Molecular mechanism of the allosteric enhancement of the umami taste sensation

FEBS Journal

Volumn 279, Issue 17, 2012, Pages 3112-3120

  Mouritsen, Ole G ^a   Khandelia, Himanshu ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

allosteric mechanism; GPCR; molecular dynamics; T1R1 T1R3; umami taste receptor

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GLUTAMIC ACID; GUANOSINE PHOSPHATE; PROTEIN T1R1; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; ORGANOLEPTIC PROPERTY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STABILITY; RECEPTOR BINDING; SIGNAL TRANSDUCTION; UMAMI TASTE; VENUS FLYTRAP DOMAIN;

5'-GUANYLIC ACID; ALLOSTERIC REGULATION; GLUTAMIC ACID; MODELS, MOLECULAR; PRINCIPAL COMPONENT ANALYSIS; PROTEIN CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; TASTE;

DIONAEA;

EID: 84865234816     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2012.08690.x     Document Type: Article

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