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Volumn 13, Issue , 2012, Pages

Two glutamic acid residues in the DNA-binding domain are engaged in the release of STAT1 dimers from DNA

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; DNA BINDING PROTEIN; GAMMA INTERFERON; GLUTAMIC ACID; STAT1 PROTEIN; TYROSINE;

EID: 84865296709     PISSN: None     EISSN: 14712121     Source Type: Journal    
DOI: 10.1186/1471-2121-13-22     Document Type: Article
Times cited : (8)

References (48)
  • 1
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • 10.1126/science.277.5332.1630, 9287210
    • Darnell JE. STATs and gene regulation. Science 1997, 277(5332):1630-1635. 10.1126/science.277.5332.1630, 9287210.
    • (1997) Science , vol.277 , Issue.5332 , pp. 1630-1635
    • Darnell, J.E.1
  • 2
    • 52949104437 scopus 로고    scopus 로고
    • Paradigm shifts in the cell biology of STAT signaling
    • 10.1016/j.semcdb.2008.07.003, 2597702, 18691663
    • Sehgal PB. Paradigm shifts in the cell biology of STAT signaling. Semin Cell Dev Biol 2008, 19(4):329-340. 10.1016/j.semcdb.2008.07.003, 2597702, 18691663.
    • (2008) Semin Cell Dev Biol , vol.19 , Issue.4 , pp. 329-340
    • Sehgal, P.B.1
  • 3
    • 0032577678 scopus 로고    scopus 로고
    • Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA
    • 10.1016/S0092-8674(00)81443-9, 9630226
    • Chen X, Vinkemeier U, Zhao Y, Jeruzalmi D, Darnell JE, Kuriyan J. Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA. Cell 1998, 93(5):827-839. 10.1016/S0092-8674(00)81443-9, 9630226.
    • (1998) Cell , vol.93 , Issue.5 , pp. 827-839
    • Chen, X.1    Vinkemeier, U.2    Zhao, Y.3    Jeruzalmi, D.4    Darnell, J.E.5    Kuriyan, J.6
  • 4
    • 0035313701 scopus 로고    scopus 로고
    • The Stat family in cytokine signaling
    • 10.1016/S0955-0674(00)00199-X, 11248555
    • Ihle JN. The Stat family in cytokine signaling. Curr Opin Cell Biol 2001, 13(2):211-217. 10.1016/S0955-0674(00)00199-X, 11248555.
    • (2001) Curr Opin Cell Biol , vol.13 , Issue.2 , pp. 211-217
    • Ihle, J.N.1
  • 5
    • 0036731485 scopus 로고    scopus 로고
    • Stats: Transcriptional control and biological impact
    • Levy DE, Darnell JE. Stats: Transcriptional control and biological impact. Nat Rev Mol Cell Biol 2002, 3(9):651-662.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.9 , pp. 651-662
    • Levy, D.E.1    Darnell, J.E.2
  • 7
    • 0029742102 scopus 로고    scopus 로고
    • Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1
    • 231495, 8756652
    • Shuai K, Liao J, Song MM. Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1. Mol Cell Biol 1996, 16(9):4932-4941. 231495, 8756652.
    • (1996) Mol Cell Biol , vol.16 , Issue.9 , pp. 4932-4941
    • Shuai, K.1    Liao, J.2    Song, M.M.3
  • 8
    • 0029903770 scopus 로고    scopus 로고
    • DNA binding of in vitro activated Stat1α, Stat1β and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites
    • 452306, 8896455
    • Vinkemeier U, Cohen SL, Moarefi I, Chait BT, Kuriyan J, Darnell JE. DNA binding of in vitro activated Stat1α, Stat1β and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites. EMBO J 1996, 15(20):5616-5626. 452306, 8896455.
    • (1996) EMBO J , vol.15 , Issue.20 , pp. 5616-5626
    • Vinkemeier, U.1    Cohen, S.L.2    Moarefi, I.3    Chait, B.T.4    Kuriyan, J.5    Darnell, J.E.6
  • 9
    • 0029739627 scopus 로고    scopus 로고
    • Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain
    • 10.1126/science.273.5276.794, 8670419
    • Xu X, Sun YL, Hoey T. Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain. Science 1996, 273(5276):794-797. 10.1126/science.273.5276.794, 8670419.
    • (1996) Science , vol.273 , Issue.5276 , pp. 794-797
    • Xu, X.1    Sun, Y.L.2    Hoey, T.3
  • 10
    • 2442577024 scopus 로고    scopus 로고
    • A single residue modulates tyrosine dephosphorylation, oligomerization, and nuclear accumulation of Stat transcription factors
    • 10.1074/jbc.M400766200, 15010467
    • Meyer T, Hendry L, Begitt A, John S, Vinkemeier U. A single residue modulates tyrosine dephosphorylation, oligomerization, and nuclear accumulation of Stat transcription factors. J Biol Chem 2004, 279(18):18998-19007. 10.1074/jbc.M400766200, 15010467.
    • (2004) J Biol Chem , vol.279 , Issue.18 , pp. 18998-19007
    • Meyer, T.1    Hendry, L.2    Begitt, A.3    John, S.4    Vinkemeier, U.5
  • 11
    • 0029909271 scopus 로고    scopus 로고
    • Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex
    • 231699, 8943351
    • Horvath CM, Stark GR, Kerr IM, Darnell JE. Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex. Mol Cell Biol 1996, 16(12):6957-6964. 231699, 8943351.
    • (1996) Mol Cell Biol , vol.16 , Issue.12 , pp. 6957-6964
    • Horvath, C.M.1    Stark, G.R.2    Kerr, I.M.3    Darnell, J.E.4
  • 12
    • 0028913109 scopus 로고
    • A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain
    • 10.1101/gad.9.8.984, 7774815
    • Horvath CM, Wen Z, Darnell JE. A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain. Genes Dev 1995, 9(8):984-994. 10.1101/gad.9.8.984, 7774815.
    • (1995) Genes Dev , vol.9 , Issue.8 , pp. 984-994
    • Horvath, C.M.1    Wen, Z.2    Darnell, J.E.3
  • 13
    • 0037134522 scopus 로고    scopus 로고
    • Dissociation time from DNA determines transcriptional function in a STAT1 linker mutant
    • 10.1074/jbc.M112038200, 11834743
    • Yang E, Henriksen MA, Schaefer O, Zakharova N, Darnell JE. Dissociation time from DNA determines transcriptional function in a STAT1 linker mutant. J Biol Chem 2002, 277(16):13455-13462. 10.1074/jbc.M112038200, 11834743.
    • (2002) J Biol Chem , vol.277 , Issue.16 , pp. 13455-13462
    • Yang, E.1    Henriksen, M.A.2    Schaefer, O.3    Zakharova, N.4    Darnell, J.E.5
  • 14
    • 0027493650 scopus 로고
    • A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma
    • 10.1126/science.7690989, 7690989
    • Shuai K, Stark GR, Kerr IM, Darnell JE. A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma. Science 1993, 261(5129):1744-1746. 10.1126/science.7690989, 7690989.
    • (1993) Science , vol.261 , Issue.5129 , pp. 1744-1746
    • Shuai, K.1    Stark, G.R.2    Kerr, I.M.3    Darnell, J.E.4
  • 15
    • 0028349904 scopus 로고
    • Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions
    • 10.1016/0092-8674(94)90357-3, 7510216
    • Shuai K, Horvath CM, Huang LH, Qureshi SA, Cowburn D, Darnell JE. Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions. Cell 1994, 76(5):821-828. 10.1016/0092-8674(94)90357-3, 7510216.
    • (1994) Cell , vol.76 , Issue.5 , pp. 821-828
    • Shuai, K.1    Horvath, C.M.2    Huang, L.H.3    Qureshi, S.A.4    Cowburn, D.5    Darnell, J.E.6
  • 16
    • 0026770248 scopus 로고
    • Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
    • 10.1126/science.1496401, 1496401
    • Schindler C, Shuai K, Prezioso VR, Darnell JE. Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science 1992, 257(5071):809-813. 10.1126/science.1496401, 1496401.
    • (1992) Science , vol.257 , Issue.5071 , pp. 809-813
    • Schindler, C.1    Shuai, K.2    Prezioso, V.R.3    Darnell, J.E.4
  • 17
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • 10.1126/science.8197455, 8197455
    • Darnell JE, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264(5164):1415-1421. 10.1126/science.8197455, 8197455.
    • (1994) Science , vol.264 , Issue.5164 , pp. 1415-1421
    • Darnell, J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 18
    • 0036469065 scopus 로고    scopus 로고
    • Signal transduction and the control of gene expression
    • 10.1126/science.1066355, 11823631
    • Brivanlou AH, Darnell JE. Signal transduction and the control of gene expression. Science 2002, 295(5556):813-818. 10.1126/science.1066355, 11823631.
    • (2002) Science , vol.295 , Issue.5556 , pp. 813-818
    • Brivanlou, A.H.1    Darnell, J.E.2
  • 19
    • 0028979707 scopus 로고
    • Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process
    • 10.1016/1074-7613(95)90012-8, 7796299
    • Greenlund AC, Morales MO, Viviano BL, Yan H, Krolewski J, Schreiber RD. Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process. Immunity 1995, 2(6):677-687. 10.1016/1074-7613(95)90012-8, 7796299.
    • (1995) Immunity , vol.2 , Issue.6 , pp. 677-687
    • Greenlund, A.C.1    Morales, M.O.2    Viviano, B.L.3    Yan, H.4    Krolewski, J.5    Schreiber, R.D.6
  • 20
    • 20144367694 scopus 로고    scopus 로고
    • Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle
    • 10.1073/pnas.0501063102, 554839, 15753310
    • Zhong M, Henriksen MA, Takeuchi K, Schaefer O, Liu B, ten Hoeve J, Ren Z, Mao X, Chen X, Shuai K, Darnell JE. Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle. Proc Natl Acad Sci USA 2005, 102(11):3966-3971. 10.1073/pnas.0501063102, 554839, 15753310.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.11 , pp. 3966-3971
    • Zhong, M.1    Henriksen, M.A.2    Takeuchi, K.3    Schaefer, O.4    Liu, B.5    ten Hoeve, J.6    Ren, Z.7    Mao, X.8    Chen, X.9    Shuai, K.10    Darnell, J.E.11
  • 21
    • 33845718240 scopus 로고    scopus 로고
    • Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain
    • 10.1101/gad.1485406, 1698445, 17182865
    • Mertens C, Zhong M, Krishnaraj R, Zou W, Chen X, Darnell JE. Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain. Genes Dev 2006, 20(24):3372-3381. 10.1101/gad.1485406, 1698445, 17182865.
    • (2006) Genes Dev , vol.20 , Issue.24 , pp. 3372-3381
    • Mertens, C.1    Zhong, M.2    Krishnaraj, R.3    Zou, W.4    Chen, X.5    Darnell, J.E.6
  • 22
    • 48249142418 scopus 로고    scopus 로고
    • Tyrosine phosphorylation regulates the partitioning of STAT1 between different dimer conformations
    • 10.1073/pnas.0802130105, 2453697, 18591661
    • Wenta N, Strauss H, Meyer S, Vinkemeier U. Tyrosine phosphorylation regulates the partitioning of STAT1 between different dimer conformations. Proc Natl Acad Sci USA 2008, 105(27):9238-9243. 10.1073/pnas.0802130105, 2453697, 18591661.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.27 , pp. 9238-9243
    • Wenta, N.1    Strauss, H.2    Meyer, S.3    Vinkemeier, U.4
  • 23
    • 0030670639 scopus 로고    scopus 로고
    • Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1
    • 10.1093/emboj/16.23.7067, 1170309, 9384585
    • Sekimoto T, Imamoto N, Nakajima K, Hirano T, Yoneda Y. Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1. EMBO J 1997, 16(23):7067-7077. 10.1093/emboj/16.23.7067, 1170309, 9384585.
    • (1997) EMBO J , vol.16 , Issue.23 , pp. 7067-7077
    • Sekimoto, T.1    Imamoto, N.2    Nakajima, K.3    Hirano, T.4    Yoneda, Y.5
  • 24
    • 19044367766 scopus 로고    scopus 로고
    • Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin α5
    • 10.1074/jbc.M202943200, 12048190
    • Fagerlund R, Melén K, Kinnunen L, Julkunen I. Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin α5. J Biol Chem 2002, 277(33):30072-30078. 10.1074/jbc.M202943200, 12048190.
    • (2002) J Biol Chem , vol.277 , Issue.33 , pp. 30072-30078
    • Fagerlund, R.1    Melén, K.2    Kinnunen, L.3    Julkunen, I.4
  • 25
    • 0037007207 scopus 로고    scopus 로고
    • Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-α
    • 10.1093/emboj/21.7.1754, 125956, 11927559
    • McBride KM, Banninger G, McDonald C, Reich NC. Regulated nuclear import of the STAT1 transcription factor by direct binding of importin-α. EMBO J 2002, 21(7):1754-1763. 10.1093/emboj/21.7.1754, 125956, 11927559.
    • (2002) EMBO J , vol.21 , Issue.7 , pp. 1754-1763
    • McBride, K.M.1    Banninger, G.2    McDonald, C.3    Reich, N.C.4
  • 26
    • 0041344551 scopus 로고    scopus 로고
    • Importin α nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein
    • 10.1074/jbc.M303571200, 12740372
    • Melén K, Fagerlund R, Franke J, Köhler M, Kinnunen L, Julkunen I. Importin α nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein. J Biol Chem 2003, 278(30):28193-28200. 10.1074/jbc.M303571200, 12740372.
    • (2003) J Biol Chem , vol.278 , Issue.30 , pp. 28193-28200
    • Melén, K.1    Fagerlund, R.2    Franke, J.3    Köhler, M.4    Kinnunen, L.5    Julkunen, I.6
  • 27
    • 77956170743 scopus 로고    scopus 로고
    • Molecular basis for the recognition of phosphorylated STAT1 by importin α5
    • 10.1016/j.jmb.2010.07.013, 2930068, 20643137
    • Nardozzi J, Wenta N, Yasuhara N, Vinkemeier U, Cingolani G. Molecular basis for the recognition of phosphorylated STAT1 by importin α5. J Mol Biol 2010, 402(1):83-100. 10.1016/j.jmb.2010.07.013, 2930068, 20643137.
    • (2010) J Mol Biol , vol.402 , Issue.1 , pp. 83-100
    • Nardozzi, J.1    Wenta, N.2    Yasuhara, N.3    Vinkemeier, U.4    Cingolani, G.5
  • 28
    • 0030936627 scopus 로고    scopus 로고
    • GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression
    • 10.1089/jir.1997.17.121, 9085936
    • Decker T, Kovarik P, Meinke A. GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression. J Interferon Cytokine Res 1997, 17(3):121-134. 10.1089/jir.1997.17.121, 9085936.
    • (1997) J Interferon Cytokine Res , vol.17 , Issue.3 , pp. 121-134
    • Decker, T.1    Kovarik, P.2    Meinke, A.3
  • 29
    • 0035794217 scopus 로고    scopus 로고
    • DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites
    • 10.1074/jbc.M001748200, 11053426
    • Ehret GB, Reichenbach P, Schindler U, Horvath CM, Fritz S, Nabholz M, Bucher P. DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites. J Biol Chem 2001, 276(9):6675-6688. 10.1074/jbc.M001748200, 11053426.
    • (2001) J Biol Chem , vol.276 , Issue.9 , pp. 6675-6688
    • Ehret, G.B.1    Reichenbach, P.2    Schindler, U.3    Horvath, C.M.4    Fritz, S.5    Nabholz, M.6    Bucher, P.7
  • 30
    • 0029972194 scopus 로고    scopus 로고
    • The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase
    • 452449, 8947049
    • Haspel RL, Salditt-Georgieff M, Darnell JE. The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase. EMBO J 1996, 15(22):6262-6268. 452449, 8947049.
    • (1996) EMBO J , vol.15 , Issue.22 , pp. 6262-6268
    • Haspel, R.L.1    Salditt-Georgieff, M.2    Darnell, J.E.3
  • 31
    • 0033621066 scopus 로고    scopus 로고
    • A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1
    • 10.1073/pnas.96.18.10188, 17864, 10468584
    • Haspel RL, Darnell JE. A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1. Proc Natl Acad Sci USA 1999, 96(18):10188-10193. 10.1073/pnas.96.18.10188, 17864, 10468584.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.18 , pp. 10188-10193
    • Haspel, R.L.1    Darnell, J.E.2
  • 32
    • 0036318564 scopus 로고    scopus 로고
    • Identification of a nuclear Stat1 protein tyrosine phosphatase
    • 10.1128/MCB.22.16.5662-5668.2002, 133976, 12138178
    • ten Hoeve J, de Jesus Ibarra-Sanchez M, Fu Y, Zhu W, Tremblay M, David M, Shuai K. Identification of a nuclear Stat1 protein tyrosine phosphatase. Mol Cell Biol 2002, 22(16):5662-5668. 10.1128/MCB.22.16.5662-5668.2002, 133976, 12138178.
    • (2002) Mol Cell Biol , vol.22 , Issue.16 , pp. 5662-5668
    • ten Hoeve, J.1    de Jesus Ibarra-Sanchez, M.2    Fu, Y.3    Zhu, W.4    Tremblay, M.5    David, M.6    Shuai, K.7
  • 33
    • 0036470732 scopus 로고    scopus 로고
    • Constitutive and IFN-γ-induced nuclear import of STAT1 proceed through independent pathways
    • 10.1093/emboj/21.3.344, 125830, 11823427
    • Meyer T, Begitt A, Lödige I, van Rossum M, Vinkemeier U. Constitutive and IFN-γ-induced nuclear import of STAT1 proceed through independent pathways. EMBO J 2002, 21(3):344-354. 10.1093/emboj/21.3.344, 125830, 11823427.
    • (2002) EMBO J , vol.21 , Issue.3 , pp. 344-354
    • Meyer, T.1    Begitt, A.2    Lödige, I.3    van Rossum, M.4    Vinkemeier, U.5
  • 34
    • 0036569411 scopus 로고    scopus 로고
    • Stat5B shuttles between cytoplasm and nucleus in a cytokine-dependent and -independent manner
    • Zeng R, Aoki Y, Yoshida M, Arai K, Watanabe S. Stat5B shuttles between cytoplasm and nucleus in a cytokine-dependent and -independent manner. J Immunol 2002, 168(9):4567-4575.
    • (2002) J Immunol , vol.168 , Issue.9 , pp. 4567-4575
    • Zeng, R.1    Aoki, Y.2    Yoshida, M.3    Arai, K.4    Watanabe, S.5
  • 35
    • 3042552337 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1
    • 10.1083/jcb.200403057, 2172394, 15210729
    • Marg A, Shan Y, Meyer T, Meissner T, Brandenburg M, Vinkemeier U. Nucleocytoplasmic shuttling by nucleoporins Nup153 and Nup214 and CRM1-dependent nuclear export control the subcellular distribution of latent Stat1. J Cell Biol 2004, 165(6):823-833. 10.1083/jcb.200403057, 2172394, 15210729.
    • (2004) J Cell Biol , vol.165 , Issue.6 , pp. 823-833
    • Marg, A.1    Shan, Y.2    Meyer, T.3    Meissner, T.4    Brandenburg, M.5    Vinkemeier, U.6
  • 36
    • 2442504891 scopus 로고    scopus 로고
    • Real time analysis of STAT3 nucleocytoplasmic shuttling
    • 10.1074/jbc.M312530200, 14701810
    • Pranada AL, Metz S, Herrmann A, Heinrich PC, Müller-Newen G. Real time analysis of STAT3 nucleocytoplasmic shuttling. J Biol Chem 2004, 279(15):15114-15123. 10.1074/jbc.M312530200, 14701810.
    • (2004) J Biol Chem , vol.279 , Issue.15 , pp. 15114-15123
    • Pranada, A.L.1    Metz, S.2    Herrmann, A.3    Heinrich, P.C.4    Müller-Newen, G.5
  • 37
    • 0027090310 scopus 로고
    • Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein
    • 10.1126/science.1281555, 1281555
    • Shuai K, Schindler C, Prezioso VR, Darnell JE. Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein. Science 1992, 258(5089):1808-1812. 10.1126/science.1281555, 1281555.
    • (1992) Science , vol.258 , Issue.5089 , pp. 1808-1812
    • Shuai, K.1    Schindler, C.2    Prezioso, V.R.3    Darnell, J.E.4
  • 38
    • 0025083331 scopus 로고
    • Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors
    • 10.1083/jcb.111.3.807, 2116268, 2391365
    • Adam SA, Marr RS, Gerace L. Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. J Cell Biol 1990, 111(3):807-816. 10.1083/jcb.111.3.807, 2116268, 2391365.
    • (1990) J Cell Biol , vol.111 , Issue.3 , pp. 807-816
    • Adam, S.A.1    Marr, R.S.2    Gerace, L.3
  • 39
    • 30044437825 scopus 로고    scopus 로고
    • Nuclear export determines the cytokine sensitivity of STAT transcription factors
    • 10.1074/jbc.M509180200, 16195225
    • Lödige I, Marg A, Wiesner B, Malecová B, Oelgeschläger T, Vinkemeier U. Nuclear export determines the cytokine sensitivity of STAT transcription factors. J Biol Chem 2005, 280(52):43087-43099. 10.1074/jbc.M509180200, 16195225.
    • (2005) J Biol Chem , vol.280 , Issue.52 , pp. 43087-43099
    • Lödige, I.1    Marg, A.2    Wiesner, B.3    Malecová, B.4    Oelgeschläger, T.5    Vinkemeier, U.6
  • 40
    • 0041660942 scopus 로고    scopus 로고
    • DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1
    • 10.1101/gad.268003, 196254, 12923054
    • Meyer T, Marg A, Lemke P, Wiesner B, Vinkemeier U. DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1. Genes Dev 2003, 17(16):1992-2005. 10.1101/gad.268003, 196254, 12923054.
    • (2003) Genes Dev , vol.17 , Issue.16 , pp. 1992-2005
    • Meyer, T.1    Marg, A.2    Lemke, P.3    Wiesner, B.4    Vinkemeier, U.5
  • 41
    • 0040017820 scopus 로고    scopus 로고
    • A functional DNA binding domain is required for growth hormone-induced nuclear accumulation of Stat5B
    • 10.1074/jbc.274.8.5138, 9988763
    • Herrington J, Rui L, Luo G, Yu-Lee LY, Carter-Su C. A functional DNA binding domain is required for growth hormone-induced nuclear accumulation of Stat5B. J Biol Chem 1999, 274(8):5138-5145. 10.1074/jbc.274.8.5138, 9988763.
    • (1999) J Biol Chem , vol.274 , Issue.8 , pp. 5138-5145
    • Herrington, J.1    Rui, L.2    Luo, G.3    Yu-Lee, L.Y.4    Carter-Su, C.5
  • 42
    • 82955206475 scopus 로고    scopus 로고
    • Activated STAT1 transcription factors conduct distinct saltatory movements in the cell nucleus
    • 10.1016/j.bpj.2011.10.006, 22261046
    • Speil J, Baumgart E, Siebrasse JP, Veith R, Vinkemeier U, Kubitscheck U. Activated STAT1 transcription factors conduct distinct saltatory movements in the cell nucleus. Biophys J 2011, 101(11):2592-2600. 10.1016/j.bpj.2011.10.006, 22261046.
    • (2011) Biophys J , vol.101 , Issue.11 , pp. 2592-2600
    • Speil, J.1    Baumgart, E.2    Siebrasse, J.P.3    Veith, R.4    Vinkemeier, U.5    Kubitscheck, U.6
  • 43
    • 0142091544 scopus 로고    scopus 로고
    • STAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the α2-macroglobulin gene
    • 10.1101/gad.1135003, 218150, 14522952
    • Lerner L, Henriksen MA, Zhang X, Darnell JE. STAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the α2-macroglobulin gene. Genes Dev 2003, 17(20):2564-2577. 10.1101/gad.1135003, 218150, 14522952.
    • (2003) Genes Dev , vol.17 , Issue.20 , pp. 2564-2577
    • Lerner, L.1    Henriksen, M.A.2    Zhang, X.3    Darnell, J.E.4
  • 44
    • 0027434082 scopus 로고
    • Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathways
    • 413716, 7693454
    • Müller M, Laxton C, Briscoe J, Schindler C, Improta T, Darnell JE, Stark GR, Kerr IM. Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-α and -γ signal transduction pathways. EMBO J 1993, 12(11):4221-4228. 413716, 7693454.
    • (1993) EMBO J , vol.12 , Issue.11 , pp. 4221-4228
    • Müller, M.1    Laxton, C.2    Briscoe, J.3    Schindler, C.4    Improta, T.5    Darnell, J.E.6    Stark, G.R.7    Kerr, I.M.8
  • 45
    • 0034641751 scopus 로고    scopus 로고
    • Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain
    • 10.1073/pnas.190318397, 27039, 10973496
    • Begitt A, Meyer T, van Rossum M, Vinkemeier U. Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain. Proc Natl Acad Sci USA 2000, 97(19):10418-10423. 10.1073/pnas.190318397, 27039, 10973496.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.19 , pp. 10418-10423
    • Begitt, A.1    Meyer, T.2    van Rossum, M.3    Vinkemeier, U.4
  • 46
    • 0027992051 scopus 로고
    • 12-O-tetradecanoylphorbol-13-acetate- and tumor necrosis factor alpha-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter
    • van de Stolpe A, Caldenhoven E, Stade BG, Koenderman L, Raaijmakers JA, Johnson JP, van der Saag PT. 12-O-tetradecanoylphorbol-13-acetate- and tumor necrosis factor alpha-mediated induction of intercellular adhesion molecule-1 is inhibited by dexamethasone. Functional analysis of the human intercellular adhesion molecular-1 promoter. J Biol Chem 1994, 269(8):6185-6192.
    • (1994) J Biol Chem , vol.269 , Issue.8 , pp. 6185-6192
    • van de Stolpe, A.1    Caldenhoven, E.2    Stade, B.G.3    Koenderman, L.4    Raaijmakers, J.A.5    Johnson, J.P.6    van der Saag, P.T.7
  • 47
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • 10.1016/0092-8674(95)90311-9, 7543024
    • Wen Z, Zhong Z, Darnell JE. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 1995, 82(2):241-250. 10.1016/0092-8674(95)90311-9, 7543024.
    • (1995) Cell , vol.82 , Issue.2 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell, J.E.3
  • 48
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • 10.1093/nar/29.9.e45, 55695, 11328886
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001, 29(9):e45. 10.1093/nar/29.9.e45, 55695, 11328886.
    • (2001) Nucleic Acids Res , vol.29 , Issue.9
    • Pfaffl, M.W.1


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