CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 40, 2009, Pages 17129-17133

  Nitta, Takeshi ^a   Nitta, Sachiko ^a   Yu, Lei ^a   Lipp, Martin ^b   Takahama, Yousuke ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Chemokine; Self tolerance; Thymic epithelial cell; Thymic medulla

Indexed keywords

ANTIGEN; CHEMOKINE RECEPTOR CCR7; INSULIN; TISSUE RESTRICTED ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; CELL DIFFERENTIATION; CELL EXPANSION; CELL MIGRATION; CELL SELECTION; CONTROLLED STUDY; CROSS PRESENTATION; GENE DELETION; GENE EXPRESSION; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; T LYMPHOCYTE; THYMOCYTE; THYMUS;

ANIMALS; ANTIGENS; AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNE TOLERANCE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, CCR7; SIGNAL TRANSDUCTION; THYMUS GLAND;

MUS;

EID: 70350131707     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906956106     Document Type: Article

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