메뉴 건너뛰기




Volumn 2010, Issue , 2010, Pages

Differential toxicity of DNA adducts of mitomycin C

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHECKPOINT KINASE 1; DNA; MITOMYCIN C; PROTEIN P53;

EID: 84865355889     PISSN: 20900201     EISSN: 2090021X     Source Type: Journal    
DOI: 10.4061/2010/698960     Document Type: Review
Times cited : (45)

References (34)
  • 4
    • 0026756615 scopus 로고
    • Novel interstrand cross-links induced by the antitumor antibiotic carzinophilin/azinomycin B
    • 2-s2.0-0026756615
    • Armstrong R. W., Salvati M. E., Nguyen M., Novel interstrand cross-links induced by the antitumor antibiotic carzinophilin/azinomycin B. Journal of the American Chemical Society 1992 114 8 3144 3145 2-s2.0-0026756615
    • (1992) Journal of the American Chemical Society , vol.114 , Issue.8 , pp. 3144-3145
    • Armstrong, R.W.1    Salvati, M.E.2    Nguyen, M.3
  • 5
    • 0023123806 scopus 로고
    • Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA
    • Tomasz M., Lipman R., Chowdary D., Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA. Science 1987 235 4793 1204 1208 2-s2.0-0023123806 (Pubitemid 17034007)
    • (1987) Science , vol.235 , Issue.4793 , pp. 1204-1208
    • Tomasz, M.1    Lipman, R.2    Chowdary, D.3
  • 6
    • 0029360580 scopus 로고
    • Mitomycin C: Small, fast and deadly (but very selective)
    • 2-s2.0-0029360580
    • Tomasz M., Mitomycin C: small, fast and deadly (but very selective). Chemistry and Biology 1995 2 9 575 579 2-s2.0-0029360580
    • (1995) Chemistry and Biology , vol.2 , Issue.9 , pp. 575-579
    • Tomasz, M.1
  • 7
    • 0019835111 scopus 로고
    • Reductive metabolism and alkylating activity of mitomycin C induced by rat liver microsomes
    • Tomasz M., Lipman R., Reductive metabolism and alkylating activity of mitomycin C induced by rat liver microsomes. Biochemistry 1981 20 17 5056 5061 2-s2.0-0019835111 (Pubitemid 12195997)
    • (1981) Biochemistry , vol.20 , Issue.17 , pp. 5056-5061
    • Tomasz, M.1    Lipman, R.2
  • 8
    • 0029566296 scopus 로고
    • Re-evaluation of the molecular pharmacology of Mitomycin C
    • DOI 10.1016/0959-8049(95)00364-9
    • Cummings J., Spanswick V. J., Smyth J. F., Re-evaluation of the molecular pharmacology of Mitomycin C. European Journal of Cancer Part A 1995 31 12 1928 1933 2-s2.0-0029566296 10.1016/0959-8049(95)00364-9 (Pubitemid 26023082)
    • (1995) European Journal of Cancer Part A: General Topics , vol.31 , Issue.12 , pp. 1928-1933
    • Cummings, J.1    Spanswick, V.J.2    Smyth, J.F.3
  • 9
    • 0032242916 scopus 로고    scopus 로고
    • Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C
    • Palom Y., Belcourt M. F., Kumar G. S., Arai H., Kasai M., Sartorelli A. C., Rockwell S., Tomasz M., Formation of a major DNA adduct of the mitomycin metabolite 2,7-diaminomitosene in EMT6 mouse mammary tumor cells treated with mitomycin C. Oncology Research 1998 10 10 509 521 2-s2.0-0032242916 (Pubitemid 128736340)
    • (1998) Oncology Research , vol.10 , Issue.10 , pp. 509-521
    • Palom, Y.1    Belcourt, M.F.2    Suresh Kumar, G.3    Arai, H.4    Kasai, M.5    Sartorelli, A.C.6    Rockwell, S.7    Tomasz, M.8
  • 10
    • 0000797824 scopus 로고    scopus 로고
    • Structure of adduct X, the last unknown of the six major DNA adducts of mitomycin C formed in EMT6 mouse mammary tumor cells
    • DOI 10.1021/tx000024j
    • Palom Y., Belcourt M. F., Musser S. M., Sartorelli A. C., Rockwell S., Tomasz M., Structure of adduct X, the last unknown of the six major DNA adducts of mitomycin C formed in EMT6 mouse mammary tumor cells. Chemical Research in Toxicology 2000 13 6 479 488 2-s2.0-0000797824 10.1021/tx000024j (Pubitemid 30416343)
    • (2000) Chemical Research in Toxicology , vol.13 , Issue.6 , pp. 479-488
    • Palom, Y.1    Belcourt, M.F.2    Musser, S.M.3    Sartorelli, A.C.4    Rockwell, S.5    Tomasz, M.6
  • 11
    • 0001229584 scopus 로고    scopus 로고
    • 2,7-Diaminomitosene, a monofunctional mitomycin C derivative, alkylates DNA in the major groove. Structure and base-sequence specificity of the DNA adduct and mechanism of the alkylation
    • DOI 10.1021/ja9607401
    • Kumar G. S., Musser S. M., Cummings J., Tomasz M., 2,7-Diaminomitosene, a monofunctional mitomycin C derivative, alkylates DNA in the major groove. Structure and base-sequence specificity of the DNA adduct and mechanism of the alkylation. Journal of the American Chemical Society 1996 118 39 9209 9217 2-s2.0-0001229584 10.1021/ja9607401 (Pubitemid 26355113)
    • (1996) Journal of the American Chemical Society , vol.118 , Issue.39 , pp. 9209-9217
    • Kumar, G.S.1    Musser, S.M.2    Cummings, J.3    Tomasz, M.4
  • 12
    • 0035877170 scopus 로고    scopus 로고
    • Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: Cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol
    • DOI 10.1016/S0006-2952(01)00609-8, PII S0006295201006098
    • Palom Y., Belcourt M. F., Tang L.-Q., Mehta S. S., Sartorelli A. C., Pritsos C. A., Pritsos K. L., Rockwell S., Tomasz M., Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol. Biochemical Pharmacology 2001 61 12 1517 1529 2-s2.0-0035877170 10.1016/S0006-2952(01)00609-8 (Pubitemid 32476906)
    • (2001) Biochemical Pharmacology , vol.61 , Issue.12 , pp. 1517-1529
    • Palom, Y.1    Belcourt, M.F.2    Tang, L.-Q.3    Mehta, S.S.4    Sartorelli, A.C.5    Pritsos, C.A.6    Pritsos, K.L.7    Rockwell, S.8    Tomasz, M.9
  • 14
    • 13844269362 scopus 로고    scopus 로고
    • DNA adduct of the mitomycin C metabolite 2,7-diaminomitosene is a nontoxic and nonmutagenic DNA lesion in vitro and in vivo
    • DOI 10.1021/tx049813h
    • Utzat C. D., Clement C. C., Ramos L. A., Das A., Tomasz M., Basu A. K., DNA adduct of the mitomycin C metabolite 2,7-diaminomitosene is a nontoxic and nonmutagenic DNA lesion in vitro and in vivo. Chemical Research in Toxicology 2005 18 2 213 223 2-s2.0-13844269362 10.1021/tx049813h (Pubitemid 40256239)
    • (2005) Chemical Research in Toxicology , vol.18 , Issue.2 , pp. 213-223
    • Utzat, C.D.1    Clement, C.C.2    Ramos, L.A.3    Das, A.4    Tomasz, M.5    Basu, A.K.6
  • 15
    • 0015012750 scopus 로고
    • Mitomycin derivatives. 2. Derivatives of decarbamoylmitosane and decarbamoylmitosene
    • 2-s2.0-0015012750
    • Kinoshita S., Uzu K., Nakano K., Takahashi T., Mitomycin derivatives. 2. Derivatives of decarbamoylmitosane and decarbamoylmitosene. Journal of Medicinal Chemistry 1971 14 2 109 112 2-s2.0-0015012750
    • (1971) Journal of Medicinal Chemistry , vol.14 , Issue.2 , pp. 109-112
    • Kinoshita, S.1    Uzu, K.2    Nakano, K.3    Takahashi, T.4
  • 16
    • 0018640307 scopus 로고
    • DNA crosslinking, sister-chromatid exchange and specific mutations
    • Carrano A. V., Thompson L. H., Stetka D. G., DNA crosslinking, sister-chromatid exchange and specific mutations. Mutation Research 1979 63 1 175 188 2-s2.0-0018640307 (Pubitemid 10199112)
    • (1979) Mutation Research , vol.63 , Issue.1 , pp. 175-188
    • Carrano, A.V.1    Thompson, L.H.2    Stetka, D.G.3
  • 17
    • 0023772270 scopus 로고
    • Isolation and characterization of a major adduct between mitomycin C and DNA
    • 2-s2.0-0023772270
    • Tomasz M., Lipman R., McGuinness B. F., Nakanishi K., Isolation and characterization of a major adduct between mitomycin C and DNA. Journal of the American Chemical Society 1988 110 17 5892 5896 2-s2.0-0023772270
    • (1988) Journal of the American Chemical Society , vol.110 , Issue.17 , pp. 5892-5896
    • Tomasz, M.1    Lipman, R.2    McGuinness, B.F.3    Nakanishi, K.4
  • 18
    • 0025352024 scopus 로고
    • Decreased NADPH:cytochrome P-450 reductase activity and impaired drug activation in a mammalian cell line resistant to mitomycin C under aerobic but not hypoxic conditions
    • Hoban P. R., Walton M. I., Robson C. N., Godden J., Stratford I. J., Workman P., Harris A. L., Hickson I. D., Decreased NADPH: cytochrome P-450 reductase activity and impaired drug activation in a mammalian cell line resistant to mitomycin C under aerobic but not hypoxic conditions. Cancer Research 1990 50 15 4692 4697 2-s2.0-0025352024 (Pubitemid 20230414)
    • (1990) Cancer Research , vol.50 , Issue.15 , pp. 4692-4697
    • Hoban, P.R.1    Walton, M.I.2    Robson, C.N.3    Godden, J.4    Stratford, I.J.5    Workman, P.6    Harris, A.L.7    Hickson, I.D.8
  • 19
    • 58149322569 scopus 로고
    • Cytotoxic potential of monoalkylation products between mitomycins and DNA: Studies of decarbamoyl mitomycin C in wild-type and repair-deficient cell lines
    • 2-s2.0-0029086720
    • Rockwell S., Kim S. Y., Cytotoxic potential of monoalkylation products between mitomycins and DNA: studies of decarbamoyl mitomycin C in wild-type and repair-deficient cell lines. Oncology Research 1995 7 1 39 47 2-s2.0-0029086720
    • (1995) Oncology Research , vol.7 , Issue.1 , pp. 39-47
    • Rockwell, S.1    Kim, S.Y.2
  • 20
    • 0036852787 scopus 로고    scopus 로고
    • Relative toxicities of DNA cross-links and monoadducts: New insights from studies of decarbamoyl mitomycin C and mitomycin C
    • DOI 10.1021/tx020044g
    • Palom Y., Kumar G. S., Tang L.-Q., Paz M. M., Musser S. M., Rockwell S., Tomasz M., Relative toxicities of DNA cross-links and monoadducts: new insights from studies of decarbamoyl mitomycin C and mitomycin C. Chemical Research in Toxicology 2002 15 11 1398 1406 2-s2.0-0036852787 10.1021/tx020044g (Pubitemid 35364901)
    • (2002) Chemical Research in Toxicology , vol.15 , Issue.11 , pp. 1398-1406
    • Palom, Y.1    Suresh Kumar, G.2    Tang, L.-Q.3    Paz, M.M.4    Musser, S.M.5    Rockwell, S.6    Tomasz, M.7
  • 21
    • 0031884662 scopus 로고    scopus 로고
    • The major mitomycin C-DNA monoadduct is cytotoxic but not mutagenic in Escherichia coli
    • DOI 10.1021/tx970163+
    • Ramos L. A., Lipman R., Tomasz M., Basu A. K., The major mitomycin C-DNA monoadduct is cytotoxic but not mutagenic in Escherichia coli. Chemical Research in Toxicology 1998 11 1 64 69 2-s2.0-0031884662 10.1021/tx970163+ (Pubitemid 28065274)
    • (1998) Chemical Research in Toxicology , vol.11 , Issue.1 , pp. 64-69
    • Ramos, L.A.1    Lipman, R.2    Tomasz, M.3    Basu, A.K.4
  • 22
    • 0027271948 scopus 로고
    • Effect of site-specifically located mitomycin C-DNA monoadducts on in vitro DNA synthesis by DNA polymerases
    • DOI 10.1021/bi00069a004
    • Basu A. K., Hanrahan C. J., Malia S. A., Kumar S., Bizanek R., Tomasz M., Effect of site-specifically located mitomycin C-DNA monoadducts on in vitro DNA synthesis by DNA polymerases. Biochemistry 1993 32 18 4708 4718 2-s2.0-0027271948 10.1021/bi00069a004 (Pubitemid 23162025)
    • (1993) Biochemistry , vol.32 , Issue.18 , pp. 4708-4718
    • Basu, A.K.1    Hanrahan, C.J.2    Malia, S.A.3    Kumar, S.4    Bizanek, R.5    Tomasz, M.6
  • 23
    • 58149092958 scopus 로고    scopus 로고
    • Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/electrospray tandem mass spectrometry
    • 2-s2.0-58149092958 10.1021/tx8002615
    • Paz M. M., Ladwa S., Champeil E., Liu Y., Rockwell S., Boamah E. K., Bargonetti J., Callahan J., Roach J., Tomasz M., Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/electrospray tandem mass spectrometry. Chemical Research in Toxicology 2008 21 12 2370 2378 2-s2.0-58149092958 10.1021/tx8002615
    • (2008) Chemical Research in Toxicology , vol.21 , Issue.12 , pp. 2370-2378
    • Paz, M.M.1    Ladwa, S.2    Champeil, E.3    Liu, Y.4    Rockwell, S.5    Boamah, E.K.6    Bargonetti, J.7    Callahan, J.8    Roach, J.9    Tomasz, M.10
  • 24
    • 34547586075 scopus 로고    scopus 로고
    • Mitomycin-DNA adducts induce p53-dependent and p5-independent cell death pathways
    • DOI 10.1021/cb700060t
    • Boamah E. K., White D. E., Talbott K. E., Arva N. C., Berman D., Tomasz M., Bargonetti J., Mitomycin-DNA adducts induce p53-dependent and p5-independent cell death pathways. ACS Chemical Biology 2007 2 6 399 407 2-s2.0-34547586075 10.1021/cb700060t (Pubitemid 350010544)
    • (2007) ACS Chemical Biology , vol.2 , Issue.6 , pp. 399-407
    • Boamah, E.K.1    White, D.E.2    Talbott, K.E.3    Arva, N.C.4    Berman, D.5    Tomasz, M.6    Bargonetti, J.7
  • 25
    • 40449120350 scopus 로고    scopus 로고
    • An oncogene-induced DNA damage model for cancer development
    • DOI 10.1126/science.1140735
    • Halazonetis T. D., Gorgoulis V. G., Bartek J., An oncogene-induced DNA damage model for cancer development. Science 2008 319 5868 1352 1355 2-s2.0-40449120350 10.1126/science.1140735 (Pubitemid 351354863)
    • (2008) Science , vol.319 , Issue.5868 , pp. 1352-1355
    • Halazonetis, T.D.1    Gorgoulis, V.G.2    Bartek, J.3
  • 26
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the light: The growing complexity of p53
    • 2-s2.0-65349103899 10.1016/j.cell.2009.04.037
    • Vousden K. H., Prives C., Blinded by the light: the growing complexity of p53. Cell 2009 137 3 413 431 2-s2.0-65349103899 10.1016/j.cell.2009.04.037
    • (2009) Cell , vol.137 , Issue.3 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 27
    • 1542751745 scopus 로고    scopus 로고
    • Targeting DNA checkpoint kinases in cancer therapy
    • 2-s2.0-1542751745
    • Zhou B. B., Anderson H. J., Roberge M., Targeting DNA checkpoint kinases in cancer therapy. Cancer Biology & Therapy 2003 2 4 S16 S22 2-s2.0-1542751745
    • (2003) Cancer Biology & Therapy , vol.2 , Issue.4
    • Zhou, B.B.1    Anderson, H.J.2    Roberge, M.3
  • 28
    • 69749095427 scopus 로고    scopus 로고
    • Checkpoint signaling from a single DNA interstrand crosslink
    • 2-s2.0-69749095427 10.1016/j.molcel.2009.08.014
    • Ben-Yehoyada M., Wang L. C., Kozekov I. D., Rizzo C. J., Gottesman M. E., Gautier J., Checkpoint signaling from a single DNA interstrand crosslink. Molecular Cell 2009 35 5 704 715 2-s2.0-69749095427 10.1016/j.molcel.2009.08.014
    • (2009) Molecular Cell , vol.35 , Issue.5 , pp. 704-715
    • Ben-Yehoyada, M.1    Wang, L.C.2    Kozekov, I.D.3    Rizzo, C.J.4    Gottesman, M.E.5    Gautier, J.6
  • 29
    • 33846821915 scopus 로고    scopus 로고
    • p53-Deficient Cells Rely on ATM- and ATR-Mediated Checkpoint Signaling through the p38MAPK/MK2 Pathway for Survival after DNA Damage
    • DOI 10.1016/j.ccr.2006.11.024, PII S1535610806003825
    • Reinhardt H. C., Aslanian A. S., Lees J. A., Yaffe M. B., p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage. Cancer Cell 2007 11 2 175 189 2-s2.0-33846821915 10.1016/j.ccr.2006.11.024 (Pubitemid 46209849)
    • (2007) Cancer Cell , vol.11 , Issue.2 , pp. 175-189
    • Reinhardt, H.C.1    Aslanian, A.S.2    Lees, J.A.3    Yaffe, M.B.4
  • 31
    • 24044476837 scopus 로고    scopus 로고
    • Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway
    • DOI 10.1016/j.molcel.2005.07.019, PII S1097276505015078
    • Zhang Y.-W., Otterness D. M., Chiang G. G., Xie W., Liu Y.-C., Mercurio F., Abraham R. T., Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. Molecular Cell 2005 19 5 607 618 2-s2.0-24044476837 10.1016/j.molcel.2005.07.019 (Pubitemid 41219437)
    • (2005) Molecular Cell , vol.19 , Issue.5 , pp. 607-618
    • Zhang, Y.-W.1    Otterness, D.M.2    Chiang, G.G.3    Xie, W.4    Liu, Y.-C.5    Mercurio, F.6    Abraham, R.T.7
  • 33
    • 77955266264 scopus 로고    scopus 로고
    • DNA adducts of decarbamoyl mitomycin C efficiently kill cells with compromised p53 resulting from proteasome-mediated degradation of Chk1
    • Boamah E. K., Brekman A., Tomasz M., DNA adducts of decarbamoyl mitomycin C efficiently kill cells with compromised p53 resulting from proteasome-mediated degradation of Chk1. Chemical Research in Toxicology 2010 23 7 1151 1162
    • (2010) Chemical Research in Toxicology , vol.23 , Issue.7 , pp. 1151-1162
    • Boamah, E.K.1    Brekman, A.2    Tomasz, M.3
  • 34
    • 69749106825 scopus 로고    scopus 로고
    • Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication
    • 2-s2.0-69749106825 10.1016/j.molcel.2009.06.034
    • Shen X., Do H., Li Y., Chung W.-H., Tomasz M., de Winter J. P., Xia B., Elledge S. J., Wang W., Li L., Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication. Molecular Cell 2009 35 5 716 723 2-s2.0-69749106825 10.1016/j.molcel.2009.06.034
    • (2009) Molecular Cell , vol.35 , Issue.5 , pp. 716-723
    • Shen, X.1    Do, H.2    Li, Y.3    Chung, W.-H.4    Tomasz, M.5    De Winter, J.P.6    Xia, B.7    Elledge, S.J.8    Wang, W.9    Li, L.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.