Tyrosol, a main phenol present in extra virgin olive oil, increases lifespan and stress resistance in Caenorhabditis elegans

Mechanisms of Ageing and Development

Volumn 133, Issue 8, 2012, Pages 563-574

  Cañuelo, Ana ^a   Gilbert López, Bienvenida ^a   Pacheco Liñán, Pedro ^a   Martínez Lara, Esther ^a   Siles, Eva ^a   Miranda Vizuete, Antonio ^b  

^a UNIVERSITY OF JAÉN   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

Author keywords

C. elegans; Extra virgin olive oil; Lifespan; Stress resistance; Tyrosol

Indexed keywords

DAF 16 PROTEIN; DAF 2 PROTEIN; HEAT SHOCK PROTEIN; INSULIN; MESSENGER RNA; TRANSCRIPTION FACTOR; TYROSOL; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; HEAT SHOCK RESPONSE; HEAT TOLERANCE; LIFE EXTENSION; LONGEVITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; TEMPERATURE STRESS;

ANIMALS; ANTIOXIDANTS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; HUMANS; LONGEVITY; PHENYLETHYL ALCOHOL; PLANT OILS; RECEPTOR, INSULIN; TRANSCRIPTION FACTORS;

CAENORHABDITIS ELEGANS; METAZOA; NEMATODA;

EID: 84865356857     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2012.07.004     Document Type: Article

References (62)

1. Antebi A. Genetics of aging in Caenorhabditis elegans. PLoS Genetics 2007, 3(9):1565-1571.
2. Barbieri M., Bonafè M., Franceschi C., Paolisso G. Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. American Journal of Physiology-Endocrinology and Metabolism 2003, 285(5):E1064-E1071.
3. Baur J.A., Pearson K.J., Price N.L., Jamieson H.A., Lerin C., Kalra A., Prabhu V.V., Allard J.S., Lopez-Lluch G., Lewis K., Pistell P.J., Poosala S., Becker K.G., Boss O., Gwinn D., Wang M., Ramaswamy S., Fishbein K.W., Spencer R.G., Lakatta E.G., Le Couteur D., Shaw R.J., Navas P., Puigserver P., Ingram D.K., de Cabo R., Sinclair D.A. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006, 444:337-342.
4. Bendini A., Cerretani L., Carrasco-Pancorbo A., Gómez-Caravaca A.M., Segura-Carretero A., Fernández-Gutiérrez A., Lercker G. Phenolic molecules in virgin olive oils: a survey of their sensory properties, health effects, antioxidant activity and analytical methods. An overview of the last decade. Molecules 2007, 12:1679-1719.
5. Bisignano G., Tomaino A., Lo Cascio R., Crisafi G., Uccella N., Saija A. On the in vitro antiomicrobial activity of oleuropein and hydroxytyrosol. Journal of Pharmacy and Pharmacology 1999, 31:971-974.
6. Brenner S. The genetics of Caenorhabditis elegans. Genetics 1974, 77:71-94.
7. Brown M.K., Evans J.L., Luo Y. Beneficial effects of natural antioxidants EGCG and α-lipoic acid on lifespan and age-dependent behavioral declines in Caenorhabditis elegans. Pharmacology Biochemistry and Behavior 2006, 85:620-628.
8. Buckland G., Agudo A., Travier N., Huerta J., Cirera L., Tormo M.J., Navarro C., Chirlaque M., Moreno-Iribas C., Ardanaz E., Barricarte A., Etxeberria J., Marin P., Quirós J., Redondo M.L., Larrañaga N., Amiano P., Dorronsoro M., Arriola L., Basterretxea M., Sanchez M.J., Molina E., González C.A. Adherence to the Mediterranean diet reduces mortality in the Spanish cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Spain). British Journal of Nutrition 2011, 106:1581-1591.
9. Carrasco-Pancorbo A., Cerretani L., Bendini A., Segura-Carretero A., Gallina-Toschi T., Fernandez-Gutiérrez A. Analytical determination of polyphenols in olive oils. Journal of Separation Science 2005, 28:837-858.
10. Caruso D., Berra B., Giavarini F., Cortesi N., Fedeli E., Galli G. Effect of virgin olive oil phenolic compounds on in vitro oxidation of human low density lipoproteins. Nutrition Metabolism and Cardiovascular Diseases 1999, 9(3):102-107.
11. Correa J.A., López-Villodres J.A., Asensi R., Espartero J.L., Rodríguez-Gutiérez G., De La Cruz J.P. Virgin olive oil polyphenol hydroxytyrosol acetate inhibits in vitro platelet aggregation in human whole blood: comparison with hydroxytyrosol and acetylsalicylic acid. British Journal of Nutrition 2009, 101(8):1157-1164.
12. Frankel E.N. Nutritional and biological properties of extra virgin olive oil. Journal of Agricultural and Food Chemistry 2011, 59(3):785-792.
13. García-Villalba R., Carrasco-Pancorbo A., Oliveras-Ferraros C., Vázquez-Martín A., Menéndez J.A., Segura-Carretero A., Fernández-Gutiérrez A. Characterization and quantification of phenolic compounds of extra-virgin olive oils with anticancer properties by a rapid and resolutive LC-ESI-TOF MS method. Journal of Pharmaceutical and Biomedical Analysis 2009, 51(2):416-429.
14. Garigan D., Hsu A.L., Fraser A.G., Kamath R.S., Ahringer J., Kenyon C. Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics 2002, 161(3):1101-1112.
15. Gems D., Riddle D.L. Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans. Genetics 2000, 154:1597-1610.
16. Gerber M. Biofactors in the Mediterranean Diet. Clinical Chemistry and Laboratory Medicine 2003, 41:999-1004.
17. Giese K.C., Vierling E. Changes in oligomerization are essential for the chaperone activity of a small heat shock protein in vivo and in vitro. Journal of Biological Chemistry 2002, 277(48):46310-46318.
18. Golden T.R., Melov S. Microarray analysis of gene expression with age in individual nematodes. Aging Cell 2004, 3:111-124.
19. Greer E.L., Brunet A. Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell 2009, 8(2):113-127.
20. Guarente L., Kenyon C. Genetic pathways that regulate ageing in model organisms. Nature 2000, 408(6809):255-262.
21. Guarente L. Calorie restriction and SIR2 genes - towards a mechanism. Mechanisms of Ageing and Development 2005, 126:923-928.
22. Henderson S.T., Johnson T.E. Daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Current Biology 2001, 11:1975-1980.
23. Herndon L.A., Schmeissner P.J., Dudaronek J.M., Brown P.A., Listner K.M., Sakano Y., Paupard M.C., Hall D.H., Driscoll M. Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 2002, 419(6909):808-814.
24. Hsin H., Kenyon C. Signals from the reproductive system regulate the lifespan of C. elegans. Nature 1999, 399(6734):362-366.
25. Howitz K.T., Bitterman K.J., Cohen H.Y., Lamming D.W., Lavu S., Wood J.G., Zipkin R.E., Chung P., Kisielewski A., Zhang L.L., Scherer B., Sinclair D.A. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 2003, 425:191-196.
26. Hsu A., Murphy C.T., Kenyon C. Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 2003, 300:1142-1145.
27. Huang C., Xiong C., Kornfeld K. Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America 2004, 101(21):8049-8084.
28. Ishii N., Fujii M., Hartman P.S., Tsuda M., Yasuda K., Senoo-Matsuda N., Yanase S., Ayusawa D., Suzuki K. A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes. Nature 1998, 394:694-697.
29. Jacomelli M., Pitozzi V., Zaid M., Larrosa M., Tonini G., Martini A., Urbani S., Taticchi A., Servili M., Dolara P., Giovannelli L. Dietary extra-virgin olive oil rich in phenolic antioxidants and the aging process: long-term effects in the rat. Journal of Nutritional Biochemistry 2010, 21(4):290-296.
30. Johnson T.E., Henderson S., Murakami S., de Castro E., de Castro S.H., Cypser J., Rikke B., Tedesco P., Link C. Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease. Journal of Inherited Metabolic Disease 2002, 25(3):197-206.
31. Joseph J.A., Shukitt-Hale B., Casadesus G. Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds. American Journal of Clinical Nutrition 2005, 81:313S-316S.
32. Kampkötter A., Nkwonkam C.G., Zurawski R.F., Timpel C., Chovolou Y., Wätjen W., Kahl R. Investigations of protective effects of the flavonoids quercetin and rutin on stress resistance in the model organism Caenorhabditis elegans. Toxicology 2007, 234:113-123.
33. Kampkötter A., Timpel C., Zurawski R.F., Ruhl, Chovolou S., Proksch Y., Wätjen P.W. Increase of stress resistance and lifespan of Caenorhabditis elegans by quercetin. Comparative Biochemistry and Physiology B: Biochemistry and Molecular Biology 2008, 149:314-323.
34. Kenyon C., Chang J., Gensch E., Rudner A., Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 1993, 366:461-464.
35. Kimura K.D., Tissenbaum H.A., Liu Y., Ruvkun G. Daf-2, an insulin receptor-like gene that regulates longevity and diapause in caenorhabditis elegans. Science 1997, 277:942-946.
36. Klass M.R. Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span. Mechanisms of Ageing and Development 1977, 6:413-429.
37. Lagiou P., Trichopoulos D., Sandin S., Lagiou A., Mucci L., Wolk A., Weiderpass E., Adami H.O. Mediterranean dietary pattern and mortality among young women: a cohort study in Sweden. British Journal of Nutrition 2006, 96:384-392.
38. Lee S.S., Kennedy S., Tolonen A.C., Ruvkun G. DAF-16 target genes that control C. elegans life-span and metabolism. Science 2003, 300:644.
39. Lund J., Tedesco P., Duke K., Wang J., Kim S.K., Johnson T.E. Transcriptional profile of aging in C. elegans. Current Biology 2002, 2:1566-1573.
40. Manach C., Williamson G., Morand C., Scalbert A., Rémésy C. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. American Journal of Clinical Nutrition 2005, 81:230S-242S.
41. Muñoz M.J. Longevity and heat stress regulation in Caenorhabditis elegans. Mechanisms of Ageing and Development 2003, 124(1):43-48.
42. Murphy C.T., McCarroll S.A., Bargmann C.I., Fraser A., Kamath R.S., Ahringer J., Li H., Kenyon C. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 2003, 424:277-283.
43. Oh S.K., Mukhopadhyay A., Svrzikapa N., Jiang F., Davis R.J., Tissenbaum H.A. JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. Proceedings of the National Academy of Sciences of the United States of America 2006, 102(12):4494-4499.
44. Putics A., Végh E.M., Csermely P., Soti C. Resveratrol induces the heat-shock response and protects human cells from severe heat stress. Antioxidants and Redox Signalling 2008, 10(1):65-75.
45. Rattan S.I., Sejersen H., Fernandes R.A., Luo W. Stress-mediated hormetic modulation of aging, wound healing, and angiogenesis in human cells. Annals of the New York Academy of Sciences 2007, 1119:112-121.
46. Saul N., Pietsch K., Menzel R., Steinberg C.E.W. Quercetin-mediated longevity in Caenorhabditis elegans: is DAF-16 involved?. Mechanisms of Ageing and Development 2008, 129:611-613.
47. Saul N., Pietsch K., Menzel R., Stürzenbaum S.R., Steinberg C.E.W. Catechin induced longevity in C. elegans. From key regulator genes to disposable soma. Mechanisms of Ageing and Development 2009, 130:477-486.
48. Schaffitzel E., Hertweck M. Recent aging research in Caenorhabditis elegans. Experimental Gerontology 2006, 41(6):557-563.
49. Stoclet J.C., Chataigneau T., Ndiaye M., Oak M.O., El B.J., Chataigneau M., Schini-Kerth V.B. Vascular protection by dietary polyphenols. European Journal of Pharmacology 2004, 500:299-313.
50. Senoo-Matsuda N., Yasuda K., Tsuda M., Ohkubo T., Yoshimura S., Nakazawa H., Hartman P.S., Ishii N. A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans. Journal of Biological Chemistry 2001, 276:41553-41558.
51. Tatar M., Khazaeli A.A., Curtsinger J.W. Chaperoning extended life. Nature 1997, 390(6655):30.
52. + dependent histone deacetylases (sirtuins) in ageing. Current Drug Targets 2006, 7(11):1553-1560.
53. Trichopoulou A., Orfanos P., Norat T., Bueno-de-Mesquita B., Ocké M.C., Peeters P.H., van der Schouw Y.T., Boeing H., Hoffmann K., Boffetta P., Nagel G., Masala G., Krogh V., Panico S., Tumino R., Vineis P., Bamia C., Naska A., Benetou V., Ferrari P., Slimani N., Pera G., Martinez-Garcia C., Navarro C., Rodriguez-Barranco M., Dorronsoro M., Spencer E.A., Key T.J., Bingham S., Khaw K.T., Kesse E., Clavel-Chapelon F., Boutron-Ruault M.C., Berglund G., Wirfalt E., Hallmans G., Johansson I., Tjonneland A., Olsen A., Overvad K., Hundborg H.H., Riboli E., Trichopoulos D. Modified Mediterranean diet and survival, EPIC elderly prospective cohort study. BMJ 2005, 330:991-997.
54. Tuck K.L., Hayball P.J. Major phenolic compounds in olive oil: metabolism and health effects. Journal of Nutritional Biochemistry 2002, 13:636-644.
55. Valenzano D.R., Terzibasi E., Genade T., Cattaneo A., Domenici L., Cellerino A. Resveratrol prolongs lifespan and retards the onset of agerelated markers in a short-lived vertebrate. Current Biology 2006, 16:296-300.
56. Verbeke P., Fonager J., Clark B.F., Rattan S.I. Heat shock response and ageing: mechanisms and applications. Cell Biology International 2001, 25(9):845-857.
57. Visioli F., Galli C. Olive oil phenols and their potential effects on human health. Journal of Agricultural and Food Chemistry 1998, 46:4292-4296.
58. Viswanathan M., Kim S.K., Berdichevsky A., Guarente L. A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span. Developmental Cell 2005, 9:605-615.
59. Walker G., Houthoofd K., Vanfleteren J.R., Gems D. Dietary restriction in C. elegans. From rate-of-living effects to nutrient sensing pathways. Mechanisms of Ageing and Development 2005, 126:929-937.
60. Wilson M.A., Shukitt-Hale B., Kalt W., Ingram D.K., Joseph J.A., Wolkow C.A. Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans. Aging Cell 2006, 5:59-68.
61. Wood J.G., Rogina B., Lavu S., Howitz K., Helfand S.L., Tatar M., Sinclair D. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 2004, 430:686-689.
62. Wu Z., Smith J.V., Paramasivam V., Butko P., Khan I., Cypser J.R., Luo Y. Ginkgo biloba extract EGb 761 increases stress resistance and extends life span of Caenorhabditis elegans. Cellular and Molecular Biology 2002, 48(6):725-731.