.
34. Stitzel, R. E. Pharmacol. Rev. 1976, 28, 179
35. Numerof, P.; Gordon, M.; Kelly, J. M. J. Pharmacol. Exp. Ther. 1955, 115, 427
36. Glazko, A. J.; Dill, W. A.; Wolf, L. M.; Kazenko, A. J. Pharmacol. Exp. Ther. 1956, 118, 377
37. Deepak, K. K.; Bhargava, B.; Narang, R.; Paudel, B. H.; Rai, P. K.; Saxena, S. Clin. Auton. Res. 2000, 10, 313
38. Bansal, S. Hypertension 1988, 12, 1
39. Stitzel, R. E.; Wagner, L. A.; Stawarz, R. J. J. Pharmacol. Exp. Ther. 1972, 182, 500
40. Coraggio, M. A.; Khatib-Shahidi, S.; Shin, Y. G.; Hop, C.; Rudewicz, P. J. 57th ASMS Conference on Mass Spectrometry and Allied Topics, May 31-June 4, 2009.
41. Grove, K.; Frappier, S.; Caprioli, R. J. Am. Soc. Mass Spectrom. 2011, 22, 192
42. Yanes, O.; Woo, H.-K.; Northen, T. R.; Oppenheimer, S. R.; Shriver, L.; Apon, J.; Estrada, M. N.; Potchoiba, M. J.; Steenwyk, R.; Manchester, M.; Siuzdak, G. Anal. Chem. 2009, 81, 2969
43. Greving, M. P.; Patti, G. J.; Siuzdak, G. Anal. Chem. 2010, 83, 2
44. Hayden, K.; Vestal, M. Virgin Instruments, Sudbury, MA; 58th ASMS Conference on Mass Spectrometry and Allied Topics, May 23-May 27, 2010.