-
1
-
-
23944475174
-
Changing cell fate by nuclear reprogramming
-
Simonsson, S. & J.B. Gurdon 2005. Changing cell fate by nuclear reprogramming. Cell Cycle 4: 513-515.
-
(2005)
Cell Cycle
, vol.4
, pp. 513-515
-
-
Simonsson, S.1
Gurdon, J.B.2
-
2
-
-
0024273487
-
Genomic multipotentiality of differentiated somatic cells
-
DiBerardino, M.A. 1988. Genomic multipotentiality of differentiated somatic cells. Cell Differ. Dev. 25(Suppl): 129-136.
-
(1988)
Cell Differ. Dev
, vol.25
, Issue.SUPPL.
, pp. 129-136
-
-
DiBerardino, M.A.1
-
3
-
-
0035499457
-
Reprogramming of genome function through epigenetic inheritance
-
Surani, M.A. 2001. Reprogramming of genome function through epigenetic inheritance. Nature 414: 122-128.
-
(2001)
Nature
, vol.414
, pp. 122-128
-
-
Surani, M.A.1
-
4
-
-
77953466536
-
Nuclear reprogramming to a pluripotent state by three approaches
-
Yamanaka, S. & H.M. Blau 2010. Nuclear reprogramming to a pluripotent state by three approaches. Nature 465: 704-712.
-
(2010)
Nature
, vol.465
, pp. 704-712
-
-
Yamanaka, S.1
Blau, H.M.2
-
5
-
-
0000331391
-
Adult frogs derived from the nuclei of single somatic cells
-
Gurdon, J.B. 1962. Adult frogs derived from the nuclei of single somatic cells. Dev. Biol. 4: 256-273.
-
(1962)
Dev. Biol
, vol.4
, pp. 256-273
-
-
Gurdon, J.B.1
-
6
-
-
0031044215
-
Viable offspring derived from fetal and adult mammalian cells
-
Wilmut, I. et al 1997. Viable offspring derived from fetal and adult mammalian cells. Nature 385: 810-813.
-
(1997)
Nature
, vol.385
, pp. 810-813
-
-
Wilmut, I.1
-
7
-
-
0037186519
-
Monoclonal mice generated by nuclear transfer from mature B and T donor cells
-
Hochedlinger, K. & R. Jaenisch 2002. Monoclonal mice generated by nuclear transfer from mature B and T donor cells. Nature 415: 1035-1038.
-
(2002)
Nature
, vol.415
, pp. 1035-1038
-
-
Hochedlinger, K.1
Jaenisch, R.2
-
8
-
-
20544477745
-
Generation of cloned mice by direct nuclear transfer from natural killer T cells
-
Inoue, K. et al 2005. Generation of cloned mice by direct nuclear transfer from natural killer T cells. Curr. Biol. 15: 1114-1118.
-
(2005)
Curr. Biol
, vol.15
, pp. 1114-1118
-
-
Inoue, K.1
-
9
-
-
0014692015
-
Suppression of malignancy by cell fusion
-
Harris, H. et al 1969. Suppression of malignancy by cell fusion. Nature 223: 363-368.
-
(1969)
Nature
, vol.223
, pp. 363-368
-
-
Harris, H.1
-
10
-
-
0022367980
-
Plasticity of the differentiated state
-
Blau, H.M. et al 1985. Plasticity of the differentiated state. Science 230: 758-766.
-
(1985)
Science
, vol.230
, pp. 758-766
-
-
Blau, H.M.1
-
11
-
-
0021734785
-
Reprogramming cell differentiation in the absence of DNA synthesis
-
Chiu, C.P. & H.M. Blau 1984. Reprogramming cell differentiation in the absence of DNA synthesis. Cell 37: 879-887.
-
(1984)
Cell
, vol.37
, pp. 879-887
-
-
Chiu, C.P.1
Blau, H.M.2
-
12
-
-
0035797898
-
Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells
-
Tada, M. et al 2001. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr. Biol. 11: 1553-1558.
-
(2001)
Curr. Biol
, vol.11
, pp. 1553-1558
-
-
Tada, M.1
-
13
-
-
52949106486
-
Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2
-
Pereira, C.F. et al 2008. Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2. PLoS Genet. 4: e1000170.
-
(2008)
PLoS Genet
, vol.4
-
-
Pereira, C.F.1
-
14
-
-
23944457397
-
Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells
-
Cowan, C.A. et al 2005. Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 309: 1369-1373.
-
(2005)
Science
, vol.309
, pp. 1369-1373
-
-
Cowan, C.A.1
-
15
-
-
8644231848
-
Nuclei of embryonic stem cells reprogram somatic cells
-
Do, J.T. & H.R. Scholer 2004. Nuclei of embryonic stem cells reprogram somatic cells. Stem Cells 22: 941-949.
-
(2004)
Stem Cells
, vol.22
, pp. 941-949
-
-
Do, J.T.1
Scholer, H.R.2
-
16
-
-
0038038205
-
Nuclei of adult mammalian somatic cells are directly reprogrammed to oct-4 stem cell gene expression by amphibian oocytes
-
Byrne, J.A. et al 2003. Nuclei of adult mammalian somatic cells are directly reprogrammed to oct-4 stem cell gene expression by amphibian oocytes. Curr. Biol. 13: 1206-1213.
-
(2003)
Curr. Biol
, vol.13
, pp. 1206-1213
-
-
Byrne, J.A.1
-
17
-
-
0032560827
-
Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei
-
Wakayama, T. et al 1998. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 394: 369-374.
-
(1998)
Nature
, vol.394
, pp. 369-374
-
-
Wakayama, T.1
-
18
-
-
0023128247
-
Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia
-
Schneuwly, S., R. Klemenz & W.J. Gehring 1987. Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia. Nature 325: 816-818.
-
(1987)
Nature
, vol.325
, pp. 816-818
-
-
Schneuwly, S.1
Klemenz, R.2
Gehring, W.J.3
-
19
-
-
0023663888
-
Expression of a single transfected cDNA converts fibroblasts to myoblasts
-
Davis, R.L., H. Weintraub & A.B. Lassar 1987. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 51: 987-1000.
-
(1987)
Cell
, vol.51
, pp. 987-1000
-
-
Davis, R.L.1
Weintraub, H.2
Lassar, A.B.3
-
20
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K. & S. Yamanaka 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
21
-
-
41949134533
-
Generation of pluripotent stem cells from adult mouse liver and stomach cells
-
doi: 10.1126/science.1154884.
-
Aoi, T. et al 2008. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321: 699-702, doi: 10.1126/science.1154884.
-
(2008)
Science
, vol.321
, pp. 699-702
-
-
Aoi, T.1
-
22
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi, K. et al 2007. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
-
23
-
-
43149115856
-
PU.1 and C/EBPalpha/beta convert fibroblasts into macrophage-like cells
-
Feng, R. et al 2008. PU.1 and C/EBPalpha/beta convert fibroblasts into macrophage-like cells. Proc. Natl. Acad. Sci. USA 105: 6057-6062.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 6057-6062
-
-
Feng, R.1
-
24
-
-
69349088117
-
Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex
-
Kajimura, S. et al 2009. Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex. Nature 460: 1154-1158.
-
(2009)
Nature
, vol.460
, pp. 1154-1158
-
-
Kajimura, S.1
-
25
-
-
77955321344
-
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
-
Ieda, M. et al 2010. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 142: 375-386.
-
(2010)
Cell
, vol.142
, pp. 375-386
-
-
Ieda, M.1
-
26
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
Vierbuchen, T. et al 2010. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463: 1035-1041.
-
(2010)
Nature
, vol.463
, pp. 1035-1041
-
-
Vierbuchen, T.1
-
27
-
-
79960637387
-
Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors
-
Huang, P. et al 2011. Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature 475: 386-389.
-
(2011)
Nature
, vol.475
, pp. 386-389
-
-
Huang, P.1
-
28
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Zhou, Q. et al 2008. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 455: 627-632.
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
-
29
-
-
79953881831
-
Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency
-
Anokye-Danso, F. et al 2011. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell 8: 376-388.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 376-388
-
-
Anokye-Danso, F.1
-
30
-
-
79961173182
-
Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions
-
Ambasudhan, R. et al 2011. Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. Cell Stem Cell 9: 113-118.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 113-118
-
-
Ambasudhan, R.1
-
31
-
-
34249908901
-
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
-
Wernig, M. et al 2007. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448: 318-324.
-
(2007)
Nature
, vol.448
, pp. 318-324
-
-
Wernig, M.1
-
32
-
-
34249909232
-
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
-
Maherali, N. et al 2007. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1: 55-70.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 55-70
-
-
Maherali, N.1
-
33
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
Okita, K., T. Ichisaka & S. Yamanaka 2007. Generation of germline-competent induced pluripotent stem cells. Nature 448: 313-317.
-
(2007)
Nature
, vol.448
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
34
-
-
0037478841
-
The first half-century of nuclear transplantation
-
Gurdon, J.B. & J.A. Byrne 2003. The first half-century of nuclear transplantation. Proc. Natl. Acad. Sci. USA 100: 8048-8052.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8048-8052
-
-
Gurdon, J.B.1
Byrne, J.A.2
-
35
-
-
45449094570
-
Reprogramming of pancreatic Beta cells into induced pluripotent stem cells
-
Stadtfeld, M., K. Brennand & K. Hochedlinger 2008. Reprogramming of pancreatic Beta cells into induced pluripotent stem cells. Curr. Biol. 18: 890-894.
-
(2008)
Curr. Biol
, vol.18
, pp. 890-894
-
-
Stadtfeld, M.1
Brennand, K.2
Hochedlinger, K.3
-
36
-
-
41949098160
-
Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
-
Hanna, J. et al 2008. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 133: 250-264.
-
(2008)
Cell
, vol.133
, pp. 250-264
-
-
Hanna, J.1
-
37
-
-
48349095740
-
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
-
Kim, J.B. et al 2008. Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 454: 646-650.
-
(2008)
Nature
, vol.454
, pp. 646-650
-
-
Kim, J.B.1
-
38
-
-
55049122748
-
Reprogramming of neural progenitor cells into iPS cells in the absence of exogenous Sox2 expression
-
Eminli, S. et al 2008. Reprogramming of neural progenitor cells into iPS cells in the absence of exogenous Sox2 expression. Stem Cells 26: 2467-2474.
-
(2008)
Stem Cells
, vol.26
, pp. 2467-2474
-
-
Eminli, S.1
-
39
-
-
66249092408
-
Efficient genetic reprogramming of unmodified somatic neural progenitors uncovers the essential requirement of Oct4 and Klf4
-
Di Stefano, B., A. Prigione & V. Broccoli 2008. Efficient genetic reprogramming of unmodified somatic neural progenitors uncovers the essential requirement of Oct4 and Klf4. Stem Cells Dev. 18: 707-716.
-
(2008)
Stem Cells Dev.
, vol.18
, pp. 707-716
-
-
Di Stefano, B.1
Prigione, A.2
Broccoli, V.3
-
40
-
-
79957587913
-
Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells
-
Tsai, S.Y. et al 2011. Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem Cells 29: 964-971.
-
(2011)
Stem Cells
, vol.29
, pp. 964-971
-
-
Tsai, S.Y.1
-
41
-
-
77149126770
-
Oct4 and klf4 reprogram dermal papilla cells into induced pluripotent stem cells
-
Tsai, S.Y. et al 2010. Oct4 and klf4 reprogram dermal papilla cells into induced pluripotent stem cells Stem Cells. 28: 221-228.
-
(2010)
Stem Cells
, vol.28
, pp. 221-228
-
-
Tsai, S.Y.1
-
42
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu, J. et al 2007. Induced pluripotent stem cell lines derived from human somatic cells. Science 318: 1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
-
43
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
Park, I.H. et al 2008. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451: 141-146.
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.H.1
-
44
-
-
41349090105
-
Generation of human induced pluripotent stem cells from dermal fibroblasts
-
Lowry, W.E. et al 2008. Generation of human induced pluripotent stem cells from dermal fibroblasts. Proc. Natl. Acad. Sci. USA 105: 2883-2888.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 2883-2888
-
-
Lowry, W.E.1
-
45
-
-
50849142559
-
A high-efficiency system for the generation and study of human induced pluripotent stem cells
-
Maherali, N. et al 2008. A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell 3: 340-345.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 340-345
-
-
Maherali, N.1
-
46
-
-
84855404717
-
Concise review: oct4 and more: the reprogramming expressway
-
Sterneckert, J., S. Hoing & H.R. Scholer 2011. Concise review: oct4 and more: the reprogramming expressway. Stem Cells 30: 15-21.
-
(2011)
Stem Cells
, vol.30
, pp. 15-21
-
-
Sterneckert, J.1
Hoing, S.2
Scholer, H.R.3
-
47
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa, M. et al 2008. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 26: 101-106.
-
(2008)
Nat. Biotechnol
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
-
48
-
-
37549008674
-
c-Myc is dispensable for direct reprogramming of mouse fibroblasts
-
Wernig, M. et al 2008. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell 2: 10-12.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 10-12
-
-
Wernig, M.1
-
49
-
-
59649105969
-
Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb
-
Feng, B. et al 2009. Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb. Nat. Cell Biol. 11: 197-203.
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 197-203
-
-
Feng, B.1
-
50
-
-
77956566519
-
A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency
-
Guo, G. & A. Smith 2010. A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency. Development 137: 3185-3192.
-
(2010)
Development
, vol.137
, pp. 3185-3192
-
-
Guo, G.1
Smith, A.2
-
51
-
-
75349088911
-
The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells
-
Heng, J.C. et al 2010. The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells Cell Stem Cell 6: 167-174.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 167-174
-
-
Heng, J.C.1
-
52
-
-
77953727663
-
Chromatin-remodeling components of the BAF complex facilitate reprogramming
-
Singhal, N. et al 2010. Chromatin-remodeling components of the BAF complex facilitate reprogramming. Cell 141: 943-955.
-
(2010)
Cell
, vol.141
, pp. 943-955
-
-
Singhal, N.1
-
53
-
-
82755187396
-
The histone demethylases jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner
-
Wang, T. et al 2011. The histone demethylases jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner. Cell Stem Cell 9: 575-587.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 575-587
-
-
Wang, T.1
-
54
-
-
81055141362
-
Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1
-
Wang, W. et al 2011. Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1. Proc. Natl. Acad. Sci. USA 108: 18283-18288.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 18283-18288
-
-
Wang, W.1
-
55
-
-
77649191794
-
Tbx3 improves the germ-line competency of induced pluripotent stem cells
-
Han, J. et al 2010. Tbx3 improves the germ-line competency of induced pluripotent stem cells. Nature 463: 1096-1100.
-
(2010)
Nature
, vol.463
, pp. 1096-1100
-
-
Han, J.1
-
56
-
-
78149465975
-
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity
-
Chia, N.Y. et al 2010. A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature 468: 316-320.
-
(2010)
Nature
, vol.468
, pp. 316-320
-
-
Chia, N.Y.1
-
57
-
-
79958292714
-
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
-
Maekawa, M. et al 2011. Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1. Nature 474: 225-229.
-
(2011)
Nature
, vol.474
, pp. 225-229
-
-
Maekawa, M.1
-
58
-
-
54949136146
-
Two supporting factors greatly improve the efficiency of human iPSC generation
-
Zhao, Y. et al 2008. Two supporting factors greatly improve the efficiency of human iPSC generation. Cell Stem Cell 3: 475-479.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 475-479
-
-
Zhao, Y.1
-
59
-
-
70349093119
-
Senescence impairs successful reprogramming to pluripotent stem cells
-
Banito, A. et al 2009. Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev. 23: 2134-2139.
-
(2009)
Genes Dev
, vol.23
, pp. 2134-2139
-
-
Banito, A.1
-
60
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
Mikkelsen, T.S. et al 2008. Dissecting direct reprogramming through integrative genomic analysis. Nature 454: 49-55.
-
(2008)
Nature
, vol.454
, pp. 49-55
-
-
Mikkelsen, T.S.1
-
61
-
-
77953086963
-
ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency
-
Pereira, C.F. et al 2010. ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency. Cell Stem Cell 6: 547-556.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 547-556
-
-
Pereira, C.F.1
-
62
-
-
77956320116
-
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
-
Samavarchi-Tehrani, P. et al 2010. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 7: 64-77.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 64-77
-
-
Samavarchi-Tehrani, P.1
-
63
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li, R. et al 2010. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 7: 51-63.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 51-63
-
-
Li, R.1
-
64
-
-
45949109693
-
Mediators of reprogramming: transcription factors and transitions through mitosis
-
Egli, D., G. Birkhoff & K. Eggan 2008. Mediators of reprogramming: transcription factors and transitions through mitosis. Nat. Rev. Mol. Cell Biol. 9: 505-516.
-
(2008)
Nat. Rev. Mol. Cell Biol
, vol.9
, pp. 505-516
-
-
Egli, D.1
Birkhoff, G.2
Eggan, K.3
-
65
-
-
80054726357
-
Direct lineage conversions: unnatural but useful?
-
Vierbuchen, T. & M. Wernig 2011. Direct lineage conversions: unnatural but useful? Nat. Biotechnol. 29: 892-907.
-
(2011)
Nat. Biotechnol
, vol.29
, pp. 892-907
-
-
Vierbuchen, T.1
Wernig, M.2
-
66
-
-
0027164950
-
Ectopic expression of MyoD1 in mice causes prenatal lethalities
-
Faerman, A. et al 1993. Ectopic expression of MyoD1 in mice causes prenatal lethalities. Dev. Dyn. 196: 165-173.
-
(1993)
Dev. Dyn
, vol.196
, pp. 165-173
-
-
Faerman, A.1
-
67
-
-
0025342921
-
Effect of cell history on response to helix-loop-helix family of myogenic regulators
-
Schafer, B.W. et al 1990. Effect of cell history on response to helix-loop-helix family of myogenic regulators. Nature 344: 454-458.
-
(1990)
Nature
, vol.344
, pp. 454-458
-
-
Schafer, B.W.1
-
68
-
-
2542455620
-
Stepwise reprogramming of B cells into macrophages
-
Xie, H. et al 2004. Stepwise reprogramming of B cells into macrophages. Cell 117: 663-676.
-
(2004)
Cell
, vol.117
, pp. 663-676
-
-
Xie, H.1
-
69
-
-
79960854285
-
Induction of human neuronal cells by defined transcription factors
-
Pang, Z.P. et al 2011. Induction of human neuronal cells by defined transcription factors. Nature 476: 220-223.
-
(2011)
Nature
, vol.476
, pp. 220-223
-
-
Pang, Z.P.1
-
70
-
-
80051674431
-
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
-
Caiazzo, M. et al 2011. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature 476: 224-227.
-
(2011)
Nature
, vol.476
, pp. 224-227
-
-
Caiazzo, M.1
-
71
-
-
79959951387
-
Direct conversion of human fibroblasts to dopaminergic neurons
-
Pfisterer, U. et al 2011. Direct conversion of human fibroblasts to dopaminergic neurons. Proc. Natl. Acad. Sci. USA 108: 10343-10348.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 10343-10348
-
-
Pfisterer, U.1
-
72
-
-
79960649307
-
Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
-
Sekiya, S. & A. Suzuki 2011. Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Nature 475: 390-393.
-
(2011)
Nature
, vol.475
, pp. 390-393
-
-
Sekiya, S.1
Suzuki, A.2
-
73
-
-
78649471039
-
Direct conversion of human fibroblasts to multilineage blood progenitors
-
Szabo, E. et al 2010. Direct conversion of human fibroblasts to multilineage blood progenitors. Nature 468: 521-526.
-
(2010)
Nature
, vol.468
, pp. 521-526
-
-
Szabo, E.1
-
74
-
-
79956357347
-
Direct reprogramming of mouse fibroblasts to neural progenitors
-
Kim, J. et al 2011. Direct reprogramming of mouse fibroblasts to neural progenitors. Proc. Natl. Acad. Sci. USA 108: 7838-7843.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 7838-7843
-
-
Kim, J.1
-
75
-
-
79952273710
-
Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
-
Efe, J.A. et al 2011. Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat. Cell Biol. 13: 215-222.
-
(2011)
Nat. Cell Biol
, vol.13
, pp. 215-222
-
-
Efe, J.A.1
-
76
-
-
0034069495
-
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner, M. et al 2000. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 25: 25-29.
-
(2000)
Nat. Genet.
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
-
77
-
-
77649104794
-
Reprogramming towards pluripotency requires AID-dependent DNA demethylation
-
Bhutani, N. et al 2010. Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature 463: 1042-1047.
-
(2010)
Nature
, vol.463
, pp. 1042-1047
-
-
Bhutani, N.1
-
78
-
-
62549128139
-
A census of human transcription factors: function, expression and evolution
-
Vaquerizas, J.M. et al 2009. A census of human transcription factors: function, expression and evolution. Nat. Rev. Genet. 10: 252-263.
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 252-263
-
-
Vaquerizas, J.M.1
-
79
-
-
62549108593
-
The evolution of Fox genes and their role in development and disease
-
Hannenhalli, S. & K.H. Kaestner 2009. The evolution of Fox genes and their role in development and disease. Nat. Rev. Genet. 10: 233-240.
-
(2009)
Nat. Rev. Genet
, vol.10
, pp. 233-240
-
-
Hannenhalli, S.1
Kaestner, K.H.2
-
80
-
-
40249093059
-
A core Klf circuitry regulates self-renewal of embryonic stem cells
-
Jiang, J. et al 2008. A core Klf circuitry regulates self-renewal of embryonic stem cells. Nat. Cell Biol. 10: 353-360.
-
(2008)
Nat. Cell Biol
, vol.10
, pp. 353-360
-
-
Jiang, J.1
-
81
-
-
0026440992
-
Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development
-
Rudnicki, M.A. et al 1992. Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development. Cell 71: 383-390.
-
(1992)
Cell
, vol.71
, pp. 383-390
-
-
Rudnicki, M.A.1
-
82
-
-
0027729729
-
MyoD or Myf-5 is required for the formation of skeletal muscle
-
Rudnicki, M.A. et al 1993. MyoD or Myf-5 is required for the formation of skeletal muscle. Cell 75: 1351-1359.
-
(1993)
Cell
, vol.75
, pp. 1351-1359
-
-
Rudnicki, M.A.1
-
83
-
-
31644436473
-
Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus
-
Williams, R.R. et al 2006. Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus. J. Cell Sci. 119: 132-140.
-
(2006)
J. Cell Sci
, vol.119
, pp. 132-140
-
-
Williams, R.R.1
-
84
-
-
68549136904
-
Pioneer factors, genetic competence, and inductive signaling: programming liver and pancreas progenitors from the endoderm
-
Zaret, K.S. et al 2008. Pioneer factors, genetic competence, and inductive signaling: programming liver and pancreas progenitors from the endoderm. Cold Spring Harb. Symp. Quant. Biol. 73: 119-126.
-
(2008)
Cold Spring Harb. Symp. Quant. Biol
, vol.73
, pp. 119-126
-
-
Zaret, K.S.1
-
85
-
-
80455144479
-
Pioneer transcription factors: establishing competence for gene expression
-
Zaret, K.S. & J.S. Carroll 2011. Pioneer transcription factors: establishing competence for gene expression. Genes Dev. 25: 2227-2241.
-
(2011)
Genes Dev
, vol.25
, pp. 2227-2241
-
-
Zaret, K.S.1
Carroll, J.S.2
-
86
-
-
33645227508
-
The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure
-
Yan, J. et al 2006. The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure. Mol. Cell Biol. 26: 155-168.
-
(2006)
Mol. Cell Biol
, vol.26
, pp. 155-168
-
-
Yan, J.1
-
87
-
-
77949977555
-
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
-
Ghisletti, S. et al 2010. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 32: 317-328.
-
(2010)
Immunity
, vol.32
, pp. 317-328
-
-
Ghisletti, S.1
-
88
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz, S. et al 2010. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38: 576-589.
-
(2010)
Mol. Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
-
89
-
-
80054746874
-
CCAAT/enhancer binding protein alpha (C/EBP(alpha))-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation
-
Di Tullio, A. et al 2011. CCAAT/enhancer binding protein alpha (C/EBP(alpha))-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation. Proc. Natl. Acad. Sci. USA 108: 17016-17021.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 17016-17021
-
-
Di Tullio, A.1
-
90
-
-
70350596826
-
A robust and highly efficient immune cell reprogramming system
-
Bussmann, L.H. et al 2009. A robust and highly efficient immune cell reprogramming system. Cell Stem Cell 5: 554-566.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 554-566
-
-
Bussmann, L.H.1
-
91
-
-
71449109765
-
Direct cell reprogramming is a stochastic process amenable to acceleration
-
Hanna, J. et al 2009. Direct cell reprogramming is a stochastic process amenable to acceleration. Nature 462: 595-601.
-
(2009)
Nature
, vol.462
, pp. 595-601
-
-
Hanna, J.1
-
92
-
-
39349106325
-
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development
-
Murry, C.E. & G. Keller 2008. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 132: 661-680.
-
(2008)
Cell
, vol.132
, pp. 661-680
-
-
Murry, C.E.1
Keller, G.2
-
93
-
-
0021891053
-
The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium
-
Doetschman, T.C. et al 1985. The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J. Embryol. Exp. Morphol. 87: 27-45.
-
(1985)
J. Embryol. Exp. Morphol
, vol.87
, pp. 27-45
-
-
Doetschman, T.C.1
-
94
-
-
0027389676
-
Hematopoietic commitment during embryonic stem cell differentiation in culture
-
Keller, G. et al 1993. Hematopoietic commitment during embryonic stem cell differentiation in culture. Mol. Cell Biol. 13: 473-486.
-
(1993)
Mol. Cell Biol
, vol.13
, pp. 473-486
-
-
Keller, G.1
-
95
-
-
0033036971
-
Cbfa2 is required for the formation of intra-aortic hematopoietic clusters
-
North, T. et al 1999. Cbfa2 is required for the formation of intra-aortic hematopoietic clusters. Development 126: 2563-2575.
-
(1999)
Development
, vol.126
, pp. 2563-2575
-
-
North, T.1
-
96
-
-
0029006696
-
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
-
Shalaby, F. et al 1995. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376: 62-66.
-
(1995)
Nature
, vol.376
, pp. 62-66
-
-
Shalaby, F.1
-
97
-
-
0024381667
-
Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD
-
Weintraub, H. et al 1989. Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. Proc. Natl. Acad. Sci. USA 86: 5434-5438.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5434-5438
-
-
Weintraub, H.1
|