Essential tactics of tissue preparation and matrix nano-spotting for successful compound imaging mass spectrometry

Journal of Proteomics

Volumn 73, Issue 6, 2010, Pages 1270-1278

  Végvári, Ákos ^a   Fehniger, Thomas E ^b   Gustavsson, Lena ^b   Nilsson, Anna ^c   Andrén, Per E ^c   Kenne, Kerstin ^d   Nilsson, Johan ^a   Laurell, Thomas ^a   Marko Varga, György ^a,b  

^a LUND UNIVERSITY   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

^d ASTRAZENECA R AND D   (Sweden)

Author keywords

MALDI Orbitrap; Matrix spotting; Microdispenser; Rat lung; Tiotropium; Tissue imaging MALDI MS

Indexed keywords

TIOTROPIUM BROMIDE; BRONCHODILATING AGENT; PROTEOME; SCOPOLAMINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; IN VIVO STUDY; LUNG PARENCHYMA; MALE; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION IMAGING MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE PREPARATION; ANIMAL; CRYSTALLIZATION; DEVICES; FLUORESCENCE MICROSCOPY; INHALATION; LUNG; NANOTECHNOLOGY; PATHOLOGY; PROCEDURES; PROTEOMICS; WISTAR RAT;

RATTUS; RODENTIA;

ANIMALS; BRONCHODILATOR AGENTS; CRYSTALLIZATION; INHALATION; LUNG; MALE; MICROSCOPY, FLUORESCENCE; NANOTECHNOLOGY; PROTEOME; PROTEOMICS; RATS; RATS, WISTAR; SCOPOLAMINE DERIVATIVES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 77950518892     PISSN: 18743919     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jprot.2010.02.021     Document Type: Article

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