메뉴 건너뛰기




Volumn 10, Issue 3, 2012, Pages 136-141

Microarray analysis of ageing-related signatures and their expression in tumors based on a computational biology approach

Author keywords

Ageing related signatures; Bioinformatics; Gene expression profiling; Microarray; Tumor

Indexed keywords

ADULT; AGED; AGING; ARTICLE; BIOLOGY; GENE EXPRESSION; GENE FUNCTION; GENOME ANALYSIS; HUMAN; MAJOR CLINICAL STUDY; MICROARRAY ANALYSIS; NEOPLASM; PHENOTYPE;

EID: 84865333249     PISSN: 16720229     EISSN: 22103244     Source Type: Journal    
DOI: 10.1016/j.gpb.2012.01.001     Document Type: Article
Times cited : (4)

References (55)
  • 1
    • 3042631024 scopus 로고    scopus 로고
    • Gene regulation and DNA damage in the ageing human brain
    • Lu T., Pan Y., Kao S.Y., Li C., Kohane I., Chan J., et al. Gene regulation and DNA damage in the ageing human brain. Nature 2004, 429:883-891.
    • (2004) Nature , vol.429 , pp. 883-891
    • Lu, T.1    Pan, Y.2    Kao, S.Y.3    Li, C.4    Kohane, I.5    Chan, J.6
  • 4
    • 13244291381 scopus 로고    scopus 로고
    • Downregulation of gene expression in the ageing lens: a possible contributory factor in senile cataract
    • Segev F., Mor O., Segev A., Belkin M., Assia E.I. Downregulation of gene expression in the ageing lens: a possible contributory factor in senile cataract. Eye (Lond) 2005, 19:80-85.
    • (2005) Eye (Lond) , vol.19 , pp. 80-85
    • Segev, F.1    Mor, O.2    Segev, A.3    Belkin, M.4    Assia, E.I.5
  • 6
    • 11844269955 scopus 로고    scopus 로고
    • Identification and functional clustering of global gene expression differences between age-related cataract and clear human lenses and aged human lenses
    • Hawse J.R., Hejtmancik J.F., Horwitz J., Kantorow M. Identification and functional clustering of global gene expression differences between age-related cataract and clear human lenses and aged human lenses. Exp Eye Res 2004, 79:935-940.
    • (2004) Exp Eye Res , vol.79 , pp. 935-940
    • Hawse, J.R.1    Hejtmancik, J.F.2    Horwitz, J.3    Kantorow, M.4
  • 7
    • 0346039152 scopus 로고    scopus 로고
    • Identification and functional clustering of global gene expression differences between human age-related cataract and clear lenses
    • Hawse J.R., Hejtmancik J.F., Huang Q., Sheets N.L., Hosack D.A., Lempicki R.A., et al. Identification and functional clustering of global gene expression differences between human age-related cataract and clear lenses. Mol Vis 2003, 9:515-537.
    • (2003) Mol Vis , vol.9 , pp. 515-537
    • Hawse, J.R.1    Hejtmancik, J.F.2    Huang, Q.3    Sheets, N.L.4    Hosack, D.A.5    Lempicki, R.A.6
  • 8
    • 32844464041 scopus 로고    scopus 로고
    • Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling
    • Melk A., Mansfield E.S., Hsieh S.C., Hernandez-Boussard T., Grimm P., Rayner D.C., et al. Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling. Kidney Int 2005, 68:2667-2679.
    • (2005) Kidney Int , vol.68 , pp. 2667-2679
    • Melk, A.1    Mansfield, E.S.2    Hsieh, S.C.3    Hernandez-Boussard, T.4    Grimm, P.5    Rayner, D.C.6
  • 11
    • 1342265400 scopus 로고    scopus 로고
    • Skeletal muscle gene expression profiles in 20-29 year old and 65-71 year old women
    • Welle S., Brooks A.I., Delehanty J.M., Needler N., Bhatt K., Shah B., et al. Skeletal muscle gene expression profiles in 20-29 year old and 65-71 year old women. Exp Gerontol 2004, 39:369-377.
    • (2004) Exp Gerontol , vol.39 , pp. 369-377
    • Welle, S.1    Brooks, A.I.2    Delehanty, J.M.3    Needler, N.4    Bhatt, K.5    Shah, B.6
  • 12
    • 33746621756 scopus 로고    scopus 로고
    • Transcriptional profiling of aging in human muscle reveals a common aging signature
    • Zahn J.M., Sonu R., Vogel H., Crane E., Mazan-Mamczarz K., Rabkin R., et al. Transcriptional profiling of aging in human muscle reveals a common aging signature. PLoS Genet 2006, 2:e115.
    • (2006) PLoS Genet , vol.2
    • Zahn, J.M.1    Sonu, R.2    Vogel, H.3    Crane, E.4    Mazan-Mamczarz, K.5    Rabkin, R.6
  • 14
    • 26944494588 scopus 로고    scopus 로고
    • Genetic dissection of gene expression observed in whole blood samples of elderly Danish twins
    • Tan Q., Christensen K., Christiansen L., Frederiksen H., Bathum L., Dahlgaard J., et al. Genetic dissection of gene expression observed in whole blood samples of elderly Danish twins. Hum Genet 2005, 117:267-274.
    • (2005) Hum Genet , vol.117 , pp. 267-274
    • Tan, Q.1    Christensen, K.2    Christiansen, L.3    Frederiksen, H.4    Bathum, L.5    Dahlgaard, J.6
  • 15
    • 0037288292 scopus 로고    scopus 로고
    • Influence of ageing, heat shock treatment and in vivo total antioxidant status on gene-expression profile and protein synthesis in human peripheral lymphocytes
    • Visala Rao D., Boyle G.M., Parsons P.G., Watson K., Jones G.L. Influence of ageing, heat shock treatment and in vivo total antioxidant status on gene-expression profile and protein synthesis in human peripheral lymphocytes. Mech Ageing Dev 2003, 124:55-69.
    • (2003) Mech Ageing Dev , vol.124 , pp. 55-69
    • Visala Rao, D.1    Boyle, G.M.2    Parsons, P.G.3    Watson, K.4    Jones, G.L.5
  • 16
    • 63549135460 scopus 로고    scopus 로고
    • Meta-analysis of age-related gene expression profiles identifies common signatures of aging
    • de Magalhaes J.P., Curado J., Church G.M. Meta-analysis of age-related gene expression profiles identifies common signatures of aging. Bioinformatics 2009, 25:875-881.
    • (2009) Bioinformatics , vol.25 , pp. 875-881
    • de Magalhaes, J.P.1    Curado, J.2    Church, G.M.3
  • 17
    • 0842267618 scopus 로고    scopus 로고
    • Comparing genomic expression patterns across species identifies shared transcriptional profile in aging
    • McCarroll S.A., Murphy C.T., Zou S., Pletcher S.D., Chin C.S., Jan Y.N., et al. Comparing genomic expression patterns across species identifies shared transcriptional profile in aging. Nat Genet 2004, 36:197-204.
    • (2004) Nat Genet , vol.36 , pp. 197-204
    • McCarroll, S.A.1    Murphy, C.T.2    Zou, S.3    Pletcher, S.D.4    Chin, C.S.5    Jan, Y.N.6
  • 19
    • 34250310936 scopus 로고    scopus 로고
    • Telomerase and telomere dynamics in ageing and cancer: current status and future directions
    • Sampedro Camarena F., Cano Serral G., Sampedro Santalo F. Telomerase and telomere dynamics in ageing and cancer: current status and future directions. Clin Transl Oncol 2007, 9:145-154.
    • (2007) Clin Transl Oncol , vol.9 , pp. 145-154
    • Sampedro Camarena, F.1    Cano Serral, G.2    Sampedro Santalo, F.3
  • 20
    • 23644460701 scopus 로고    scopus 로고
    • Hormones and growth factors regulate telomerase activity in ageing and cancer
    • Bayne S., Liu J.P. Hormones and growth factors regulate telomerase activity in ageing and cancer. Mol Cell Endocrinol 2005, 240:11-22.
    • (2005) Mol Cell Endocrinol , vol.240 , pp. 11-22
    • Bayne, S.1    Liu, J.P.2
  • 21
    • 22944488871 scopus 로고    scopus 로고
    • Telomeres and human disease: ageing, cancer and beyond
    • Blasco M.A. Telomeres and human disease: ageing, cancer and beyond. Nat Rev Genet 2005, 6:611-622.
    • (2005) Nat Rev Genet , vol.6 , pp. 611-622
    • Blasco, M.A.1
  • 23
    • 35148879733 scopus 로고    scopus 로고
    • Ageing or cancer: a review on the role of caretakers and gatekeepers
    • van Heemst D., den Reijer P.M., Westendorp R.G.J. Ageing or cancer: a review on the role of caretakers and gatekeepers. Eur J Cancer 2007, 43:2144-2152.
    • (2007) Eur J Cancer , vol.43 , pp. 2144-2152
    • van Heemst, D.1    den Reijer, P.M.2    Westendorp, R.G.J.3
  • 24
    • 42449152382 scopus 로고    scopus 로고
    • The tumor suppressor p53: cancer and aging
    • Feng Z., Hu W., Rajagopal G., Levine A.J. The tumor suppressor p53: cancer and aging. Cell Cycle 2008, 7:842-847.
    • (2008) Cell Cycle , vol.7 , pp. 842-847
    • Feng, Z.1    Hu, W.2    Rajagopal, G.3    Levine, A.J.4
  • 25
    • 0037180245 scopus 로고    scopus 로고
    • Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism?
    • Chinnery P.F., Samuels D.C., Elson J., Turnbull D.M. Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism?. Lancet 2002, 360:1323-1325.
    • (2002) Lancet , vol.360 , pp. 1323-1325
    • Chinnery, P.F.1    Samuels, D.C.2    Elson, J.3    Turnbull, D.M.4
  • 26
    • 33744465025 scopus 로고    scopus 로고
    • Mitochondria damage checkpoint, aging, and cancer
    • Singh K.K. Mitochondria damage checkpoint, aging, and cancer. Ann NY Acad Sci 2006, 1067:182-190.
    • (2006) Ann NY Acad Sci , vol.1067 , pp. 182-190
    • Singh, K.K.1
  • 27
    • 80053558155 scopus 로고    scopus 로고
    • The importance of mitochondrial DNA in aging and cancer
    • Desler C., Marcker M.L., Singh K.K., Rasmussen L.J. The importance of mitochondrial DNA in aging and cancer. J Aging Res 2011, 2011:407536.
    • (2011) J Aging Res , vol.2011 , pp. 407536
    • Desler, C.1    Marcker, M.L.2    Singh, K.K.3    Rasmussen, L.J.4
  • 28
    • 79956294799 scopus 로고    scopus 로고
    • Forkhead transcription factors: key players in health and disease
    • Benayoun B.A., Caburet S., Veitia R.A. Forkhead transcription factors: key players in health and disease. Trends Genet 2011, 27:224-232.
    • (2011) Trends Genet , vol.27 , pp. 224-232
    • Benayoun, B.A.1    Caburet, S.2    Veitia, R.A.3
  • 29
    • 37349096366 scopus 로고    scopus 로고
    • FOXO transcription factors in ageing and cancer
    • Greer E.L., Brunet A. FOXO transcription factors in ageing and cancer. Acta Physiol (Oxf) 2008, 192:19-28.
    • (2008) Acta Physiol (Oxf) , vol.192 , pp. 19-28
    • Greer, E.L.1    Brunet, A.2
  • 30
  • 31
    • 60949100188 scopus 로고    scopus 로고
    • Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications
    • Mimeault M., Batra S.K. Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications. Ageing Res Rev 2009, 8:94-112.
    • (2009) Ageing Res Rev , vol.8 , pp. 94-112
    • Mimeault, M.1    Batra, S.K.2
  • 32
    • 33847654804 scopus 로고    scopus 로고
    • Effect of stem cell turnover rates on protection against cancer and aging
    • Wodarz D. Effect of stem cell turnover rates on protection against cancer and aging. J Theor Biol 2007, 245:449-458.
    • (2007) J Theor Biol , vol.245 , pp. 449-458
    • Wodarz, D.1
  • 33
    • 0037369324 scopus 로고    scopus 로고
    • Human stem cells as targets for the aging and diseases of aging processes
    • Trosko J.E. Human stem cells as targets for the aging and diseases of aging processes. Med Hypotheses 2003, 60:439-447.
    • (2003) Med Hypotheses , vol.60 , pp. 439-447
    • Trosko, J.E.1
  • 34
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang D.W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009, 4:44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 35
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
    • Huang D.W., Sherman B.T., Lempicki R.A. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 2009, 37:1-13.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1-13
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 36
    • 0037470501 scopus 로고    scopus 로고
    • The endocrine regulation of aging by insulin-like signals
    • Tatar M., Bartke A., Antebi A. The endocrine regulation of aging by insulin-like signals. Science 2003, 299:1346-1351.
    • (2003) Science , vol.299 , pp. 1346-1351
    • Tatar, M.1    Bartke, A.2    Antebi, A.3
  • 37
    • 0142052858 scopus 로고    scopus 로고
    • Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans
    • Barbieri M., Bonafe M., Franceschi C., Paolisso G. Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. Am J Physiol Endocrinol Metab 2003, 285:E1064-E1071.
    • (2003) Am J Physiol Endocrinol Metab , vol.285
    • Barbieri, M.1    Bonafe, M.2    Franceschi, C.3    Paolisso, G.4
  • 38
    • 0027154719 scopus 로고
    • Expression of heat shock protein 70 is altered by age and diet at the level of transcription
    • Heydari A.R., Wu B., Takahashi R., Strong R., Richardson A. Expression of heat shock protein 70 is altered by age and diet at the level of transcription. Mol Cell Biol 1993, 13:2909-2918.
    • (1993) Mol Cell Biol , vol.13 , pp. 2909-2918
    • Heydari, A.R.1    Wu, B.2    Takahashi, R.3    Strong, R.4    Richardson, A.5
  • 39
    • 14644435819 scopus 로고    scopus 로고
    • Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms
    • Rohde M., Daugaard M., Jensen M.H., Helin K., Nylandsted J., Jaattela M. Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms. Genes Dev 2005, 19:570-582.
    • (2005) Genes Dev , vol.19 , pp. 570-582
    • Rohde, M.1    Daugaard, M.2    Jensen, M.H.3    Helin, K.4    Nylandsted, J.5    Jaattela, M.6
  • 40
    • 0030570416 scopus 로고    scopus 로고
    • Alterations of c-fos gene methylation in the processes of aging and tumorigenesis in human liver
    • Choi E.K., Uyeno S., Nishida N., Okumoto T., Fujimura S., Aoki Y., et al. Alterations of c-fos gene methylation in the processes of aging and tumorigenesis in human liver. Mutat Res 1996, 354:123-128.
    • (1996) Mutat Res , vol.354 , pp. 123-128
    • Choi, E.K.1    Uyeno, S.2    Nishida, N.3    Okumoto, T.4    Fujimura, S.5    Aoki, Y.6
  • 42
    • 33747370384 scopus 로고    scopus 로고
    • Multiple roles of FOXO transcription factors in mammalian cells point to multiple roles in cancer
    • Arden K.C. Multiple roles of FOXO transcription factors in mammalian cells point to multiple roles in cancer. Exp Gerontol 2006, 41:709-717.
    • (2006) Exp Gerontol , vol.41 , pp. 709-717
    • Arden, K.C.1
  • 43
    • 32244434160 scopus 로고    scopus 로고
    • P63: a new link between senescence and aging
    • Keyes W.M., Mills A.A. p63: a new link between senescence and aging. Cell Cycle 2006, 5:260-265.
    • (2006) Cell Cycle , vol.5 , pp. 260-265
    • Keyes, W.M.1    Mills, A.A.2
  • 44
    • 49049105552 scopus 로고    scopus 로고
    • Contribution of p53, p63, and p73 to the developmental diseases and cancer
    • Tomkova K., Tomka M., Zajac V. Contribution of p53, p63, and p73 to the developmental diseases and cancer. Neoplasma 2008, 55:177-181.
    • (2008) Neoplasma , vol.55 , pp. 177-181
    • Tomkova, K.1    Tomka, M.2    Zajac, V.3
  • 45
    • 74949122722 scopus 로고    scopus 로고
    • Apolipoprotein D: an overview of its role in aging and age-related diseases
    • Muffat J., Walker D.W. Apolipoprotein D: an overview of its role in aging and age-related diseases. Cell Cycle 2010, 9:269-273.
    • (2010) Cell Cycle , vol.9 , pp. 269-273
    • Muffat, J.1    Walker, D.W.2
  • 46
    • 0142186132 scopus 로고    scopus 로고
    • Insulin/IGF-1 signaling pathway driving aging and cancer as a target for pharmacological intervention
    • Anisimov V.N. Insulin/IGF-1 signaling pathway driving aging and cancer as a target for pharmacological intervention. Exp Gerontol 2003, 38:1041-1049.
    • (2003) Exp Gerontol , vol.38 , pp. 1041-1049
    • Anisimov, V.N.1
  • 47
    • 80054732323 scopus 로고    scopus 로고
    • Chromatin remodeling system, cancer stem-like attractors, and cellular reprogramming
    • Zhang Y., Moriguchi H. Chromatin remodeling system, cancer stem-like attractors, and cellular reprogramming. Cell Mol Life Sci 2011, 68:3557-3571.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 3557-3571
    • Zhang, Y.1    Moriguchi, H.2
  • 48
    • 84861201007 scopus 로고    scopus 로고
    • Immunity, cancer and aging: lessons from mouse models
    • Myers C.E., Mirza N.N., Lustgarten J. Immunity, cancer and aging: lessons from mouse models. Aging Dis 2011, 2:512-523.
    • (2011) Aging Dis , vol.2 , pp. 512-523
    • Myers, C.E.1    Mirza, N.N.2    Lustgarten, J.3
  • 50
    • 71449114145 scopus 로고    scopus 로고
    • Inflammation, aging, and cancer: tumoricidal versus tumorigenesis of immunity: a common denominator mapping chronic diseases
    • Khatami M. Inflammation, aging, and cancer: tumoricidal versus tumorigenesis of immunity: a common denominator mapping chronic diseases. Cell Biochem Biophys 2009, 55:55-79.
    • (2009) Cell Biochem Biophys , vol.55 , pp. 55-79
    • Khatami, M.1
  • 51
    • 70350474789 scopus 로고    scopus 로고
    • Cancer and aging: the molecular pathways
    • Bassi P., Sacco E. Cancer and aging: the molecular pathways. Urol Oncol 2009, 27:620-627.
    • (2009) Urol Oncol , vol.27 , pp. 620-627
    • Bassi, P.1    Sacco, E.2
  • 52
    • 0038049143 scopus 로고    scopus 로고
    • Cancer and ageing: rival demons?
    • Campisi J. Cancer and ageing: rival demons?. Nat Rev Cancer 2003, 3:339-349.
    • (2003) Nat Rev Cancer , vol.3 , pp. 339-349
    • Campisi, J.1
  • 53
    • 34548153747 scopus 로고    scopus 로고
    • How stem cells age and why this makes us grow old
    • Sharpless N.E., DePinho R.A. How stem cells age and why this makes us grow old. Nat Rev Mol Cell Biol 2007, 8:703-713.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 703-713
    • Sharpless, N.E.1    DePinho, R.A.2
  • 54
    • 79958806259 scopus 로고    scopus 로고
    • Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer)
    • Zhang Y. Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer). Gene Regul Syst Biol 2011, 5:1-26.
    • (2011) Gene Regul Syst Biol , vol.5 , pp. 1-26
    • Zhang, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.