메뉴 건너뛰기




Volumn 1303, Issue , 2009, Pages 144-150

The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor simvastatin reduces thrombolytic-induced intracerebral hemorrhage in embolized rabbits

Author keywords

Intracerebral hemorrhage; Ischemic stroke; Neuroprotection; Translational science

Indexed keywords

SIMVASTATIN; TISSUE PLASMINOGEN ACTIVATOR;

EID: 72049117774     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.09.064     Document Type: Article
Times cited : (17)

References (49)
  • 2
    • 33645853175 scopus 로고    scopus 로고
    • Statin safety: an overview and assessment of the data-2005
    • Bays H. Statin safety: an overview and assessment of the data-2005. Am. J. Cardiol. 97 (2006) 6C-26C
    • (2006) Am. J. Cardiol. , vol.97
    • Bays, H.1
  • 3
    • 0036368013 scopus 로고    scopus 로고
    • Benefits and menaces related to the use of statins in patients after renal transplantation
    • Chmielewski M., Zdrojewski Z., and Rutkowski B. Benefits and menaces related to the use of statins in patients after renal transplantation. Ann. Transplant. 7 (2002) 6-10
    • (2002) Ann. Transplant. , vol.7 , pp. 6-10
    • Chmielewski, M.1    Zdrojewski, Z.2    Rutkowski, B.3
  • 4
    • 26444561886 scopus 로고    scopus 로고
    • Neuroprotective effect of simvastatin in stroke: a comparison between adult and neonatal rat models of cerebral ischemia
    • Cimino M., Balduini W., Carloni S., Gelosa P., Guerrini U., Tremoli E., and Sironi L. Neuroprotective effect of simvastatin in stroke: a comparison between adult and neonatal rat models of cerebral ischemia. Neurotoxicology 26 (2005) 929-933
    • (2005) Neurotoxicology , vol.26 , pp. 929-933
    • Cimino, M.1    Balduini, W.2    Carloni, S.3    Gelosa, P.4    Guerrini, U.5    Tremoli, E.6    Sironi, L.7
  • 6
    • 0030663693 scopus 로고    scopus 로고
    • Vascular effects of statins in stroke
    • Delanty N., and Vaughan C.J. Vascular effects of statins in stroke. Stroke 28 (1997) 2315-2320
    • (1997) Stroke , vol.28 , pp. 2315-2320
    • Delanty, N.1    Vaughan, C.J.2
  • 10
    • 2642559507 scopus 로고    scopus 로고
    • Beyond the laboratory: clinical implications for statin pleiotropy
    • Halcox J.P., and Deanfield J.E. Beyond the laboratory: clinical implications for statin pleiotropy. Circulation 109 (2004) II42-II48
    • (2004) Circulation , vol.109
    • Halcox, J.P.1    Deanfield, J.E.2
  • 11
    • 0030802435 scopus 로고    scopus 로고
    • Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials
    • Hebert P.R., Gaziano J.M., Chan K.S., and Hennekens C.H. Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials. Jama 278 (1997) 313-321
    • (1997) Jama , vol.278 , pp. 313-321
    • Hebert, P.R.1    Gaziano, J.M.2    Chan, K.S.3    Hennekens, C.H.4
  • 12
    • 0034701033 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors (statins): a promising approach to stroke prevention
    • Hess D.C., Demchuk A.M., Brass L.M., and Yatsu F.M. HMG-CoA reductase inhibitors (statins): a promising approach to stroke prevention. Neurology 54 (2000) 790-796
    • (2000) Neurology , vol.54 , pp. 790-796
    • Hess, D.C.1    Demchuk, A.M.2    Brass, L.M.3    Yatsu, F.M.4
  • 13
    • 4544368193 scopus 로고    scopus 로고
    • Stroke-incidence, mortality, morbidity and risk
    • Ingall T. Stroke-incidence, mortality, morbidity and risk. J. Insur. Med. 36 (2004) 143-152
    • (2004) J. Insur. Med. , vol.36 , pp. 143-152
    • Ingall, T.1
  • 14
    • 3042688440 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor, atorvastatin, promotes sensorimotor recovery, suppressing acute inflammatory reaction after experimental intracerebral hemorrhage
    • Jung K.H., Chu K., Jeong S.W., Han S.Y., Lee S.T., Kim J.Y., Kim M., and Roh J.K. HMG-CoA reductase inhibitor, atorvastatin, promotes sensorimotor recovery, suppressing acute inflammatory reaction after experimental intracerebral hemorrhage. Stroke 35 (2004) 1744-1749
    • (2004) Stroke , vol.35 , pp. 1744-1749
    • Jung, K.H.1    Chu, K.2    Jeong, S.W.3    Han, S.Y.4    Lee, S.T.5    Kim, J.Y.6    Kim, M.7    Roh, J.K.8
  • 15
    • 70349663983 scopus 로고    scopus 로고
    • Simvastatin and atorvastatin improve neurological outcome after experimental intracerebral hemorrhage
    • Karki K., Knight R.A., Han Y., Yang D., Zhang J., Ledbetter K.A., Chopp M., and Seyfried D.M. Simvastatin and atorvastatin improve neurological outcome after experimental intracerebral hemorrhage. Stroke 40 10 (2009) 3384-3389
    • (2009) Stroke , vol.40 , Issue.10 , pp. 3384-3389
    • Karki, K.1    Knight, R.A.2    Han, Y.3    Yang, D.4    Zhang, J.5    Ledbetter, K.A.6    Chopp, M.7    Seyfried, D.M.8
  • 16
    • 0031174941 scopus 로고    scopus 로고
    • Cholesterol and atherosclerosis: a contemporary perspective
    • Kashyap M.L. Cholesterol and atherosclerosis: a contemporary perspective. Ann. Acad. Med. Singap. 26 (1997) 517-523
    • (1997) Ann. Acad. Med. Singap. , vol.26 , pp. 517-523
    • Kashyap, M.L.1
  • 17
    • 57349138312 scopus 로고    scopus 로고
    • A case control study of statin and magnesium administration in patients after aneurysmal subarachnoid hemorrhage: incidence of delayed cerebral ischemia and mortality
    • Kerz T., Victor A., Beyer C., Trapp I., Heid F., and Reisch R. A case control study of statin and magnesium administration in patients after aneurysmal subarachnoid hemorrhage: incidence of delayed cerebral ischemia and mortality. Neurol. Res. 30 (2008) 893-897
    • (2008) Neurol. Res. , vol.30 , pp. 893-897
    • Kerz, T.1    Victor, A.2    Beyer, C.3    Trapp, I.4    Heid, F.5    Reisch, R.6
  • 19
    • 41749089775 scopus 로고    scopus 로고
    • Statin use was not associated with less vasospasm or improved outcome after subarachnoid hemorrhage
    • discussion 427-30
    • Kramer A.H., Gurka M.J., Nathan B., Dumont A.S., Kassell N.F., and Bleck T.P. Statin use was not associated with less vasospasm or improved outcome after subarachnoid hemorrhage. Neurosurgery 62 (2008) 422-427 discussion 427-30
    • (2008) Neurosurgery , vol.62 , pp. 422-427
    • Kramer, A.H.1    Gurka, M.J.2    Nathan, B.3    Dumont, A.S.4    Kassell, N.F.5    Bleck, T.P.6
  • 20
    • 34548120889 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha is involved in thrombolytic-induced hemorrhage following embolic strokes in rabbits
    • Lapchak P.A. Tumor necrosis factor-alpha is involved in thrombolytic-induced hemorrhage following embolic strokes in rabbits. Brain Res. 1167 (2007) 123-128
    • (2007) Brain Res. , vol.1167 , pp. 123-128
    • Lapchak, P.A.1
  • 21
    • 0033666754 scopus 로고    scopus 로고
    • Metalloproteinase inhibition reduces thrombolytic (tissue plasminogen activator)-induced hemorrhage after thromboembolic stroke
    • Lapchak P.A., Chapman D.F., and Zivin J.A. Metalloproteinase inhibition reduces thrombolytic (tissue plasminogen activator)-induced hemorrhage after thromboembolic stroke. Stroke 31 (2000) 3034-3040
    • (2000) Stroke , vol.31 , pp. 3034-3040
    • Lapchak, P.A.1    Chapman, D.F.2    Zivin, J.A.3
  • 22
    • 0036281174 scopus 로고    scopus 로고
    • Effects of the spin trap agent disodium-[tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) on intracerebral hemorrhage in a rabbit large clot embolic stroke model: combination studies with tissue plasminogen activator
    • Lapchak P.A., Araujo D.M., Song D., Wei J., Purdy R., and Zivin J.A. Effects of the spin trap agent disodium-[tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) on intracerebral hemorrhage in a rabbit large clot embolic stroke model: combination studies with tissue plasminogen activator. Stroke 33 (2002) 1665-1670
    • (2002) Stroke , vol.33 , pp. 1665-1670
    • Lapchak, P.A.1    Araujo, D.M.2    Song, D.3    Wei, J.4    Purdy, R.5    Zivin, J.A.6
  • 23
    • 55749094157 scopus 로고    scopus 로고
    • Safety profile of transcranial near-infrared laser therapy administered in combination with thrombolytic therapy to embolized rabbits
    • Lapchak P.A., Han M.K., Salgado K.F., Streeter J., and Zivin J.A. Safety profile of transcranial near-infrared laser therapy administered in combination with thrombolytic therapy to embolized rabbits. Stroke 39 (2008) 3073-3078
    • (2008) Stroke , vol.39 , pp. 3073-3078
    • Lapchak, P.A.1    Han, M.K.2    Salgado, K.F.3    Streeter, J.4    Zivin, J.A.5
  • 24
    • 0036583443 scopus 로고    scopus 로고
    • Statins and ischemic stroke
    • Liao J.K. Statins and ischemic stroke. Atheroscler. Suppl. 3 (2002) 21-25
    • (2002) Atheroscler. Suppl. , vol.3 , pp. 21-25
    • Liao, J.K.1
  • 25
    • 33745726883 scopus 로고    scopus 로고
    • Atorvastatin downregulates tissue plasminogen activator-aggravated genes mediating coagulation and vascular permeability in single cerebral endothelial cells captured by laser microdissection
    • Liu X.S., Zhang Z.G., Zhang L., Morris D.C., Kapke A., Lu M., and Chopp M. Atorvastatin downregulates tissue plasminogen activator-aggravated genes mediating coagulation and vascular permeability in single cerebral endothelial cells captured by laser microdissection. J. Cereb. Blood Flow Metab. 26 (2006) 787-796
    • (2006) J. Cereb. Blood Flow Metab. , vol.26 , pp. 787-796
    • Liu, X.S.1    Zhang, Z.G.2    Zhang, L.3    Morris, D.C.4    Kapke, A.5    Lu, M.6    Chopp, M.7
  • 27
    • 0036644958 scopus 로고    scopus 로고
    • Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinases
    • Lo E.H., Wang X., and Cuzner M.L. Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinases. J. Neurosci. Res. 69 (2002) 1-9
    • (2002) J. Neurosci. Res. , vol.69 , pp. 1-9
    • Lo, E.H.1    Wang, X.2    Cuzner, M.L.3
  • 28
    • 0024564242 scopus 로고
    • Tissue plasminogen activator-mediated thrombolysis of cerebral emboli and its effect on hemorrhagic infarction in rabbits
    • Lyden P.D., Zivin J.A., Clark W.A., Madden K., Sasse K.C., Mazzarella V.A., Terry R.D., and Press G.A. Tissue plasminogen activator-mediated thrombolysis of cerebral emboli and its effect on hemorrhagic infarction in rabbits. Neurology 39 (1989) 703
    • (1989) Neurology , vol.39 , pp. 703
    • Lyden, P.D.1    Zivin, J.A.2    Clark, W.A.3    Madden, K.4    Sasse, K.C.5    Mazzarella, V.A.6    Terry, R.D.7    Press, G.A.8
  • 30
    • 15944377914 scopus 로고    scopus 로고
    • Treatment with statins in the acute phase of ischemic stroke
    • Montaner J. Treatment with statins in the acute phase of ischemic stroke. Expert Rev. Neurother. 5 (2005) 211-221
    • (2005) Expert Rev. Neurother. , vol.5 , pp. 211-221
    • Montaner, J.1
  • 31
    • 1542284148 scopus 로고    scopus 로고
    • HMG CoA reductase inhibitors (statins): use in stroke prevention and outcome after stroke
    • Moonis M., and Fisher M. HMG CoA reductase inhibitors (statins): use in stroke prevention and outcome after stroke. Expert Rev. Neurother. 4 (2004) 241-247
    • (2004) Expert Rev. Neurother. , vol.4 , pp. 241-247
    • Moonis, M.1    Fisher, M.2
  • 33
    • 0042623437 scopus 로고    scopus 로고
    • Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion
    • Pfefferkorn T., and Rosenberg G.A. Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion. Stroke 34 (2003) 2025-2030
    • (2003) Stroke , vol.34 , pp. 2025-2030
    • Pfefferkorn, T.1    Rosenberg, G.A.2
  • 34
    • 0035793934 scopus 로고    scopus 로고
    • Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures
    • Rosenberg G.A., Cunningham L.A., Wallace J., Alexander S., Estrada E.Y., Grossetete M., Razhagi A., Miller K., and Gearing A. Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures. Brain Res. 893 (2001) 104-112
    • (2001) Brain Res. , vol.893 , pp. 104-112
    • Rosenberg, G.A.1    Cunningham, L.A.2    Wallace, J.3    Alexander, S.4    Estrada, E.Y.5    Grossetete, M.6    Razhagi, A.7    Miller, K.8    Gearing, A.9
  • 35
    • 33144483670 scopus 로고    scopus 로고
    • The role of statins in clinical medicine-LDL-cholesterol lowering and beyond
    • Rutishauser J. The role of statins in clinical medicine-LDL-cholesterol lowering and beyond. Swiss Med. Wkly. 136 (2006) 41-49
    • (2006) Swiss Med. Wkly. , vol.136 , pp. 41-49
    • Rutishauser, J.1
  • 36
    • 33646689805 scopus 로고    scopus 로고
    • Statin-mediated protective effects in the central nervous system: general mechanisms and putative role of stress proteins
    • Schmeer C., Kretz A., and Isenmann S. Statin-mediated protective effects in the central nervous system: general mechanisms and putative role of stress proteins. Restor. Neurol. Neurosci. 24 (2006) 79-95
    • (2006) Restor. Neurol. Neurosci. , vol.24 , pp. 79-95
    • Schmeer, C.1    Kretz, A.2    Isenmann, S.3
  • 37
    • 3042656548 scopus 로고    scopus 로고
    • Improvement in neurological outcome after administration of atorvastatin following experimental intracerebral hemorrhage in rats
    • Seyfried D., Han Y., Lu D., Chen J., Bydon A., and Chopp M. Improvement in neurological outcome after administration of atorvastatin following experimental intracerebral hemorrhage in rats. J. Neurosurg. 101 (2004) 104-107
    • (2004) J. Neurosurg. , vol.101 , pp. 104-107
    • Seyfried, D.1    Han, Y.2    Lu, D.3    Chen, J.4    Bydon, A.5    Chopp, M.6
  • 38
    • 67049119523 scopus 로고    scopus 로고
    • From here to JUPITER: identifying new patients for statin therapy using data from the 1999-2004 National Health and Nutrition Examination Survey
    • Spatz E.S., Canavan M.E., and Desai M.M. From here to JUPITER: identifying new patients for statin therapy using data from the 1999-2004 National Health and Nutrition Examination Survey. Circ. Cardiovasc. Qual. Outcomes 2 (2009) 41-48
    • (2009) Circ. Cardiovasc. Qual. Outcomes , vol.2 , pp. 41-48
    • Spatz, E.S.1    Canavan, M.E.2    Desai, M.M.3
  • 39
    • 59349103744 scopus 로고    scopus 로고
    • Simvastatin attenuation of cerebral vasospasm after subarachnoid hemorrhage in rats via increased phosphorylation of Akt and endothelial nitric oxide synthase
    • Sugawara T., Ayer R., Jadhav V., Chen W., Tsubokawa T., and Zhang J.H. Simvastatin attenuation of cerebral vasospasm after subarachnoid hemorrhage in rats via increased phosphorylation of Akt and endothelial nitric oxide synthase. J. Neurosci. Res. 86 (2008) 3635-3643
    • (2008) J. Neurosci. Res. , vol.86 , pp. 3635-3643
    • Sugawara, T.1    Ayer, R.2    Jadhav, V.3    Chen, W.4    Tsubokawa, T.5    Zhang, J.H.6
  • 40
    • 66649122397 scopus 로고    scopus 로고
    • Simvastatin attenuates cerebral vasospasm and improves outcomes by upregulation of PI3K/Akt pathway in a rat model of subarachnoid hemorrhage
    • Sugawara T., Jadhav V., Ayer R., and Zhang J. Simvastatin attenuates cerebral vasospasm and improves outcomes by upregulation of PI3K/Akt pathway in a rat model of subarachnoid hemorrhage. Acta Neurochir. Suppl. 102 (2008) 391-394
    • (2008) Acta Neurochir. Suppl. , vol.102 , pp. 391-394
    • Sugawara, T.1    Jadhav, V.2    Ayer, R.3    Zhang, J.4
  • 41
    • 33746191327 scopus 로고    scopus 로고
    • Pravastatin reduces microvascular basal lamina damage following focal cerebral ischemia and reperfusion
    • Trinkl A., Vosko M.R., Wunderlich N., Dichgans M., and Hamann G.F. Pravastatin reduces microvascular basal lamina damage following focal cerebral ischemia and reperfusion. Eur. J. Neurosci. 24 (2006) 520-526
    • (2006) Eur. J. Neurosci. , vol.24 , pp. 520-526
    • Trinkl, A.1    Vosko, M.R.2    Wunderlich, N.3    Dichgans, M.4    Hamann, G.F.5
  • 42
    • 50049112333 scopus 로고    scopus 로고
    • Lipid profile, statin use, and outcome after intravenous thrombolysis for acute ischaemic stroke
    • Uyttenboogaart M., Koch M.W., Koopman K., Vroomen P.C., Luijckx G.J., and De Keyser J. Lipid profile, statin use, and outcome after intravenous thrombolysis for acute ischaemic stroke. J. Neurol. 255 (2008) 875-880
    • (2008) J. Neurol. , vol.255 , pp. 875-880
    • Uyttenboogaart, M.1    Koch, M.W.2    Koopman, K.3    Vroomen, P.C.4    Luijckx, G.J.5    De Keyser, J.6
  • 44
    • 33644814044 scopus 로고    scopus 로고
    • Lipids and stroke: the opportunity of lipid-lowering treatment
    • Vivancos-Mora J., and Gil-Nunez A.C. Lipids and stroke: the opportunity of lipid-lowering treatment. Cerebrovasc. Dis. 20 Suppl. 2 (2005) 53-67
    • (2005) Cerebrovasc. Dis. , vol.20 , Issue.SUPPL. 2 , pp. 53-67
    • Vivancos-Mora, J.1    Gil-Nunez, A.C.2
  • 45
    • 0346690415 scopus 로고    scopus 로고
    • The pleiotropic effects of HMG-CoA reductase inhibitors: their role in osteoporosis and dementia
    • Waldman A., and Kritharides L. The pleiotropic effects of HMG-CoA reductase inhibitors: their role in osteoporosis and dementia. Drugs 63 (2003) 139-152
    • (2003) Drugs , vol.63 , pp. 139-152
    • Waldman, A.1    Kritharides, L.2
  • 46
    • 33745950917 scopus 로고    scopus 로고
    • Reduction of tissue plasminogen activator-induced matrix metalloproteinase-9 by simvastatin in astrocytes
    • Wang S., Lee S.R., Guo S.Z., Kim W.J., Montaner J., Wang X., and Lo E.H. Reduction of tissue plasminogen activator-induced matrix metalloproteinase-9 by simvastatin in astrocytes. Stroke 37 (2006) 1910-1912
    • (2006) Stroke , vol.37 , pp. 1910-1912
    • Wang, S.1    Lee, S.R.2    Guo, S.Z.3    Kim, W.J.4    Montaner, J.5    Wang, X.6    Lo, E.H.7
  • 47
    • 0036118915 scopus 로고    scopus 로고
    • Pleiotropic effects of HMG-CoA reductase inhibitors
    • Werner N., Nickenig G., and Laufs U. Pleiotropic effects of HMG-CoA reductase inhibitors. Basic Res. Cardiol. 97 (2002) 105-116
    • (2002) Basic Res. Cardiol. , vol.97 , pp. 105-116
    • Werner, N.1    Nickenig, G.2    Laufs, U.3
  • 48
    • 33745894649 scopus 로고    scopus 로고
    • Simvastatin attenuates hypertrophic responses induced by cardiotrophin-1 via JAK-STAT pathway in cultured cardiomyocytes
    • Wu L., Zhao L., Zheng Q., Shang F., Wang X., Wang L., and Lang B. Simvastatin attenuates hypertrophic responses induced by cardiotrophin-1 via JAK-STAT pathway in cultured cardiomyocytes. Mol. Cell Biochem. 284 (2006) 65-71
    • (2006) Mol. Cell Biochem. , vol.284 , pp. 65-71
    • Wu, L.1    Zhao, L.2    Zheng, Q.3    Shang, F.4    Wang, X.5    Wang, L.6    Lang, B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.