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Volumn 436, Issue 1-2, 2012, Pages 66-74

Double crosslinked interpenetrated network in nanoparticle form for drug targeting - Preparation, characterization and biodistribution studies

Author keywords

Biodistribution; Chitosan; Chloramphenicol; Double crosslinking; Gelatin; Nanoparticles

Indexed keywords

ACETONE; CHITOSAN; CHLORAMPHENICOL; FLUORESCEIN; GELATIN; GLYCINE; NANOPARTICLE; POLYMER; POLYSORBATE 80; SODIUM SULFATE; SORBITAN OLEATE; SURFACTANT; TOLUENE; WATER OIL CREAM;

EID: 84865299188     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.06.029     Document Type: Article
Times cited : (39)

References (52)
  • 2
    • 53849097674 scopus 로고    scopus 로고
    • Development of a smart nano-vehicle to target cerebrovascular amyloid deposits and brain parenchymal plaques observed in Alzheimer's disease and cerebral amyloid angiopathy
    • E.K. Agyare, G.L. Curran, M. Ramakrishnan, C.C. Yu, J.F. Poduslo, and K.K. Kandimalla Development of a smart nano-vehicle to target cerebrovascular amyloid deposits and brain parenchymal plaques observed in Alzheimer's disease and cerebral amyloid angiopathy Pharm. Res. 25 2008 2674 2684
    • (2008) Pharm. Res. , vol.25 , pp. 2674-2684
    • Agyare, E.K.1    Curran, G.L.2    Ramakrishnan, M.3    Yu, C.C.4    Poduslo, J.F.5    Kandimalla, K.K.6
  • 3
    • 0346094228 scopus 로고    scopus 로고
    • Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications
    • J. Berger, M. Reist, J.M. Mayera, O. Felt, N.A. Peppas, and R. Gurny Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications Eur. J. Pharm. Biopharm. 57 2004 19 34
    • (2004) Eur. J. Pharm. Biopharm. , vol.57 , pp. 19-34
    • Berger, J.1    Reist, M.2    Mayera, J.M.3    Felt, O.4    Peppas, N.A.5    Gurny, R.6
  • 4
    • 34548515493 scopus 로고    scopus 로고
    • Double crosslinked polyetheretherketone - Based polymer electrolyte membranes prepared by radiation and thermal crosslinking techniques
    • J. Chen, Y. Maekawa, M. Asano, and M. Yoshida Double crosslinked polyetheretherketone - based polymer electrolyte membranes prepared by radiation and thermal crosslinking techniques Polymer 48 2007 6002 6009
    • (2007) Polymer , vol.48 , pp. 6002-6009
    • Chen, J.1    Maekawa, Y.2    Asano, M.3    Yoshida, M.4
  • 6
    • 40349097794 scopus 로고    scopus 로고
    • Alginate and chitosan particles as drug delivery system for cell therapy
    • G. Ciofani, V. Raffa, A. Menciassi, and P. Dario Alginate and chitosan particles as drug delivery system for cell therapy Biomed. Microdevices 10 2008 131 140
    • (2008) Biomed. Microdevices , vol.10 , pp. 131-140
    • Ciofani, G.1    Raffa, V.2    Menciassi, A.3    Dario, P.4
  • 7
    • 3543046202 scopus 로고    scopus 로고
    • Chitosan nanoparticles as new ocular drug delivery systems: In vitro stability, in vivo fate, and cellular toxicity
    • A.M. De Campos, Y. Diebold, E.L.S. Carvalho, A. Sánchez, and M.J. Alonso Chitosan nanoparticles as new ocular drug delivery systems: in vitro stability, in vivo fate, and cellular toxicity Pharm. Res. 21 2004 803 810
    • (2004) Pharm. Res. , vol.21 , pp. 803-810
    • De Campos, A.M.1    Diebold, Y.2    Carvalho, E.L.S.3    Sánchez, A.4    Alonso, M.J.5
  • 8
    • 17644376482 scopus 로고    scopus 로고
    • Preparation of gelatin microspheres containing lactic acid - Effect of cross-linking on drug release
    • R. Dinarvand, S. Mahmoodi, E. Farboud, M. Salehi, and F. Atyabi Preparation of gelatin microspheres containing lactic acid - effect of cross-linking on drug release Acta Pharm. 55 2005 57 67
    • (2005) Acta Pharm. , vol.55 , pp. 57-67
    • Dinarvand, R.1    Mahmoodi, S.2    Farboud, E.3    Salehi, M.4    Atyabi, F.5
  • 9
    • 0026640760 scopus 로고
    • Chitosan cross-linked with Mo(VI) polyoxyanions: A new gelling system
    • K.I. Draget, K.M. Varum, E. Moen, H. Gynnild, and O. Smidsrod Chitosan cross-linked with Mo(VI) polyoxyanions: a new gelling system Biomaterials 13 1992 635 638
    • (1992) Biomaterials , vol.13 , pp. 635-638
    • Draget, K.I.1    Varum, K.M.2    Moen, E.3    Gynnild, H.4    Smidsrod, O.5
  • 10
    • 77953127556 scopus 로고    scopus 로고
    • Bioadhesive chitosan nanoparticles: Preparation and characterization
    • A.R. Dudhania, and S.L. Kosarajua Bioadhesive chitosan nanoparticles: preparation and characterization Carbohydr. Polym. 81 2010 243 251
    • (2010) Carbohydr. Polym. , vol.81 , pp. 243-251
    • Dudhania, A.R.1    Kosarajua, S.L.2
  • 11
    • 0030271509 scopus 로고    scopus 로고
    • Gelatin microspheres: Influence of preparation parameters and thermal treatment on chemico-physical and biopharmaceutical properties
    • E. Esposito, R. Cortesi, and C. Nastruzzi Gelatin microspheres: influence of preparation parameters and thermal treatment on chemico-physical and biopharmaceutical properties Biomaterials 17 1996 2009 2020
    • (1996) Biomaterials , vol.17 , pp. 2009-2020
    • Esposito, E.1    Cortesi, R.2    Nastruzzi, C.3
  • 12
    • 0035253417 scopus 로고    scopus 로고
    • Effect of cross-linking on the in vitro release kinetics of doxorubicin from gelatin implants
    • H. Fan, and A.K. Dash Effect of cross-linking on the in vitro release kinetics of doxorubicin from gelatin implants Int. J. Pharm. 213 2001 103 116
    • (2001) Int. J. Pharm. , vol.213 , pp. 103-116
    • Fan, H.1    Dash, A.K.2
  • 13
    • 0019562814 scopus 로고
    • Chloramphenicol: A review of its use in clinical practice
    • H.M. Feder Jr.; C. Osier, and E.G. Maderazo Chloramphenicol: a review of its use in clinical practice Rev. Infect. Dis. 3 1981 479 491
    • (1981) Rev. Infect. Dis. , vol.3 , pp. 479-491
    • Feder Jr., H.M.1    Osier, C.2    Maderazo, E.G.3
  • 16
    • 43449112665 scopus 로고    scopus 로고
    • Construction of dermal skeleton by double cross-linking with glutaraldehyde and ultraviolet radiation
    • H. Gu, L. He, L. Liu, and Y.C. Jin Construction of dermal skeleton by double cross-linking with glutaraldehyde and ultraviolet radiation Zhonghua Shao Shang Za Zhi 24 2008 114 117
    • (2008) Zhonghua Shao Shang Za Zhi , vol.24 , pp. 114-117
    • Gu, H.1    He, L.2    Liu, L.3    Jin, Y.C.4
  • 17
    • 77957260032 scopus 로고    scopus 로고
    • Chitosan based delivery systems for mucosal immunization against bovine herpesvirus 1 (BHV-1)
    • M. Günbeyaz, A. Faraji, A. Özkul, N. Pural, and S. Şenel Chitosan based delivery systems for mucosal immunization against bovine herpesvirus 1 (BHV-1) Eur. J. Pharm. Sci. 41 2010 531 545
    • (2010) Eur. J. Pharm. Sci. , vol.41 , pp. 531-545
    • Günbeyaz, M.1    Faraji, A.2    Özkul, A.3    Pural, N.4    Şenel, S.5
  • 18
    • 27644481938 scopus 로고    scopus 로고
    • Porous chitosan-gelatin scaffold containing plasmid DNA encoding transforming growth factor-b1 for chondrocytes proliferation
    • T. Guo, J. Zhao, J. Chang, Z. Ding, H. Hong, J. Chen, and J. Zhang Porous chitosan-gelatin scaffold containing plasmid DNA encoding transforming growth factor-b1 for chondrocytes proliferation Biomaterials 27 2006 1095 1103
    • (2006) Biomaterials , vol.27 , pp. 1095-1103
    • Guo, T.1    Zhao, J.2    Chang, J.3    Ding, Z.4    Hong, H.5    Chen, J.6    Zhang, J.7
  • 19
    • 0037472115 scopus 로고    scopus 로고
    • Chitosan-based gastrointestinal delivery systems
    • R. Hejazi, and M. Amiji Chitosan-based gastrointestinal delivery systems J. Control. Release 89 2003 151 165
    • (2003) J. Control. Release , vol.89 , pp. 151-165
    • Hejazi, R.1    Amiji, M.2
  • 20
    • 23944463701 scopus 로고    scopus 로고
    • In vitro characterization of chitosan-gelatin scaffolds for tissue engineering
    • Y. Huang, S. Onyeri, M. Siewe, A. Moshfeghian, and S.V. Madihally In vitro characterization of chitosan-gelatin scaffolds for tissue engineering Biomaterials 26 2005 7616 7627
    • (2005) Biomaterials , vol.26 , pp. 7616-7627
    • Huang, Y.1    Onyeri, S.2    Siewe, M.3    Moshfeghian, A.4    Madihally, S.V.5
  • 21
    • 79960341942 scopus 로고    scopus 로고
    • Covalent and ionic co-cross-linking - An original way to prepare chitosan-gelatin hydrogels for biomedical applications
    • A.N. Jatariu (Cadinoiu), M. Popa, S. Curteanu, and C.A. Peptu Covalent and ionic co-cross-linking - an original way to prepare chitosan-gelatin hydrogels for biomedical applications J. Biomed. Mater. Res. A 98A 2011 342 350
    • (2011) J. Biomed. Mater. Res. A , vol.98 A , pp. 342-350
    • Jatariu, A.N.1    Popa, M.2    Curteanu, S.3    Peptu, C.A.4
  • 22
    • 0035937593 scopus 로고    scopus 로고
    • Polysaccharide colloidal particles as delivery systems for macromolecules
    • K.A. Janes, P. Calvo, and M.J. Alonso Polysaccharide colloidal particles as delivery systems for macromolecules Adv. Drug Deliv. Rev. 47 2001 83 97
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , pp. 83-97
    • Janes, K.A.1    Calvo, P.2    Alonso, M.J.3
  • 23
    • 77956648913 scopus 로고    scopus 로고
    • Characterization and preparation of core-shell type nanoparticle for encapsulation of anticancer drug
    • M.K. Janga, Y.I. Jeonga, and J.W. Nah Characterization and preparation of core-shell type nanoparticle for encapsulation of anticancer drug Colloids Surf. B 81 2010 530 536
    • (2010) Colloids Surf. B , vol.81 , pp. 530-536
    • Janga, M.K.1    Jeonga, Y.I.2    Nah, J.W.3
  • 24
    • 0024421438 scopus 로고
    • Characteristics of beomycin mitomycin C and 5-fluorouracil from gelatin microspheres
    • R. Jeyanthi, and K. Panduranga-Rao Characteristics of beomycin mitomycin C and 5-fluorouracil from gelatin microspheres Int. J. Pharm. 55 1989 31 37
    • (1989) Int. J. Pharm. , vol.55 , pp. 31-37
    • Jeyanthi, R.1    Panduranga-Rao, K.2
  • 25
    • 76049130071 scopus 로고    scopus 로고
    • Comparison of protein-polysaccharide nanoparticle fabrication methods: Impact of biopolymer complexation before or after particle formation
    • O.G. Jones, E.A. Decker, and D.J. McClements Comparison of protein-polysaccharide nanoparticle fabrication methods: Impact of biopolymer complexation before or after particle formation J. Colloid Interface Sci. 344 2010 21 29
    • (2010) J. Colloid Interface Sci. , vol.344 , pp. 21-29
    • Jones, O.G.1    Decker, E.A.2    McClements, D.J.3
  • 26
    • 0043212012 scopus 로고    scopus 로고
    • Polymeric microspheres for drug delivery to the oral cavity: An in vitro evaluation of mucoadhesive potential
    • S. Kockisch, G.D. Rees, S.A. Young, J. Tsibouklis, and J.D. Smart Polymeric microspheres for drug delivery to the oral cavity: an in vitro evaluation of mucoadhesive potential J. Pharm. Sci. 92 2003 1614 1623
    • (2003) J. Pharm. Sci. , vol.92 , pp. 1614-1623
    • Kockisch, S.1    Rees, G.D.2    Young, S.A.3    Tsibouklis, J.4    Smart, J.D.5
  • 28
    • 67349128618 scopus 로고    scopus 로고
    • Preparation of single or double-network chitosan/poly(vinyl alcohol) gel films through selectively cross-linking method
    • S. Liang, L. Liu, Q. Huang, and K.L. Yam Preparation of single or double-network chitosan/poly(vinyl alcohol) gel films through selectively cross-linking method Carbohydr. Polym. 19 2009 718 724
    • (2009) Carbohydr. Polym. , vol.19 , pp. 718-724
    • Liang, S.1    Liu, L.2    Huang, Q.3    Yam, K.L.4
  • 29
    • 55749108851 scopus 로고    scopus 로고
    • Polysaccharides-based nanoparticles as drug delivery systems
    • Z. Liu, Y. Jiao, Y. Wang, C. Zhou, and Z. Zhang Polysaccharides-based nanoparticles as drug delivery systems Adv. Drug Deliv. Rev. 60 2008 1650 1662
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 1650-1662
    • Liu, Z.1    Jiao, Y.2    Wang, Y.3    Zhou, C.4    Zhang, Z.5
  • 30
    • 77958182219 scopus 로고    scopus 로고
    • Uptake and cytotoxicity of chitosan nanoparticles in human liver cells
    • J.W. Loh, G. Yeoh, M. Saunders, and L.Y. Lim Uptake and cytotoxicity of chitosan nanoparticles in human liver cells Toxicol. Appl. Pharmacol. 249 2010 148 157
    • (2010) Toxicol. Appl. Pharmacol. , vol.249 , pp. 148-157
    • Loh, J.W.1    Yeoh, G.2    Saunders, M.3    Lim, L.Y.4
  • 31
    • 0142183639 scopus 로고    scopus 로고
    • Biodistribution of 131I-BSA loaded gelatin microspheres after peroral application to BALB/c mice - Particle size study
    • K. Mladenovska, E.I. Janevik, M.D. Glavas, E.F. Kumbaradzi, and K. Goracinova Biodistribution of 131I-BSA loaded gelatin microspheres after peroral application to BALB/c mice - particle size study Acta Pharm. 53 2003 187 197
    • (2003) Acta Pharm. , vol.53 , pp. 187-197
    • Mladenovska, K.1    Janevik, E.I.2    Glavas, M.D.3    Kumbaradzi, E.F.4    Goracinova, K.5
  • 33
    • 0032916739 scopus 로고    scopus 로고
    • Biodegradation and distribution of water-soluble chitosan in mice
    • H. Onishi, and Y. Machida Biodegradation and distribution of water-soluble chitosan in mice Biomaterials 20 1999 175 182
    • (1999) Biomaterials , vol.20 , pp. 175-182
    • Onishi, H.1    MacHida, Y.2
  • 34
    • 76149083883 scopus 로고    scopus 로고
    • Double crosslinked chitosan-gelatin particulate systems for ophthalmic applications
    • C.A. Peptu, G. Buhus, M. Popa, A. Perichaud, and D. Costin Double crosslinked chitosan-gelatin particulate systems for ophthalmic applications J. Bioact. Compat. Polym. 25 2010 98 116
    • (2010) J. Bioact. Compat. Polym. , vol.25 , pp. 98-116
    • Peptu, C.A.1    Buhus, G.2    Popa, M.3    Perichaud, A.4    Costin, D.5
  • 35
    • 0031014576 scopus 로고    scopus 로고
    • Use of chitosan as a biomaterial: Studies on its safety and hemostatic potential
    • S.B. Rao, and C.P. Sharma Use of chitosan as a biomaterial: studies on its safety and hemostatic potential J. Biomed. Mater. Res. 34 1997 21 28
    • (1997) J. Biomed. Mater. Res. , vol.34 , pp. 21-28
    • Rao, S.B.1    Sharma, C.P.2
  • 36
    • 0025329096 scopus 로고
    • Albumin microsphere: Effect of process variables on size distribution and in vitro release
    • B.P. Reddy, A.K. Dorle, and D.R. Krishna Albumin microsphere: effect of process variables on size distribution and in vitro release Drug Dev. Ind. Pharm. 16 1990 1791 1803
    • (1990) Drug Dev. Ind. Pharm. , vol.16 , pp. 1791-1803
    • Reddy, B.P.1    Dorle, A.K.2    Krishna, D.R.3
  • 37
    • 0031575556 scopus 로고    scopus 로고
    • Mechanical, water uptake and permeability properties of crosslinked chitosan glutamate and alginate films
    • C. Remunan-Lopez, and R. Bodmeier Mechanical, water uptake and permeability properties of crosslinked chitosan glutamate and alginate films J. Control. Release 44 1997 215 225
    • (1997) J. Control. Release , vol.44 , pp. 215-225
    • Remunan-Lopez, C.1    Bodmeier, R.2
  • 38
    • 34248649305 scopus 로고    scopus 로고
    • Novel interpenetrating polymer network microspheres of chitosan and methylcellulose for controlled release of theophylline
    • A.P. Rokhade, N.B. Shelke, S.A. Patil, and T.M. Aminabhavi Novel interpenetrating polymer network microspheres of chitosan and methylcellulose for controlled release of theophylline Carbohydr. Polym. 69 2007 678 687
    • (2007) Carbohydr. Polym. , vol.69 , pp. 678-687
    • Rokhade, A.P.1    Shelke, N.B.2    Patil, S.A.3    Aminabhavi, T.M.4
  • 39
    • 0034255170 scopus 로고    scopus 로고
    • Characterization of thermosensitive chitosan gels for the sustained delivery of drugs
    • E. Ruel-Gariepy, A. Chenite, C. Chaput, S. Guirguis, and J.C. Leroux Characterization of thermosensitive chitosan gels for the sustained delivery of drugs Int. J. Pharm. 203 2000 89 98
    • (2000) Int. J. Pharm. , vol.203 , pp. 89-98
    • Ruel-Gariepy, E.1    Chenite, A.2    Chaput, C.3    Guirguis, S.4    Leroux, J.C.5
  • 40
    • 0037151324 scopus 로고    scopus 로고
    • Preparation, characterization and in vivo distribution of terbutaline sulfate loaded albumin microspheres
    • S. Sahin, H. Selek, G. Ponchel, and M.T. Ercan Preparation, characterization and in vivo distribution of terbutaline sulfate loaded albumin microspheres J. Control. Release 82 2002 345 358
    • (2002) J. Control. Release , vol.82 , pp. 345-358
    • Sahin, S.1    Selek, H.2    Ponchel, G.3    Ercan, M.T.4
  • 41
    • 0029073777 scopus 로고
    • Controlled release of piroxicam from chitosan beads
    • A.D. Sezer, and J. Akbuga Controlled release of piroxicam from chitosan beads Int. J. Pharm. 121 1995 113 116
    • (1995) Int. J. Pharm. , vol.121 , pp. 113-116
    • Sezer, A.D.1    Akbuga, J.2
  • 43
    • 0035117746 scopus 로고    scopus 로고
    • Chitosan/gelatin microspheres prepared by modified emulsification and ionotropic gelation
    • X.Z. Shu, and K.J. Zhu Chitosan/gelatin microspheres prepared by modified emulsification and ionotropic gelation J. Microencapsul. 18 2001 237 245
    • (2001) J. Microencapsul. , vol.18 , pp. 237-245
    • Shu, X.Z.1    Zhu, K.J.2
  • 44
    • 0024410695 scopus 로고
    • Synthesis of gelatin microspheres containing interferon
    • Y. Tabata, and Y. Ikada Synthesis of gelatin microspheres containing interferon Pharm. Res. 6 1989 422 427
    • (1989) Pharm. Res. , vol.6 , pp. 422-427
    • Tabata, Y.1    Ikada, Y.2
  • 45
    • 78650680356 scopus 로고    scopus 로고
    • Brain targeting with surface-modified poly(d,l-lactic-co-glycolic acid) nanoparticles delivered via carotid artery administration
    • K. Tahara, Y. Miyazaki, Y. Kawashima, J. Kreuter, and H. Yamamoto Brain targeting with surface-modified poly(d,l-lactic-co-glycolic acid) nanoparticles delivered via carotid artery administration Eur. J. Pharm. Biopharm. 77 2011 84 88
    • (2011) Eur. J. Pharm. Biopharm. , vol.77 , pp. 84-88
    • Tahara, K.1    Miyazaki, Y.2    Kawashima, Y.3    Kreuter, J.4    Yamamoto, H.5
  • 46
    • 78049261472 scopus 로고    scopus 로고
    • Production and characterization of chitosan microparticles containing papain for controlled release applications
    • F.C. Vasconcellos, G.A.S. Goulart, and M.M. Beppu Production and characterization of chitosan microparticles containing papain for controlled release applications Powder Technol. 205 2011 65 70
    • (2011) Powder Technol. , vol.205 , pp. 65-70
    • Vasconcellos, F.C.1    Goulart, G.A.S.2    Beppu, M.M.3
  • 47
    • 33745407780 scopus 로고    scopus 로고
    • Preparation and characterization of uniform-sized chitosan microspheres containing insulin by membrane emulsification and a two-step solidification process
    • L.Y. Wang, Y.H. Gu, Q.Z. Zhou, G.H. Ma, Y.H. Wan, and Z.G. Su Preparation and characterization of uniform-sized chitosan microspheres containing insulin by membrane emulsification and a two-step solidification process Colloids Surf. B 50 2006 26 135
    • (2006) Colloids Surf. B , vol.50 , pp. 26-135
    • Wang, L.Y.1    Gu, Y.H.2    Zhou, Q.Z.3    Ma, G.H.4    Wan, Y.H.5    Su, Z.G.6
  • 48
    • 74149094269 scopus 로고    scopus 로고
    • Preparation and evaluation of anti-neuroexcitation peptide (ANEP) loaded N-trimethyl chitosan chloride nanoparticles for brain-targeting
    • S.L. Wang, T.Y. Jiang, M. Ma, Y.C. Hu, and J.H. Zhang Preparation and evaluation of anti-neuroexcitation peptide (ANEP) loaded N-trimethyl chitosan chloride nanoparticles for brain-targeting Int. J. Pharm. 386 2010 249 255
    • (2010) Int. J. Pharm. , vol.386 , pp. 249-255
    • Wang, S.L.1    Jiang, T.Y.2    Ma, M.3    Hu, Y.C.4    Zhang, J.H.5
  • 49
    • 21444461228 scopus 로고    scopus 로고
    • Tricalcium phosphate and glutaraldehyde crosslinked gelatin incorporating bone morphogenetic protein - A viable scaffold for bone tissue engineering
    • S.H. Yang, C.K. Hsu, K.C. Wang, S.M. Hou, and F.H. Lin Tricalcium phosphate and glutaraldehyde crosslinked gelatin incorporating bone morphogenetic protein - a viable scaffold for bone tissue engineering J. Biomed. Mater. Res. B 74 2005 468 475
    • (2005) J. Biomed. Mater. Res. B , vol.74 , pp. 468-475
    • Yang, S.H.1    Hsu, C.K.2    Wang, K.C.3    Hou, S.M.4    Lin, F.H.5
  • 50
    • 0034274955 scopus 로고    scopus 로고
    • Preparation and characterization of hydroxyapatite/chitosan-gelatin network composite
    • Y.J. Yin, F. Zhao, X.F. Song, K.D. Yao, W.W. Lu, and J.C. Leong Preparation and characterization of hydroxyapatite/chitosan-gelatin network composite J. Appl. Polym. Sci. 77 2000 2929 2938
    • (2000) J. Appl. Polym. Sci. , vol.77 , pp. 2929-2938
    • Yin, Y.J.1    Zhao, F.2    Song, X.F.3    Yao, K.D.4    Lu, W.W.5    Leong, J.C.6


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