Cholinergic depletion in nucleus accumbens impairs mesocortical dopamine activation and cognitive function in rats

Neuropharmacology

Volumn 63, Issue 6, 2012, Pages 1075-1084

  Laplante, Franois ^a   Zhang, Zi Wei ^b   Huppé Gourgues, Frédéric ^b   Dufresne, Marc M ^c   Vaucher, Elvire ^b   Sullivan, Ron M ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c Food and Water Watch Council of Canadians   (Canada)

Author keywords

Animal model; Immunohistochemistry; In vivo voltammetry; Saporin; Schizophrenia; Ventral striatum

Indexed keywords

ACETYLCHOLINE; CHOLINE ACETYLTRANSFERASE; DOPAMINE; IMMUNOTOXIN; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BRAIN DAMAGE; CELL LOSS; CHOLINERGIC NERVE CELL; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DOPAMINE RELEASE; IN VIVO STUDY; LIMBIC CORTEX; MALE; MENTAL PERFORMANCE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; VARICOSIS; VENTROMEDIAL PREFRONTAL CORTEX;

ACETYLCHOLINE; ANIMALS; COGNITION; DOPAMINE; ELECTROCHEMISTRY; ELECTRODES, IMPLANTED; IMMUNOHISTOCHEMISTRY; MALE; MEMORY, SHORT-TERM; NERVE FIBERS; NEURONS; NEUROTRANSMITTER AGENTS; NUCLEUS ACCUMBENS; PARASYMPATHETIC NERVOUS SYSTEM; PREFRONTAL CORTEX; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; STEREOTAXIC TECHNIQUES; TYROSINE 3-MONOOXYGENASE;

EID: 84865201160     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.07.033     Document Type: Article

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