Preparation and characterization of uniform-sized chitosan microspheres containing insulin by membrane emulsification and a two-step solidification process

Colloids and Surfaces B: Biointerfaces

Volumn 50, Issue 2, 2006, Pages 126-135

  Wang, Lian Yan ^a   Gu, Yong Hong ^b   Zhou, Qing Zhu ^a   Ma, Guang Hui ^a   Wan, Yin Hua ^a   Su, Zhi Guo ^a  

^a INSTITUTE OF PROCESS ENGINEERING   (China)

^b BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

Author keywords

Chitosan microspheres; Glutaraldehyde; Insulin; Membrane emulsification; Tripolyphosphate (TPP); Two step solidification

Indexed keywords

EMULSIFICATION; INSULIN; PERMSELECTIVE MEMBRANES; PH EFFECTS; PROTEINS; SOLIDIFICATION;

CHITOSAN MICROSPHERES; GLUTARALDEHYDE; MEMBRANE EMULSIFICATION; MUCOADHESIVE; TRIPOLYPHOSPHATE (TPP); TWO-STEP SOLIDIFICATION;

POLYSACCHARIDES;

ACETIC ACID; CHITOSAN; EMULSIFYING AGENT; GLUTARALDEHYDE; MICROSPHERE; PARAFFIN; PETROLEUM ETHER; RECOMBINANT HUMAN INSULIN;

AQUEOUS SOLUTION; ARTICLE; CROSS LINKING; DRUG ACTIVITY; DRUG COATING; DRUG RELEASE; IONIC STRENGTH; MICROEMULSION; PARTICLE SIZE; PH MEASUREMENT; POROSITY; PRIORITY JOURNAL; SOLID STATE;

BIOCOMPATIBLE MATERIALS; CHITOSAN; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; EMULSIONS; GLUTARAL; HYDROGEN-ION CONCENTRATION; INSULIN; MATERIALS TESTING; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; POLYPHOSPHATES; WATER;

EID: 33745407780     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2006.05.006     Document Type: Article

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