메뉴 건너뛰기




Volumn 30, Issue 3, 2012, Pages 708-712

The bone anabolic carotenoid p-hydroxycinnamic acid promotes osteoblast mineralization and suppresses osteoclast differentiation by antagonizing NF-κB activation

Author keywords

Nuclear factor B; Osteoblast; Osteoclast; Osteoporosis; p hydroxycinnamic acid

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; PARA COUMARIC ACID; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84865195506     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.1043     Document Type: Article
Times cited : (29)

References (31)
  • 1
    • 52649099382 scopus 로고    scopus 로고
    • Update on the role of vitamin K in skeletal health
    • Shea MK and Booth SL: Update on the role of vitamin K in skeletal health. Nutr Rev 66: 549-557, 2008.
    • (2008) Nutr Rev , vol.66 , pp. 549-557
    • Shea, M.K.1    Booth, S.L.2
  • 2
    • 79960751192 scopus 로고    scopus 로고
    • Quercetin, a potent suppressor of NF-κB and Smad activation in osteoblasts
    • Yamaguchi M and Weitzmann MN: Quercetin, a potent suppressor of NF-κB and Smad activation in osteoblasts. Int J Mol Med 28: 521-525, 2011.
    • (2011) Int J Mol Med , vol.28 , pp. 521-525
    • Yamaguchi, M.1    Weitzmann, M.N.2
  • 3
    • 80051552844 scopus 로고    scopus 로고
    • Zinc stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-kappaB activation
    • Yamaguchi M and Weitzmann MN: Zinc stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-kappaB activation. Mol Cell Biochem 355: 179-186, 2011.
    • (2011) Mol Cell Biochem , vol.355 , pp. 179-186
    • Yamaguchi, M.1    Weitzmann, M.N.2
  • 4
    • 78651069683 scopus 로고    scopus 로고
    • 2 stimulates osteoblastogenesis and suppresses osteoclastogenesis by suppressing NF-κB activation
    • 2 stimulates osteoblastogenesis and suppresses osteoclastogenesis by suppressing NF-κB activation. Int J Mol Med 27: 3-14, 2011.
    • (2011) Int J Mol Med , vol.27 , pp. 3-14
    • Yamaguchi, M.1    Weitzmann, M.N.2
  • 5
    • 80053468944 scopus 로고    scopus 로고
    • Honokiol stimulates osteoblastogenesis by suppressing NF-κB activation
    • Yamaguchi M, Arbiser JL and Weitzmann MN: Honokiol stimulates osteoblastogenesis by suppressing NF-κB activation. Int J Mol Med 28: 1049-1053, 2011.
    • (2011) Int J Mol Med , vol.28 , pp. 1049-1053
    • Yamaguchi, M.1    Arbiser, J.L.2    Weitzmann, M.N.3
  • 6
    • 69549122467 scopus 로고    scopus 로고
    • The bone anabolic carotenoids p-hydroxycinnamic acid and β-cryptoxanthin antagonize NF-κB activation in MC3T3 preosteoblasts
    • Yamaguchi M and Weitzmann MN: The bone anabolic carotenoids p-hydroxycinnamic acid and β-cryptoxanthin antagonize NF-κB activation in MC3T3 preosteoblasts. Mol Med Rep 2: 641-644, 2009.
    • (2009) Mol Med Rep , vol.2 , pp. 641-644
    • Yamaguchi, M.1    Weitzmann, M.N.2
  • 7
    • 70350761408 scopus 로고    scopus 로고
    • The bone anabolic carotenoid β-cryptoxanthin enhances transforming growth factor-β1-induced Smad activation in MC3T3 preosteoblasts
    • Yamaguchi M and Weitzmann MN: The bone anabolic carotenoid β-cryptoxanthin enhances transforming growth factor-β1-induced Smad activation in MC3T3 preosteoblasts. Int J Mol Med 24: 671-675, 2009.
    • (2009) Int J Mol Med , vol.24 , pp. 671-675
    • Yamaguchi, M.1    Weitzmann, M.N.2
  • 8
    • 45749124735 scopus 로고    scopus 로고
    • RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice
    • DOI 10.1172/JCI33392
    • Vaira S, Alhawagri M, Anwisye I, Kitaura H, Faccio R and Novack DV: RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice. J Clin Invest 118: 2088-2097, 2008. (Pubitemid 351872328)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.6 , pp. 2088-2097
    • Vaira, S.1    Alhawagri, M.2    Anwisye, I.3    Kitaura, H.4    Faccio, R.5    Novack, D.V.6
  • 9
    • 0032991354 scopus 로고    scopus 로고
    • Required and nonessential functions of nuclear factor-kappa B in bone cells
    • DOI 10.1016/S8756-3282(99)00105-2, PII S8756328299001052
    • Boyce BF, Xing L, Franzoso G and Siebenlist U: Required and nonessential functions of nuclear factor-kappaB in bone cells. Bone 25: 137-139, 1999. (Pubitemid 29322078)
    • (1999) Bone , vol.25 , Issue.1 , pp. 137-139
    • Boyce, B.F.1    Xing, L.2    Franzoso, G.3    Siebenlist, U.4
  • 11
    • 4444306858 scopus 로고    scopus 로고
    • The IκB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis
    • DOI 10.1074/jbc.C400258200
    • Dai S, Hirayama T, Abbas S and Abu-Amer Y: The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis. J Biol Chem 279: 37219-37222, 2004. (Pubitemid 39195425)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.36 , pp. 37219-37222
    • Dai, S.1    Hirayama, T.2    Abbas, S.3    Abu-Amer, Y.4
  • 12
    • 33847364101 scopus 로고    scopus 로고
    • SDX-308, a nonsteroidal anti-inflammatory agent, inhibits NF-κB activity, resulting in strong inhibition of osteoclast formation/activity and multiple myeloma cell growth
    • DOI 10.1182/blood-2006-07-027458
    • Feng R, Anderson G, Xiao G, et al: SDX-308, a nonsteroidal anti-inflammatory agent, inhibits NF-kappaB activity, resulting in strong inhibition of osteoclast formation/activity and multiple myeloma cell growth. Blood 109: 2130-2138, 2007. (Pubitemid 46348215)
    • (2007) Blood , vol.109 , Issue.5 , pp. 2130-2138
    • Feng, R.1    Anderson, G.2    Xiao, G.3    Elliott, G.4    Leoni, L.5    Mapara, M.Y.6    Roodman, G.D.7    Lentzsch, S.8
  • 13
    • 0242409906 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha: Molecular and cellular mechanisms in skeletal pathology
    • Nanes MS: Tumor necrosis factor-alpha: molecular and cellular mechanisms in skeletal pathology. Gene 321: 1-15, 2003.
    • (2003) Gene , vol.321 , pp. 1-15
    • Nanes, M.S.1
  • 14
    • 34447509873 scopus 로고    scopus 로고
    • Endogenous TNFα lowers maximum peak bone mass and inhibits osteoblastic smad activation through NF-κB
    • DOI 10.1359/jbmr.070121
    • Li Y, Li A, Strait K, Zhang H, Nanes MS and Weitzmann MN: Endogenous TNFalpha lowers maximum peak bone mass and inhibits osteoblastic Smad activation, through NF-kappaB. J Bone Miner Res 22: 646-655, 2007. (Pubitemid 351339092)
    • (2007) Journal of Bone and Mineral Research , vol.22 , Issue.5 , pp. 646-655
    • Li, Y.1    Li, A.2    Strait, K.3    Zhang, H.4    Nanes, M.S.5    Weitzmann, M.N.6
  • 15
    • 77953402288 scopus 로고    scopus 로고
    • Restoration of regenerative osteoblastogenesis in aged mice: Modulation of TNF
    • Wahl EC, Aronson J, Liu L, et al: Restoration of regenerative osteoblastogenesis in aged mice: modulation of TNF. J Bone Miner Res 25: 114-123, 2010.
    • (2010) J Bone Miner Res , vol.25 , pp. 114-123
    • Wahl, E.C.1    Aronson, J.2    Liu, L.3
  • 16
    • 74249103244 scopus 로고    scopus 로고
    • Direct bone formation during distraction osteogenesis does not require TNFalpha receptors and elevated serum TNFalpha fails to inhibit bone formation in TNFR1 deficient mice
    • Wahl EC, Aronson J, Liu L, et al: Direct bone formation during distraction osteogenesis does not require TNFalpha receptors and elevated serum TNFalpha fails to inhibit bone formation in TNFR1 deficient mice. Bone 46: 410-417, 2010.
    • (2010) Bone , vol.46 , pp. 410-417
    • Wahl, E.C.1    Aronson, J.2    Liu, L.3
  • 17
    • 67349238305 scopus 로고    scopus 로고
    • Inhibition of osteoblastic bone formation by nuclear factor-kappaB
    • Chang J, Wang Z, Tang E, et al: Inhibition of osteoblastic bone formation by nuclear factor-kappaB. Nat Med 15: 682-689, 2009.
    • (2009) Nat Med , vol.15 , pp. 682-689
    • Chang, J.1    Wang, Z.2    Tang, E.3
  • 18
    • 72149132820 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha represses bone morphogenetic protein (BMP) signaling by interfering with the DNA binding of Smads through the activation of NF-kappaB
    • Yamazaki M, Fukushima H, Shin M, et al: Tumor necrosis factor alpha represses bone morphogenetic protein (BMP) signaling by interfering with the DNA binding of Smads through the activation of NF-kappaB. J Biol Chem 284: 35987-35995, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 35987-35995
    • Yamazaki, M.1    Fukushima, H.2    Shin, M.3
  • 19
    • 53149122891 scopus 로고    scopus 로고
    • Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins
    • Guo R, Yamashita M, Zhang Q, et al: Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins. J Biol Chem 283: 23084-23092, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 23084-23092
    • Guo, R.1    Yamashita, M.2    Zhang, Q.3
  • 20
  • 21
    • 33744769395 scopus 로고    scopus 로고
    • Phytocomponent p-hydroxycinnamic acid stimulates bone formation and inhibits bone resorption in rat femoral tissues in vitro
    • DOI 10.1007/s11010-006-9175-x
    • Lai YL and Yamaguchi M: Phytocomponent p-hydroxycinnamic acid stimulates bone formation and inhibits bone resorption in rat femoral tissues in vitro. Mol Cell Biochem 292: 45-52, 2006. (Pubitemid 44697398)
    • (2006) Molecular and Cellular Biochemistry , vol.292 , Issue.1-2 , pp. 45-52
    • Lai, Y.L.1    Yamaguchi, M.2
  • 22
    • 35148877647 scopus 로고    scopus 로고
    • Phytocomponent p-hydroxycinnamic acid inhibits osteoclast-like cell formation in mouse bone marrow cultures
    • Lai YL and Yamaguchi M: Phytocomponent p-hydroxycinnamic acid inhibits osteoclast-like cell formation in mouse bone marrow cultures. Int J Mol Med 19: 123-128, 2007.
    • (2007) Int J Mol Med , vol.19 , pp. 123-128
    • Lai, Y.L.1    Yamaguchi, M.2
  • 23
    • 41349090133 scopus 로고    scopus 로고
    • Oral administration of phytocomponent p-hydroxycinnamic acid prevents bone loss in ovariectomized rats
    • Yamaguchi M, Lai YL, Uchiyama S and Nakagawa T: Oral administration of phytocomponent p-hydroxycinnamic acid prevents bone loss in ovariectomized rats. Mol Cell Biochem 311: 31-36, 2008.
    • (2008) Mol Cell Biochem , vol.311 , pp. 31-36
    • Yamaguchi, M.1    Lai, Y.L.2    Uchiyama, S.3    Nakagawa, T.4
  • 24
    • 34248550073 scopus 로고    scopus 로고
    • Oral administration of phytocomponent p-hydroxycinnamic acid has a preventive effect on bone loss in streptozotocin-induced diabetic rats
    • Yamaguchi M, Uchiyama S and Lai YL: Oral administration of phytocomponent p-hydroxycinnamic acid has a preventive effect on bone loss in streptozotocin-induced diabetic rats. Int J Mol Med 19: 803-807, 2007.
    • (2007) Int J Mol Med , vol.19 , pp. 803-807
    • Yamaguchi, M.1    Uchiyama, S.2    Lai, Y.L.3
  • 25
    • 0034183307 scopus 로고    scopus 로고
    • Anabolic effect of genistein in osteoblastic MC3T3-E1 cells
    • Sugimoto E and Yamaguchi M: Anabolic effect of genistein in osteoblastic MC3T3-E1 cells. Int J Mol Med 5: 515-520, 2000.
    • (2000) Int J Mol Med , vol.5 , pp. 515-520
    • Sugimoto, E.1    Yamaguchi, M.2
  • 27
    • 33646396235 scopus 로고    scopus 로고
    • Estrogen deficiency and bone loss: An inflammatory tale
    • Weitzmann MN and Pacifici R: Estrogen deficiency and bone loss: an inflammatory tale. J Clin Invest 116: 1186-1194, 2006.
    • (2006) J Clin Invest , vol.116 , pp. 1186-1194
    • Weitzmann, M.N.1    Pacifici, R.2
  • 28
    • 0033708837 scopus 로고    scopus 로고
    • Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha
    • Cenci S, Weitzmann MN, Roggia C, et al: Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alpha. J Clin Invest 106: 1229-1237, 2000.
    • (2000) J Clin Invest , vol.106 , pp. 1229-1237
    • Cenci, S.1    Weitzmann, M.N.2    Roggia, C.3
  • 29
    • 0034523328 scopus 로고    scopus 로고
    • TNF-α induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand
    • Lam J, Takeshita S, Barker JE, Kanagawa O, Ross FP and Teitelbaum SL: TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest 106: 1481-1488, 2000. (Pubitemid 32038586)
    • (2000) Journal of Clinical Investigation , vol.106 , Issue.12 , pp. 1481-1488
    • Lam, J.1    Takeshita, S.2    Barker, J.E.3    Kanagawa, O.4    Ross, F.P.5    Teitelbaum, S.L.6
  • 30
    • 0035808458 scopus 로고    scopus 로고
    • Tumor necrosis factor-α (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways
    • DOI 10.1074/jbc.M008198200
    • Zhang YH, Heulsmann A, Tondravi MM, Mukherjee A and Abu-Amer Y: Tumor necrosis factor-alpha (TNF) stimulates RANKL-induced osteoclastogenesis via coupling of TNF type 1 receptor and RANK signaling pathways. J Biol Chem 276: 563-568, 2001. (Pubitemid 32050352)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.1 , pp. 563-568
    • Zhang, Y.-H.1    Heulsmann, A.2    Tondravi, M.M.3    Mukherjee, A.4    Abu-Amer, Y.5
  • 31
    • 85047685623 scopus 로고    scopus 로고
    • TNFα potently activates osteoclasts, through a direct action independent of and strongly synergistic with RANKL
    • DOI 10.1210/en.143.3.1108
    • Fuller K, Murphy C, Kirstein B, Fox SW and Chambers TJ: TNFalpha potently activates osteoclasts, through a direct action independent of and strongly synergistic with RANKL. Endocrinology 143: 1108-1118, 2002. (Pubitemid 34164059)
    • (2002) Endocrinology , vol.143 , Issue.3 , pp. 1108-1118
    • Fuller, K.1    Murphy, C.2    Kirstein, B.3    Fox, S.W.4    Chambers, T.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.