Oral administration of phytocomponent p-hydroxycinnamic acid has a preventive effect on bone loss in streptozotocin-induced diabetic rats

International Journal of Molecular Medicine

Volumn 19, Issue 5, 2007, Pages 803-807

  Yamaguchi, Masayoshi ^a   Uchiyama, Satoshi ^a   Lai, Ying Ling ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Bone metabolism; Diabetes; Osteoporosis; p hydroxycinnamic acid; Rat femur

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; COUMARIC ACID; DNA; PHOSPHATE; PLANT MEDICINAL PRODUCT; STREPTOZOCIN; TRIACYLGLYCEROL;

ANIMAL; ARTICLE; BLOOD; BODY WEIGHT; DIAPHYSIS; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; OSTEOLYSIS; PHYTOTHERAPY; RAT; WISTAR RAT;

ADMINISTRATION, ORAL; ALKALINE PHOSPHATASE; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; BONE RESORPTION; CALCIUM; COUMARIC ACIDS; DIABETES MELLITUS, EXPERIMENTAL; DIAPHYSES; DNA; MALE; PHOSPHATES; PHYTOTHERAPY; PLANT PREPARATIONS; RATS; RATS, WISTAR; STREPTOZOCIN; TRIGLYCERIDES;

EID: 34248550073     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.19.5.803     Document Type: Article

References (24)

1. Nishimoto SK, Chang C-H, Gendler E, Stryker WF and Nimni ME: The effect of aging on bone formation in rats: Biochemical and histological evidence for decreased bone formation capacity. Calcif Tissue Int 37: 617-624, 1985.
2. Schapia C, Slinn S, Sarid M, Mokadi S, Kabala A and Slibermann M: Calcium and vitamin D enriched diets increase and preserve vertebral mineral content in aging laboratory rats. Bone 16: 575-582, 1995.
3. Wild RA, Buchamain JR, Myers C and Demers LM: Declining adrenal androgen: an association with bone loss in aging women. Proc Soc Exp Biol Med 186: 335-360, 1987.
4. Cooper C and Melton J III: Epidemiology of osteoporosis. Trends Endocrinol Metab 3: 1395-1445, 1996.
5. Bonjour J-P, Schurch M-A and Rozzori R: Nutritional aspects of hip fractures. Bone 18: 1395-1445, 1996.
6. Yamaguchi M: Isoflavone and bone metabolism: Its cellular mechanism and preventive role in bone loss. J Health Sci 48: 209-222, 2002.
7. Yamaguchi M: Regulatory mechanism of food factors in bone metabolism and prevention of osteoporosis. Yakugaku Zasshi 126: 1117-1137 , 2006.
8. Lee M-K, Park E-M, Bok S-H, Jung UJ, Kim J-Y, Park YB, Huh T-L, Kwon O-S and Choi M-S: Two cinnamate derivatives produce similar alteration in mRNA expression and activity of antioxidant enzymes in rats. J Biochem Mol Toxicol 17: 255-262, 2003.
9. Luceri C, Guglielmi F, Lodovici M, Giannimi L, Messerini L and Dolara P: Plant phenolic 4-coumaric acid protects against intestinal inflammation in rats. Scand J Gastroenterol 39: 1128-1133, 2004.
10. Lai YL and Yamaguchi M: Phytocomponent p-hydroxycinnamic acid stimulates bone formation and inhibits bone resorption in rat femoral tissues in vitro. Mol Cell Biochem 292: 45-52, 2006.
11. Lai YL and Yamaguchi M: Phytocomponent p-hydroxycinnamic acid inhibits osteoclast-like cell formation in mouse bone marrow cultures. Int J Mol Med 19: 123-128, 2007.
12. Lai YL and Yamaguchi M: Oral administration of phytocomponent p-hydroxycinnamic acid has anabolic effects on bone calcification in femoral tissues of rats in vivo. J Health Sci 52: 308-312, 2006. (Pubitemid 43824824)
13. Shires R, Teitelbaum SL, Bergfeld MA, Fallom MD, Statopolsky E and Avioli LV: The effect of streptozotocin-induced chronic diabetes mellitus on bone and mineral homeostasis in the rat. J Lab Clin Med 97: 231-240, 1981. (Pubitemid 11136127)
14. Bollen M, Miralpeix M, Venture F, Toth B, Bartrons R and Stalmans W: Oral administration of vanadate to streptozotocin-diabetic rats restores the glucose-induced activation of liver glycogen synthase. Biochem J 267: 269-271, 1990.
15. Yamaguchi M, Oishi H and Suketa Y: Stimulatory effect of zinc on bone formation in tissue culture. Biochem Pharmacol 36: 4007-4012, 1987.
16. Walter K and Schutt C: Acid and alkaline phosphatase in serum. In: Methods of Enzymatic Analysis. Bergmyer HU (ed). Vol. 1-2. Academic Press, New York, pp856-860, 1974.
17. Lowry OH, Rosenbrough NJ, Farr AL and Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-273, 1951.
18. Flanagan B and Nichols G Jr: Metabolic studies of bone in vitro. VI. Collagen biosynthesis by surviving bone fragment in vitro. J Biol Chem 237: 3386-3789, 1962.
19. Ceriotti G: Determination of nucleic acid in animal tissues. J Biol Chem 241: 39-77, 1955.
20. Levin ME, Boissesu VC and Avioli LV: Effect of diabetes mellitus on bone mass in juvenile and adult-onset diabetes. N Engl J Med 294: 241-245, 1976.
21. Schneider LE and Schel HP: Experimental diabetes reduces circulating 1,25-dihydroxyvitamin D in the rat. Science 196: 1452-1454, 1977.
22. Nyomba BL, Verhaeghe J, Thomasser M, Lissens W and Bouillon R: Bone mineral homeostasis in spontaneously diabetic BB rats. I. Abnormal vitamin D metabolism and impaired active intestinal calcium absorption. Endocrinology 124: 565-572, 1980.
23. Majeska RJ and Wuthier RE: Studies on matrix vesicles isolated from chick epiphyseal cartilage. Association of pyrophosphate and ATPase activities with alkaline phosphatase. Biochim Biophys Acta 391: 51-60, 1975.
24. Canalis E, Centrella M, Bunch W and McCarthy TL: Insulin-like growth factor-I mediates selective anabolic effects of parathyroid hormone in bone cultures. J Clin Invest 83: 60-65, 1989.