-
1
-
-
28344456279
-
A Genomic and Functional Inventory of Deubiquitinating Enzymes
-
Nijman SM, Luna-Vargas MP, Velds A, Brummelkamp TR, Dirac AM, et al. (2005) A Genomic and Functional Inventory of Deubiquitinating Enzymes. Cell 123: 773-786.
-
(2005)
Cell
, vol.123
, pp. 773-786
-
-
Nijman, S.M.1
Luna-Vargas, M.P.2
Velds, A.3
Brummelkamp, T.R.4
Dirac, A.M.5
-
3
-
-
68049084674
-
Breaking the Chains: Structure and Function of the Deubiquitinases
-
Komander D, Clague MJ, Urbe S, (2009) Breaking the Chains: Structure and Function of the Deubiquitinases. Nat Rev Mol Cell Biol 10: 550-563.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
4
-
-
67650620318
-
Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
-
Reyes-Turcu FE, Ventii KH, Wilkinson KD, (2009) Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes. Annu Rev Biochem 78: 363-397.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 363-397
-
-
Reyes-Turcu, F.E.1
Ventii, K.H.2
Wilkinson, K.D.3
-
5
-
-
79959906646
-
Balancing Act: Deubiquitinating Enzymes in the Nervous System
-
Todi SV, Paulson HL, (2011) Balancing Act: Deubiquitinating Enzymes in the Nervous System. Trends Neurosci 34: 370-382.
-
(2011)
Trends Neurosci
, vol.34
, pp. 370-382
-
-
Todi, S.V.1
Paulson, H.L.2
-
6
-
-
77949733627
-
Emerging Roles of Deubiquitinases in Cancer-Associated Pathways
-
Sacco JJ, Coulson JM, Clague MJ, Urbe S, (2010) Emerging Roles of Deubiquitinases in Cancer-Associated Pathways. Iubmb Life 62: 140-157.
-
(2010)
Iubmb Life
, vol.62
, pp. 140-157
-
-
Sacco, J.J.1
Coulson, J.M.2
Clague, M.J.3
Urbe, S.4
-
7
-
-
0034327504
-
Ubiquitin in Chains
-
Pickart CM, (2000) Ubiquitin in Chains. Trends Biochem Sci 25: 544-548.
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 544-548
-
-
Pickart, C.M.1
-
8
-
-
8844237615
-
Polyubiquitin Chains: Polymeric Protein Signals
-
Pickart CM, Fushman D, (2004) Polyubiquitin Chains: Polymeric Protein Signals. Curr Opin Chem Biol 8: 610-616.
-
(2004)
Curr Opin Chem Biol
, vol.8
, pp. 610-616
-
-
Pickart, C.M.1
Fushman, D.2
-
9
-
-
79953296816
-
Ubiquitin-Specific Protease 4 Is Inhibited by Its Ubiquitin-Like Domain
-
Luna-Vargas MP, Faesen AC, Van Dijk WJ, Rape M, Fish A, et al. (2011) Ubiquitin-Specific Protease 4 Is Inhibited by Its Ubiquitin-Like Domain. Embo Rep 12: 365-372.
-
(2011)
Embo Rep
, vol.12
, pp. 365-372
-
-
Luna-Vargas, M.P.1
Faesen, A.C.2
van Dijk, W.J.3
Rape, M.4
Fish, A.5
-
10
-
-
81355150892
-
Direct, Noncatalytic Mechanism of Ikk Inhibition by A20
-
Skaug B, Chen J, Du F, He J, Ma A, et al. (2011) Direct, Noncatalytic Mechanism of Ikk Inhibition by A20. Mol Cell 44: 559-571.
-
(2011)
Mol Cell
, vol.44
, pp. 559-571
-
-
Skaug, B.1
Chen, J.2
Du, F.3
He, J.4
Ma, A.5
-
11
-
-
84856415004
-
Positive Regulation of P53 Stability and Activity by the Deubiquitinating Enzyme Otubain 1
-
Sun XX, Challagundla KB, Dai MS, (2012) Positive Regulation of P53 Stability and Activity by the Deubiquitinating Enzyme Otubain 1. Embo J 31: 576-592.
-
(2012)
Embo J
, vol.31
, pp. 576-592
-
-
Sun, X.X.1
Challagundla, K.B.2
Dai, M.S.3
-
12
-
-
0036007417
-
Fat Facets Does a Highwire Act at the Synapse
-
Fischer JA, Overstreet E, (2002) Fat Facets Does a Highwire Act at the Synapse. Bioessays 24: 13-16.
-
(2002)
Bioessays
, vol.24
, pp. 13-16
-
-
Fischer, J.A.1
Overstreet, E.2
-
13
-
-
0027087073
-
The Fat Facets Gene Is Required for Drosophila Eye and Embryo Development
-
Fischer-Vize JA, Rubin GM, Lehmann R, (1992) The Fat Facets Gene Is Required for Drosophila Eye and Embryo Development. Development 116: 985-1000.
-
(1992)
Development
, vol.116
, pp. 985-1000
-
-
Fischer-Vize, J.A.1
Rubin, G.M.2
Lehmann, R.3
-
14
-
-
0023704385
-
The Role of the Otu Gene in Drosophila Oogenesis
-
King RC, Storto PD, (1988) The Role of the Otu Gene in Drosophila Oogenesis. Bioessays 8: 18-24.
-
(1988)
Bioessays
, vol.8
, pp. 18-24
-
-
King, R.C.1
Storto, P.D.2
-
15
-
-
0024368260
-
Sequence and Structure of the Drosophila Melanogaster Ovarian Tumor Gene and Generation of an Antibody Specific for the Ovarian Tumor Protein
-
Steinhauer WR, Walsh RC, Kalfayan LJ, (1989) Sequence and Structure of the Drosophila Melanogaster Ovarian Tumor Gene and Generation of an Antibody Specific for the Ovarian Tumor Protein. Mol Cell Biol 9: 5726-5732.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 5726-5732
-
-
Steinhauer, W.R.1
Walsh, R.C.2
Kalfayan, L.J.3
-
16
-
-
2342449908
-
Hrb27c, Sqd and Otu Cooperatively Regulate Gurken Rna Localization and Mediate Nurse Cell Chromosome Dispersion in Drosophila Oogenesis
-
Goodrich JS, Clouse KN, Schupbach T, (2004) Hrb27c, Sqd and Otu Cooperatively Regulate Gurken Rna Localization and Mediate Nurse Cell Chromosome Dispersion in Drosophila Oogenesis. Development 131: 1949-1958.
-
(2004)
Development
, vol.131
, pp. 1949-1958
-
-
Goodrich, J.S.1
Clouse, K.N.2
Schupbach, T.3
-
17
-
-
34548158011
-
Tumor Suppressor Cyld Regulates Jnk-Induced Cell Death in Drosophila
-
Xue L, Igaki T, Kuranaga E, Kanda H, Miura M, et al. (2007) Tumor Suppressor Cyld Regulates Jnk-Induced Cell Death in Drosophila. Dev Cell 13: 446-454.
-
(2007)
Dev Cell
, vol.13
, pp. 446-454
-
-
Xue, L.1
Igaki, T.2
Kuranaga, E.3
Kanda, H.4
Miura, M.5
-
18
-
-
72649083654
-
The Drosophila Ubiquitin-Specific Protease Dusp36/Scny Targets Imd to Prevent Constitutive Immune Signaling
-
Thevenon D, Engel E, Avet-Rochex A, Gottar M, Bergeret E, et al. (2009) The Drosophila Ubiquitin-Specific Protease Dusp36/Scny Targets Imd to Prevent Constitutive Immune Signaling. Cell Host Microbe 6: 309-320.
-
(2009)
Cell Host Microbe
, vol.6
, pp. 309-320
-
-
Thevenon, D.1
Engel, E.2
Avet-Rochex, A.3
Gottar, M.4
Bergeret, E.5
-
19
-
-
0027160708
-
Targeted Gene Expression As a Means of Altering Cell Fates and Generating Dominant Phenotypes
-
Brand AH, Perrimon N, (1993) Targeted Gene Expression As a Means of Altering Cell Fates and Generating Dominant Phenotypes. Development 118: 401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
20
-
-
0042467554
-
Loss of the Cylindromatosis Tumour Suppressor Inhibits Apoptosis by Activating Nf-Kappab
-
Brummelkamp TR, Nijman SM, Dirac AM, Bernards R, (2003) Loss of the Cylindromatosis Tumour Suppressor Inhibits Apoptosis by Activating Nf-Kappab. Nature 424: 797-801.
-
(2003)
Nature
, vol.424
, pp. 797-801
-
-
Brummelkamp, T.R.1
Nijman, S.M.2
Dirac, A.M.3
Bernards, R.4
-
21
-
-
84857963730
-
An Rna Interference Screen Identifies the Deubiquitinase Stambpl1 as a Critical Regulator of Human T-Cell Leukemia Virus Type 1 Tax Nuclear Export and Nf-Kappab Activation
-
Lavorgna A, Harhaj EW, (2012) An Rna Interference Screen Identifies the Deubiquitinase Stambpl1 as a Critical Regulator of Human T-Cell Leukemia Virus Type 1 Tax Nuclear Export and Nf-Kappab Activation. J Virol 86: 3357-3369.
-
(2012)
J Virol
, vol.86
, pp. 3357-3369
-
-
Lavorgna, A.1
Harhaj, E.W.2
-
22
-
-
33644519040
-
Building Mammalian Signalling Pathways with Rnai Screens
-
Moffat J, Sabatini DM, (2006) Building Mammalian Signalling Pathways with Rnai Screens. Nat Rev Mol Cell Biol 7: 177-187.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 177-187
-
-
Moffat, J.1
Sabatini, D.M.2
-
23
-
-
79958068799
-
An Rnai Screen Identifies Usp2 as a Factor Required for Tnf-Alpha-Induced Nf-Kappab Signaling
-
Metzig M, Nickles D, Falschlehner C, Lehmann-Koch J, Straub BK, et al. (2011) An Rnai Screen Identifies Usp2 as a Factor Required for Tnf-Alpha-Induced Nf-Kappab Signaling. Int J Cancer 129: 607-618.
-
(2011)
Int J Cancer
, vol.129
, pp. 607-618
-
-
Metzig, M.1
Nickles, D.2
Falschlehner, C.3
Lehmann-Koch, J.4
Straub, B.K.5
-
24
-
-
29044448970
-
Nonmuscle Myosin Ii Generates Forces that Transmit Tension and Drive Contraction in Multiple Tissues During Dorsal Closure
-
Franke JD, Montague RA, Kiehart DP, (2005) Nonmuscle Myosin Ii Generates Forces that Transmit Tension and Drive Contraction in Multiple Tissues During Dorsal Closure. Curr Biol 15: 2208-2221.
-
(2005)
Curr Biol
, vol.15
, pp. 2208-2221
-
-
Franke, J.D.1
Montague, R.A.2
Kiehart, D.P.3
-
25
-
-
18944408058
-
Myosin Viia Defects, which Underlie the Usher 1b Syndrome in Humans, Lead to Deafness in Drosophila
-
Todi SV, Franke JD, Kiehart DP, Eberl DF, (2005) Myosin Viia Defects, which Underlie the Usher 1b Syndrome in Humans, Lead to Deafness in Drosophila. Curr Biol 15: 862-868.
-
(2005)
Curr Biol
, vol.15
, pp. 862-868
-
-
Todi, S.V.1
Franke, J.D.2
Kiehart, D.P.3
Eberl, D.F.4
-
26
-
-
50949126350
-
Protein Partners of Deubiquitinating Enzymes
-
Ventii KH, Wilkinson KD, (2008) Protein Partners of Deubiquitinating Enzymes. Biochem J 414: 161-175.
-
(2008)
Biochem J
, vol.414
, pp. 161-175
-
-
Ventii, K.H.1
Wilkinson, K.D.2
-
27
-
-
67649634849
-
Defining the Human Deubiquitinating Enzyme Interaction Landscape
-
Sowa ME, Bennett EJ, Gygi SP, Harper JW, (2009) Defining the Human Deubiquitinating Enzyme Interaction Landscape. Cell 138: 389-403.
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
28
-
-
33847410541
-
Emerging Roles for Ubiquitin and Protein Degradation in Neuronal Function
-
Yi JJ, Ehlers MD, (2007) Emerging Roles for Ubiquitin and Protein Degradation in Neuronal Function. Pharmacol Rev 59: 14-39.
-
(2007)
Pharmacol Rev
, vol.59
, pp. 14-39
-
-
Yi, J.J.1
Ehlers, M.D.2
-
29
-
-
69749110327
-
The Proteasome-Associated Deubiquitinating Enzyme Usp14 Is Essential for the Maintenance of Synaptic Ubiquitin Levels and the Development of Neuromuscular Junctions
-
Chen PC, Qin LN, Li XM, Walters BJ, Wilson JA, et al. (2009) The Proteasome-Associated Deubiquitinating Enzyme Usp14 Is Essential for the Maintenance of Synaptic Ubiquitin Levels and the Development of Neuromuscular Junctions. J Neurosci 29: 10909-10919.
-
(2009)
J Neurosci
, vol.29
, pp. 10909-10919
-
-
Chen, P.C.1
Qin, L.N.2
Li, X.M.3
Walters, B.J.4
Wilson, J.A.5
-
30
-
-
33750935146
-
Transgenic Rescue of Ataxia Mice with Neuronal-Specific Expression of Ubiquitin-Specific Protease 14
-
Crimmins S, Jin Y, Wheeler C, Huffman AK, Chapman C, et al. (2006) Transgenic Rescue of Ataxia Mice with Neuronal-Specific Expression of Ubiquitin-Specific Protease 14. J Neurosci 26: 11423-11431.
-
(2006)
J Neurosci
, vol.26
, pp. 11423-11431
-
-
Crimmins, S.1
Jin, Y.2
Wheeler, C.3
Huffman, A.K.4
Chapman, C.5
-
31
-
-
70349653545
-
The Ataxia (Axj) Mutation Causes Abnormal Gabaa Receptor Turnover in Mice
-
Lappe-Siefke C, Loebrich S, Hevers W, Waidmann OB, Schweizer M, et al. (2009) The Ataxia (Axj) Mutation Causes Abnormal Gabaa Receptor Turnover in Mice. Plos Genet 5: E1000631.
-
(2009)
Plos Genet
, vol.5
-
-
Lappe-Siefke, C.1
Loebrich, S.2
Hevers, W.3
Waidmann, O.B.4
Schweizer, M.5
-
32
-
-
0036842130
-
Synaptic Defects in Ataxia Mice Result from a Mutation in Usp14, Encoding A Ubiquitin-Specific Protease
-
Wilson SM, Bhattacharyya B, Rachel RA, Coppola V, Tessarollo L, et al. (2002) Synaptic Defects in Ataxia Mice Result from a Mutation in Usp14, Encoding A Ubiquitin-Specific Protease. Nat Genet 32: 420-425.
-
(2002)
Nat Genet
, vol.32
, pp. 420-425
-
-
Wilson, S.M.1
Bhattacharyya, B.2
Rachel, R.A.3
Coppola, V.4
Tessarollo, L.5
-
33
-
-
0035476459
-
Peripheral Glia Direct Axon Guidance across the Cns/Pns Transition Zone
-
Sepp KJ, Schulte J, Auld VJ, (2001) Peripheral Glia Direct Axon Guidance across the Cns/Pns Transition Zone. Dev Biol 238: 47-63.
-
(2001)
Dev Biol
, vol.238
, pp. 47-63
-
-
Sepp, K.J.1
Schulte, J.2
Auld, V.J.3
-
34
-
-
77954903507
-
Balanced Ubiquitylation and Deubiquitylation of Frizzled Regulate Cellular Responsiveness to Wg/Wnt
-
Mukai A, Yamamoto-Hino M, Awano W, Watanabe W, Komada M, et al. (2010) Balanced Ubiquitylation and Deubiquitylation of Frizzled Regulate Cellular Responsiveness to Wg/Wnt. Embo J 29: 2114-2125.
-
(2010)
Embo J
, vol.29
, pp. 2114-2125
-
-
Mukai, A.1
Yamamoto-Hino, M.2
Awano, W.3
Watanabe, W.4
Komada, M.5
-
35
-
-
80051745465
-
Ube2w and Ataxin-3 Coordinately Regulate the Ubiquitin Ligase Chip
-
Scaglione KM, Zavodszky E, Todi SV, Patury S, Xu P, et al. (2011) Ube2w and Ataxin-3 Coordinately Regulate the Ubiquitin Ligase Chip. Mol Cell 43: 599-612.
-
(2011)
Mol Cell
, vol.43
, pp. 599-612
-
-
Scaglione, K.M.1
Zavodszky, E.2
Todi, S.V.3
Patury, S.4
Xu, P.5
-
36
-
-
34548410374
-
Inactivation of the Mouse Atxn3 (Ataxin-3) Gene Increases Protein Ubiquitination
-
Schmitt I, Linden M, Khazneh H, Evert BO, Breuer P, et al. (2007) Inactivation of the Mouse Atxn3 (Ataxin-3) Gene Increases Protein Ubiquitination. Biochem Biophys Res Commun 362: 734-739.
-
(2007)
Biochem Biophys Res Commun
, vol.362
, pp. 734-739
-
-
Schmitt, I.1
Linden, M.2
Khazneh, H.3
Evert, B.O.4
Breuer, P.5
-
37
-
-
55549086868
-
The Deubiquitinating Enzyme Ataxin-3, A Polyglutamine Disease Protein, Edits K63-Linkages in Mixed Linkage Ubiquitin Chains
-
Winborn BJ, Travis SM, Todi SV, Scaglione KM, Xu P, et al. (2008) The Deubiquitinating Enzyme Ataxin-3, A Polyglutamine Disease Protein, Edits K63-Linkages in Mixed Linkage Ubiquitin Chains. J Biol Chem 283: 26436-26443.
-
(2008)
J Biol Chem
, vol.283
, pp. 26436-26443
-
-
Winborn, B.J.1
Travis, S.M.2
Todi, S.V.3
Scaglione, K.M.4
Xu, P.5
-
38
-
-
84857563430
-
Deubiquitylating Enzyme Usp2 Counteracts Nedd4-2-Mediated Downregulation of Kcnq1 Potassium Channels
-
Krzystanek K, Rasmussen HB, Grunnet M, Staub O, Olesen SP, et al. (2012) Deubiquitylating Enzyme Usp2 Counteracts Nedd4-2-Mediated Downregulation of Kcnq1 Potassium Channels. Heart Rhythm 9: 440-448.
-
(2012)
Heart Rhythm
, vol.9
, pp. 440-448
-
-
Krzystanek, K.1
Rasmussen, H.B.2
Grunnet, M.3
Staub, O.4
Olesen, S.P.5
-
39
-
-
84859602197
-
De-Ubiquitinating Protease Usp2a Targets Rip1 and Traf2 to Mediate Cell Death by Tnf
-
Mahul-Mellier AL, Pazarentzos E, Datler C, Iwasawa R, Abuali G, et al. (2012) De-Ubiquitinating Protease Usp2a Targets Rip1 and Traf2 to Mediate Cell Death by Tnf. Cell Death Differ 19: 891-899.
-
(2012)
Cell Death Differ
, vol.19
, pp. 891-899
-
-
Mahul-Mellier, A.L.1
Pazarentzos, E.2
Datler, C.3
Iwasawa, R.4
Abuali, G.5
-
40
-
-
80052049291
-
Ubiquitin-Specific Peptidase 20 Targets Traf6 and Human T Cell Leukemia Virus Type 1 Tax to Negatively Regulate Nf-Kappab Signaling
-
Yasunaga J, Lin FC, Lu X, Jeang KT, (2011) Ubiquitin-Specific Peptidase 20 Targets Traf6 and Human T Cell Leukemia Virus Type 1 Tax to Negatively Regulate Nf-Kappab Signaling. J Virol 85: 6212-6219.
-
(2011)
J Virol
, vol.85
, pp. 6212-6219
-
-
Yasunaga, J.1
Lin, F.C.2
Lu, X.3
Jeang, K.T.4
-
41
-
-
79956128376
-
The Ubiquitin-Specific Protease Usp34 Regulates Axin Stability and Wnt/Beta-Catenin Signaling
-
Lui TT, Lacroix C, Ahmed SM, Goldenberg SJ, Leach CA, et al. (2011) The Ubiquitin-Specific Protease Usp34 Regulates Axin Stability and Wnt/Beta-Catenin Signaling. Mol Cell Biol 31: 2053-2065.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 2053-2065
-
-
Lui, T.T.1
Lacroix, C.2
Ahmed, S.M.3
Goldenberg, S.J.4
Leach, C.A.5
-
42
-
-
0032829026
-
A Direct Screen Identifies New Flight Muscle Mutants on the Drosophila Second Chromosome
-
Nongthomba U, Ramachandra NB, (1999) A Direct Screen Identifies New Flight Muscle Mutants on the Drosophila Second Chromosome. Genetics 153: 261-274.
-
(1999)
Genetics
, vol.153
, pp. 261-274
-
-
Nongthomba, U.1
Ramachandra, N.B.2
-
43
-
-
78650694150
-
Reduction of Protein Translation and Activation of Autophagy Protect Against Pink1 Pathogenesis in Drosophila Melanogaster
-
Liu S, Lu B, (2010) Reduction of Protein Translation and Activation of Autophagy Protect Against Pink1 Pathogenesis in Drosophila Melanogaster. Plos Genet 6: E1001237.
-
(2010)
Plos Genet
, vol.6
-
-
Liu, S.1
Lu, B.2
-
44
-
-
77955927839
-
Nonmuscle Myosin Ii Is Required for Cell Proliferation, Cell Sheet Adhesion and Wing Hair Morphology during Wing Morphogenesis
-
Franke JD, Montague RA, Kiehart DP, (2010) Nonmuscle Myosin Ii Is Required for Cell Proliferation, Cell Sheet Adhesion and Wing Hair Morphology during Wing Morphogenesis. Dev Biol 345: 117-132.
-
(2010)
Dev Biol
, vol.345
, pp. 117-132
-
-
Franke, J.D.1
Montague, R.A.2
Kiehart, D.P.3
-
45
-
-
60549100850
-
Ubiquitination Directly Enhances Activity of the Deubiquitinating Enzyme Ataxin-3
-
Todi SV, Winborn BJ, Scaglione KM, Blount JR, Travis SM, et al. (2009) Ubiquitination Directly Enhances Activity of the Deubiquitinating Enzyme Ataxin-3. Embo J 28: 372-382.
-
(2009)
Embo J
, vol.28
, pp. 372-382
-
-
Todi, S.V.1
Winborn, B.J.2
Scaglione, K.M.3
Blount, J.R.4
Travis, S.M.5
|