메뉴 건너뛰기




Volumn 9, Issue 3, 2012, Pages 207-213

Short-term high-dose effect of lovastatin on thrombolysis by rt-PA in a human whole-blood in vitro clot model

Author keywords

Acute Ischemic Stroke; Human blood clot model; Lovastatin; Neuroprotection; rt PA; Thrombolysis

Indexed keywords

ALCOHOL; ALTEPLASE; DRUG METABOLITE; FRESH FROZEN PLASMA; LOVASTATIN HYDROXY ACID; MEVINOLIN; UNCLASSIFIED DRUG;

EID: 84865230660     PISSN: 15672026     EISSN: 18755739     Source Type: Journal    
DOI: 10.2174/156720212801619054     Document Type: Article
Times cited : (3)

References (68)
  • 1
    • 7644242146 scopus 로고    scopus 로고
    • Effects of statins on endothelium and signaling mechanisms
    • DOI 10.1161/01.STR.0000143319.73503.38
    • Endres M, Laufs U. Effects of statins on endothelium and signaling mechanisms. Stroke 2004; 35:2708-11. (Pubitemid 39458376)
    • (2004) Stroke , vol.35 , Issue.11 SUPPL. 1 , pp. 2708-2711
    • Endres, M.1    Laufs, U.2
  • 2
    • 30644478973 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors (statins) as anticancer drugs (review)
    • Fritz G. HMG-CoA reductase inhibitors (statins) as anticancer drugs (review). Int J Oncol 2005; 27:1401-9.
    • (2005) Int J Oncol , vol.27 , pp. 1401-1409
    • Fritz, G.1
  • 4
    • 77952283936 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor lovastatin upregulates plasminogen activator production through RhoAsignaling in peritoneal cell line Met5A
    • Suzuki N, Imai A. HMG-CoA reductase inhibitor lovastatin upregulates plasminogen activator production through RhoAsignaling in peritoneal cell line Met5A. Gynecol Surg 2010;7:189-93.
    • (2010) Gynecol Surg , vol.7 , pp. 189-193
    • Suzuki, N.1    Imai, A.2
  • 5
    • 0031881755 scopus 로고    scopus 로고
    • Hydrophilicity/Lipophilicity: Relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors
    • DOI 10.1016/S0165-6147(97)01147-4
    • B.A. Hamelin, Turgeon J. Hydrophilicity/ lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors. Trends Pharmacol Sci 1998; 19(1):26-37. (Pubitemid 28094090)
    • (1998) Trends in Pharmacological Sciences , vol.19 , Issue.1 , pp. 26-37
    • Hamelin, B.A.1    Turgeon, J.2
  • 7
    • 0028779912 scopus 로고
    • Scandinavian simvastatin study (4S)
    • Stalenhoef AF. Scandinavian simvastatin study (4S). Lancet 1994; 344:8939-40.
    • (1994) Lancet , vol.344 , pp. 8939-8940
    • Stalenhoef, A.F.1
  • 8
    • 79954581852 scopus 로고    scopus 로고
    • Association between acute statin therapy, survival, and improved functional outcome after ischemic stroke the north dublin population stroke study
    • Chróinin DN, Callaly EL, Duggan J, et al. Association between acute statin therapy, survival, and improved functional outcome after ischemic stroke the north dublin population stroke study. Stroke 2011; 42:1021-9.
    • (2011) Stroke , vol.42 , pp. 1021-1029
    • Chróinin, D.N.1    Callaly, E.L.2    Duggan, J.3
  • 9
    • 22544457919 scopus 로고    scopus 로고
    • Lipid-lowering agent use at ischemic stroke onset is associated with decreased mortality
    • DOI 10.1212/01.WNL.0000171746.63844.6a
    • Elkind M, Flint A, Sciacca R, et al. Lipid-lowering agent use at ischemic stroke onset is associated with decreased mortality. Neurology 2005; 65:253-8. (Pubitemid 41022370)
    • (2005) Neurology , vol.65 , Issue.2 , pp. 253-258
    • Elkind, M.S.V.1    Flint, A.C.2    Sciacca, R.R.3    Sacco, R.L.4
  • 10
    • 79955918190 scopus 로고    scopus 로고
    • High-dose atorvastatin and risk of atrial fibrillation in patients with prior stroke or transient ischemic attack: Analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial
    • Schwartz GG, Chaitman BR, Goldberger JJ, et al. High-dose atorvastatin and risk of atrial fibrillation in patients with prior stroke or transient ischemic attack: Analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Am Heart J 2011; 161(5):993-9.
    • (2011) Am Heart J , vol.161 , Issue.5 , pp. 993-999
    • Schwartz, G.G.1    Chaitman, B.R.2    Goldberger, J.J.3
  • 11
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterollowering treatment: Prospective meta-analysis of data from 90, 056 participants in 14 randomised trials of statins
    • Cholesterol Treatment Trialists' (CTT) Collaborators
    • Baigent C, Keech A, Kearney PM, et al. Cholesterol Treatment Trialists' (CTT) Collaborators. Efficacy and safety of cholesterollowering treatment: prospective meta-analysis of data from 90, 056 participants in 14 randomised trials of statins. Lancet 2005; 366(9493):1267-78.
    • (2005) Lancet , vol.366 , Issue.9493 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3
  • 12
    • 33746895436 scopus 로고    scopus 로고
    • High-dose atorvastatin after stroke or transient ischemic attack
    • The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators
    • The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators. High-dose atorvastatin after stroke or transient ischemic attack. New Engl J Med 2006; 355(6):549-59.
    • (2006) New Engl J Med , vol.355 , Issue.6 , pp. 549-559
  • 14
    • 62649086172 scopus 로고    scopus 로고
    • The pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodulation and thrombogenesis
    • Blum A, Shamburek R. The pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodulation and thrombogenesis. Atherosclerosis 2009; 203(2):325-30.
    • (2009) Atherosclerosis , vol.203 , Issue.2 , pp. 325-330
    • Blum, A.1    Shamburek, R.2
  • 15
    • 78651385719 scopus 로고    scopus 로고
    • Statins and stroke: Prevention and beyond
    • Prinz V, Endres M. Statins and stroke: Prevention and beyond. Curr Opin Neurol 2011; 24(1):75-80.
    • (2011) Curr Opin Neurol , vol.24 , Issue.1 , pp. 75-80
    • Prinz, V.1    Endres, M.2
  • 17
    • 2942720515 scopus 로고    scopus 로고
    • Beneficial cardiovascular pleiotropic effects of statins
    • Davignon J. Beneficial cardiovascular pleiotropic effects of statins. Circulation 2004;109(23 suppl 1):III-39-43. (Pubitemid 38786442)
    • (2004) Circulation , vol.109 , Issue.SUPPL.23
    • Davignon, J.1
  • 19
    • 84855344320 scopus 로고    scopus 로고
    • Statin use during ischemic stroke hospitalization is strongly associated with improved poststroke survival
    • Flint AC, Kamel H, Navi BB, et al. Statin use during ischemic stroke hospitalization is strongly associated with improved poststroke survival. Stroke 2012; 43(1):147-54.
    • (2012) Stroke , vol.43 , Issue.1 , pp. 147-154
    • Flint, A.C.1    Kamel, H.2    Navi, B.B.3
  • 20
    • 79955479915 scopus 로고    scopus 로고
    • Preexisting statin use is associated with greater reperfusion in hyperacute ischemic stroke
    • Ford AL, An H, D'Angelo G, et al. Preexisting statin use is associated with greater reperfusion in hyperacute ischemic stroke. Stroke 2011; 42(5):1307-13.
    • (2011) Stroke , vol.42 , Issue.5 , pp. 1307-1313
    • Ford, A.L.1    An, H.2    D'Angelo, G.3
  • 21
    • 77955269145 scopus 로고    scopus 로고
    • Incidence of perioperative myocardial infarction and of 2-year mortality in 577 elderly patients undergoing noncardiac vascular surgery treated with and without statins
    • Desai H, Aronow WS, Ahn C, et al. Incidence of perioperative myocardial infarction and of 2-year mortality in 577 elderly patients undergoing noncardiac vascular surgery treated with and without statins. Arch Gerontol Geriatrics 2010; 51(2):149-51.
    • (2010) Arch Gerontol Geriatrics , vol.51 , Issue.2 , pp. 149-151
    • Desai, H.1    Aronow, W.S.2    Ahn, C.3
  • 22
    • 84857791667 scopus 로고    scopus 로고
    • Beneficial effects of statin treatment on coronary microvascular dysfunction and left ventricular remodeling in patients with acute myocardial infarction
    • Ishida K, Geshi T, Nakano A, et al. Beneficial effects of statin treatment on coronary microvascular dysfunction and left ventricular remodeling in patients with acute myocardial infarction. Int J Cardiol 2012; 155(3):442-7.
    • (2012) Int J Cardiol , vol.155 , Issue.3 , pp. 442-447
    • Ishida, K.1    Geshi, T.2    Nakano, A.3
  • 23
    • 77949869985 scopus 로고    scopus 로고
    • Atherosclerosis induced by chronic inhibition of the synthesis of nitric oxide in moderately hypercholesterolaemic rabbits is suppressed by pitavastatin
    • Kitahara M, Kanaki T, Ishii I, et al. Atherosclerosis induced by chronic inhibition of the synthesis of nitric oxide in moderately hypercholesterolaemic rabbits is suppressed by pitavastatin. Brit J Pharmacol 2010; 159(7):1418-28.
    • (2010) Brit J Pharmacol , vol.159 , Issue.7 , pp. 1418-1428
    • Kitahara, M.1    Kanaki, T.2    Ishii, I.3
  • 24
    • 84055182538 scopus 로고    scopus 로고
    • Myocardial redox state predicts in-hospital clinical outcome after cardiac surgery: Effects of short-term pre-operative statin treatment
    • Antoniades C, Demosthenous M, Reilly S, et al. Myocardial redox state predicts in-hospital clinical outcome after cardiac surgery: Effects of short-term pre-operative statin treatment. J Am Coll Cardiol 2012; 59(1):60-70.
    • (2012) J Am Coll Cardiol , vol.59 , Issue.1 , pp. 60-70
    • Antoniades, C.1    Demosthenous, M.2    Reilly, S.3
  • 27
    • 77951667101 scopus 로고    scopus 로고
    • Prior simvastatin treatment is associated with reduced thrombin generation and platelet activation in patients with acute ST-segment elevation myocardial infarction
    • Pastuszczak M, Kotlarz A, Mostowik M, et al. Prior simvastatin treatment is associated with reduced thrombin generation and platelet activation in patients with acute ST-segment elevation myocardial infarction. Thromb Res 2010; 125(5):382-6.
    • (2010) Thromb Res , vol.125 , Issue.5 , pp. 382-386
    • Pastuszczak, M.1    Kotlarz, A.2    Mostowik, M.3
  • 28
    • 0035826856 scopus 로고    scopus 로고
    • Simvastatin depresses blood clotting by inhibiting activation of prothrombin, factor V, and factor XIII and by enhancing factor Va inactivation
    • Undas A, Brummel KE, Musial J, et al. Simvastatin depresses blood clotting by inhibiting activation of prothrombin, factor V, and factor XIII and by enhancing factor Va inactivation. Circulation 2001; 103(18):2248-53. (Pubitemid 32433713)
    • (2001) Circulation , vol.103 , Issue.18 , pp. 2248-2253
    • Undas, A.1    Brummel, K.E.2    Musial, J.3    Mann, K.G.4    Szczeklik, A.5
  • 29
    • 33749639810 scopus 로고    scopus 로고
    • Statins as acute-stroke treatment
    • DOI 10.1111/j.1747-4949.2006.00061.x
    • Elkind MSV. Statins as acute-stroke treatment. Int J Stroke 2006; 1(4):224-5. (Pubitemid 44541736)
    • (2006) International Journal of Stroke , vol.1 , Issue.4 , pp. 224-225
    • Elkind, M.S.V.1
  • 30
    • 67651174743 scopus 로고    scopus 로고
    • Simvastatin attenuates microglia, astrocyte activation and decreases IL-1β level following traumatic brain injury
    • Li B, Mahmood A, Lu D, et al. Simvastatin attenuates microglia, astrocyte activation and decreases IL-1β level following traumatic brain injury. Neurosurgery 2009; 65(1):179-86.
    • (2009) Neurosurgery , vol.65 , Issue.1 , pp. 179-186
    • Li, B.1    Mahmood, A.2    Lu, D.3
  • 31
    • 79953677834 scopus 로고    scopus 로고
    • Vascular recovery promoted by atorvastatin and simvastatin after experimental intracerebral hemorrhage: Magnetic resonance imaging and histological study: Laboratory investigation
    • Yang D, Knight RA, Han Y, et al. Vascular recovery promoted by atorvastatin and simvastatin after experimental intracerebral hemorrhage: Magnetic resonance imaging and histological study: Laboratory investigation. J Neurosurg 2011; 114(4):1135-42.
    • (2011) J Neurosurg , vol.114 , Issue.4 , pp. 1135-1142
    • Yang, D.1    Knight, R.A.2    Han, Y.3
  • 32
    • 77956410517 scopus 로고    scopus 로고
    • Comparison of the post-embolization effects of tissue-plasminogen activator and simvastatin on neurological outcome in a clinically relevant rat model of acute ischemic stroke
    • Guluma KZ, Lapchak PA. Comparison of the post-embolization effects of tissue-plasminogen activator and simvastatin on neurological outcome in a clinically relevant rat model of acute ischemic stroke. Brain Res 2010; 1354:206-16.
    • (2010) Brain Res , vol.1354 , pp. 206-216
    • Guluma, K.Z.1    Lapchak, P.A.2
  • 33
    • 72049117774 scopus 로고    scopus 로고
    • The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor simvastatin reduces thrombolytic-induced intracerebral hemorrhage in embolized rabbits
    • Lapchak PA, Han MK. The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor simvastatin reduces thrombolytic-induced intracerebral hemorrhage in embolized rabbits. Brain Res 2009;1303(0):144-50.
    • (2009) Brain Res , vol.1303 , Issue.0 , pp. 144-150
    • Lapchak, P.A.1    Han, M.K.2
  • 34
    • 77954083281 scopus 로고    scopus 로고
    • Simvastatin improves clinical scores in a rabbit multiple infarct ischemic stroke model: Synergism with a ROCK inhibitor but not the thrombolytic tissue plasminogen activator
    • Lapchak PA, Han MK. Simvastatin improves clinical scores in a rabbit multiple infarct ischemic stroke model: Synergism with a ROCK inhibitor but not the thrombolytic tissue plasminogen activator. Brain Res 2010; 1344(0):217-25.
    • (2010) Brain Res , vol.1344 , Issue.0 , pp. 217-225
    • Lapchak, P.A.1    Han, M.K.2
  • 36
    • 0031438501 scopus 로고    scopus 로고
    • Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages
    • Pahan K, Sheikh FG, Namboodiri AM, et al. Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J Clin Invest 1997; 100(11):2671-9. (Pubitemid 28007534)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.11 , pp. 2671-2679
    • Pahan, K.1    Sheikh, F.G.2    Namboodiri, M.S.3    Singh, I.4
  • 37
    • 71949090905 scopus 로고    scopus 로고
    • Atorvastatin extends the therapeutic window for tPA to 6 h after the onset of embolic stroke in rats
    • Zhang L, Chopp M, Jia L, et al. Atorvastatin extends the therapeutic window for tPA to 6 h after the onset of embolic stroke in rats. J Cereb Blood Flow Metab 2009; 29(11):1816-24.
    • (2009) J Cereb Blood Flow Metab , vol.29 , Issue.11 , pp. 1816-1824
    • Zhang, L.1    Chopp, M.2    Jia, L.3
  • 38
    • 0037319355 scopus 로고    scopus 로고
    • Withdrawal of statin treatment abrogates stroke protection in mice
    • DOI 10.1161/01.STR.0000054055.28435.BF
    • Gertz K, Laufs U, Lindauer U, et al. Withdrawal of statin treatment abrogates stroke protection in mice. Stroke 2003; 34(2):551-7. (Pubitemid 36206363)
    • (2003) Stroke , vol.34 , Issue.2 , pp. 551-557
    • Gertz, K.1    Laufs, U.2    Lindauer, U.3    Nickenig, G.4    Bohm, M.5    Dirnagl, U.6    Endres, M.7
  • 39
    • 67650492245 scopus 로고    scopus 로고
    • High-dose lovastatin for acute ischemic stroke: Results of the phase i dose escalation neuroprotection with statin therapy for acute recovery trial (NeuSTART)
    • Elkind MSV, Sacco RL, MacArthur RB, et al. High-dose lovastatin for acute ischemic stroke: Results of the phase I dose escalation neuroprotection with statin therapy for acute recovery trial (NeuSTART). Cerebrovascular Dis 2009; 28(3):266-75.
    • (2009) Cerebrovascular Dis , vol.28 , Issue.3 , pp. 266-275
    • Elkind, M.S.V.1    Sacco, R.L.2    MacArthur, R.B.3
  • 41
    • 80053353330 scopus 로고    scopus 로고
    • Novel mechanistic and clinical implications concerning the safety of statin discontinuation
    • Jasińska-Stroschein M, Owczarek J, Wejman I, et al. Novel mechanistic and clinical implications concerning the safety of statin discontinuation. Pharmacol Rep 2011; 63(4):867-79.
    • (2011) Pharmacol Rep , vol.63 , Issue.4 , pp. 867-879
    • Jasińska-Stroschein, M.1    Owczarek, J.2    Wejman, I.3
  • 42
    • 0033811975 scopus 로고    scopus 로고
    • Effect of atorvastatin and fluvastatin on the expression of plasminogen activator inhibitor type-1 in cultured human endothelial cells
    • Lopez S, Peiretti F, Bonardo B, et al. Effect of atorvastatin and fluvastatin on the expression of plasminogen activator inhibitor type-1 in cultured human endothelial cells. Atherosclerosis 2000; 152(2):359-66.
    • (2000) Atherosclerosis , vol.152 , Issue.2 , pp. 359-366
    • Lopez, S.1    Peiretti, F.2    Bonardo, B.3
  • 43
    • 0032487342 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells: Role of geranylgeranylation and Rho proteins
    • Essig M, Nguyen G, Priè D, et al. 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells: Role of geranylgeranylation and rho proteins. Circ Res 1998; 83(7):683-90. (Pubitemid 28462781)
    • (1998) Circulation Research , vol.83 , Issue.7 , pp. 683-690
    • Essig, M.1    Nguyen, G.2    Prie, D.3    Escoubet, B.4    Sraer, J.-D.5    Friedlander, G.6
  • 44
    • 0033800718 scopus 로고    scopus 로고
    • Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice
    • Laufs U, Gertz K, Huang P, et al. Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice. Stroke 2000; 31:2442-9.
    • (2000) Stroke , vol.31 , pp. 2442-2449
    • Laufs, U.1    Gertz, K.2    Huang, P.3
  • 48
    • 77049120794 scopus 로고    scopus 로고
    • Long-term stability of recombinant tissue plasminogen activator at-80°C
    • Shaw GJ, Sperling M, Meunier JM. Long-term stability of recombinant tissue plasminogen activator at-80°C. BMC Res Notes 2009; 2:117.
    • (2009) BMC Res Notes , vol.2 , pp. 117
    • Shaw, G.J.1    Sperling, M.2    Meunier, J.M.3
  • 49
    • 0022576043 scopus 로고
    • Analysis of coagulation and fibrinolysis during intravenous infusion of recombinant human tissue-type plasminogen activator in patients with acute myocardial infarction
    • Collen D, Bounameaux H, Cock FD, et al. Analysis of coagulation and fibrinolysis during intravenous infusion of recombinant human tissue-type plasminogen activator in patients with acute myocardial infarction. Circulation 1986; 73(3):511-7. (Pubitemid 16133030)
    • (1986) Circulation , vol.73 , Issue.3 , pp. 511-517
    • Collen, D.1    Bounameaux, H.2    De Cock, F.3
  • 50
    • 0002591417 scopus 로고
    • The absorption, distribution, and excretion of epsilon-aminocaproic acid following oral or intravenous administration to man
    • McNicol G, Fletcher A, Alkjaersig N, Sherry S. The absorption, distribution, and excretion of epsilon-aminocaproic acid following oral or intravenous administration to man. J Lab Clin Med 1962; 59:15-24.
    • (1962) J Lab Clin Med , vol.59 , pp. 15-24
    • McNicol, G.1    Fletcher, A.2    Alkjaersig, N.3    Sherry, S.4
  • 51
    • 33845807903 scopus 로고    scopus 로고
    • Epsilon-Aminocaproic acid inhibition of fibrinolysis in vitro: Should the 'therapeutic' concentration be reconsidered?
    • DOI 10.1097/MBC.0b013e328010a359, PII 0000172120070100000006
    • Nielsen VG, Cankovic L, Steenwyk BL. Epsilon-aminocaproic acid inhibition of fibrinolysis in vitro: should the 'therapeutic' concentration be reconsidered? Blood Coagul Fibrinol 2007; 18:35-9. (Pubitemid 46006271)
    • (2007) Blood Coagulation and Fibrinolysis , vol.18 , Issue.1 , pp. 35-39
    • Nielsen, V.G.1    Cankovic, L.2    Steenwyk, B.L.3
  • 52
    • 0141453790 scopus 로고    scopus 로고
    • Current status of antifibrinolytics in cardiopulmonary bypass and elective deep hypothermic circulatory arrest
    • DOI 10.1016/S0889-8537(03)00042-7
    • Green JA, Spiess BD. Current status of antifibrinolytics in cardiopulmonary bypass and elective deep hypothermic circulatory arrest. Anesth Clin N Am 2003; 21:527-51. (Pubitemid 37169543)
    • (2003) Anesthesiology Clinics of North America , vol.21 , Issue.3 , pp. 527-551
    • Green, J.A.1    Spiess, B.D.2
  • 53
    • 33745319266 scopus 로고    scopus 로고
    • Epsilon aminocaproic acid reduces transfusion requirements in patients with thrombocytopenic hemorrhage
    • DOI 10.1002/cncr.21958
    • Kalmadi S, Tiu R, Lowe C, et al. Epsilon aminocaproic acid reduces transfusion requirements in patients with thrombocytopenic hemorrhage. Cancer 2006; 107(1):136-40. (Pubitemid 43939039)
    • (2006) Cancer , vol.107 , Issue.1 , pp. 136-140
    • Kalmadi, S.1    Tiu, R.2    Lowe, C.3    Jin, T.4    Kalaycio, M.5
  • 54
    • 0028293878 scopus 로고
    • Inhibitory effects of lysine analogues on t-PA induced whole blood clot lysis
    • DOI 10.1016/0049-3848(94)90043-4
    • Krishnamurti C, Vukelja SJ, Alving BM. Inhibitory effects of lysine analogues on t-PA induced whole blood clot lysis. Thromb Res 1994; 73(6):419-30. (Pubitemid 24094574)
    • (1994) Thrombosis Research , vol.73 , Issue.6 , pp. 419-430
    • Krishnamurti, C.1    Vukelja, S.J.2    Alving, B.M.3
  • 55
    • 0023691308 scopus 로고
    • Plasminogen interactions with platelets in plasma
    • Adelman B, Rizk A, Hanners E. Plasminogen interactions with platelets in plasma. Blood 1988; 72(5):1530-5.
    • (1988) Blood , vol.72 , Issue.5 , pp. 1530-1535
    • Adelman, B.1    Rizk, A.2    Hanners, E.3
  • 57
    • 0033646270 scopus 로고    scopus 로고
    • High-resolution MRI characterization of human thrombus using a novel fibrin-targeted paramagnetic nanoparticle contrast agent
    • Yu X, Song SK, Chen J, et al. High-resolution MRI characterization of human thrombus using a novel fibrin-targeted paramagnetic nanoparticle contrast agent. Mag Res Med 2000; 44:867-72.
    • (2000) Mag Res Med , vol.44 , pp. 867-872
    • Yu, X.1    Song, S.K.2    Chen, J.3
  • 58
    • 0022344013 scopus 로고
    • Perforating branches of the middle cerebral artery: Microanatomy and clinical significance of their intracerebral segments
    • Marinkovic SV, Milisavljevic MM, Kovacevic MS, et al. Perforating branches of the middle cerebral artery. Microanatomy and clinical significance of their intracerebral segments. Stroke 1985; 16(6):1022-9. (Pubitemid 16211513)
    • (1985) Stroke , vol.16 , Issue.6 , pp. 1022-1029
    • Marinkovic, S.V.1    Milisavljevic, M.M.2    Kovacevic, M.S.3    Stevic, Z.D.4
  • 59
    • 30944463589 scopus 로고    scopus 로고
    • Microsurgical anatomy of the anterior communicating artery complex in adult Chinese heads
    • DOI 10.1016/j.surneu.2005.05.027, PII S0090301905004064
    • Tao X, Yu XJ, Bhattarai B, et al. Microsurgical anatomy of the anterior communicating artery complex in adult chinese heads. Surg Neurol 2006; 65(2):155-61. (Pubitemid 43112153)
    • (2006) Surgical Neurology , vol.65 , Issue.2 , pp. 155-161
    • Tao, X.1    Yu, X.J.2    Bhattarai, B.3    Li, T.H.4    Jin, H.5    Wei, G.W.6    Ming, J.S.7    Ren, W.8    Jiong, C.9
  • 60
    • 0028932761 scopus 로고
    • Magnetic resonance imaging of deep vein thrombi correlates with response to thrombolytic therapy
    • Francis C, Totterman S. Magnetic resonance imaging of deep vein thrombi correlates with response to thrombolytic therapy. J Thromb Haemost 1995; 73:385-91.
    • (1995) J Thromb Haemost , vol.73 , pp. 385-391
    • Francis, C.1    Totterman, S.2
  • 61
    • 0024448050 scopus 로고
    • Thrombus age and tissue plasminogen activator mediated thrombolysis in rats
    • Loren M, Garcia Frade LJ, Torrado MC, et al. Thrombus age and tissue plasminogen activator mediated thrombolysis in rats. Thromb Res 1989; 56(1):67-75.
    • (1989) Thromb Res , vol.56 , Issue.1 , pp. 67-75
    • Loren, M.1    Garcia Frade, L.J.2    Torrado, M.C.3
  • 62
    • 54049131779 scopus 로고    scopus 로고
    • Tissue plasminogen activator concentration dependence of 120 kHz ultrasoundenhanced thrombolysis
    • Shaw GJ, Meunier JM, Lindsell CJ, et al. Tissue plasminogen activator concentration dependence of 120 kHz ultrasoundenhanced thrombolysis. Ultrasound Med Biol 2008; 34(11):1783-92.
    • (2008) Ultrasound Med Biol , vol.34 , Issue.11 , pp. 1783-1792
    • Shaw, G.J.1    Meunier, J.M.2    Lindsell, C.J.3
  • 63
    • 67649753359 scopus 로고    scopus 로고
    • 120 kHz pulsed ultrasound enhanced thrombolysis with tissue plasminogen activator-loaded echogenic liposomes
    • Meunier JM, Smith DAB, Holland CK, et al. 120 kHz pulsed ultrasound enhanced thrombolysis with tissue plasminogen activator-loaded echogenic liposomes. J Acous Soc Am 2007b; 122:3052.
    • (2007) J Acous Soc Am , vol.122 , pp. 3052
    • Meunier, J.M.1    Smith, D.A.B.2    Holland, C.K.3
  • 64
    • 77957153485 scopus 로고    scopus 로고
    • Making the right choice: Optimizing rt-PA and eptifibatide lysis, an in vitro study
    • Shaw GJ, Meunier JM, Lindsell CJ, et al. Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study. Thromb Res 2010; 126(4):e305-11.
    • (2010) Thromb Res , vol.126 , Issue.4
    • Shaw, G.J.1    Meunier, J.M.2    Lindsell, C.J.3
  • 65
    • 82155185620 scopus 로고    scopus 로고
    • Combination treatment with rt-PA is more effective than rt-PA alone in an in-vitro human clot model
    • Meunier JM, Holland CK, Porter TM, et al. Combination treatment with rt-PA is more effective than rt-PA alone in an in-vitro human clot model. Curr Neurovasc Res 2011; 8(4):305-12.
    • (2011) Curr Neurovasc Res , vol.8 , Issue.4 , pp. 305-312
    • Meunier, J.M.1    Holland, C.K.2    Porter, T.M.3
  • 66
    • 67649753359 scopus 로고    scopus 로고
    • 120 kHz pulsed ultrasound enhanced thrombolysis with tissue plasminogen activator-loaded echogenic liposomes
    • Meunier JM, Smith DAB, Holland CK, et al. 120 kHz pulsed ultrasound enhanced thrombolysis with tissue plasminogen activator-loaded echogenic liposomes. J Acous Soc Am 2007; 122:3052.
    • (2007) J Acous Soc Am , vol.122 , pp. 3052
    • Meunier, J.M.1    Smith, D.A.B.2    Holland, C.K.3
  • 67
    • 57949114499 scopus 로고    scopus 로고
    • Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots
    • Meunier JM, Holland CK, Pancioli AM, et al. Effect of low frequency ultrasound on combined rt-PA and eptifibatide thrombolysis in human clots. Thromb Res 2009; 123(3):528-36.
    • (2009) Thromb Res , vol.123 , Issue.3 , pp. 528-536
    • Meunier, J.M.1    Holland, C.K.2    Pancioli, A.M.3
  • 68
    • 77957153485 scopus 로고    scopus 로고
    • Making the right choice: Optimizing rt-PA and eptifibatide lysis, an in vitro study
    • Shaw GJ, Meunier JM, Lindsell CJ, et al. Making the right choice: optimizing rt-PA and eptifibatide lysis, an in vitro study. Thromb Res 2010; 126(4):305-11.
    • (2010) Thromb Res , vol.126 , Issue.4 , pp. 305-311
    • Shaw, G.J.1    Meunier, J.M.2    Lindsell, C.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.