Antitumor and anti-metastatic effects of cyclooxygenase-2 inhibition by celecoxib on human colorectal carcinoma xenografts in nude mouse rectum

Oncology Reports

Volumn 28, Issue 3, 2012, Pages 777-784

  Ninomiya, Itasu ^a   Nagai, Noboru ^a   Oyama, Katsunobu ^a   Hayashi, Hironori ^a   Tajima, Hidehiro ^a   Kitagawa, Hirohisa ^a   Fushida, Sachio ^a   Fujimura, Takashi ^a   Ohta, Tetsuo ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Angiogenesis; Apoptosis; Celecoxib; Lung metastasis; Lymph node metastasis; Prostaglandin E 2; Rectal xenograft model

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG SAFETY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; LUNG METASTASIS; LYMPH NODE METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; COLORECTAL NEOPLASMS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DINOPROSTONE; GENE EXPRESSION; HT29 CELLS; HUMANS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; PYRAZOLES; SULFONAMIDES; TUMOR BURDEN; VASCULAR ENDOTHELIAL GROWTH FACTOR A; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84865320862     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1885     Document Type: Article

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