Mitomycin-DNA adducts induce p53-dependent and p5-independent cell death pathways

ACS Chemical Biology

Volumn 2, Issue 6, 2007, Pages 399-407

  Boamah, Ernest K ^a   White, David E ^a,c   Talbott, Kathryn E ^a   Arva, Nicoleta C ^a   Berman, Daniel ^a   Tomasz, Maria ^b   Bargonetti, Jill ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

^c WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; CHECKPOINT KINASE 1; CYSTEINE PROTEINASE; DECARBAMOYLMITOMYCIN C; DOUBLE STRANDED DNA; MITOMYCIN C; MITOMYCIN C DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE; PROTEIN P53; PROTEIN P73; UNCLASSIFIED DRUG; 10-DECARBAMOYLMITOMYCIN C; MITOMYCIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL STRAIN K 562; COLON CANCER; CONTROLLED STUDY; DNA ADDUCT; DNA STRAND BREAKAGE; DRUG CYTOTOXICITY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME DEGRADATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; COMPARATIVE STUDY; DRUG EFFECT; GENETICS; MOUSE; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; CELL DEATH; CELL LINE, TUMOR; DNA ADDUCTS; HUMANS; MICE; MITOMYCINS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34547586075     PISSN: 15548929     EISSN: None     Source Type: Journal    
DOI: 10.1021/cb700060t     Document Type: Article

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