Myocardial redox state predicts in-hospital clinical outcome after cardiac surgery: Effects of short-term pre-operative statin treatment

Journal of the American College of Cardiology

Volumn 59, Issue 1, 2012, Pages 60-70

  Antoniades, Charalambos ^a,b   Demosthenous, Michael ^b   Reilly, Svetlana ^a   Margaritis, Marios ^a   Zhang, Mei Hua ^a   Antonopoulos, Alexios ^b   Marinou, Kyriakoula ^b   Nahar, Keshav ^a   Jayaram, Raja ^a   Tousoulis, Dimitris ^b   Bakogiannis, Constantinos ^b   Sayeed, Rana ^c   Triantafyllou, Costas ^d   Koumallos, Nikolaos ^d   Psarros, Costas ^b   Miliou, Antigoni ^b   Stefanadis, Christodoulos ^b   Channon, Keith M ^a   Casadei, Barbara ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^d HIPPOKRATION HOSPITAL   (Greece)

Author keywords

atrial fibrillation; cardiac surgery; myocardium; NADPH oxidase; statins

Indexed keywords

ATORVASTATIN; INOTROPIC AGENT; MEVALONIC ACID; PEROXYNITRITE; PLACEBO; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

AGED; ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; FOLLOW UP; HEART ATRIUM APPENDAGE; HEART ATRIUM FIBRILLATION; HEART MUSCLE; HEART MUSCLE OXYGEN CONSUMPTION; HEART SURGERY; HUMAN; HUMAN TISSUE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; OXIDATION REDUCTION STATE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROGNOSIS;

AGED; CARDIAC SURGICAL PROCEDURES; CONFIDENCE INTERVALS; CORONARY ARTERY BYPASS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HEPTANOIC ACIDS; HOSPITAL MORTALITY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KAPLAN-MEIER ESTIMATE; LIPID PEROXIDATION; MALE; MIDDLE AGED; MYOCARDIUM; OXIDATION-REDUCTION; POSTOPERATIVE COMPLICATIONS; PREDICTIVE VALUE OF TESTS; PREOPERATIVE CARE; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; PYRROLES; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84055182538     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2011.08.062     Document Type: Article

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