-
1
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by def ned factors
-
Takahashi K and S Yamanaka. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by def ned factors. Cell 126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
2
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by def ned factors
-
Takahashi K, K Tanabe, M Ohnuki, M Narita, T Ichisaka, K Tomoda and S Yamanaka. (2007). Induction of pluripotent stem cells from adult human fibroblasts by def ned factors. Cell 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
3
-
-
34249908901
-
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
-
Wernig M, A Meissner, R Foreman, T Brambrink, M Ku, K Hochedlinger, BE Bernstein and R Jaenisch. (2007). In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448:318-324.
-
(2007)
Nature
, vol.448
, pp. 318-324
-
-
Wernig, M.1
Meissner, A.2
Foreman, R.3
Brambrink, T.4
Ku, M.5
Hochedlinger, K.6
Bernstein, B.E.7
Jaenisch, R.8
-
4
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, MA Vodyanik, K Smuga-Otto, J Antosiewicz-Bourget, JL Frane, S Tian, J Nie, GA Jonsdottir, V Ruotti, R Stewart, Slukvin, II and JA Thomson. (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science 318:1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
Nie, J.7
Jonsdottir, G.A.8
Ruotti, V.9
Stewart, R.10
Slukvin II11
Thomson, J.A.12
-
5
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with def ned factors
-
Park IH, R Zhao, JA West, A Yabuuchi, H Huo, TA Ince, PH Lerou, MW Lensch and GQ Daley. (2008). Reprogramming of human somatic cells to pluripotency with def ned factors. Nature 451:141-146.
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.H.1
Zhao, R.2
West, J.A.3
Yabuuchi, A.4
Huo, H.5
Ince, T.A.6
Lerou, P.H.7
Lensch, M.W.8
Daley, G.Q.9
-
6
-
-
39149115929
-
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
-
Stadtfeld M, N Maherali, DT Breault and K Hochedlinger. (2008). Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell 2:230-240.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 230-240
-
-
Stadtfeld, M.1
Maherali, N.2
Breault, D.T.3
Hochedlinger, K.4
-
7
-
-
34249909232
-
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
-
Maherali N, R Sridharan, W Xie, J Utikal, S Eminli, K Arnold, M Stadtfeld, R Yachechko, J Tchieu, R Jaenisch, K Plath and K Hochedlinger. (2007). Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 1:55-70.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 55-70
-
-
Maherali, N.1
Sridharan, R.2
Xie, W.3
Utikal, J.4
Eminli, S.5
Arnold, K.6
Stadtfeld, M.7
Yachechko, R.8
Tchieu, J.9
Jaenisch, R.10
Plath, K.11
Hochedlinger, K.12
-
8
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
Okita K, T Ichisaka and S Yamanaka. (2007). Generation of germline-competent induced pluripotent stem cells. Nature 448:313 -317.
-
(2007)
Nature
, vol.448
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
9
-
-
37549030199
-
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
-
Hanna J, M Wernig, S Markoulaki, CW Sun, A Meissner, JP Cassady, C Beard, T Brambrink, LC Wu, TM Townes and R Jaenisch. (2007). Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 318:1920 -1923.
-
(2007)
Science
, vol.318
, pp. 1920-1923
-
-
Hanna, J.1
Wernig, M.2
Markoulaki, S.3
Sun, C.W.4
Meissner, A.5
Cassady, J.P.6
Beard, C.7
Brambrink, T.8
Wu, L.C.9
Townes, T.M.10
Jaenisch, R.11
-
10
-
-
42649130264
-
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
-
Wernig M, JP Zhao, J Pruszak, E Hedlund, D Fu, F Soldner, V Broccoli, M Constantine-Paton, O Isacson and R Jaenisch. (2008). Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc Natl Acad Sci USA 105:5856 - 5861.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 5856-5861
-
-
Wernig, M.1
Zhao, J.P.2
Pruszak, J.3
Hedlund, E.4
Fu, D.5
Soldner, F.6
Broccoli, V.7
Constantine-Paton, M.8
Isacson, O.9
Jaenisch, R.10
-
11
-
-
34548445454
-
Generation of induced pluripotent stem cells in the absence of drug selection
-
Blelloch R, M Venere, J Yen and M Ramalho-Santos. (2007). Generation of induced pluripotent stem cells in the absence of drug selection. Cell Stem Cell 1:245-247.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 245-247
-
-
Blelloch, R.1
Venere, M.2
Yen, J.3
Ramalho-Santos, M.4
-
12
-
-
35148845584
-
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
-
Meissner A, M Wernig and R Jaenisch. (2007). Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat Biotechnol 25:1177-1181.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1177-1181
-
-
Meissner, A.1
Wernig, M.2
Jaenisch, R.3
-
14
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa M, M Koyanagi, K Tanabe, K Takahashi, T Ichisaka, T Aoi, K Okita, Y Mochiduki, N Takizawa and S Yamanaka. (2008). Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 26:101-106.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
Koyanagi, M.2
Tanabe, K.3
Takahashi, K.4
Ichisaka, T.5
Aoi, T.6
Okita, K.7
Mochiduki, Y.8
Takizawa, N.9
Yamanaka, S.10
-
15
-
-
48349122654
-
Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells
-
Ruau D, R Ensenat-Waser, TC Dinger, DS Vallabhapurapu, A Rolletschek, C Hacker, T Hieronymus, AM Wobus, AM Muller and M Zenke. (2008). Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells. Stem Cells 26:920-926.
-
(2008)
Stem Cells
, vol.26
, pp. 920-926
-
-
Ruau, D.1
Ensenat-Waser, R.2
Dinger, T.C.3
Vallabhapurapu, D.S.4
Rolletschek, A.5
Hacker, C.6
Hieronymus, T.7
Wobus, A.M.8
Muller, A.M.9
Zenke, M.10
-
16
-
-
44349103591
-
A combined chemical and genetic approach for the generation of induced pluripotent stem cells
-
Shi Y, JT Do, C Desponts, HS Hahm, HR Scholer and S Ding. (2008). A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell 2:525-528.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 525-528
-
-
Shi, Y.1
Do, J.T.2
Desponts, C.3
Hahm, H.S.4
Scholer, H.R.5
Ding, S.6
-
17
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
Mikkelsen TS, J Hanna, X Zhang, M Ku, M Wernig, P Schorderet, BE Bernstein, R Jaenisch, ES Lander and A Meissner. (2008). Dissecting direct reprogramming through integrative genomic analysis. Nature 454:766-770.
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
Ku, M.4
Wernig, M.5
Schorderet, P.6
Bernstein, B.E.7
Jaenisch, R.8
Lander, E.S.9
Meissner, A.10
-
18
-
-
45449094570
-
Reprogramming of pancreatic beta cells into induced pluripotent stem cells
-
Stadtfeld M, K Brennand and K Hochedlinger. (2008). Reprogramming of pancreatic beta cells into induced pluripotent stem cells. Curr Biol 18:890-894.
-
(2008)
Curr Biol
, vol.18
, pp. 890-894
-
-
Stadtfeld, M.1
Brennand, K.2
Hochedlinger, K.3
-
19
-
-
41949134533
-
Generation of pluripotent stem cells from adult mouse liver and stomach cells
-
Aoi T, K Yae, M Nakagawa, T Ichisaka, K Okita, K Takahashi, T Chiba and S Yamanaka. (2008). Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321:699-702.
-
(2008)
Science
, vol.321
, pp. 699-702
-
-
Aoi, T.1
Yae, K.2
Nakagawa, M.3
Ichisaka, T.4
Okita, K.5
Takahashi, K.6
Chiba, T.7
Yamanaka, S.8
-
20
-
-
41949098160
-
Direct repro-gramming of terminally differentiated mature B lymphocytes to pluripotency
-
Hanna J, S Markoulaki, P Schorderet, BW Carey, C Beard, M Wernig, MP Creyghton, EJ Steine, JP Cassady, R Foreman, CJ Lengner, JA Dausman and R Jaenisch. (2008). Direct repro-gramming of terminally differentiated mature B lymphocytes to pluripotency. Cell 133:250-264.
-
(2008)
Cell
, vol.133
, pp. 250-264
-
-
Hanna, J.1
Markoulaki, S.2
Schorderet, P.3
Carey, B.W.4
Beard, C.5
Wernig, M.6
Creyghton, M.P.7
Steine, E.J.8
Cassady, J.P.9
Foreman, R.10
Lengner, C.J.11
Dausman, J.A.12
Jaenisch, R.13
-
21
-
-
33745525505
-
Reprogramming eff ciency following somatic cell nuclear transfer is inf uenced by the differentiation and methylation state of the donor nucleus
-
Blelloch R, Z Wang, A Meissner, S Pollard, A Smith and R Jaenisch. (2006). Reprogramming eff ciency following somatic cell nuclear transfer is inf uenced by the differentiation and methylation state of the donor nucleus. Stem Cells 24:2007-2013.
-
(2006)
Stem Cells
, vol.24
, pp. 2007-2013
-
-
Blelloch, R.1
Wang, Z.2
Meissner, A.3
Pollard, S.4
Smith, A.5
Jaenisch, R.6
-
22
-
-
0029860591
-
Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis
-
Weiss S, C Dunne, J Hewson, C Wohl, M Wheatley, AC Peterson and BA Reynolds. (1996). Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis. J Neurosci 16:7599-7609.
-
(1996)
J Neurosci
, vol.16
, pp. 7599-7609
-
-
Weiss, S.1
Dunne, C.2
Hewson, J.3
Wohl, C.4
Wheatley, M.5
Peterson, A.C.6
Reynolds, B.A.7
-
23
-
-
0035499887
-
The development of neural stem cells
-
Temple S. (2001). The development of neural stem cells. Nature 414:112-117.
-
(2001)
Nature
, vol.414
, pp. 112-117
-
-
Temple, S.1
-
24
-
-
0029971286
-
Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor
-
Gritti A, EA Parati, L Cova, P Frolichsthal, R Galli, E Wanke, L Faravelli, DJ Morassutti, F Roisen, DD Nickel and AL Vescovi. (1996). Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. J Neurosci 16:1091-1100.
-
(1996)
J Neurosci
, vol.16
, pp. 1091-1100
-
-
Gritti, A.1
Parati, E.A.2
Cova, L.3
Frolichsthal, P.4
Galli, R.5
Wanke, E.6
Faravelli, L.7
Morassutti, D.J.8
Roisen, F.9
Nickel, D.D.10
Vescovi, A.L.11
-
25
-
-
33745484621
-
Embryonic stem-derived versus somatic neural stem cells: A comparative analysis of their developmental potential and molecular phenotype
-
Colombo E, SG Giannelli, R Galli, E Tagliafico, C Foroni, E Tenedini, S Ferrari, S Ferrari, G Corte, A Vescovi, G Cossu and V Broccoli. (2006). Embryonic stem-derived versus somatic neural stem cells: a comparative analysis of their developmental potential and molecular phenotype. Stem Cells 24:825-834.
-
(2006)
Stem Cells
, vol.24
, pp. 825-834
-
-
Colombo, E.1
Giannelli, S.G.2
Galli, R.3
Tagliafico, E.4
Foroni, C.5
Tenedini, E.6
Ferrari, S.7
Ferrari, S.8
Corte, G.9
Vescovi, A.10
Cossu, G.11
Broccoli, V.12
-
26
-
-
34250192881
-
Generation of a def ned and uniform population of CNS progenitors and neurons from mouse embryonic stem cells
-
Bibel M, J Richter, E Lacroix and YA Barde. (2007). Generation of a def ned and uniform population of CNS progenitors and neurons from mouse embryonic stem cells. Nat Protoc 2:1034-1043.
-
(2007)
Nat Protoc
, vol.2
, pp. 1034-1043
-
-
Bibel, M.1
Richter, J.2
Lacroix, E.3
Barde, Y.A.4
-
27
-
-
0033638174
-
Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity
-
Kawasaki H, K Mizuseki, S Nishikawa, S Kaneko, Y Kuwana, S Nakanishi, SI Nishikawa and Y Sasai. (2000). Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 28:31-40.
-
(2000)
Neuron
, vol.28
, pp. 31-40
-
-
Kawasaki, H.1
Mizuseki, K.2
Nishikawa, S.3
Kaneko, S.4
Kuwana, Y.5
Nakanishi, S.6
Nishikawa, S.I.7
Sasai, Y.8
-
28
-
-
10744229091
-
Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice
-
Barberi T, P Klivenyi, NY Calingasan, H Lee, H Kawamata, K Loonam, AL Perrier, J Bruses, ME Rubio, N Topf, V Tabar, NL Harrison, MF Beal, MA Moore and L Studer. (2003). Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol 21:1200-1207.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 1200-1207
-
-
Barberi, T.1
Klivenyi, P.2
Calingasan, N.Y.3
Lee, H.4
Kawamata, H.5
Loonam, K.6
Perrier, A.L.7
Bruses, J.8
Rubio, M.E.9
Topf, N.10
Tabar, V.11
Harrison, N.L.12
Beal, M.F.13
Moore, M.A.14
Studer, L.15
-
29
-
-
40249093059
-
A core Klf circuitry regulates selfrenewal of embryonic stem cells
-
Jiang J, YS Chan, YH Loh, J Cai, GQ Tong, CA Lim, P Robson, S Zhong and HH Ng. (2008). A core Klf circuitry regulates selfrenewal of embryonic stem cells. Nat Cell Biol 10:353-360.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 353-360
-
-
Jiang, J.1
Chan, Y.S.2
Loh, Y.H.3
Cai, J.4
Tong, G.Q.5
Lim, C.A.6
Robson, P.7
Zhong, S.8
Ng, H.H.9
-
30
-
-
0033040497
-
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
-
Doetsch F, I Caille, DA Lim, JM Garcia-Verdugo and A Alvarez-Buylla. (1999). Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97:703-716.
-
(1999)
Cell
, vol.97
, pp. 703-716
-
-
Doetsch, F.1
Caille, I.2
Lim, D.A.3
Garcia-Verdugo, J.M.4
Alvarez-Buylla, A.5
-
31
-
-
0242321829
-
The glial identity of neural stem cells
-
Doetsch F. (2003). The glial identity of neural stem cells. Nat Neurosci 6:1127-1134.
-
(2003)
Nat Neurosci
, vol.6
, pp. 1127-1134
-
-
Doetsch, F.1
-
33
-
-
24944484633
-
Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
-
Conti L, SM Pollard, T Gorba, E Reitano, M Toselli, G Biella, Y Sun, S Sanzone, QL Ying, E Cattaneo and A Smith. (2005). Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biol 3:e283.
-
(2005)
PLoS Biol
, vol.3
-
-
Conti, L.1
Pollard, S.M.2
Gorba, T.3
Reitano, E.4
Toselli, M.5
Biella, G.6
Sun, Y.7
Sanzone, S.8
Ying, Q.L.9
Cattaneo, E.10
Smith, A.11
-
34
-
-
33747587820
-
Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro
-
Chung S, BS Shin, M Hwang, T Lardaro, UJ Kang, O Isacson and KS Kim. (2006). Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro. Stem Cells 24:1583-1593.
-
(2006)
Stem Cells
, vol.24
, pp. 1583-1593
-
-
Chung, S.1
Shin, B.S.2
Hwang, M.3
Lardaro, T.4
Kang, U.J.5
Isacson, O.6
Kim, K.S.7
-
36
-
-
48349095740
-
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
-
Kim JB, H Zaehres, G Wu, L Gentile, K Ko, V Sebastiano, MJ Arauzo-Bravo, D Ruau, DW Han, M Zenke and HR Scholer. (2008). Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 454:646-650.
-
(2008)
Nature
, vol.454
, pp. 646-650
-
-
Kim, J.B.1
Zaehres, H.2
Wu, G.3
Gentile, L.4
Ko, K.5
Sebastiano, V.6
Arauzo-Bravo, M.J.7
Ruau, D.8
Han, D.W.9
Zenke, M.10
Scholer, H.R.11
-
37
-
-
46949085597
-
Induction of pluripotent stem cells by def ned factors is greatly improved by small-molecule compounds
-
Huangfu D, R Maehr, W Guo, A Eijkelenboom, M Snitow, AE Chen and DA Melton. (2008). Induction of pluripotent stem cells by def ned factors is greatly improved by small-molecule compounds. Nat Biotechnol 26:795-797.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 795-797
-
-
Huangfu, D.1
Maehr, R.2
Guo, W.3
Eijkelenboom, A.4
Snitow, M.5
Chen, A.E.6
Melton, D.A.7
-
38
-
-
54949141718
-
G9a and Jhdm2a regulate embryonic stem cell fusioninduced reprogramming of adult neural stem cells
-
Ma DK, CH Chiang, K Ponnusamy, GL Ming and H Song. (2008). G9a and Jhdm2a regulate embryonic stem cell fusioninduced reprogramming of adult neural stem cells. Stem Cells 26:2131-2141.
-
(2008)
Stem Cells
, vol.26
, pp. 2131-2141
-
-
Ma, D.K.1
Chiang, C.H.2
Ponnusamy, K.3
Ming, G.L.4
Song, H.5
-
39
-
-
39149130361
-
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
-
Jaenisch R and R Young. (2008). Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132:567-582.
-
(2008)
Cell
, vol.132
, pp. 567-582
-
-
Jaenisch, R.1
Young, R.2
-
40
-
-
0025352402
-
A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo
-
Rosner MH, MA Vigano, K Ozato, PM Timmons, F Poirier, PW Rigby and LM Staudt. (1990). A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature 345:686-692.
-
(1990)
Nature
, vol.345
, pp. 686-692
-
-
Rosner, M.H.1
Vigano, M.A.2
Ozato, K.3
Timmons, P.M.4
Poirier, F.5
Rigby, P.W.6
Staudt, L.M.7
-
41
-
-
0037130961
-
A stem cell molecular signature
-
Ivanova NB, JT Dimos, C Schaniel, JA Hackney, KA Moore and IR Lemischka. (2002). A stem cell molecular signature. Science 298:601-604.
-
(2002)
Science
, vol.298
, pp. 601-604
-
-
Ivanova, N.B.1
Dimos, J.T.2
Schaniel, C.3
Hackney, J.A.4
Moore, K.A.5
Lemischka, I.R.6
-
42
-
-
48749109906
-
Improved eff ciency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts
-
Mali P, Z Ye, HH Hommond, X Yu, J Lin, G Chen, J Zou and L Cheng. (2008). Improved eff ciency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells 26:1998-2005.
-
(2008)
Stem Cells
, vol.26
, pp. 1998-2005
-
-
Mali, P.1
Ye, Z.2
Hommond, H.H.3
Yu, X.4
Lin, J.5
Chen, G.6
Zou, J.7
Cheng, L.8
|